Susceptibility to pulmonary disease due to Mycobacterium avium-intracellulare complex may reflect low IL-17 and high IL-10 responses rather than Th1 deficiency

Clinical Immunology

Volumn 137, Issue 2, 2010, Pages 296-302

  Lim, Andrew ^a   Allison, Caris ^a   Price, Patricia ^a   Waterer, Grant ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Bronchiectasis; CD4+ T cells; Cytokines; Non tuberculous mycobacteria

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; MITOGENIC AGENT; STAPHYLOCOCCUS ENTEROTOXIN B; TUBERCULIN;

ADULT; AGED; ARTICLE; BRONCHIECTASIS; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; FEMALE; HUMAN; LUNG DISEASE; MALE; MYCOBACTERIUM INTRACELLULARE AVIUM; PRIORITY JOURNAL; TH1 CELL;

ADULT; ADULT CHILDREN; AGED; AGED, 80 AND OVER; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL COUNT; DISEASE SUSCEPTIBILITY; ENTEROTOXINS; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-5; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; TH1 CELLS; TH17 CELLS; TH2 CELLS; TUBERCULIN;

EID: 77957293601     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.07.011     Document Type: Article

References (24)

1. Marras T.K., Daley C.L. Epidemiology of human pulmonary infection with nontuberculous mycobacteria. Clin. Chest Med. 2002, 23:553-567.
2. Billinger M.E., Olivier K.N., Viboud C., et al. Nontuberculous mycobacteria-associated lung disease in hospitalized persons, United States, 1998-2005. Emerg. Infect. Dis. 2009, 15:1562-1569.
3. Hernandez-Garduno E., Rodrigues M., Elwood R.K. The incidence of pulmonary non-tuberculous mycobacteria in British Columbia, Canada. Int. J. Tuberc. Lung Dis. 2009, 13:1086-1093.
4. Griffith D.E., Aksamit T., Brown-Elliott B.A., et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am. J. Respir. Crit. Care Med. 2007, 175:367-416.
5. Sexton P., Harrison A.C. Susceptibility to nontuberculous mycobacterial lung disease. Eur. Respir. J. 2008, 31:1322-1333.
6. Iseman M.D., Buschman D.L., Ackerson L.M. Pectus excavatum and scoliosis. Thoracic anomalies associated with pulmonary disease caused by Mycobacterium avium complex. Am. Rev. Respir. Dis. 1991, 144:914-916.
7. Kim R.D., Greenberg D.E., Ehrmantraut M.E., et al. Pulmonary nontuberculous mycobacterial disease: prospective study of a distinct preexisting syndrome. Am. J. Respir. Crit. Care Med. 2008, 178:1066-1074.
8. Greinert U., Schlaak M., Rusch-Gerdes S., Flad H.D., Ernst M. Low in vitro production of interferon-gamma and tumor necrosis factor-alpha in HIV-seronegative patients with pulmonary disease caused by nontuberculous mycobacteria. J. Clin. Immunol. 2000, 20:445-452.
9. Kwon Y.S., Kim E.J., Lee S.H., et al. Decreased cytokine production in patients with nontuberculous mycobacterial lung disease. Lung 2007, 185:337-341.
10. Ryu Y.J., Kim E.J., Lee S.H., et al. Impaired expression of Toll-like receptor 2 in nontuberculous mycobacterial lung disease. Eur. Respir. J. 2007, 30:736-742.
11. Vankayalapati R., Wizel B., Samten B., et al. Cytokine profiles in immunocompetent persons infected with Mycobacterium avium complex. J. Infect. Dis. 2001, 183:478-484.
12. Wilton S., Cousins D. Detection and identification of multiple mycobacterial pathogens by DNA amplification in a single tube. PCR Methods Appl. 1992, 1:269-273.
13. Sweet L., Singh P.P., Azad A.K., Rajaram M.V., Schlesinger L.S., Schorey J.S. Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids. Infect. Immun. 2010, 78:518-526.
14. Dlugovitzky D., Bay M.L., Rateni L., et al. Influence of disease severity on nitrite and cytokine production by peripheral blood mononuclear cells (PBMC) from patients with pulmonary tuberculosis (TB). Clin. Exp. Immunol. 2000, 122:343-349.
15. Lienhardt C., Azzurri A., Amedei A., et al. Active tuberculosis in Africa is associated with reduced Th1 and increased Th2 activity in vivo. Eur. J. Immunol. 2002, 32:1605-1613.
16. Sasaki S., Takeshita F., Okuda K., Ishii N. Mycobacterium leprae and leprosy: a compendium. Microbiol. Immunol. 2001, 45:729-736.
17. Khader S.A., Bell G.K., Pearl J.E., et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 2007, 8:369-377.
18. Scriba T.J., Kalsdorf B., Abrahams D.A., et al. Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J. Immunol. 2008, 180:1962-1970.
19. Umemura M., Yahagi A., Hamada S., et al. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J. Immunol. 2007, 178:3786-3796.
20. Peng M.Y., Wang Z.H., Yao C.Y., et al. Interleukin 17-producing gamma delta T cells increased in patients with active pulmonary tuberculosis. Cell. Mol. Immunol. 2008, 5:203-208.
21. Simonian P.L., Roark C.L., Born W.K., O'Brien R.L., Fontenot A.P. Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis. Transl. Res. 2009, 154:222-227.
22. Aujla S.J., Dubin P.J., Kolls J.K. Interleukin-17 in pulmonary host defense. Exp. Lung Res. 2007, 33:507-518.
23. Nembrini C., Marsland B.J., Kopf M. IL-17-producing T cells in lung immunity and inflammation. J. Allergy Clin. Immunol. 2009, 123:986-994.
24. Lockhart E., Green A.M., Flynn J.L. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J. Immunol. 2006, 177:4662-4669.