Anticonvulsant potential of Anisomeles malabarica leaves against experimentally induced convulsions in rats

International Journal of Green Pharmacy

Volumn 4, Issue 3, 2010, Pages 199-205

  Singh, Ishpinder ^a   Singh, Manjit ^a   Singh, Tajinder ^a   Bijjem, Krishna Reddy V ^a   Kalia, Ajudhia N ^a  

^a ISF COLLEGE OF PHARMACY   (India)

Author keywords

Anisomeles malabarica leaves; chloroform extract and ethyl acetate extract; convulsions; maximal electroshock; pentylenetetrazole

Indexed keywords

ACETIC ACID ETHYL ESTER; ANISOMELES MALABARICA EXTRACT; ANTICONVULSIVE AGENT; CHLOROFORM; DIAZEPAM; METHANOL; PENTETRAZOLE; PHENYTOIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVULSION; LOCOMOTION; MALE; NONHUMAN; PHYTOCHEMISTRY; PLANT LEAF; RAT; ROTAROD TEST;

EID: 77957287797     PISSN: 09738258     EISSN: 19984103     Source Type: Journal    
DOI: 10.4103/0973-8258.69182     Document Type: Article

References (40)

1. Dhanabal SP, Paramakrishnan N, Manimaran S, Suresh B. Anticonvulsant potential of essential oil of Artemisia abrotanum. Curr Trends Biotechnol Pharm 2007;1:112-116
2. de Sousa DP, Goncalves JC, Quintans-Júnior L, Cruz JS, Araújo DA, de Almeida RN. Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents. Neurosci Lett 2006;401:231-235
3. Sonavane GS, Palekar RC, Kasture VS, Kasture SB. Anticonvulsant and behavioural actions of Myristica fragrans seeds. Indian J Pharmacol 2002;34:332-338
4. Gupta AK, Tandon N. Anisomeles malabarica. In: Gupta AK, Tandon N, editors. Reviews on Indian Medicinal Plants. New Delhi: Indian Council of Medical Research (ICMR); 2004. p. 343-349
5. Ramachandran K. Anisomeles malabarica. In: Ramachandran K, editor. The Wealth of India: A dictionary of Indian Raw Materials and Industrial Products. New Delhi: Publications and Information Directorate, Council for Scientific and Industrial Research (CSIR); 1985. p. 278.
6. Apparananthem T, Chelladurai V, Subramanian V. Some tribal folk medicines of point calimere (Kodikkarai) in Tamil Nadu. Bull Med Ethnobot Res 1982;3:173-177
7. Tripathi YC, Prabhu VV, Pal RS, Mishra RN. Medicinal plants of Rajasthan in Indian system of medicine. Anc Sci Life 1996;15: 190-212.
8. Reddy MB, Reddy KR, Reddy MN. Ethnobotany of Cuddapah district, Andhra Pradesh, India. Indian J Pharmacog 1991;29: 273-280
9. Harborne JB. Triterpenes. In: Harborne JB, editor. Phytochemical methods: A guide to modern techniques of plant analysis. 3rd ed. London: Chapman and Hall publishers; 1998. p. 77-78
10. Ikhiri K, Boureima D, Dan-Kouloudo D. Chemical screening of medicinal plants used in traditional pharmacopoeia of Niger. Intl J Pharmacog 1992;30:251-262 (Pubitemid 23126667)
11. Kulkarni SK. Actions of clonidine on convulsions and behaviour. Arch Int Pharmacodyn Ther 1981;252:124-132
12. Krall RL, Penry JK, White BG, Kupferberg HJ, Swinyard EA. Antiepileptic drug development 2. Anticonvulsant drug screening. Epilepsia 1978;19:409-428 (Pubitemid 9016848)
13. Misra AK, Dandiya PC, Kulkarni SK. Anticonvulsant activity of some trimethoxybenzylidene-2-thiohydantoin derivatives. Indian J Pharmacol 1973;5:449-450
14. Rao VS, Rao A, Karanth KS. Anticonvulsant and neurotoxicity profile of Nardostachys jatamansi in rats. J Ethnopharmacol 2005;102:351-356 (Pubitemid 41571840)
15. Obay BD, Tasdemir E, Tümer C, Bilgin HM, Sermet A. Antiepileptic effects of ghrelin on pentylenetetrazole-induced seizures in rats. Peptides 2007;28:1214-1219 (Pubitemid 46843389)
16. Contreras CM, Chacon L, Enriquez RG. Anticonvulsant properties of Ipomoea stans. Phytomed 1996;3:41-44 (Pubitemid 126491950)
17. Felipe FC, Filho JT, Souza LE, Silveira JA, Uchoa DE, Silveira ER, et al. Piplartine an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice. Phytomed 2007;14:605-612
18. Löscher W, Hönack D, Fassbender CP, Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs III. Pentylenetetrazole seizure models. Epilepsy Res 1991b;8:171-189
19. Adzu B, Amos S, Dzarma S, Wambebe C, Gamaniel K. Effect of zizyphus spina-christi wild on the central nervous system in mice. J Ethnopharmacol 2002;79:13-16 (Pubitemid 34017234)
20. Kulkarni SK, Dandiya PC. Influence of intraventricular a d m i n i s t r a t i o n o f n o r e p i n e p h r i n e , d o p a m i n e a n d 5-hydroxytrytamine on motor activity of rats. Indian J Med Res 1975;63:462-468
21. Schachter SC. Tiagabine monotherapy in the treatment of partial epilepsy. Epilepsia 1995;36:S2-6.
22. White HS. New mechanisms of antiepileptic drugs. In: Porter R, Chadwick D, editors. Epilepsies II. Boston: Butterworth Heinemann; 1997. p. 1-30.
23. Oliveira FA, De Almeida RN, Sousa MF, Barbosa-Filho JM, Diniz SA, De Medeiros IA. Anticonvulsant properties of N-salicyloyltryptamine in mice. Pharmacol Biochem Behav 2001;68:199-202.
24. Nsour WM, Lau CB, Wong IC. Review on phytotherapy in epilepsy. Seizure 2000;9:96-107.
25. Meldrum BS. GABA agonists as antiepileptic agents. Adv Biochem Psychopharmacol 1981;26:207-217
26. Westmoreland BF, Benarroch EE, Dube JR, Regan TJ, Sandok BA. Medicinal neurosciences. Rochester: Margo Foundation; 1994. p. 307-312
27. Nevins ME, Arnolde SM. A comparison of the anticonvulsant effects of competitive and non-competitive antagonists of the N-methyl-D-aspartate receptor. Brain Res 1989;503:1-4. (Pubitemid 19279327)
28. Velisek L, Kusa R, Kulovana M, Mares P. Excitatory amino acid antagonists and pentylenetetrazole-induced seizures during ontogenesis. The effects of 2-amino-7-phosphonoheptanoate. Life Sci 1990;46:1349-1357 (Pubitemid 20169718)
29. Ankica J, Marina J, Milica N, Maksimovic M, Boskovic B. Nitric oxide (NO) and an NMDA receptor antagonist in pentylenetetrazole-induced convulsions. Acta Veterinaria (Beograd) 2003;53:103-112 (Pubitemid 36843242)
30. Aricioglu F, Kan B, Yillar O, Korcegez E, Berkman K. Effect of agmatine on electrically and chemically induced seizures in mice. Ann N Y Acad Sci 2003;1009:141-146 (Pubitemid 38265099)
31. Rang HP, Dale MM, Ritter JM, Moore PK. Amino acid transmitters. In: Rang HP, Dale MM, Ritter JM, Moore PK, editors. Pharmacology. Noida: International Print-O-Pac Limited; 2006. p. 479-491
32. Barreto PS, Lemos T, Morato GS. NMDA-receptor antagonists block the development of rapid tolerance to ethanol in mice. Addict Biol 2006;3:55-64.
33. Dar MS. Mouse cerebellar adenosine-glutamate interactions and modulation of ethanol-induced motor incoordination. Alcohol Clin Exp Res 2002;26:1395-1403
34. Löscher W. Pharmacology of glutamate receptor antagonists in the kindling model of epilepsy. Prog Neurobiol 1998;54:721-741 (Pubitemid 28137704)
35. Turski L, Schwarz M, Sontag KH. Interaction between phenytoin and diazeoam in mutant Han-Wistar rats with progressive spastic paresis. Naunyn Schmiedebergs Arch Pharmacol 1982;321:48-51. (Pubitemid 12036171)
36. Hosseinzadeh H, Parvaedeh S. Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice. Phytomed 2004;11:56-64. (Pubitemid 38196797)
37. Chauhan AK, Dobhal MP, Joshio BC. A review of medicinal plant showing anticonvulsant activity. J Ethnopharmacol 1988;22: 11-23.
38. Brum LF, Elisabetsky E, Souza D. Effects of linaloolon [(3) H] MK801 and [3(3)H] muscimol binding in mouse cortical membranes. Phytother Res 2001;15:422-425 (Pubitemid 32762391)
39. Meckes M, Clazado F, Tortoreillo J, Gonzalez H, Martinez M. Terpenoid isolated from Psidium guajava hexane extract with depressant activity on central nervous system. Phyto Res 1996;10:600-603 (Pubitemid 26382310)
40. Fernández SP, Wasowski C, Loscalzo LM, Granger RE, Johnston GA, Paladini AC, et al. Central nervous system depressant action of flavonoid glycosides. Eur J Pharmacol 2006;539:168-176 (Pubitemid 44208813)