메뉴 건너뛰기




Volumn 30, Issue 5, 2010, Pages 518-525

A randomized, double-blind comparison of risperidone versus low-dose risperidone plus low-dose haloperidol in treating schizophrenia

Author keywords

antipsychotic drug combination; haloperidol; risperidone; schizophrenia

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BIPERIDEN; HALOPERIDOL; RISPERIDONE;

EID: 77957287124     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e3181f28dff     Document Type: Article
Times cited : (28)

References (48)
  • 1
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • DOI 10.1038/sj.mp.4001556
    • Miyamoto S, Duncan GE, Marx CE, et al. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry. 2005;10: 79-104. (Pubitemid 40139590)
    • (2005) Molecular Psychiatry , vol.10 , Issue.1 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 2
    • 58049157203 scopus 로고    scopus 로고
    • Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis
    • Leucht S, Corves C, Arbter D, et al. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet. 2009;373: 31-41.
    • (2009) Lancet , vol.373 , pp. 31-41
    • Leucht, S.1    Corves, C.2    Arbter, D.3
  • 3
    • 0038653525 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of second-generation antipsychotics
    • DOI 10.1001/archpsyc.60.6.553
    • Davis JM, Chen N, Glick ID. A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry. 2003;60: 553-564. (Pubitemid 36682312)
    • (2003) Archives of General Psychiatry , vol.60 , Issue.6 , pp. 553-564
    • Davis, J.M.1    Chen, N.2    Glick, I.D.3
  • 4
    • 8744294887 scopus 로고    scopus 로고
    • Quality of life outcomes of risperidone, olanzapine, and typical antipsychotics among schizophrenia patients treated in routine clinical practice: A naturalistic comparative study
    • DOI 10.1097/01.jcp.0000144895.75728.2b
    • Ritsner M, Gibel A, Perelroyzen G, et al. Quality of life outcomes of risperidone, olanzapine, and typical antipsychotics among schizophrenia patients treated in routine clinical practice: a naturalistic comparative study. J Clin Psychopharmacol. 2004;24: 582-591. (Pubitemid 39518652)
    • (2004) Journal of Clinical Psychopharmacology , vol.24 , Issue.6 , pp. 582-591
    • Ritsner, M.1    Gibel, A.2    Perelroyzen, G.3    Kurs, R.4    Jabarin, M.5    Ratner, Y.6
  • 6
    • 26844433208 scopus 로고    scopus 로고
    • Antipsychotic monotherapy and polypharmacy in the naturalistic treatment of schizophrenia with atypical antipsychotics
    • DOI 10.1186/1471-244X-5-26
    • Faries D, Ascher-Svanum H, Zhu B, et al. Antipsychotic monotherapy and polypharmacy in the naturalistic treatment of schizophrenia with atypical antipsychotics. BMC Psychiatry. 2005;5: 26. (Pubitemid 41460700)
    • (2005) BMC Psychiatry , vol.5 , pp. 26
    • Faries, D.E.1    Ascher-Svanum, H.2    Zhu, B.3    Correll, C.U.4    Kane, J.5
  • 7
    • 0035988577 scopus 로고    scopus 로고
    • Combination antipsychotics: Pros, cons, and questions
    • Miller AL, Craig CS. Combination antipsychotics: pros, cons, and questions. Schizophr Bull. 2002;28: 105-109.
    • (2002) Schizophr Bull , vol.28 , pp. 105-109
    • Miller, A.L.1    Craig, C.S.2
  • 9
    • 0037278766 scopus 로고    scopus 로고
    • Antipsychotic medication coprescribing in a large state hospital system
    • DOI 10.1002/pds.783
    • Jaffe AB, Levine J. Antipsychotic medication coprescribing in a large state hospital system. Pharmacoepidemiol Drug Saf. 2003;12: 41-48. (Pubitemid 36192948)
    • (2003) Pharmacoepidemiology and Drug Safety , vol.12 , Issue.1 , pp. 41-48
    • Jaffe, A.B.1    Levine, J.2
  • 10
    • 12944304694 scopus 로고    scopus 로고
    • Prevalence, trends, and factors associated with antipsychotic polypharmacy among Medicaid-eligible schizophrenia patients, 1998-2000
    • Ganguly R, Kotzan JA, Miller LS, et al. Prevalence, trends, and factors associated with antipsychotic polypharmacy among Medicaid-eligible schizophrenia patients, 1998-2000. J Clin Psychiatry. 2004;65: 1377-1388.
    • (2004) J Clin Psychiatry , vol.65 , pp. 1377-1388
    • Ganguly, R.1    Kotzan, J.A.2    Miller, L.S.3
  • 11
    • 1842533044 scopus 로고    scopus 로고
    • Multiple versus single antipsychotic agents for hospitalized psychiatric patients: Case-control study of risks versus benefits
    • DOI 10.1176/appi.ajp.161.4.700
    • Centorrino F, Goren JL, Hennen J, et al. Multiple versus single antipsychotic agents for hospitalized psychiatric patients: case-control study of risks versus benefits. Am J Psychiatry. 2004;161: 700-706. (Pubitemid 38445515)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.4 , pp. 700-706
    • Centorrino, F.1    Goren, J.L.2    Hennen, J.3    Salvatore, P.4    Kelleher, J.P.5    Baldessarini, R.J.6
  • 12
    • 0035988519 scopus 로고    scopus 로고
    • Recent trends in antipsychotic combination therapy of schizophrenia and schizoaffective disorder: Implications for state mental health policy
    • Clark RE, Bartels SJ, Mellman TA, et al. Recent trends in antipsychotic combination therapy of schizophrenia and schizoaffective disorder: implications for state mental health policy. Schizophr Bull. 2002;28: 75-84.
    • (2002) Schizophr Bull , vol.28 , pp. 75-84
    • Clark, R.E.1    Bartels, S.J.2    Mellman, T.A.3
  • 14
  • 15
    • 0026410773 scopus 로고
    • Optimal dose of neuroleptic in acute schizophrenia. A controlled study of the neuroleptic threshold and higher haloperidol dose
    • McEvoy JP, Hogarty GE, Steingard S. Optimal dose of neuroleptic in acute schizophrenia. A controlled study of the neuroleptic threshold and higher haloperidol dose. Arch Gen Psychiatry. 1991;48: 739-745.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 739-745
    • McEvoy, J.P.1    Hogarty, G.E.2    Steingard, S.3
  • 16
    • 0032982714 scopus 로고    scopus 로고
    • 2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia
    • Kapur S, Zipursky RB, Remington G. Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. Am J Psychiatry. 1999;156: 286-293. (Pubitemid 29077120)
    • (1999) American Journal of Psychiatry , vol.156 , Issue.2 , pp. 286-293
    • Kapur, S.1    Zipursky, R.B.2    Remington, G.3
  • 17
    • 0003706599 scopus 로고    scopus 로고
    • 4th ed. Washington, DC: American Psychiatric Publishing, Inc
    • Schatzberg A, Nemeroff C. Textbook of Psychopharmacology. 4th ed. Washington, DC: American Psychiatric Publishing, Inc; 2009: 627-640.
    • (2009) Textbook of Psychopharmacology , pp. 627-640
    • Schatzberg, A.1    Nemeroff, C.2
  • 18
    • 0004085199 scopus 로고
    • American Psychiatric Association Washington DC: American Psychiatric Press
    • American Psychiatric Association. Structured Clinical Interview for DSM-IV. Washington, DC: American Psychiatric Press; 1994.
    • (1994) Structured Clinical Interview for DSM-IV
  • 20
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, et al. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry. 1988;45: 789-796.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3
  • 21
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13: 261-276. (Pubitemid 18039085)
    • (1987) Schizophrenia Bulletin , vol.13 , Issue.2 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 22
    • 0028031780 scopus 로고
    • Specificity of the Calgary Depression Scale for schizophrenics
    • DOI 10.1016/0920-9964(94)90017-5
    • Addington D, Addington J, Maticka-Tyndale E. Specificity of the Calgary Depression Scale for schizophrenics. Schizophr Res. 1994;11: 239-244. (Pubitemid 24063743)
    • (1994) Schizophrenia Research , vol.11 , Issue.3 , pp. 239-244
    • Addington, D.1    Addington, J.2    Maticka-Tyndale, E.3
  • 23
    • 0036264065 scopus 로고    scopus 로고
    • Global Assessment of Functioning ratings and the allocation and outcomes of mental health services
    • Moos RH, Nichol AC, Moos BS. Global Assessment of Functioning ratings and the allocation and outcomes of mental health services. Psychiatr Serv. 2002;53: 730-737.
    • (2002) Psychiatr Serv , vol.53 , pp. 730-737
    • Moos, R.H.1    Nichol, A.C.2    Moos, B.S.3
  • 24
    • 0024358369 scopus 로고
    • A rating scale for drug-induced akathisia
    • Barnes TR. A rating scale for drug-induced akathisia. Br J Psychiatry. 1989;154: 672-676.
    • (1989) Br J Psychiatry , vol.154 , pp. 672-676
    • Barnes, T.R.1
  • 25
    • 0014723449 scopus 로고
    • A rating scale for extrapyramidal side effects
    • Simpson GM, Angus JW. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand. 1970;212: 11-19.
    • (1970) Acta Psychiatr Scand , vol.212 , pp. 11-19
    • Simpson, G.M.1    Angus, J.W.2
  • 26
    • 0023244845 scopus 로고
    • A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients
    • The UKU Side Effect Rating Scale
    • Lingjaerde O, Ahlfors UG, Bech P, et al. The UKU Side Effect Rating Scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand. 1987;334(suppl): 1-100.
    • (1987) Acta Psychiatr Scand , vol.334 , Issue.SUPPL. , pp. 1-100
    • Lingjaerde, O.1    Ahlfors, U.G.2    Bech, P.3
  • 27
    • 0026667228 scopus 로고
    • Validating the SF-36 health survey questionnaire: New outcome measure for primary care
    • Brazier JE, Harper R, Jones NM, et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305: 160-164.
    • (1992) BMJ , vol.305 , pp. 160-164
    • Brazier, J.E.1    Harper, R.2    Jones, N.M.3
  • 28
    • 33747170572 scopus 로고    scopus 로고
    • Comparison of quetiapine and risperidone in the treatment of schizophrenia: A randomized, double-blind, flexible-dose, 8-week study
    • Zhong KX, Sweitzer DE, Hamer RM, et al. Comparison of quetiapine and risperidone in the treatment of schizophrenia: a randomized, double-blind, flexible-dose, 8-week study. J Clin Psychiatry. 2006;67: 1093-1103.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1093-1103
    • Zhong, K.X.1    Sweitzer, D.E.2    Hamer, R.M.3
  • 30
  • 31
    • 0029026941 scopus 로고
    • The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: A PET study
    • Kapur S, Remington G, Zipursky RB, et al. The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study. Life Sci. 1995;57: 103-107.
    • (1995) Life Sci , vol.57 , pp. 103-107
    • Kapur, S.1    Remington, G.2    Zipursky, R.B.3
  • 32
    • 33845661499 scopus 로고    scopus 로고
    • Measurement-based psychiatry: Definitions of response, remission, stability, and relapse in schizophrenia
    • Leucht S, Kane JM. Measurement-based psychiatry: definitions of response, remission, stability, and relapse in schizophrenia. J Clin Psychiatry. 2006;67: 1813-1814. (Pubitemid 44955164)
    • (2006) Journal of Clinical Psychiatry , vol.67 , Issue.11 , pp. 1813-1814
    • Leucht, S.1    Kane, J.M.2
  • 33
    • 27744529018 scopus 로고    scopus 로고
    • Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: A randomized, double-blind, placebo-controlled study
    • Lane HY, Chang YC, Liu YC, et al. Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. Arch Gen Psychiatry. 2005;62: 1196-1204.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1196-1204
    • Lane, H.Y.1    Chang, Y.C.2    Liu, Y.C.3
  • 34
    • 8644255026 scopus 로고    scopus 로고
    • Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: Comparison with risperidone and chlorpromazine
    • DOI 10.1007/s00213-004-1866-y
    • Tada M, Shirakawa K, Matsuoka N, et al. Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine. Psychopharmacology (Berl). 2004;176: 94-100. (Pubitemid 39506372)
    • (2004) Psychopharmacology , vol.176 , Issue.1 , pp. 94-100
    • Tada, M.1    Shirakawa, K.2    Matsuoka, N.3    Mutoh, S.4
  • 35
    • 0033996265 scopus 로고    scopus 로고
    • Risperidone in acutely exacerbated schizophrenia: Dosing strategies and plasma levels
    • Lane HY, Chiu WC, Chou JC, et al. Risperidone in acutely exacerbated schizophrenia: dosing strategies and plasma levels. J Clin Psychiatry. 2000;61: 209-214.
    • (2000) J Clin Psychiatry , vol.61 , pp. 209-214
    • Lane, H.Y.1    Chiu, W.C.2    Chou, J.C.3
  • 36
    • 0035022719 scopus 로고    scopus 로고
    • Optimal dosing with risperidone: Updated recommendations
    • Williams R. Optimal dosing with risperidone: updated recommendations. J Clin Psychiatry. 2001;62: 282-289. (Pubitemid 32428768)
    • (2001) Journal of Clinical Psychiatry , vol.62 , Issue.4 , pp. 282-289
    • Williams, R.1
  • 37
    • 33645220629 scopus 로고    scopus 로고
    • Establishing a dose-response relationship for oral risperidone in relapsed schizophrenia
    • Ezewuzie N, Taylor D. Establishing a dose-response relationship for oral risperidone in relapsed schizophrenia. J Psychopharmacol. 2006;20: 86-90.
    • (2006) J Psychopharmacol , vol.20 , pp. 86-90
    • Ezewuzie, N.1    Taylor, D.2
  • 38
    • 0038266756 scopus 로고    scopus 로고
    • Chlorpromazine equivalent doses for the newer atypical antipsychotics
    • Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry. 2003;64: 663-667.
    • (2003) J Clin Psychiatry , vol.64 , pp. 663-667
    • Woods, S.W.1
  • 39
    • 0032072886 scopus 로고    scopus 로고
    • New atypical antipsychotic medications
    • DOI 10.1016/S0022-3956(98)00023-5, PII S00223956980002358
    • Jibson MD, Tandon R. New atypical antipsychotic medications. J Psychiatr Res. 1998;32: 215-228. (Pubitemid 28409549)
    • (1998) Journal of Psychiatric Research , vol.32 , Issue.3-4 , pp. 215-228
    • Jibson, M.D.1    Tandon, R.2
  • 41
    • 1442357994 scopus 로고    scopus 로고
    • Prolactin levels in schizophrenia and schizoaffective disorder patients treated with clozapine, olanzapine, risperidone, or haloperidol
    • Volavka J, Czobor P, Cooper TB, et al. Prolactin levels in schizophrenia and schizoaffective disorder patients treated with clozapine, olanzapine, risperidone, or haloperidol. J Clin Psychiatry. 2004;65: 57-61.
    • (2004) J Clin Psychiatry , vol.65 , pp. 57-61
    • Volavka, J.1    Czobor, P.2    Cooper, T.B.3
  • 42
    • 0036721406 scopus 로고    scopus 로고
    • The differential effects of atypical antipsychotics on prolactin elevation are explained by their differential blood-brain disposition: A pharmacological analysis in rats
    • DOI 10.1124/jpet.102.035303
    • Kapur S, Langlois X, Vinken P, et al. The differential effects of atypical antipsychotics on prolactin elevation are explained by their differential blood-brain disposition: a pharmacological analysis in rats. J Pharmacol Exp Ther. 2002;302: 1129-1134. (Pubitemid 34920235)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.3 , pp. 1129-1134
    • Kapur, S.1    Langlois, X.2    Vinken, P.3    Megens, A.A.H.P.4    De Coster, R.5    Andrews, J.S.6
  • 43
    • 5444267926 scopus 로고    scopus 로고
    • 3 dopamine receptor occupancy in amisulpride treated patients
    • DOI 10.1007/s00213-004-1826-6
    • Bressan RA, Erlandsson K, Spencer EP, et al. Prolactinemia is uncoupled from central D2/D3 dopamine receptor occupancy in amisulpride treated patients. Psychopharmacology (Berl). 2004;175: 367-373. (Pubitemid 39361925)
    • (2004) Psychopharmacology , vol.175 , Issue.3 , pp. 367-373
    • Bressan, R.A.1    Erlandsson, K.2    Spencer, E.P.3    Ell, P.J.4    Pilowsky, L.S.5
  • 46
    • 0003706599 scopus 로고    scopus 로고
    • Schatzberg A, Nemeroff C, eds. 4th ed. Washington, DC: American Psychiatric Publishing, Inc
    • Schatzberg A, Nemeroff C, eds. Textbook of psychopharmacology. 4th ed. Washington, DC: American Psychiatric Publishing, Inc; 2009: 533-554.
    • (2009) Textbook of Psychopharmacology , pp. 533-554
  • 47
    • 67649222011 scopus 로고    scopus 로고
    • Lurasidone in the treatment of acute schizophrenia: A double-blind, placebo-controlled trial
    • Nakamura M, Ogasa M, Guarino J, et al. Lurasidone in the treatment of acute schizophrenia: a double-blind, placebo-controlled trial. J Clin psychiatry. 2009;70: 829-836.
    • (2009) J Clin Psychiatry , vol.70 , pp. 829-836
    • Nakamura, M.1    Ogasa, M.2    Guarino, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.