Sarcoplasmic reticulum Ca2+ pumping kinetics regulates timing of local Ca2+releases and spontaneous beating rate of rabbit sinoatrial node pacemaker cells

Circulation Research

Volumn 107, Issue 6, 2010, Pages 767-775

  Vinogradova, Tatiana M ^a   Brochet, Didier X P ^a   Sirenko, Syevda ^a   Li, Yue ^a   Spurgeon, Harold ^a   Lakatta, Edward G ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

adrenergic receptor signaling; sarcoplasmic reticulum Ca2+ pumping; sinoatrial nodal pacemaker cells

Indexed keywords

BETA ADRENERGIC RECEPTOR; CALCIUM; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLOPIAZONIC ACID; PHOSPHODIESTERASE; PHOSPHOLAMBAN; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM;

ACTION POTENTIAL; ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM DEPLETION; CALCIUM TRANSPORT; CELL CYCLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEPOLARIZATION; NONHUMAN; PACEMAKER NERVE CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; SINUS NODE; WESTERN BLOTTING; ANIMAL; BIOLOGICAL RHYTHM; CALCIUM SIGNALING; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART RATE; METABOLISM; PHYSIOLOGY; RABBIT; SECRETION; TIME;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM SIGNALING; HEART RATE; RABBITS; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SINOATRIAL NODE; TIME FACTORS;

EID: 77957283607     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.220517     Document Type: Article

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