Enhancement of sustained and controlled protein release using polyelectrolyte complex-loaded injectable and thermosensitive hydrogel

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 2, 2010, Pages 179-188

  Park, Mi Ran ^a,b   Chun, ChangJu ^a   Cho, Chong Su ^b,c   Song, Soo Chang ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Electrostatic interaction; Injectable gel depot system; Poly(organophosphazenes); Polyelectrolyte complex (PEC); Sustained protein delivery; Thermosensitive hydrogel

Indexed keywords

AMINE; AMYLASE; BOVINE SERUM ALBUMIN; GELATIN; GELATIN TYPE B 75 BLOOM; HUMAN GROWTH HORMONE; ORGANOPHOSPHATE; POLYARGININE; POLYELECTROLYTE; POLYETHYLENEIMINE; POLYLYSINE; PROTAMINE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED RELEASE FORMULATION; DIFFUSION; DRUG DELIVERY SYSTEM; HEAT SENSITIVITY; HYDRODYNAMICS; HYDROGEL; MOLECULAR INTERACTION; MOLECULAR SIZE; MOLECULAR WEIGHT; PARTICLE SIZE; SUSTAINED RELEASE FORMULATION; VISCOSITY;

CATIONS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; ELECTROLYTES; HYDROGELS; MOLECULAR WEIGHT; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; PROTEINS; STATIC ELECTRICITY; TEMPERATURE; TIME FACTORS; VISCOSITY;

EID: 77957278109     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.06.012     Document Type: Article

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