Controlled release of proteins from dextran hydrogels

Journal of Controlled Release

Volumn 39, Issue 1, 1996, Pages 47-55

  Hennink, W E ^a   Talsma, H ^a   Borchert, J C H ^a   De Smedt, S C ^b   Demeester, J ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Dextram; Hydrogel; Mesh size; Protein; Protein release

Indexed keywords

4 DIMETHYLAMINOPYRIDINE; BOVINE SERUM ALBUMIN; DEXTRAN; DIMETHYL SULFOXIDE; GLYCIDYL METHACRYLATE; IMMUNOGLOBULIN G; LYSOZYME; PROTEIN; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG RELEASE; HYDROGEL; PHARMACEUTICS; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; THEORY;

EID: 0029892147     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00132-8     Document Type: Article

References (27)

1. R. Langer, Biomaterials in controlled drug delivery: new perspectives from biotechnological advances, Pharm. Technol. August (1989) 22-26.
2. J.E. Talmadge, The pharmaceutics and delivery of therapeutic polypeptides and proteins, Adv. Drug Deliv. Rev. 10 (1993) 247-299.
3. V.H. Lee, Peptide and Protein Drug Delivery, Marcel Dekker Inc., New York, 1990.
4. S.W. Kim, Y.H. Bae and T. Okano. Hydrogels: swelling, drug loading and release, Pharm. Res. 9 (1992) 283-290.
5. K. Park, W.S.W. Shalaby and H. Park, Biodegradable Hydrogels for Drug Delivery, Technomic Publishing, Basel, Switzerland, 1993.
6. W.N.E. van Dijk-Wolthuis, H. Talsma, J.J. Kettenes-van den Bosch, M.J. van Steenbergen and W.E. Hennink, Synthesis, characterization and polymerization of glycidyl methacrylate derivatized dextran, Macromolecules 28 (1995) 6317-6322.
7. N.A. Peppas and S.R. Lustig, Solute diffusion in hydrophilic network structures, in: N.A. Peppas (Ed.), Hydrogels in Medicine and Pharmacy, Vol. I, CRC Press, Boca Raton, FL, 1986, pp. 57-83.
8. S. Sato and S.W. Kim, Macromolecular diffusion through polymer membranes, Int. J. Pharm. 22 (1984) 229-255.
9. D.L. Gilbert, T. Okano, T. Miyata and S.W. Kim, Macromolecular diffusion through collagen membranes, Int. J. Pharm. 47 (1988) 79-88.
10. H. Feil, Y.H. Bae, J. Feijen and S.W. Kim, Molecular separation by thermosensitive hydrogel membranes, J. Membr. Sci. 64 (1991) 283-294.
11. S. Wisniewski and S.W. Kim, Permeation of water-soluble solutes through poly(2-hydroxyethylmethacrylate) and poly(2-hydroxyethylmethacrylate) crosslinked with ethylene glycol dimethacrylate, J. Membr. Sci. 6 (1980) 299-308.
12. N.A. Peppas and B.D. Barr-Howell, Characterisation of the cross-linked structure of hydrogels, in: N.A. Peppas (Ed.), Hydrogels in Medicine and Pharmacy, Vol. I, CRC Press, Boca Raton, FL, 1986, pp. 27-57.
13. E.W. Merrill, K.A. Dennison and C. Sung, Partitioning and diffusion of solutes in hydrogels of poly(ethylene oxide), Biomaterials 14 (1993) 1117-1126.
14. K. Burczak, T. Fujisato, M. Hatada and Y. Ikada, Protein permeation through poly(vinyl alcohol) hydrogel membranes, Biomaterials 15 (1994) 231-238.
15. M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72 (1976) 248-254.
16. R.W. Baker and H.K. Lonsdale, Controlled release: mechanisms and rates, in: A.C. Tanquary and R.E. Lacey (Eds), Advances in Experimental Medicine and Biology, Vol. 47, Plenum Press, New York, 1974, pp. 15-73.
17. N.A. Peppas, H.J. Moynihan and L.M. Lucht, The structure of highly crosslinked poly(2-hydroxyethylmethacrylate) hydrogels. J. Biomed. Mater. Res. 19 (1985) 397-411.
18. K. Gekko, Solution properties of polysaccharides, in: D.A. Brant (Ed.), ACS Symp. Ser. 150, American Chemical Society, Washington DC, 1981, pp. 415-438.
19. P.J. Flory and R. Rehner, Statistical mechanics of crosslinked polymer networks. II. Swelling, J. Chem. Phys. 11 (1943) 521-526.
20. N.A. Peppas and E.W. Merrill, Poly(vinyl alcohol) hydrogels: reinforcement of radiation-crosslinked networks by crystallization, J. Polym. Sci. Polym. Chem. 14 (1976) 441-457.
21. N. Errington, S.E. Harding, L. Illum and E.H. Schacht, Physico-chemical studies on diiodotyrosine dextran, Carbohydr. Polym. 18 (1992) 289-294.
22. D. Brown, Y.H. Bae and S.W. Kim, Hydrophilic solute release from a hydrophobic elastic matrix. Macromolecules 27 (1994) 4952-4959.
23. S.C. De Smedt, A. Lauwers, J. Demeester, M.J. van Steenbergen, W.E. Hennink and S.P.F.M. Roefs, Characterisation of the network structure of dextran glycidyl methacrylate hydrogels by studying the rheological and swelling behavior, Macromolecules 25 (1995) 5082-5088.
24. S.K. Patel, S. Malone, C. Cohen, J.R. Gillmor and R.H. Colby, Elastic modulus and equilibrium swelling of poly(dimethylsiloxane) networks, Macromolecules 25 (1992) 2541-5251.
25. A.E. Tonelli and E. Helfand, Elastically ineffective crosslinks in rubbers, Macromolecules 7 (1974) 59-63.
26. B.D. Barr-Howell and N.A. Peppas, Importance of junction functionality in highly crosslinked polymers, Polym. Bull. 13 (1985) 91-96.
27. C.T. Reinhart and N. Peppas, Solute diffusion in swollen membranes. Part II. Influence of crosslinking on diffusive properties, J. Membr. Sci. 18 (1984) 227-239.