Endothelial caveolae and caveolin-1 as key regulators of atherosclerosis

American Journal of Pathology

Volumn 177, Issue 2, 2010, Pages 544-546

  Frank, Philippe G ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ADIPOCYTE; ATHEROSCLEROSIS; CAVEOLA; CELL TYPE; CHOLESTEROL BLOOD LEVEL; DISEASE COURSE; ENDOTHELIUM; ENDOTHELIUM CELL; HOMEOSTASIS; INFLAMMATION; LIPOPROTEIN METABOLISM; MACROPHAGE; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER;

EID: 77957277805     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.100247     Document Type: Note

References (25)

1. Yamada E: The fine structure of the gall bladder epithelium of the mouse. J Biophys Biochem Cytol 1955, 1:445-458
2. Palade GE: Fine structure of blood capillaries. J Appl Physics 1953, 24:1424
3. Bruns RR, Palade GE: Studies on blood capillaries. II Transport of ferritin molecules across the wall of muscle capillaries. J Cell Biol 1968, 37:277-299
4. Bruns RR, Palade GE: Studies on blood capillaries. I General organization of blood capillaries in muscle, J Cell Biol 1968, 37:244-276
5. Kurzchalia TV, Dupree P, Monier S: VIP21-Caveolin, a protein of the trans-Golgi network and caveolae. FEBS Lett 1994, 346:88-91 (Pubitemid 2093461)
6. Frank PG, Lee H, Park DS, Tandon NN, Scherer PE, Lisanti MP: Genetic ablation of caveolin-1 confers protection against atherosclerosis. Arterioscler Thromb Vasc Biol 2004, 24:98-105 (Pubitemid 38082418)
7. Fernandez-Hernando C, Yu J, Suarez Y, Rahner C, Davalos A, Lasuncion MA, Sessa WC: Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis. Cell Metab 2009, 10:48-54
8. Frank PG, Lisanti MP: Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia. Curr Opin Lipidol 2004, 15:523-529
9. Williams TM, Lisanti MP: The Caveolin genes: from cell biology to medicine. Ann Med 2004, 36:584-595
10. Vasile E, Simionescu M, Simionescu N: Visualization of the binding, endocytosis, and transcytosis of low density lipoprotein in the arterial endothelium in situ. J Cell Biol 1983, 96:1677-1689 (Pubitemid 13034445)
11. Frank PG, Woodman SE, Park DS, Lisanti MP: Caveolin, caveolae, and endothelial cell function. Arterioscler Thromb Vasc Biol 2003, 23:1161-1168 (Pubitemid 36871269)
12. von Eckardstein A, Rohrer L: Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by lipoproteins. Curr Opin Lipidol 2009, 20:197-205
13. Wang XM, Kim HP, Song R, Choi AM: Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway. Am J Respir Cell Mol Biol 2006, 34:434-442
14. Frank PG, Cheung MW, Pavlides S, Llaverias G, Park DS, Lisanti MP: Caveolin-1 and regulation of cellular cholesterol homeostasis. Am J Physiol Heart Circ Physiol 2006, 291:H677-H686
15. Hassan GS, Jasmin JF, Schubert W, Frank PG, Lisanti MP: Caveolin-1 deficiency stimulates neointima formation during vascular injury. Biochemistry 2004, 43:8312-8321 (Pubitemid 38902511)
16. Schwencke C, Schmeisser A, Walter C, Wachter R, Pannach S, Weck B, Braun-Dullaeus RC, Kasper M, Strasser RH: Decreased caveolin-1 in atheroma: loss of antiproliferative control of vascular smooth muscle cells in atherosclerosis. Cardiovasc Res 2005, 68:128-135 (Pubitemid 41253563)
17. Fernandez-Hernando C, Yu J, Davalos A, Prendergast J, Sessa WC: Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol 2010, 177:998-1003
18. Milovanova T, Chatterjee S, Hawkins BJ, Hong N, Sorokina EM, Debolt K, Moore JS, Madesh M, Fisher AB: Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress. Biochim Biophys Acta 2008, 1783:1866-1875
19. D'Alessio A, Al-Lamki RS, Bradley JR, Pober JS: Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line. Am J Pathol 2005, 166:1273-1282 (Pubitemid 40524450)
20. Bouzin C, Brouet A, De Vriese J, Dewever J, Feron O: Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy. J Immunol 2007, 178:1505-1511 (Pubitemid 46154621)
21. Brouet A, Sonveaux P, Dessy C, Moniotte S, Balligand JL, Feron O: Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins. Circ Res 2001, 89:866-873 (Pubitemid 34627891)
22. Gargalovic P, Dory L: Cellular apoptosis is associated with increased caveolin-1 expression in macrophages. J Lipid Res 2003, 44:1622-1632 (Pubitemid 37185872)
23. Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA: Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension. FASEB J 2007, 21:2970-2979
24. Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J, Chien KR: Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci USA 2002, 99:11375-11380 (Pubitemid 34920933)
25. Jasmin JF, Mercier I, Dupuis J, Tanowitz HB, Lisanti MP: Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. Circulation 2006, 114:912-920 (Pubitemid 44337134)