-
1
-
-
0345798150
-
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
-
Abramsson A, Lindblom P, Betsholtz C. 2003. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest 112:1142-1151.
-
(2003)
J Clin Invest
, vol.112
, pp. 1142-1151
-
-
Abramsson, A.1
Lindblom, P.2
Betsholtz, C.3
-
2
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
Andrae J, Gallini R, Betsholtz C. 2008. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 22:1276-1312.
-
(2008)
Genes Dev
, vol.22
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
4
-
-
10544233369
-
Expression of plateletderived growth factor (PDGF)-A, PDGF-B and the PDGF-alpha receptor, but not the PDGF-beta receptor, in human malignant melanoma in vivo
-
Barnhill RL, Xiao M, Graves D, Antoniades HN. 1996. Expression of plateletderived growth factor (PDGF)-A, PDGF-B and the PDGF-alpha receptor, but not the PDGF-beta receptor, in human malignant melanoma in vivo. Br J Dermatol 135:898-904.
-
(1996)
Br J Dermatol
, vol.135
, pp. 898-904
-
-
Barnhill, R.L.1
Xiao, M.2
Graves, D.3
Antoniades, H.N.4
-
5
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. 2003. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 111:1287-1295.
-
(2003)
J Clin Invest
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
6
-
-
2942682933
-
Insight into the physiological functions of PDGF through genetic studies in mice
-
Betsholtz C. 2004. Insight into the physiological functions of PDGF through genetic studies in mice. Cytokine Growth Factor Rev 15:215-228.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 215-228
-
-
Betsholtz, C.1
-
8
-
-
34548150402
-
Angiogenesis and chronic inflammation: Cause or consequence?
-
Costa C, Incio J, Soares R. 2007. Angiogenesis and chronic inflammation: Cause or consequence? Angiogenesis 10:149-166.
-
(2007)
Angiogenesis
, vol.10
, pp. 149-166
-
-
Costa, C.1
Incio, J.2
Soares, R.3
-
9
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman J. 2007. Angiogenesis: An organizing principle for drug discovery? Nat Rev Drug Discov 6:273-286.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
10
-
-
58149463427
-
Initiation of oligodendrocyte progenitor cell migration by a PDGF-A activated extracellular regulated kinase (ERK) signaling pathway
-
Frost EE, Zhou Z, Krasnesky K, Armstrong RC. 2009. Initiation of oligodendrocyte progenitor cell migration by a PDGF-A activated extracellular regulated kinase (ERK) signaling pathway. Neurochem Res 34:169-181.
-
(2009)
Neurochem Res
, vol.34
, pp. 169-181
-
-
Frost, E.E.1
Zhou, Z.2
Krasnesky, K.3
Armstrong, R.C.4
-
11
-
-
16544382996
-
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate
-
Furuhashi M, Sjoblom T, Abramsson A, Ellingsen J, Micke P, Li H, Bergsten- Folestad E, Eriksson U, Heuchel R, Betsholtz C, Heldin CH, Ostman A. 2004. Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res 64:2725-2733.
-
(2004)
Cancer Res
, vol.64
, pp. 2725-2733
-
-
Furuhashi, M.1
Sjoblom, T.2
Abramsson, A.3
Ellingsen, J.4
Micke, P.5
Li, H.6
Bergsten-Folestad, E.7
Eriksson, U.8
Heuchel, R.9
Betsholtz, C.10
Heldin, C.H.11
Ostman, A.12
-
12
-
-
33751114201
-
Incidence, mortality and survival in cutaneous melanoma
-
Giblin AV, Thomas JM. 2007. Incidence, mortality and survival in cutaneous melanoma. J Plast Reconstr Aesthet Surg 60:32-40.
-
(2007)
J Plast Reconstr Aesthet Surg
, vol.60
, pp. 32-40
-
-
Giblin, A.V.1
Thomas, J.M.2
-
13
-
-
36249021985
-
Identification of a subset of pericytes that respond to combination therapy targeting PDGF and VEGF signaling
-
Hasumi Y, Klosowska-Wardega A, Furuhashi M, Ostman A, Heldin CH, Hellberg C. 2007. Identification of a subset of pericytes that respond to combination therapy targeting PDGF and VEGF signaling. Int J Cancer 121:2606-2614.
-
(2007)
Int J Cancer
, vol.121
, pp. 2606-2614
-
-
Hasumi, Y.1
Klosowska-Wardega, A.2
Furuhashi, M.3
Ostman, A.4
Heldin, C.H.5
Hellberg, C.6
-
14
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
Heldin CH, Westermark B. 1999. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79:1283-1316.
-
(1999)
Physiol Rev
, vol.79
, pp. 1283-1316
-
-
Heldin, C.H.1
Westermark, B.2
-
15
-
-
33645405597
-
Analysis of protein tyrosine kinases expression in the melanoma metastases of patients treated with Imatinib Mesylate (STI571, Gleevec)
-
Ivan D, Niveiro M, Diwan AH, Eton O, Kim KB, Lacey C, Gonzalez C, Prieto VG. 2006. Analysis of protein tyrosine kinases expression in the melanoma metastases of patients treated with Imatinib Mesylate (STI571, Gleevec). J Cutan Pathol 33:280-285.
-
(2006)
J Cutan Pathol
, vol.33
, pp. 280-285
-
-
Ivan, D.1
Niveiro, M.2
Diwan, A.H.3
Eton, O.4
Kim, K.B.5
Lacey, C.6
Gonzalez, C.7
Prieto, V.G.8
-
16
-
-
0346727319
-
What brings pericytes to tumor vessels?
-
Jain RK, Booth MF. 2003. What brings pericytes to tumor vessels? J Clin Invest 112:1134-1136.
-
(2003)
J Clin Invest
, vol.112
, pp. 1134-1136
-
-
Jain, R.K.1
Booth, M.F.2
-
17
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. 2008. Cancer statistics, 2008. CA Cancer J Clin 58:71-96.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
18
-
-
0026518279
-
Loss of c-kit expression in cultured melanoma cells
-
Lassam N, Bickford S. 1992. Loss of c-kit expression in cultured melanoma cells. Oncogene 7:51-56.
-
(1992)
Oncogene
, vol.7
, pp. 51-56
-
-
Lassam, N.1
Bickford, S.2
-
19
-
-
0342646934
-
Autocrine and paracrine regulation by cytokines and growth factors in melanoma
-
Lazar-Molnar E, Hegyesi H, Toth S, Falus A. 2000. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 12:547-554.
-
(2000)
Cytokine
, vol.12
, pp. 547-554
-
-
Lazar-Molnar, E.1
Hegyesi, H.2
Toth, S.3
Falus, A.4
-
20
-
-
33645505715
-
Chronotherapeutics: The relevance of timing in cancer therapy
-
Levi F. 2006. Chronotherapeutics: The relevance of timing in cancer therapy. Cancer Causes Control 17:611-621.
-
(2006)
Cancer Causes Control
, vol.17
, pp. 611-621
-
-
Levi, F.1
-
21
-
-
35148845723
-
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics
-
Levi F, Focan C, Karaboue A, de la Valette V, Focan-Henrard D, Baron B, Kreutz F, Giacchetti S. 2007. Implications of circadian clocks for the rhythmic delivery of cancer therapeutics. Adv Drug Deliv Rev 59:1015-1035.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1015-1035
-
-
Levi, F.1
Focan, C.2
Karaboue, A.3
De La Valette, V.4
Focan-Henrard, D.5
Baron, B.6
Kreutz, F.7
Giacchetti, S.8
-
22
-
-
33745889602
-
Antiproliferative effect of STI571 on cultured human cutaneous melanoma-derived cell lines
-
Mayorga ME, Sanchis D, Perez de Santos AM, Velasco A, Dolcet X, Casanova JM, Baradad M, Egido R, Pallares J, Espurz N, Benitez D, Mila J, Malvehy J, Castel T, Comella JX, Matias-Guiu X, Vilella R, Marti RM. 2006. Antiproliferative effect of STI571 on cultured human cutaneous melanoma-derived cell lines. Melanoma Res 16:127-135.
-
(2006)
Melanoma Res
, vol.16
, pp. 127-135
-
-
Mayorga, M.E.1
Sanchis, D.2
Perez De Santos, A.M.3
Velasco, A.4
Dolcet, X.5
Casanova, J.M.6
Baradad, M.7
Egido, R.8
Pallares, J.9
Espurz, N.10
Benitez, D.11
Mila, J.12
Malvehy, J.13
Castel, T.14
Comella, J.X.15
Matias-Guiu, X.16
Vilella, R.17
Marti, R.M.18
-
23
-
-
1442274594
-
Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo
-
McGary EC, Onn A, Mills L, Heimberger A, Eton O, Thomas GW, Shtivelband M, Bar-Eli M. 2004. Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo. J Invest Dermatol 122:400-405.
-
(2004)
J Invest Dermatol
, vol.122
, pp. 400-405
-
-
McGary, E.C.1
Onn, A.2
Mills, L.3
Heimberger, A.4
Eton, O.5
Thomas, G.W.6
Shtivelband, M.7
Bar-Eli, M.8
-
24
-
-
33750201262
-
Basis for dosing time-dependent change in the anti-tumor effect of imatinib in mice
-
Nakagawa H, Takiguchi T, Nakamura M, Furuyama A, Koyanagi S, Aramaki H, Higuchi S, Ohdo S. 2006. Basis for dosing time-dependent change in the anti-tumor effect of imatinib in mice. Biochem Pharmacol 72:1237-1245.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1237-1245
-
-
Nakagawa, H.1
Takiguchi, T.2
Nakamura, M.3
Furuyama, A.4
Koyanagi, S.5
Aramaki, H.6
Higuchi, S.7
Ohdo, S.8
-
25
-
-
48049100143
-
Improving chemotherapeutic drug penetration in melanoma by imatinib mesylate
-
Ogawa Y, Kawamura T, Furuhashi M, Tsukamoto K, Shimada S. 2008. Improving chemotherapeutic drug penetration in melanoma by imatinib mesylate. J Dermatol Sci 51:190-199.
-
(2008)
J Dermatol Sci
, vol.51
, pp. 190-199
-
-
Ogawa, Y.1
Kawamura, T.2
Furuhashi, M.3
Tsukamoto, K.4
Shimada, S.5
-
26
-
-
0035106940
-
Changing the dosing schedule minimizes the disruptive effects of interferon on clock function
-
Ohdo S, Koyanagi S, Suyama H, Higuchi S, Aramaki H. 2001. Changing the dosing schedule minimizes the disruptive effects of interferon on clock function. Nat Med 7:356-360.
-
(2001)
Nat Med
, vol.7
, pp. 356-360
-
-
Ohdo, S.1
Koyanagi, S.2
Suyama, H.3
Higuchi, S.4
Aramaki, H.5
-
27
-
-
2942670180
-
PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
-
Ostman A. 2004. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev 15:275-286.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 275-286
-
-
Ostman, A.1
-
28
-
-
0141486251
-
PDGF receptors as cancer drug targets
-
Pietras K, Sjoblom T, Rubin K, Heldin CH, Ostman A. 2003a. PDGF receptors as cancer drug targets. Cancer Cell 3:439-443.
-
(2003)
Cancer Cell
, vol.3
, pp. 439-443
-
-
Pietras, K.1
Sjoblom, T.2
Rubin, K.3
Heldin, C.H.4
Ostman, A.5
-
29
-
-
0141567995
-
STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake
-
Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, McSheehy P, Wartmann M, Ostman A. 2003b. STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake. Clin Cancer Res 9:3779-3787.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3779-3787
-
-
Pietras, K.1
Stumm, M.2
Hubert, M.3
Buchdunger, E.4
Rubin, K.5
Heldin, C.H.6
McSheehy, P.7
Wartmann, M.8
Ostman, A.9
-
31
-
-
35748951584
-
Anti-angiogenic effects of imatinib target smooth muscle cells but not endothelial cells
-
Rocha A, Azevedo I, Soares R. 2007. Anti-angiogenic effects of imatinib target smooth muscle cells but not endothelial cells. Angiogenesis 10:279-286.
-
(2007)
Angiogenesis
, vol.10
, pp. 279-286
-
-
Rocha, A.1
Azevedo, I.2
Soares, R.3
-
32
-
-
3242727861
-
STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells
-
Roussidis AE, Mitropoulou TN, Theocharis AD, Kiamouris C, Papadopoulos S, Kletsas D, Karamanos NK. 2004. STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells. Anticancer Res 24:1445-1447.
-
(2004)
Anticancer Res
, vol.24
, pp. 1445-1447
-
-
Roussidis, A.E.1
Mitropoulou, T.N.2
Theocharis, A.D.3
Kiamouris, C.4
Papadopoulos, S.5
Kletsas, D.6
Karamanos, N.K.7
-
33
-
-
34547637867
-
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
-
Sennino B, Falcon BL, McCauley D, Le T McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. 2007. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res 67:7358-7367.
-
(2007)
Cancer Res
, vol.67
, pp. 7358-7367
-
-
Sennino, B.1
Falcon, B.L.2
McCauley, D.3
Le, T.4
McCauley, T.5
Kurz, J.C.6
Haskell, A.7
Epstein, D.M.8
McDonald, D.M.9
-
34
-
-
0141958794
-
Analysis of protein tyrosine kinase expression in melanocytic lesions by tissue array
-
Shen SS, Zhang PS, Eton O, Prieto VG. 2003. Analysis of protein tyrosine kinase expression in melanocytic lesions by tissue array. J Cutan Pathol 30:539-547.
-
(2003)
J Cutan Pathol
, vol.30
, pp. 539-547
-
-
Shen, S.S.1
Zhang, P.S.2
Eton, O.3
Prieto, V.G.4
-
35
-
-
33845663074
-
Elucidating progesterone effects in breast cancer: Cross talk with PDGF signaling pathway in smooth muscle cell
-
Soares R, Guerreiro S, Botelho M. 2007. Elucidating progesterone effects in breast cancer: Cross talk with PDGF signaling pathway in smooth muscle cell. J Cell Biochem 100:174-183.
-
(2007)
J Cell Biochem
, vol.100
, pp. 174-183
-
-
Soares, R.1
Guerreiro, S.2
Botelho, M.3
-
36
-
-
38549173618
-
The effect of imatinib (Glivec) on scleroderma and normal dermal fibroblasts: A preclinical study
-
Soria A, Cario-Andre M, Lepreux S, Rezvani HR, Pasquet JM, Pain C, Schaeverbeke T, Mahon FX, Taieb A. 2008. The effect of imatinib (Glivec) on scleroderma and normal dermal fibroblasts: A preclinical study. Dermatology 216:109-117.
-
(2008)
Dermatology
, vol.216
, pp. 109-117
-
-
Soria, A.1
Cario-Andre, M.2
Lepreux, S.3
Rezvani, H.R.4
Pasquet, J.M.5
Pain, C.6
Schaeverbeke, T.7
Mahon, F.X.8
Taieb, A.9
-
38
-
-
34548580286
-
Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts
-
Vlahovic G, Ponce AM, Rabbani Z, Salahuddin FK, Zgonjanin L, Spasojevic I, Vujaskovic Z, Dewhirst MW. 2007. Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts. Br J Cancer 97:735-740.
-
(2007)
Br J Cancer
, vol.97
, pp. 735-740
-
-
Vlahovic, G.1
Ponce, A.M.2
Rabbani, Z.3
Salahuddin, F.K.4
Zgonjanin, L.5
Spasojevic, I.6
Vujaskovic, Z.7
Dewhirst, M.W.8
-
39
-
-
16644366418
-
Targeted therapy with imatinib: Hits and misses?
-
von Mehren M. 2005. Targeted therapy with imatinib: Hits and misses? J Clin Oncol 23:8-10.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8-10
-
-
Von Mehren, M.1
|