Production of anti-carbohydrate antibodies by phage display technologies: Potential impairment of cell growth as a result of endogenous expression

Journal of Biological Chemistry

Volumn 285, Issue 40, 2010, Pages 30587-30597

  Yuasa, Noriyuki ^a   Zhang, Wei ^a,c   Goto, Tomohiro ^a   Sakaue, Hiroyuki ^a   Matsumoto Takasaki, Ayano ^a   Kimura, Miyo ^a   Ohshima, Hiroya ^a   Tsuchida, Yasunobu ^a   Koizumi, Tomoyuki ^a   Sakai, Keiko ^a   Kojima, Takumi ^b   Yamamoto, Kazuo ^b   Nakata, Munehiro ^a   Fujita Yamaguchi, Yoko ^a  

^a TOKAI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Beijing Institute of Basic Medical Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOCHEMISTRY; CARBOHYDRATES; CELL GROWTH; CLONING; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH KINETICS; MAMMALS; PURIFICATION;

ANTI-CARBOHYDRATE ANTIBODIES; DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; ENDOGENOUS EXPRESSION; ENDOPLASMIC RETICULUM; EXTRACELLULAR; HUMAN IGG; INTRACELLULAR LOCALIZATION; LACTO-N-FUCOPENTAOSE III; MAMMALIAN CELLS; PHAGE CLONES; PHAGE DISPLAY TECHNOLOGY; PHAGE LIBRARIES; PROTEIN EXPRESSIONS; SINGLE CHAIN VARIABLE FRAGMENTS; STABLE CLONES; TRANSIENT EXPRESSION; TRANSLATED PROTEINS;

CLONE CELLS;

ANTIBODY; CARBOHYDRATE; CARBOHYDRATE ANTIBODY; DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; FC RECEPTOR; GLYCOLIPID; IMMUNOGLOBULIN G1; MANNOTRIOSE ANTIBODY; N FUCOPENTAOSE; N FUCOPENTAOSE ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; IMMUNOGLOBULIN G; MANNOTRIOSE; MONOCLONAL ANTIBODY; TRISACCHARIDE;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL GROWTH; CELL STRAIN COS7; CLONE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOPLASMIC RETICULUM; GENE CONSTRUCT; GENE EXPRESSION; GENE ISOLATION; GENE LIBRARY; GROWTH INHIBITION; MAMMAL CELL; MYELOMA CELL; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; PROTEIN SECRETION; ANIMAL; BIOSYNTHESIS; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; GENETICS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; TUMOR CELL LINE;

MAMMALIA;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN G; MICE; SINGLE-CHAIN ANTIBODIES; TRISACCHARIDES;

EID: 77957253270     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.107284     Document Type: Article

References (28)

1. Deng, S. J., MacKenzie, C. R., Sadowska, J., Michniewicz, J., Young, N. M., Bundle, D. R., and Narang, S. A. (1994) J. Biol. Chem. 269, 9533-9538
2. MacKenzie, C. R., Hirama, T., Deng, S. J., Bundle, D. R., Narang, S. A., and Young, N. M. (1996) J. Biol. Chem. 271, 1527-1533
3. van Kuppevelt, T. H., Dennissen, M. A., van Venrooij, W. J., Hoet, R. M., and Veerkamp, J. H. (1998) J. Biol. Chem. 273, 12960-12966
4. Mao, S., Gao, C., Lo, C. H., Wirsching, P., Wong, C. H., and Janda, K. D. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 6953-6958
5. Lee, K. J., Mao, S., Sun, C., Gao, C., Blixt, O., Arrues, S., Hom, L. G., Kaufmann, G. F., Hoffman, T. Z., Coyle, A. R., Paulson, J., Felding-Habermann, B., and Janda, K. D. (2002) J. Am. Chem. Soc. 124, 12439-12446
6. Ravn, P., Danielczyk, A., Jensen, K. B., Kristensen, P., Christensen, P. A., Larsen, M., Karsten, U., and Goletz, S. (2004) J. Mol. Biol. 343, 985-996
7. Sakai, K., Shimizu, Y., Chiba, T., Matsumoto-Takasaki, A., Kusada, Y., Zhang, W., Nakata, M., Kojima, N., Toma, K., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y. (2007) Biochemistry 46, 253-262
8. Zhang, W., Matsumoto-Takasaki, A., Kusada, Y., Sakaue, H., Sakai, K., Nakata, M., and Fujita-Yamaguchi, Y. (2007) Biochemistry 46, 263-270
9. Stoll, M. S., Mizuochi, T., Childs, R. A., and Feizi, T. (1988) Biochem. J. 256, 661-664
10. Shimizu, Y., Nakata, M., Matsunuma, J., and Mizuochi, T. (2001) J. Chromatogr. B. Biomed. Sci. Appl. 754, 127-133
11. Sblattero, D., and Bradbury, A. (2000) Nat. Biotechnol. 18, 75-80
12. Neumaier, M., Shively, L., Chen, F. S., Gaida, F. J., Ilgen, C., Paxton, R. J., Shively, J. E., and Riggs, A. D. (1990) Cancer Res. 50, 2128-2134
13. Wu, A. M., Chen, W., Raubitschek, A., Williams, L. E., Neumaier, M., Fischer, R., Hu, S. Z., Odom-Maryon, T., Wong, J. Y., and Shively, J. E. (1996) Immunotechnology 2, 21-36
14. Li, S. L., Liang, S. J., Guo, N., Wu, A. M., and Fujita-Yamaguchi, Y. (2000) Cancer Immunol. Immunother. 49, 243-252
15. Wu, A. M., Tan, G. J., Sherman, M. A., Clarke, P., Olafsen, T., Forman, S. J., and Raubitschek, A. A. (2001) Protein Eng. 14, 1025-1033
16. Ono, K., Kamihira, M., Kuga, Y., Matsumoto, H., Hotta, A., Itoh, T., Nishijima, K., Nakamura, N., Matsuda, H., and Iijima, S. (2003) J. Biosci. Bioeng. 95, 231-238
17. Ellgaard, L., and Helenius, A. (2003) Nat. Rev. Mol. Cell Biol. 4, 181-191
18. Haas, I. G. (1994) Experientia 50, 1012-1020
19. Gething, M. J. (1999) Semin. Cell Dev. Biol. 10, 465-472
20. Mintz, M., Vanderver, A., Brown, K. J., Lin, J., Wang, Z., Kaneski, C., Schiffmann, R., Nagaraju, K., Hoffman, E. P., and Hathout, Y. (2008) J. Proteome Res. 7, 2435-2444
21. Hosokawa, N., Wada, I., Hasegawa, K., Yorihuzi, T., Tremblay, L. O., Herscovics, A., and Nagata, K. (2001) EMBO Rep. 2, 415-422
22. Ye, J. J., Liang, S. J., Guo, N., Li, S. L., Wu, A. M., Giannini, S., Sachdev, D., Yee, D., Brünner, N., Ikle, D., and Fujita-Yamaguchi, Y. (2003) Horm. Metab. Res. 35, 836-842
23. Sachdev, D., Li, S. L., Hartell, J. S., Fujita-Yamaguchi, Y., Miller, J. S., and Yee, D. (2003) Cancer Res. 63, 627-635
24. Koda, Y., Kimura, H., and Mekada, E. (1993) Blood 9, 2915-2919
25. Gersten, K. M., Natsuka, S., Trinchera, M., Petryniak, B., Kelly, R. J., Hiraiwa, N., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Lowe, J. B. (1995) J. Biol. Chem. 270, 25047-25056
26. Fribley, A., Zhang, K., and Kaufman, R. J. (2009) Methods Mol. Biol. 559, 191-204
27. Umetsu, M., Tsumoto, K., Hara, M., Ashish, K., Goda, S., Adschiri, T., and Kumagai, I. (2003) J. Biol. Chem. 278, 8979-8987
28. Kabat, E. A., Wu, T. T., Perry, H., Gottesman, K., and Foeller, C. (1991) Sequences of Proteins of Immunological Interest, 5th Ed., Vol. I, pp. 103-140 and 310-324, National Institutes of Health Publication No. 91- 3242. National Institutes of Health, Bethesda