-
1
-
-
0036791348
-
How death shapes life during development
-
Baehrecke EH (2002) How death shapes life during development. Nat Rev Mol Cell Biol 3:779-787.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 779-787
-
-
Baehrecke, E.H.1
-
2
-
-
5044232018
-
Connecting proliferation and apoptosis in development and disease
-
DOI 10.1038/nrm1491
-
Hipfner DR, Cohen SM (2004) Connecting proliferation and apoptosis in development and disease. Nat Rev Mol Cell Biol 5:805-815. (Pubitemid 39336274)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.10
, pp. 805-815
-
-
Hipfner, D.R.1
Cohen, S.M.2
-
4
-
-
0017618537
-
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
-
Sulston JE, Horvitz HR (1977) Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol 56:110-156.
-
(1977)
Dev Biol
, vol.56
, pp. 110-156
-
-
Sulston, J.E.1
Horvitz, H.R.2
-
5
-
-
0042469295
-
Worms, life, and death (Nobel lecture)
-
Horvitz HR (2003) Worms, life, and death (Nobel lecture). ChemBioChem 4:697-711.
-
(2003)
ChemBioChem
, vol.4
, pp. 697-711
-
-
Horvitz, H.R.1
-
6
-
-
0033197540
-
The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein
-
Metzstein MM, Horvitz HR (1999) The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Mol Cell 4:309-319.
-
(1999)
Mol Cell
, vol.4
, pp. 309-319
-
-
Metzstein, M.M.1
Horvitz, H.R.2
-
7
-
-
0041827179
-
The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins
-
Thellmann M, Hatzold J, Conradt B (2003) The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins. Development 130:4057-4071.
-
(2003)
Development
, vol.130
, pp. 4057-4071
-
-
Thellmann, M.1
Hatzold, J.2
Conradt, B.3
-
8
-
-
0033529717
-
The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene
-
Conradt B, Horvitz HR (1999) The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene. Cell 98:317-327.
-
(1999)
Cell
, vol.98
, pp. 317-327
-
-
Conradt, B.1
Horvitz, H.R.2
-
9
-
-
33645094394
-
Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1
-
Liu H, Strauss TJ, Potts MB, Cameron S (2006) Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1. Development 133:641-650.
-
(2006)
Development
, vol.133
, pp. 641-650
-
-
Liu, H.1
Strauss, T.J.2
Potts, M.B.3
Cameron, S.4
-
10
-
-
67349124418
-
Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1
-
Potts MB, Wang DP, Cameron S (2009) Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1. Dev Biol 329:374-385.
-
(2009)
Dev Biol
, vol.329
, pp. 374-385
-
-
Potts, M.B.1
Wang, D.P.2
Cameron, S.3
-
11
-
-
34248180046
-
Timing of the onset of a development cell death is controlled by transciptional induction of the C. elegans ced-3 caspase-encoding gene
-
DOI 10.1242/dev.02818
-
Maurer CW, Chiorazzi M, Shaham S (2007) Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspase-encoding gene. Development 134:1357-1368. (Pubitemid 46706042)
-
(2007)
Development
, vol.134
, Issue.7
, pp. 1357-1368
-
-
Maurer, C.W.1
Chiorazzi, M.2
Shaham, S.3
-
12
-
-
27744547091
-
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
-
Wu WS, et al. (2005) Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 123:641-653.
-
(2005)
Cell
, vol.123
, pp. 641-653
-
-
Wu, W.S.1
-
13
-
-
0033197879
-
SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
-
Inukai T, et al. (1999) SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell 4:343-352.
-
(1999)
Mol Cell
, vol.4
, pp. 343-352
-
-
Inukai, T.1
-
14
-
-
35548973782
-
The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9
-
Schwartz HT, Horvitz HR (2007) The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9. Genes Dev 21:3181-3194.
-
(2007)
Genes Dev
, vol.21
, pp. 3181-3194
-
-
Schwartz, H.T.1
Horvitz, H.R.2
-
15
-
-
77954658825
-
Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons
-
Nehme R, et al. (2010) Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons. Cell Death Differ 17:1266-1276.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1266-1276
-
-
Nehme, R.1
-
16
-
-
0036638824
-
Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene
-
Li S, et al. (2002) Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development 129:3523-3532.
-
(2002)
Development
, vol.129
, pp. 3523-3532
-
-
Li, S.1
-
17
-
-
0023663870
-
A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant
-
Avery L, Horvitz HR (1987) A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant. Cell 51:1071-1078.
-
(1987)
Cell
, vol.51
, pp. 1071-1078
-
-
Avery, L.1
Horvitz, H.R.2
-
19
-
-
34347243197
-
A protocol describing pharynx counts and a review of other assays of apoptotic cell death in the nematode worm Caenorhabditis elegans
-
Schwartz HT (2007) A protocol describing pharynx counts and a review of other assays of apoptotic cell death in the nematode worm Caenorhabditis elegans. Nat Protoc 2:705-714.
-
(2007)
Nat Protoc
, vol.2
, pp. 705-714
-
-
Schwartz, H.T.1
-
20
-
-
0032524885
-
The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
-
Conradt B, Horvitz HR (1998) The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93:519-529.
-
(1998)
Cell
, vol.93
, pp. 519-529
-
-
Conradt, B.1
Horvitz, H.R.2
-
21
-
-
0033924215
-
Six family genes - Structure and function as transcription factors and their roles in development
-
Kawakami K, Sato S, Ozaki H, Ikeda K (2000) Six family genes - structure and function as transcription factors and their roles in development. Bioessays 22:616-626.
-
(2000)
Bioessays
, vol.22
, pp. 616-626
-
-
Kawakami, K.1
Sato, S.2
Ozaki, H.3
Ikeda, K.4
-
22
-
-
67549101891
-
A conserved Six-Eya cassette acts downstream of Wnt signaling to direct non-myogenic versus myogenic fates in the C. elegans postembryonic mesoderm
-
Amin NM, Lim SE, Shi H, Chan TL, Liu J (2009) A conserved Six-Eya cassette acts downstream of Wnt signaling to direct non-myogenic versus myogenic fates in the C. elegans postembryonic mesoderm. Dev Biol 331:350-360.
-
(2009)
Dev Biol
, vol.331
, pp. 350-360
-
-
Amin, N.M.1
Lim, S.E.2
Shi, H.3
Chan, T.L.4
Liu, J.5
-
23
-
-
0028244770
-
The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system
-
Cheyette BN, et al. (1994) The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron 12:977-996.
-
(1994)
Neuron
, vol.12
, pp. 977-996
-
-
Cheyette, B.N.1
-
24
-
-
34548657817
-
The eyes absent family of phosphotyrosine phosphatases: Properties and roles in developmental regulation of transcription
-
Jemc J, Rebay I (2007) The eyes absent family of phosphotyrosine phosphatases: Properties and roles in developmental regulation of transcription. Annu Rev Biochem 76:513-538.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 513-538
-
-
Jemc, J.1
Rebay, I.2
-
25
-
-
0031444287
-
The eye-specification proteins so and Eya form a complex and regulate multiple steps in Drosophila eye development
-
DOI 10.1016/S0092-8674(00)80480-8
-
Pignoni F, et al. (1997) The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development. Cell 91:881-891. (Pubitemid 28027823)
-
(1997)
Cell
, vol.91
, Issue.7
, pp. 881-891
-
-
Pignoni, F.1
Hu, B.2
Zavitz, K.H.3
Xiao, J.4
Garrity, P.A.5
Zipursky, S.L.6
-
26
-
-
0033573003
-
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
-
Heanue TA, et al. (1999) Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation. Genes Dev 13:3231-3243.
-
(1999)
Genes Dev
, vol.13
, pp. 3231-3243
-
-
Heanue, T.A.1
-
27
-
-
26644431590
-
The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6
-
Furuya M, Qadota H, Chisholm AD, Sugimoto A (2005) The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6. Dev Biol 286:452-463.
-
(2005)
Dev Biol
, vol.286
, pp. 452-463
-
-
Furuya, M.1
Qadota, H.2
Chisholm, A.D.3
Sugimoto, A.4
-
28
-
-
21644477891
-
Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog
-
Pauli T, Seimiya M, Blanco J, Gehring WJ (2005) Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog. Development 132:2771-2782.
-
(2005)
Development
, vol.132
, pp. 2771-2782
-
-
Pauli, T.1
Seimiya, M.2
Blanco, J.3
Gehring, W.J.4
-
29
-
-
0036479097
-
Misexpression of the eyes absent family triggers the apoptotic program
-
Clark SW, Fee BE, Cleveland JL (2002) Misexpression of the eyes absent family triggers the apoptotic program. J Biol Chem 277:3560-3567.
-
(2002)
J Biol Chem
, vol.277
, pp. 3560-3567
-
-
Clark, S.W.1
Fee, B.E.2
Cleveland, J.L.3
-
30
-
-
0027510673
-
The eyes absent gene: Genetic control of cell survival and differentiation in the developing Drosophila eye
-
Bonini NM, Leiserson WM, Benzer S (1993) The eyes absent gene: Genetic control of cell survival and differentiation in the developing Drosophila eye. Cell 72:379-395.
-
(1993)
Cell
, vol.72
, pp. 379-395
-
-
Bonini, N.M.1
Leiserson, W.M.2
Benzer, S.3
-
31
-
-
9744281187
-
The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line
-
Kozlowski DJ, Whitfield TT, Hukriede NA, Lam WK, Weinberg ES (2005) The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line. Dev Biol 277:27-41.
-
(2005)
Dev Biol
, vol.277
, pp. 27-41
-
-
Kozlowski, D.J.1
Whitfield, T.T.2
Hukriede, N.A.3
Lam, W.K.4
Weinberg, E.S.5
-
32
-
-
0032842838
-
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
-
Xu PX, et al. (1999) Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet 23:113-117.
-
(1999)
Nat Genet
, vol.23
, pp. 113-117
-
-
Xu, P.X.1
-
33
-
-
0344875035
-
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis
-
Li X, et al. (2003) Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature 426:247-254.
-
(2003)
Nature
, vol.426
, pp. 247-254
-
-
Li, X.1
-
34
-
-
63849187827
-
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
-
Cook PJ, et al. (2009) Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458:591-596.
-
(2009)
Nature
, vol.458
, pp. 591-596
-
-
Cook, P.J.1
-
35
-
-
13444252265
-
Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth
-
Zhang L, et al. (2005) Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth. Cancer Res 65:925-932.
-
(2005)
Cancer Res
, vol.65
, pp. 925-932
-
-
Zhang, L.1
-
36
-
-
0032514597
-
Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis
-
Ford HL, Kabingu EN, Bump EA, Mutter GL, Pardee AB (1998) Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis. Proc Natl Acad Sci USA 95:12608-12613.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12608-12613
-
-
Ford, H.L.1
Kabingu, E.N.2
Bump, E.A.3
Mutter, G.L.4
Pardee, A.B.5
-
37
-
-
20144387707
-
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss
-
Schönberger J, et al. (2005) Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nat Genet 37:418-422.
-
(2005)
Nat Genet
, vol.37
, pp. 418-422
-
-
Schönberger, J.1
-
38
-
-
0033064156
-
Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly
-
Wallis DE, et al. (1999) Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly. Nat Genet 22:196-198.
-
(1999)
Nat Genet
, vol.22
, pp. 196-198
-
-
Wallis, D.E.1
-
39
-
-
0031046284
-
A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family
-
Abdelhak S, et al. (1997) A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family. Nat Genet 15:157-164.
-
(1997)
Nat Genet
, vol.15
, pp. 157-164
-
-
Abdelhak, S.1
-
40
-
-
2542620650
-
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes
-
Ruf RG, et al. (2004) SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. Proc Natl Acad Sci USA 101:8090-8095.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8090-8095
-
-
Ruf, R.G.1
-
41
-
-
48549091913
-
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly
-
Geng X, et al. (2008) Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell 15:236-247.
-
(2008)
Dev Cell
, vol.15
, pp. 236-247
-
-
Geng, X.1
-
42
-
-
0041326752
-
The role of Six1 in mammalian auditory system development
-
DOI 10.1242/dev.00628
-
Zheng W, et al. (2003) The role of Six1 in mammalian auditory system development. Development 130:3989-4000. (Pubitemid 37063418)
-
(2003)
Development
, vol.130
, Issue.17
, pp. 3989-4000
-
-
Zheng, W.1
Huang, L.2
Wei, Z.-B.3
Silvius, D.4
Tang, B.5
Xu, P.-X.6
-
43
-
-
0041853845
-
Six1 is required for the early organogenesis of mammalian kidney
-
Xu PX, et al. (2003) Six1 is required for the early organogenesis of mammalian kidney. Development 130:3085-3094.
-
(2003)
Development
, vol.130
, pp. 3085-3094
-
-
Xu, P.X.1
-
44
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
|