메뉴 건너뛰기




Volumn 70, Issue 2, 2010, Pages 227-231

Can autism be triggered by acetaminophen activation of the endocannabinoid system?

Author keywords

Acetaminophen; Autism; Autistic disorder; Cannabinoid receptors; Endocannabinoid system

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; PARACETAMOL;

EID: 77957234850     PISSN: 00651400     EISSN: 00651400     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (40)

References (53)
  • 1
    • 0032785673 scopus 로고    scopus 로고
    • Sulphation deficit in "low-functioning" autistic children: A pilot study
    • Alberti A, Pirrone P, Elia M, Waring RH, Romano C (1999) Sulphation deficit in "low-functioning" autistic children: a pilot study. Biol Psychiatry 46: 420-424.
    • (1999) Biol Psychiatry , vol.46 , pp. 420-424
    • Alberti, A.1    Pirrone, P.2    Elia, M.3    Waring, R.H.4    Romano, C.5
  • 2
    • 0004235298 scopus 로고
    • American Psychiatric Association, 4th ed.). American Psychiatric Association, Washington, DC
    • American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th ed.). American Psychiatric Association, Washington, DC.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 70349706250 scopus 로고    scopus 로고
    • The polarized life of the endocannabinoid system in CNS development
    • Anavi-Goffer S, Mulder J (2009) The polarized life of the endocannabinoid system in CNS development. Chembiochem 10: 1591-1598.
    • (2009) Chembiochem , vol.10 , pp. 1591-1598
    • Anavi-Goffer, S.1    Mulder, J.2
  • 4
    • 8844277748 scopus 로고    scopus 로고
    • Is autism an autoimmune disease?
    • Ashwood P, Van de Water J (2004) Is autism an autoimmune disease? Autoimmun Rev 3: 557-562.
    • (2004) Autoimmun Rev , vol.3 , pp. 557-562
    • Ashwood, P.1    Water, J.V.D.2
  • 5
    • 33751581761 scopus 로고    scopus 로고
    • The immune response in autism: A new frontier for autism research
    • Ashwood P, Wills S, Van de Water J (2006) The immune response in autism: a new frontier for autism research. J Leukoc Biol 80: 1-15.
    • (2006) J Leukoc Biol , vol.80 , pp. 1-15
    • Ashwood, P.1    Wills, S.2    Water, J.V.D.3
  • 6
    • 14644395605 scopus 로고    scopus 로고
    • Neuroanatomic observations of the brain in autism: A review and future directions
    • Bauman ML, Kemper TL (2005) Neuroanatomic observations of the brain in autism: a review and future directions. Int J Dev Neurosci 23: 183-187.
    • (2005) Int J Dev Neurosci , vol.23 , pp. 183-187
    • Bauman, M.L.1    Kemper, T.L.2
  • 7
    • 70549097126 scopus 로고    scopus 로고
    • Similarities in features of autism and asthma and a possible link to acetaminophen use
    • Becker KG, Schultz ST (2009) Similarities in features of autism and asthma and a possible link to acetaminophen use. Med Hypotheses 74: 7-11.
    • (2009) Med Hypotheses , vol.74 , pp. 7-11
    • Becker, K.G.1    Schultz, S.T.2
  • 9
    • 67650074647 scopus 로고    scopus 로고
    • Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations
    • Campolongo P, Trezza V, Palmery M, Trabace L, Cuomo V (2009) Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations. Int Rev Neurobiol 85: 117-133.
    • (2009) Int Rev Neurobiol , vol.85 , pp. 117-133
    • Campolongo, P.1    Trezza, V.2    Palmery, M.3    Trabace, L.4    Cuomo, V.5
  • 10
    • 84876241065 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, 11th ed.). Centers for Disease Control and Prevention, Atlanta, GA
    • Centers for Disease Control and Prevention (2009) Epidemiology and Prevention of Vaccine-Preventible Diseases (11th ed.). Centers for Disease Control and Prevention, Atlanta, GA.
    • (2009) Epidemiology and Prevention of Vaccine-Preventible Diseases
  • 11
    • 2342419981 scopus 로고    scopus 로고
    • No evidence for links between autism, MMR and measles virus
    • Chen W, Landau S, Sham P, Fombonne E (2004) No evidence for links between autism, MMR and measles virus. Psychol Med 34: 543-553.
    • (2004) Psychol Med , vol.34 , pp. 543-553
    • Chen, W.1    Landau, S.2    Sham, P.3    Fombonne, E.4
  • 12
    • 33645232376 scopus 로고    scopus 로고
    • Immunological findings in autism
    • Cohly HH, Panja A (2005) Immunological findings in autism. Int Rev Neurobiol 71: 317-341.
    • (2005) Int Rev Neurobiol , vol.71 , pp. 317-341
    • Cohly, H.H.1    Panja, A.2
  • 13
    • 0033510928 scopus 로고    scopus 로고
    • Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders
    • Connolly AM, Chez MG, Pestronk A, Arnold ST, Mehta S, Deuel RK (1999) Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders. J Pediatr 134: 607-613.
    • (1999) J Pediatr , vol.134 , pp. 607-613
    • Connolly, A.M.1    Chez, M.G.2    Pestronk, A.3    Arnold, S.T.4    Mehta, S.5    Deuel, R.K.6
  • 14
    • 0022420348 scopus 로고
    • Fever in autistics
    • Cotterill RM (1985) Fever in autistics. Nature 313: 426.
    • (1985) Nature , vol.313 , pp. 426
    • Cotterill, R.M.1
  • 18
    • 0035819919 scopus 로고    scopus 로고
    • Time trends in autism and MMR immunization coverage in California
    • Dales L, Hammer SJ, Smith NJ (2001) Time trends in autism and MMR immunization coverage in California. JAMA 285: 1183-1185.
    • (2001) JAMA , vol.285 , pp. 1183-1185
    • Dales, L.1    Hammer, S.J.2    Smith, N.J.3
  • 19
    • 0003641738 scopus 로고    scopus 로고
    • Department of Developmental Services, California Health and Human Services Agency, A Report to the Legislature March 1, 1999. California Health and Human Services Agency, Sacramento, CA, Available at
    • Department of Developmental Services, California Health and Human Services Agency (1999) Changes in the population of persons with autism and pervasive developmental disorders in California's Developmental Services System: 1987 through 1998. A Report to the Legislature March 1, 1999. California Health and Human Services Agency, Sacramento, CA. [Available at: http://www.dds.ca.gov/Autism/docs/autism_report_1999.pdf].
    • (1999) Changes In the Population of Persons With Autism and Pervasive Developmental Disorders In California's Developmental Services System: 1987 Through 1998
  • 20
    • 0345255894 scopus 로고    scopus 로고
    • Cannabinoids: Mechanisms and therapeutic applications in the CNS
    • Drysdale AJ, Platt B (2003) Cannabinoids: mechanisms and therapeutic applications in the CNS. Curr Med Chem 10: 2719-2732.
    • (2003) Curr Med Chem , vol.10 , pp. 2719-2732
    • Drysdale, A.J.1    Platt, B.2
  • 21
    • 71749094505 scopus 로고    scopus 로고
    • Differential monocyte responses to TLR ligands in children with autism spectrum disorders
    • Entstrom AM, Onore CE, Van de Water JA, Ashwood P (2010) Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain Behav Immun 24: 64-71.
    • (2010) Brain Behav Immun , vol.24 , pp. 64-71
    • Entstrom, A.M.1    Onore, C.E.2    Water, J.A.V.D.3    Ashwood, P.4
  • 22
    • 0141427915 scopus 로고    scopus 로고
    • Epidemiological surveys of autism and other pervasive developmental disorders: An update
    • Fombonne E (2003) Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord 33: 365-382.
    • (2003) J Autism Dev Disord , vol.33 , pp. 365-382
    • Fombonne, E.1
  • 23
    • 70350346857 scopus 로고    scopus 로고
    • Endogenous cannabinoids induce fever through the activation of CB1 receptors
    • Fraga D, Zanoni CI, Rae GA, Prada CA, Souza GE (2009) Endogenous cannabinoids induce fever through the activation of CB1 receptors. Br J Pharmacol 157: 1494-1501.
    • (2009) Br J Pharmacol , vol.157 , pp. 1494-1501
    • Fraga, D.1    Zanoni, C.I.2    Rae, G.A.3    Prada, C.A.4    Souza, G.E.5
  • 24
    • 67651183651 scopus 로고    scopus 로고
    • The endocannabinoid system during development: Emphasis on Perinatal events and delayed effects
    • Fride E, Gobshtis FE, Dahan H, Weller A, Giuffrida A, Ben-Shabat S (2009) The endocannabinoid system during development: emphasis on Perinatal events and delayed effects. Vitam Horm 81: 139-158.
    • (2009) Vitam Horm , vol.81 , pp. 139-158
    • Fride, E.1    Gobshtis, F.E.2    Dahan, H.3    Weller, A.4    Giuffrida, A.5    Ben-Shabat, S.6
  • 26
    • 54049144180 scopus 로고    scopus 로고
    • Wiring and firing neuronal networks: Endocannabinoids take center stage
    • Harkany T, Mackie K, Doherty P (2008) Wiring and firing neuronal networks: endocannabinoids take center stage. Cur Opin Neurobiol 18: 338-345.
    • (2008) Cur Opin Neurobiol , vol.18 , pp. 338-345
    • Harkany, T.1    Mackie, K.2    Doherty, P.3
  • 27
    • 24744469860 scopus 로고    scopus 로고
    • Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydro-lase-dependent arachidonic acid conjugation in the nervous system
    • Högestätt ED, Jönsson BA, Ermund A, Andersson DA, Björk H, Alexander JP, Cravatt BF, Basbaum AI, Zygmunt PM (2005) Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydro-lase-dependent arachidonic acid conjugation in the nervous system. J Biol Chem 280: 31405-31412.
    • (2005) J Biol Chem , vol.280 , pp. 31405-31412
    • Högestätt, E.D.1    Jönsson, B.A.2    Ermund, A.3    Andersson, D.A.4    Björk, H.5    Alexander, J.P.6    Cravatt, B.F.7    Basbaum, A.I.8    Zygmunt, P.M.9
  • 28
    • 69249226356 scopus 로고    scopus 로고
    • Long-term consequences of adolescent cannabis exposure on the development of cognition, brain structure and function: An overview of animal and human research
    • Jager G, Ramsey NF (2008) Long-term consequences of adolescent cannabis exposure on the development of cognition, brain structure and function: an overview of animal and human research. Curr Drug Abuse Rev 1: 114-123.
    • (2008) Curr Drug Abuse Rev , vol.1 , pp. 114-123
    • Jager, G.1    Ramsey, N.F.2
  • 29
    • 17144419260 scopus 로고    scopus 로고
    • Dysregulated innate immune responses in young children with autism spectrum disorders: Their relationship to gastrointestinal symptoms and dietary intervention
    • Jyonouchi H, Geng L, Ruby A, Zimmerman-Bier B (2005) Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention. Neuropsychobiology 51: 77-85.
    • (2005) Neuropsychobiology , vol.51 , pp. 77-85
    • Jyonouchi, H.1    Geng, L.2    Ruby, A.3    Zimmerman-Bier, B.4
  • 30
    • 0034071805 scopus 로고    scopus 로고
    • Detection and sequencing of measles virus from peripheral mononuclear cells from patients with inflammatory bowel disease and autism
    • Kawashima H, Mori T, Kashiwagi Y, Takekuma K, Hoshika A, Wakefield A (2000) Detection and sequencing of measles virus from peripheral mononuclear cells from patients with inflammatory bowel disease and autism. Dig Dis Sci 45: 723-729.
    • (2000) Dig Dis Sci , vol.45 , pp. 723-729
    • Kawashima, H.1    Mori, T.2    Kashiwagi, Y.3    Takekuma, K.4    Hoshika, A.5    Wakefield, A.6
  • 31
    • 38449116336 scopus 로고    scopus 로고
    • Possible immunological disorders in autism: Concomitant autoim-munity and immune tolerance
    • Kawashti MI, Amin OR, Rowehy NG (2006) Possible immunological disorders in autism: concomitant autoim-munity and immune tolerance. Egypt J Immunol 13: 99-104.
    • (2006) Egypt J Immunol , vol.13 , pp. 99-104
    • Kawashti, M.I.1    Amin, O.R.2    Rowehy, N.G.3
  • 38
    • 0032474231 scopus 로고    scopus 로고
    • No evidence for measles, mumps, and rubella vaccine-associated inflammatory bowel disease or autism in a 14-year prospective study
    • Peltola H, Patja A, Leinikki P, Valle M, Davidkin I, Paunio M (1998) No evidence for measles, mumps, and rubella vaccine-associated inflammatory bowel disease or autism in a 14-year prospective study. Lancet 351: 1327-1328.
    • (1998) Lancet , vol.351 , pp. 1327-1328
    • Peltola, H.1    Patja, A.2    Leinikki, P.3    Valle, M.4    Davidkin, I.5    Paunio, M.6
  • 42
    • 41949092859 scopus 로고    scopus 로고
    • Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: The results of a parent survey
    • Schultz ST, Klonoff-Cohen HS, Wingard DL, Akshoomoff NA, Macera CA, Ji M (2008) Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. Autism 12: 293-307.
    • (2008) Autism , vol.12 , pp. 293-307
    • Schultz, S.T.1    Klonoff-Cohen, H.S.2    Wingard, D.L.3    Akshoomoff, N.A.4    Macera, C.A.5    Ji, M.6
  • 44
    • 0036653257 scopus 로고    scopus 로고
    • Abnormal measles-mumps-rubella antibodies and CNS autoim-munity in children with autism
    • Singh VK, Lin SX, Newell E, Nelson C (2002) Abnormal measles-mumps-rubella antibodies and CNS autoim-munity in children with autism. J Biomed Sci 9: 359-364.
    • (2002) J Biomed Sci , vol.9 , pp. 359-364
    • Singh, V.K.1    Lin, S.X.2    Newell, E.3    Nelson, C.4
  • 45
    • 0038351887 scopus 로고    scopus 로고
    • Elevated levels of measles antibodies in children with autism
    • Singh VK, Jensen RL (2003) Elevated levels of measles antibodies in children with autism. Pediatr Neurol 28: 292-294.
    • (2003) Pediatr Neurol , vol.28 , pp. 292-294
    • Singh, V.K.1    Jensen, R.L.2
  • 46
    • 0018888677 scopus 로고
    • Why do autistic children?
    • Sullivan RC (1980) Why do autistic children? J Autism Dev Disord 10: 231-241.
    • (1980) J Autism Dev Disord , vol.10 , pp. 231-241
    • Sullivan, R.C.1
  • 47
    • 0033549334 scopus 로고    scopus 로고
    • Autism and measles, mumps, and rubella vaccine: No epidemiological evidence for a causal association
    • Taylor B, Miller E, Farrington P, Petropoulos MC, Favot-Mayaud I, Li J, Waight PA (1999) Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 353: 2026-2029.
    • (1999) Lancet , vol.353 , pp. 2026-2029
    • Taylor, B.1    Miller, E.2    Farrington, P.3    Petropoulos, M.C.4    Favot-Mayaud, I.5    Li, J.6    Waight, P.A.7
  • 48
    • 67651121672 scopus 로고    scopus 로고
    • The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages
    • Tolon RM, Nunez E, Pazos MR, Benito C, Castillo AI, Martínez-Orgado JA, Romero J (2009) The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. Brain Res 1283: 148-154.
    • (2009) Brain Res , vol.1283 , pp. 148-154
    • Tolon, R.M.1    Nunez, E.2    Pazos, M.R.3    Benito, C.4    Castillo, A.I.5    Martínez-Orgado, J.A.6    Romero, J.7
  • 49
    • 2642541787 scopus 로고    scopus 로고
    • Is fever suppression involved in the etiology of autism and neurodevelopmental disorders?
    • Torres AR (2003) Is fever suppression involved in the etiology of autism and neurodevelopmental disorders? BMC Pediatrics 3: 9.
    • (2003) BMC Pediatrics , vol.3 , pp. 9
    • Torres, A.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.