Dual effect of nitric oxide on uterine prostaglandin synthesis in a murine model of preterm labour

British Journal of Pharmacology

Volumn 161, Issue 4, 2010, Pages 844-855

  Cella, M ^a   Farina, M G ^a   Dominguez Rubio, A P ^a   Di Girolamo, G ^a   Ribeiro, M L ^a   Franchi, A M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

nitric oxide; preterm delivery; prostaglandins; uterus

Indexed keywords

AMINOGUANIDINE; ARGININE; CARBON 14; CITRULLINE; CYCLOOXYGENASE 2 INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; MELOXICAM; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; MOUSE; NONHUMAN; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RADIOACTIVITY; RADIOIMMUNOASSAY; REPEATED DRUG DOSE; UTERUS; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CYCLOOXYGENASE 2 INHIBITORS; DINOPROST; DINOPROSTONE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; GUANIDINES; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OBSTETRIC LABOR, PREMATURE; PREGNANCY; RADIOIMMUNOASSAY; THIAZINES; THIAZOLES; UTERUS;

EID: 77957225932     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00911.x     Document Type: Article

References (47)

1. Aisemberg J, Vercelli C, Billi S, Ribeiro ML, Ogando D, Meiss R et al. (2007). Nitric oxide mediates prostaglandins' deleterious effect on lipopolysaccharide-triggered murine fetal resorption. Proc Natl Acad Sci USA 104 : 7534 7539. (Pubitemid 47185941)
2. Alexander SP, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd edition. Br J Pharmacol 153 (Suppl. 2 S1 S209. (Pubitemid 351415518)
3. Anbe H, Okawa T, Sugawara N, Takahashi H, Sato A, Vedernikov YP et al. (2007). Influence of progesterone on myometrial contractility in pregnant mice treated with lipopolysaccharide. J Obstet Gynaecol Res 33 : 765 771. (Pubitemid 350086506)
4. Baggia S, Gravett MG, Witkin SS, Haluska GJ, Novy MJ (1996). Interleukin-1 beta intra-amniotic infusion induces tumor necrosis factor-alpha, prostaglandin production, and preterm contractions in pregnant rhesus monkeys. J Soc Gynecol Investig 3 : 121 126. (Pubitemid 26139460)
5. Bradford M (1976). A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 : 248 254.
6. Bredt DS, Snyder SH (1989). Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86 : 9030 9033.
7. Cella M, Aisemberg J, Sordelli MS, Billi S, Farina M, Franchi AM et al. (2006). Prostaglandins modulate nitric oxide synthase activity early in time in the uterus of estrogenized rat challenged with lipopolysaccharide. Eur J Pharmacol 534 : 218 226. (Pubitemid 43384204)
8. Dong YL, Gangula PR, Yallampalli C (1996). Nitric oxide synthase isoforms in the rat uterus: differential regulation during pregnancy and labor. J Reprod Fertil 107 : 249 254. (Pubitemid 126686999)
9. Farina M, Ribeiro ML, Ogando D, Gimeno M, Franchi AM (2000). IL1alpha augments prostaglandin synthesis in pregnant rat uteri by a nitric oxide mediated mechanism. Prostaglandins Leukot Essent Fatty Acids 62 : 243 247. (Pubitemid 30410530)
10. Farina M, Ribeiro ML, Franchi A (2001). Nitric oxide synthases in pregnant rat uterus. Reproduction 121 : 403 407. (Pubitemid 32243684)
11. Farina M, Ribeiro ML, Weissmann C, Estevez A, Billi S, Vercelli C et al. (2004). Biosynthesis and catabolism of prostaglandin F2alpha (PGF2alpha) are controlled by progesterone in the rat uterus during pregnancy. J Steroid Biochem Mol Biol 91 : 211 218. (Pubitemid 39164604)
12. Fetalvero KM, Zhang P, Shyu M, Young BT, Hwa J, Young RC et al. (2008). Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition. J Clin Invest 118 : 3966 3979.
13. Fidel PL, Romero R, Wolf N, Cutright J, Ramirez M, Araneda H et al. (1994). Systemic and local cytokine profiles in endotoxin-induced preterm parturition in mice. Am J Obstet Gynecol 170 : 1467 1475. (Pubitemid 24188728)
14. Franchi AM, Chaud M, Rettori V, Suburo A, McCann SM, Gimeno M (1994). Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uteri. Proc Natl Acad Sci USA 91 : 539 543. (Pubitemid 24041437)
15. Gross G, Imamura T, Vogt SK, Wozniak DF, Nelson DM, Sadovsky Y et al. (2000). Inhibition of cyclooxygenase-2 prevents inflammation-mediated preterm labor in the mouse. Am J Physiol Regul Integr Comp Physiol 278 : R1415 R1423. (Pubitemid 30439260)
16. Hamrick TS, Horton JR, Spears PA, Havell EA, Smoak IW, Orndorff PE (2003). Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastrically. Infect Immun 71 : 5202 5209.
17. Hsu CD, Meaddough E, Aversa K, Hong SF, Lee IS, Bahodo-Singh RO et al. (1998). Dual roles of amniotic fluid nitric oxide and PGE2 in preterm labor with intra-amniotic infection. Am J Perinatol 15 : 683 687. (Pubitemid 29191159)
18. Kaga N, Katsuki Y, Kajikawa S, Shibutani Y (1997). Preventive effect of ritodrine hydrochloride and/or urinary trypsin inhibitor against lipopolysaccharide-induced preterm delivery in mice. Acta Obstet Gynecol Scand 76 : 811 816. (Pubitemid 27429873)
19. 2+ concentration and insulin secretion in rat pancreatic beta β-cells. Am J Physiol Cell Physiol 284 : C1215 C1222. (Pubitemid 36457402)
20. Keelan A, Blumenstein M, Helliwell RJ, Sato TA, Marvin KW, Mitchell MD (2003). Cytokines, prostaglandins and parturition - a review. Placenta 24 (Suppl. A S33 S46. (Pubitemid 37184733)
21. Kelly RW (2002). Inflammatory mediators and cervical ripening. J Reprod Immunol 57 : 217 224.
22. Kenneth K (1994). Inducible cyclooxigenase and nitric oxide synthase. Adv Pharmacol 33 : 179 198.
23. Lamont RF, Duncan SL, Mandal D, Bassett P (2003). Intravaginal clindamycin to reduce preterm birth in women with abnormal genital tract flora. Obstet Gynecol 101 : 516 522. (Pubitemid 36288492)
24. Lee SK, Kim HS, Lee HJ, Lee J, Jeon BH, Jun CD et al. (2006). Dual effect of nitric oxide in immortalized and malignant human oral keratinocytes: induction of apoptosis and differentiation. J Oral Pathol Med 35 : 352 360. (Pubitemid 43876219)
25. Liew FY (1995). Regulation of lymphocyte functions by nitric oxide. Curr Opin Immunol 7 : 396 399.
26. Liu RH, Hotchkiss JH (1995). Potential genotoxicity of chronically elevated nitric oxide; a review. Mutat Res 339 : 73 89.
27. Mac Micking J, Xie QW, Nathan C (1997). Nitric oxide and macrophage function. Annu Rev Immunol 15 : 323 350. (Pubitemid 27169284)
28. Mitchell BF, Taggart MJ (2009). Are animal models relevant to key aspects of human parturition? Am J Physiol Regul Integr Comp Physiol 297 : R525 R545.
29. Nakaya Y, Yamamoto S, Hamada Y, Kamada M, Aono T, Niwa M (1996). Inducible nitric oxide synthase in uterine smooth muscle. Life Sci 58 : PL249 PL255. (Pubitemid 26086424)
30. Ogando D, Farina M, Ribeiro ML, Perez Martinez S, Cella M, Rettori V et al. (2003a). Steroid hormones augment nitric oxide synthase activity and expression in rat uterus. Reprod Fertil Dev 15 : 269 274. (Pubitemid 38139737)
31. Ogando DG, Paz D, Cella M, Franchi AM (2003b). The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice. Reproduction 125 : 95 110. (Pubitemid 36231214)
32. Olson DM, Ammann C (2007). Role of the prostaglandins in labour and prostaglandin receptor inhibitors in the prevention of preterm labour. Front Biosci 12 : 1329 1343. (Pubitemid 46850641)
33. Paradisi R, Fabbri R, Battaglia C, Facchinetti F, Venturoli S (2007). Nitric oxide levels in women with missed and threatened abortion: results of a pilot study. Fertil Steril 88 : 744 748. (Pubitemid 47368250)
34. Pirianov G, Waddington SN, Lindström TM, Terzidou V, Mehmet H, Bennett PR (2009). The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. Endocrinology 150 : 699 706.
35. Pollard JK, Mitchell MD (1996). Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women. Am J Obstet Gynecol 174 : 682 686.
36. Rac VE, Scott CA, Small C, Adamson SL, Rurak D, Challis JR et al. (2007). Dose-dependent effects of meloxicam administration on cyclooxygenase-1 and cyclooxygenase-2 protein expression in intrauterine tissues and fetal tissues of a sheep model of preterm labor. Reprod Sci 14 : 750 764. (Pubitemid 351903564)
37. Ribeiro ML, Perez Martinez S, Farina M, Ogando D, Gimeno M, Franchi AM (1999). The effect of epidermal growth factor on prostaglandin synthesis of oestrogenized rat uterus is mediated by nitric oxide. Prostaglandins Leukot Essent Fatty Acids 61 : 353 358.
38. Ribeiro ML, Aisemberg J, Billi S, Farina MG, Meiss R, McCann S et al. (2005). Epidermal growth factor prevents prepartum luteolysis in the rat. Proc Natl Acad Sci USA 102 : 8048 8053. (Pubitemid 40781060)
39. Romero R, Mazor M, Wu YK, Sirtori M, Oyarzun E, Mitchell MD et al. (1988). Infection in the pathogenesis of preterm labor. Semin Perinatol 12 : 262 279.
40. Romero R, Sirtori M, Oyarzun E, Avila C, Mazor M, Callahan R et al. (1989). Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 161 : 817 824. (Pubitemid 19252813)
41. Romero R, Espinoza J, Chaiworapongsa T, Kalache K (2002). Infection and prematurity and the role of preventive strategies. Semin Neonatol 7 : 259 274. (Pubitemid 35238719)
42. Silver RM, Edwin SS, Trautman MS, Simmons DL, Branch DW, Dudley DJ et al. (1995). Bacterial lipopolysaccharide-mediated fetal death: production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide. J Clin Invest 95 : 725 731.
43. Smith WL, Marnett LJ (1991). Prostaglandin endoperoxide synthase: structure and catalysis. Biochem Biophys Acta 1083 : 1 17.
44. Swaisgood CM, Zu HX, Perkins DJ, Wu S, Garver CL, Zimmerman PD et al. (1997). Coordinate expression of inducible nitric oxide synthase and cyclooxygenase-2 genes in uterine tissues of endotoxin-treated pregnant mice. Am J Obstet Gynecol 177 : 1253 1262. (Pubitemid 27525389)
45. Tunctan B, Ozveren E, Korkmaz B, Buharalioglu CK, Tamer L, Degirmenci U et al. (2006). Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice. Pharmacol Res 53 : 177 192. (Pubitemid 43003487)
46. Unezaki S, Sugatani J, Masu Y, Watanabe K, Ito S (1996). Characterization of prostaglandin F2 alpha production in pregnant and cycling mice. Biol Reprod 55 : 889 894. (Pubitemid 26304768)
47. Wang PH, Cheng MH, Lee WL (2008). The choice of tocolytic drugs for preterm labor - comparison of COX-2 inhibitor and magnesium sulfate. J Obstet Gynaecol Res 34 : 439 440.