Cytotoxic isomalabaricane derivatives and a monocyclic triterpene glycoside from the sponge Rhabdastrella globostellata

Journal of Natural Products

Volumn 73, Issue 9, 2010, Pages 1512-1518

  Hirashima, Miyabi ^a   Tsuda, Kazuomi ^a   Hamada, Toshiyuki ^a   Okamura, Hiroaki ^a   Furukawa, Tatsuhiko ^b   Akiyama, Shin Ichi ^b   Tajitsu, Yusuke ^b   Ikeda, Ryuji ^b   Komatsu, Masaharu ^a   Doe, Matsumi ^c   Morimoto, Yoshiki ^c   Shiro, Motoo ^d   Van Soest, Rob W M ^e   Takemura, Kaoru ^f   Iwagawa, Tetsuo ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c Osaka Prefecture University   (Japan)

^d RIGAKU CORPORATION   (Japan)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f Sankei Kagaku Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; BENZOIC ACID DERIVATIVE; CYCLOPENTANE DERIVATIVE; EPOXIDE; ESTER DERIVATIVE; GLYCOSIDE; PROPIONIC ACID; RHABDASTIN A; RHABDASTIN B; RHABDASTIN C; RHABDASTIN D; RHABDASTIN DEXTRO DIACETIC ACID; RHABDASTIN DEXTRO PARA BROMOBENZOIC ACID; RHABDASTIN E; RHABDASTIN F; RHABDASTIN G; RHABDASTOSIDE A; STELLIFERIN; STELLIFERIN A; STELLIFERIN B; STELLIFERIN C; STELLIFERIN D; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG CYTOTOXICITY; DRUG MECHANISM; HUMAN; HUMAN CELL; IC 50; JAPAN; MASS SPECTROMETRY; PROMYELOCYTIC LEUKEMIA; PROTON NUCLEAR MAGNETIC RESONANCE; RHABDASTRELLA GLOBOSTELLATA; SPONGE (PORIFERA); SUBSTITUTION REACTION; X RAY DIFFRACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; HL 60 CELL LINE; IC50; ISOLATION AND PURIFICATION; X RAY CRYSTALLOGRAPHY;

RHABDASTRELLA;

ANIMALS; ANTINEOPLASTIC AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCOSIDES; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PORIFERA; TRITERPENES;

EID: 77957223040     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np100302a     Document Type: Article

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