A rainbow coalition of lipid transcriptional regulators

Molecular Microbiology

Volumn 78, Issue 1, 2010, Pages 5-8

  Zhang, Yong Mei ^a   Rock, Charles O ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID SYNTHASE; LIPID; MEMBRANE PHOSPHOLIPID; MYCOLIC ACID; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

BACILLUS SUBTILIS; BACTERIAL CELL WALL; BACTERIAL GENE; BACTERIAL MEMBRANE; BACTERIAL METABOLISM; BIOSYNTHESIS; DNA BINDING; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GENE EXPRESSION; LIGAND BINDING; LIPID METABOLISM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN FAMILY; PSEUDOMONAS AERUGINOSA; STREPTOCOCCUS PNEUMONIAE; STREPTOMYCES COELICOLOR; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; LIGANDS; LIPID METABOLISM; LIPIDS; MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES COELICOLOR; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES COELICOLOR;

EID: 77957221235     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2010.07349.x     Document Type: Note

References (23)

1. Arabolaza, A., Rodriguez, E., Altabe, S., Alvarez, H. Gramajo, H. (2008) Multiple pathways for triacylglycerol biosynthesis in Streptomyces coelicolor. Appl Environ Microbiol 74 : 2573 2582. (Pubitemid 351632586)
2. Arabolaza, A., D'Angelo, M., Comba, S. Gramajo, H. (2010) FasR, a novel class of transcriptional regulator, governs the activation of fatty acid biosynthesis genes in Streptomyces coelicolor. Mol Microbiol 78 : 47 63.
3. Campbell, J.W. Cronan, J.E., Jr. (2001) Escherichia coli FadR positively regulates transcription of the fabB fatty acid biosynthetic gene. J Bacteriol 183 : 5982 5990.
4. Cronan, J.E., Jr. Subrahmanyam, S. (1998) FadR, transcriptional co-ordination of metabolic expediency. Mol Microbiol 29 : 937 943. (Pubitemid 28389434)
5. Henry, M.F. Cronan, J.E., Jr. (1992) A new mechanism of transcriptional regulation: release of an activator triggered by small molecule binding. Cell 70 : 671 679.
6. Jerga, A. Rock, C.O. (2009) Acyl-acyl carrier protein regulates transcription of fatty acid biosynthetic genes via the FabT repressor in Streptococcus pneumoniae. J Biol Chem 284 : 15364 15368.
7. Keating, D.H., Carey, M.R. Cronan, J.E., Jr. (1995) The unmodified (Apo) form of Escherichia coli acyl carrier protein is a potent inhibitor of cell growth. J Biol Chem 270 : 22229 22235.
8. Larsen, M.H., Vilcheze, C., Kremer, L., Besra, G.S., Parsons, L., Salfinger, M., et al. (2002) Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis. Mol Microbiol 46 : 453 466. (Pubitemid 35340956)
9. Lu, Y.-J. Rock, C.O. (2006) Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae. Mol Microbiol 59 : 551 566.
10. Miller, D.J., Zhang, Y.-M., Subramainian, C., Rock, C.O. White, S.W. (2010) Transcriptional regulation of membrane lipid homeostasis. Nat Struct Mol Biol 17 : 971 975.
11. Molle, V. Kremer, L. (2010) Division and cell envelope regulation by Ser/Thr phosphorylation: mycobacterium shows the way. Mol Microbiol 75 : 1064 1077.
12. Salzman, V., Mondino, S., Sala, C., Cole, S.T., Gago, G. Gramajo, H. (2010) Transcriptional regulation of lipid homeostasis in mycobacteria. Mol Microbiol 78 : 64 77.
13. Schujman, G.E., Altabe, S. de Mendoza, D. (2008) A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism. Mol Microbiol 68 : 987 996. (Pubitemid 351581062)
14. Schujman, G.E., Guerin, M., Buschiazzo, A., Schaeffer, F., Llarrull, L.I., Reh, G., et al. (2006) Structural basis of lipid biosynthesis regulation in Gram-positive bacteria. EMBO J 25 : 4074 4083. (Pubitemid 44338748)
15. Schujman, G.E., Paoletti, L., Grossman, A.D. de Mendoza, D. (2003) FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. Dev Cell 4 : 663 672. (Pubitemid 36564897)
16. Subramanian, C., Zhang, Y.-M. Rock, C.O. (2010) DesT coordinates the expression of anaerobic and aerobic pathways for unsaturated fatty acid biosynthesis in Pseudomonas aeruginosa. J Bacteriol 192 : 280 285.
17. Waltermann, M., Hinz, A., Robenek, H., Troyer, D., Reichelt, R., Malkus, U., et al. (2005) Mechanism of lipid-body formation in prokaryotes: how bacteria fatten up. Mol Microbiol 55 : 750 763. (Pubitemid 40203691)
18. Zhang, Y.-M. Rock, C.O. (2008) Membrane lipid homeostasis in bacteria. Nat Rev Microbiol 6 : 222 233.
19. Zhang, Y.-M. Rock, C.O. (2009) Transcriptional regulation in bacterial membrane lipid synthesis. J Lipid Res 50 : S115 S119.
20. Zhang, Y.-M., Marrakchi, H. Rock, C.O. (2002) The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli. J Biol Chem 277 : 15558 15565. (Pubitemid 34967824)
21. Zhang, Y.-M., Zhu, K., Frank, M.W. Rock, C.O. (2007) A Pseudomonas aeruginosa transcription factor that senses fatty acid structure. Mol Microbiol 66 : 622 632. (Pubitemid 47621849)
22. Zhu, K., Choi, K.-H., Schweizer, H.P., Rock, C.O. Zhang, Y.-M. (2006) Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa. Mol Microbiol 60 : 260 273.
23. Zhu, K., Zhang, Y.M. Rock, C.O. (2009) Transcriptional regulation of membrane lipid homeostasis in Escherichia coli. J Biol Chem 284 : 34880 34888.