메뉴 건너뛰기




Volumn 28, Issue 3, 2010, Pages 172-187

In vitro evaluation of genotoxicity of avocado (Persea americana) fruit and leaf extracts in human peripheral lymphocytes

Author keywords

Acrocentric associations; avocado; genotoxicity; PCD; Persea Americana

Indexed keywords

ACROCENTRIC ASSOCIATIONS; AVOCADO; GENOTOXICITIES; PCD; PERSEA AMERICANA;

EID: 77957198820     PISSN: 10590501     EISSN: 15324095     Source Type: Journal    
DOI: 10.1080/10590501.2010.504979     Document Type: Article
Times cited : (14)

References (54)
  • 3
    • 0036342912 scopus 로고    scopus 로고
    • Analgesic and anti-inflammatory effects of Persea americana Mill (Lauraceae)
    • Adeyemi OO, Okpo SO, Ogunti OO. Analgesic and anti-inflammatory effects of Persea americana Mill (Lauraceae). Fitoterapia. 2002;73:375-380.
    • (2002) Fitoterapia , vol.73 , pp. 375-380
    • Adeyemi, O.O.1    Okpo, S.O.2    Ogunti, O.O.3
  • 4
    • 34547110136 scopus 로고    scopus 로고
    • Hypoglycemic and hypocholesterolemic potential of Persea americana leaf extracts
    • Brai BI, Odetola AA, Agomo PU. Hypoglycemic and hypocholesterolemic potential of Persea americana leaf extracts. J Med Food. 2007;10(2):356-360.
    • (2007) J Med Food , vol.10 , Issue.2 , pp. 356-360
    • Brai, B.I.1    Odetola, A.A.2    Agomo, P.U.3
  • 5
    • 34347269569 scopus 로고    scopus 로고
    • Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals
    • Ojewole JA, Kamadyaapa DR, Gondwe MM, Moodley K, Musabayane CT. Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals. Cardiovasc J Afr. 2007;18(2):69-76.
    • (2007) Cardiovasc J Afr , vol.18 , Issue.2 , pp. 69-76
    • Ojewole, J.A.1    Kamadyaapa, D.R.2    Gondwe, M.M.3    Moodley, K.4    Musabayane, C.T.5
  • 6
    • 33747227452 scopus 로고    scopus 로고
    • Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice
    • Ojewole JA, Amabeoku GJ. Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice. Phytother Res. 2006;20(8):696-700.
    • (2006) Phytother Res , vol.20 , Issue.8 , pp. 696-700
    • Ojewole, J.A.1    Amabeoku, G.J.2
  • 8
    • 43549107719 scopus 로고    scopus 로고
    • Wound healing activity of Persea americana (avocado) fruit: A preclinical study on rats
    • Nayak BS, Raju SS, Chalapathi Rao AV. Wound healing activity of Persea americana (avocado) fruit: a preclinical study on rats. J Wound Care. 2008;17(3):123-126.
    • (2008) J Wound Care , vol.17 , Issue.3 , pp. 123-126
    • Nayak, B.S.1    Raju, S.S.2    Chalapathi Rao, A.V.3
  • 10
    • 0034717043 scopus 로고    scopus 로고
    • Antifungal compounds from idioblast cells isolated from avocado fruits
    • Domergue F, Helms GL, Prusky D, Browse J. Antifungal compounds from idioblast cells isolated from avocado fruits. Phytochemistry. 2000;54(2):183-189.
    • (2000) Phytochemistry , vol.54 , Issue.2 , pp. 183-189
    • Domergue, F.1    Helms, G.L.2    Prusky, D.3    Browse, J.4
  • 11
    • 0037039708 scopus 로고    scopus 로고
    • Screening of edible Japanese plants for suppressive effects on phorbol ester-induced superoxide generation in differentiated HL-60 cells and AS52 cells
    • Kim HW, Murakami A, Nakamura Y, Ohigashi H. Screening of edible Japanese plants for suppressive effects on phorbol ester-induced superoxide generation in differentiated HL-60 cells and AS52 cells. Cancer Lett. 2002;176:7-16.
    • (2002) Cancer Lett , vol.176 , pp. 7-16
    • Kim, H.W.1    Murakami, A.2    Nakamura, Y.3    Ohigashi, H.4
  • 12
    • 0034328995 scopus 로고    scopus 로고
    • An avocado constituent, persenone A, suppresses expression of inducible forms of nitric oxide synthase and cyclooxygenase in macrophages, and hydrogen peroxide generation in mouse skin
    • Kim OK, Murakami A, Takahashi D, Nakamura Y, Torikai K, Kim HW, Ohigashi H. An avocado constituent, persenone A, suppresses expression of inducible forms of nitric oxide synthase and cyclooxygenase in macrophages, and hydrogen peroxide generation in mouse skin. Biosci Biotechnol Biochem. 2000;64(11):2504-2507.
    • (2000) Biosci Biotechnol Biochem , vol.64 , Issue.11 , pp. 2504-2507
    • Kim, O.K.1    Murakami, A.2    Takahashi, D.3    Nakamura, Y.4    Torikai, K.5    Kim, H.W.6    Ohigashi, H.7
  • 13
    • 68549111227 scopus 로고    scopus 로고
    • Effect of aqueous extracts of alligator pear seed (Persea americana mill) on blood glucose and histopathology of pancreas in alloxaninduced diabetic rats
    • Edem D, Ekanem I, Ebong P. Effect of aqueous extracts of alligator pear seed (Persea americana mill) on blood glucose and histopathology of pancreas in alloxaninduced diabetic rats. Pak J Pharm Sci. 2009;22(3):272-276.
    • (2009) Pak J Pharm Sci , vol.22 , Issue.3 , pp. 272-276
    • Edem, D.1    Ekanem, I.2    Ebong, P.3
  • 15
    • 0345328735 scopus 로고    scopus 로고
    • Avocado-soybean unsaponifiables (ASU) for osteoarthritis - A systematic review
    • Ernst E. Avocado-soybean unsaponifiables (ASU) for osteoarthritis-a systematic review. Clin Rheumatol. 2003;22(4-5):285-288.
    • (2003) Clin Rheumatol , vol.22 , Issue.4-5 , pp. 285-288
    • Ernst, E.1
  • 16
    • 33748536108 scopus 로고    scopus 로고
    • Effect of interleukin-1beta on transforming growth factor-beta and bone morphogenetic protein-2 expression in human periodontal ligament and alveolar bone cells in culture: Modulation by avocado and soybean unsaponifiables
    • Andriamanalijaona R, Benateau H, Barre PE, Boumediene K, Labbe D, Compere JF, Pujol JP. Effect of interleukin-1beta on transforming growth factor-beta and bone morphogenetic protein-2 expression in human periodontal ligament and alveolar bone cells in culture: modulation by avocado and soybean unsaponifiables. J Periodontol. 2006;77(7):1156-1166.
    • (2006) J Periodontol , vol.77 , Issue.7 , pp. 1156-1166
    • Andriamanalijaona, R.1    Benateau, H.2    Barre, P.E.3    Boumediene, K.4    Labbe, D.5    Compere, J.F.6    Pujol, J.P.7
  • 17
    • 0035741819 scopus 로고    scopus 로고
    • Vitamin B(12) cream containing avocado oil in the therapy of plaque psoriasis
    • Stücker M, Memmel U, Hoffmann M, Hartung J, Altmeyer P. Vitamin B(12) cream containing avocado oil in the therapy of plaque psoriasis. Dermatology. 2001;203(2):141-147.
    • (2001) Dermatology , vol.203 , Issue.2 , pp. 141-147
    • Stücker, M.1    Memmel, U.2    Hoffmann, M.3    Hartung, J.4    Altmeyer, P.5
  • 18
    • 74149084571 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate
    • Heinecke LF, Grzanna MW, Au AY, Mochal CA, Rashmir-Raven A, Frondoza CG. Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate. Osteoarthritis Cartilage. 2010;18(2):220-227.
    • (2010) Osteoarthritis Cartilage. , vol.18 , Issue.2 , pp. 220-227
    • Heinecke, L.F.1    Grzanna, M.W.2    Au, A.Y.3    Mochal, C.A.4    Rashmir-Raven, A.5    Frondoza, C.G.6
  • 19
    • 0021200358 scopus 로고
    • Toxicity of avocado (Persea americana (Guatemalan var)) leaves: Review and preliminary report
    • Craigmill AL, Eide RN, Shultz TA, Hedrick K. Toxicity of avocado (Persea americana (Guatemalan var)) leaves: review and preliminary report. Vet Hum Toxicol. 1984;26(5):381-383.
    • (1984) Vet Hum Toxicol , vol.26 , Issue.5 , pp. 381-383
    • Craigmill, A.L.1    Eide, R.N.2    Shultz, T.A.3    Hedrick, K.4
  • 20
    • 0028784830 scopus 로고
    • Isolation and identification of a compound from avocado (Persea americana) leaves which causes necrosis of the acinar epithelium of the lactating mammary gland and the myocardium
    • Oelrichs PB, Ng JC, Seawright AA, Ward A, Schäffeler L, MacLeod JK. Isolation and identification of a compound from avocado (Persea americana) leaves which causes necrosis of the acinar epithelium of the lactating mammary gland and the myocardium. Nat Toxins. 1995;3(5):344-349.
    • (1995) Nat Toxins , vol.3 , Issue.5 , pp. 344-349
    • Oelrichs, P.B.1    Ng, J.C.2    Seawright, A.A.3    Ward, A.4    Schäffeler, L.5    MacLeod, J.K.6
  • 22
    • 0026266212 scopus 로고
    • Suspected avocado (Persea americana) poisoning in goats
    • Stadler P, VanRensburg IB, Naud́e TW. Suspected avocado (Persea americana) poisoning in goats. J S Afr Vet Assoc. 1991;62(4):186-188.
    • (1991) J S Afr Vet Assoc , vol.62 , Issue.4 , pp. 186-188
    • Stadler, P.1    Vanrensburg, I.B.2    Naud́e, T.W.3
  • 24
    • 0028506157 scopus 로고
    • Cardiomyopathy in ostriches (Struthio camelus) due to avocado (Persea americana var. guatemalensis) intoxication
    • Burger WP, Naud́e TW, VanRensburg IB, Botha CJ, Pienaar AC. Cardiomyopathy in ostriches (Struthio camelus) due to avocado (Persea americana var. guatemalensis) intoxication. J S Afr Vet Assoc. 1994;65(3):113-118.
    • (1994) J S Afr Vet Assoc , vol.65 , Issue.3 , pp. 113-118
    • Burger, W.P.1    Naud́e, T.W.2    Vanrensburg, I.B.3    Botha, C.J.4    Pienaar, A.C.5
  • 25
    • 0031821220 scopus 로고    scopus 로고
    • Cytotoxic and insecticidal constituents of the unripe fruit of Persea americana
    • Oberlies NH, Rogers LL, Martin JM, McLaughlin JL. Cytotoxic and insecticidal constituents of the unripe fruit of Persea americana. J Nat Prod. 1998;61(6):781-785.
    • (1998) J Nat Prod , vol.61 , Issue.6 , pp. 781-785
    • Oberlies, N.H.1    Rogers, L.L.2    Martin, J.M.3    McLaughlin, J.L.4
  • 26
    • 0031694649 scopus 로고    scopus 로고
    • Isolation, identification, and biological activity of isopersin, a new compound from avocado idioblast oil cells
    • Rodriguez-Saona C, Millar JG, Trumble JT. Isolation, identification, and biological activity of isopersin, a new compound from avocado idioblast oil cells. J Nat Prod. 1998;61:1168-1170.
    • (1998) J Nat Prod , vol.61 , pp. 1168-1170
    • Rodriguez-Saona, C.1    Millar, J.G.2    Trumble, J.T.3
  • 27
    • 0032962289 scopus 로고    scopus 로고
    • Antifungal diene in leaves of various avocado cultivars
    • Carman RM, Handley PN. Antifungal diene in leaves of various avocado cultivars. Phytochemistry. 1999;50:1329-1331.
    • (1999) Phytochemistry , vol.50 , pp. 1329-1331
    • Carman, R.M.1    Handley, P.N.2
  • 28
    • 35948972876 scopus 로고    scopus 로고
    • Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism
    • Roberts CG, Gurisik E, Biden TJ, Sutherland RL, Butt AJ. Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism. Mol Cancer Ther. 2007;6(10):2777-2785.
    • (2007) Mol Cancer Ther , vol.6 , Issue.10 , pp. 2777-2785
    • Roberts, C.G.1    Gurisik, E.2    Biden, T.J.3    Sutherland, R.L.4    Butt, A.J.5
  • 30
    • 0038248633 scopus 로고    scopus 로고
    • Novel nitric oxide and superoxide generation inhibitors, persenone A and B, from avocado fruit
    • Kim OK, Murakami A, Nakamura Y, Takeda N, Yoshizumi H, Ohigashi H. Novel nitric oxide and superoxide generation inhibitors, persenone A and B, from avocado fruit. J Agric Food Chem. 2000;48(5):1557-1563.
    • (2000) J Agric Food Chem , vol.48 , Issue.5 , pp. 1557-1563
    • Kim, O.K.1    Murakami, A.2    Nakamura, Y.3    Takeda, N.4    Yoshizumi, H.5    Ohigashi, H.6
  • 32
    • 24944590786 scopus 로고    scopus 로고
    • Trypanocidal constituents in plants 5. Evaluation of some Mexican plants for their trypanocidal activity and active constituents in the seeds of Persea Americana
    • Abe F, Nagafuji S, Okawa M, Kinjo J, Akahane H, Ogura T, et al. Trypanocidal constituents in plants 5. Evaluation of some Mexican plants for their trypanocidal activity and active constituents in the seeds of Persea americana. Biol Pharm Bull. 2005;28:1314-1317.
    • (2005) Biol Pharm Bull , vol.28 , pp. 1314-1317
    • Abe, F.1    Nagafuji, S.2    Okawa, M.3    Kinjo, J.4    Akahane, H.5    Ogura, T.6
  • 33
  • 35
  • 36
    • 0034520535 scopus 로고    scopus 로고
    • Biologically active aliphatic acetogenins from specialized idioblast oil cells
    • Rodriguez-Saona C, Trumble JT. Biologically active aliphatic acetogenins from specialized idioblast oil cells. Curr Org Chem. 2000;4:1249-1260.
    • (2000) Curr Org Chem , vol.4 , pp. 1249-1260
    • Rodriguez-Saona, C.1    Trumble, J.T.2
  • 38
    • 0029955753 scopus 로고    scopus 로고
    • In vitro virucidal and virustatic anti HIV-1 effects of extracts from Persea americana Mill. (avocado) leaves
    • Wigg MD, Al-Jabri AA, Costa SS, Race E, Bodo B, Oxford JS. In vitro virucidal and virustatic anti HIV-1 effects of extracts from Persea americana Mill. (avocado) leaves. Antivir Chem Chemother. 1996;7:179-183.
    • (1996) Antivir Chem Chemother , vol.7 , pp. 179-183
    • Wigg, M.D.1    Al-Jabri, A.A.2    Costa, S.S.3    Race, E.4    Bodo, B.5    Oxford, J.S.6
  • 39
    • 0032424388 scopus 로고    scopus 로고
    • Flavonol monoglycosides isolated from the antiviral fractions of Persea americana (Lauraceae) leaf infusion
    • De Almeida AP, Miranda MMFS, Simoni IC, Wigg MD, Lagrota MHC, Costa SS. Flavonol monoglycosides isolated from the antiviral fractions of Persea americana (Lauraceae) leaf infusion. Phytother Res. 1998;12:562-567.
    • (1998) Phytother Res , vol.12 , pp. 562-567
    • De Almeida, A.P.1    Mmfs, M.2    Simoni, I.C.3    Wigg, M.D.4    Mhc, L.5    Costa, S.S.6
  • 44
    • 0017055657 scopus 로고
    • Acrocentric chromosome associations in man
    • Jacobs PA, Mayer M, Morton NE. Acrocentric chromosome associations in man. Am J Hum Genet. 1976;28:567-576.
    • (1976) Am J Hum Genet , vol.28 , pp. 567-576
    • Jacobs, P.A.1    Mayer, M.2    Morton, N.E.3
  • 45
    • 0014644593 scopus 로고
    • Number of each type of acrocentric association and probability of its occurrence in human male and female metaphase cells
    • Galperin H. Number of each type of acrocentric association and probability of its occurrence in human male and female metaphase cells. Cytogenetics. 1969;8:439-446.
    • (1969) Cytogenetics , vol.8 , pp. 439-446
    • Galperin, H.1
  • 46
    • 0016725631 scopus 로고
    • Compensatory mechanism in the satellite association patterns of individuals with Robertsonian translocations
    • Hansson A. Compensatory mechanism in the satellite association patterns of individuals with Robertsonian translocations. Hereditas. 1975;81:101-112.
    • (1975) Hereditas , vol.81 , pp. 101-112
    • Hansson, A.1
  • 47
    • 0018365296 scopus 로고
    • Relationship between satellite association and the occurrence of non-disjunction in man
    • Houghton JA. Relationship between satellite association and the occurrence of non-disjunction in man. Mutat Res. 1979;61(1):103-114.
    • (1979) Mutat Res , vol.61 , Issue.1 , pp. 103-114
    • Houghton, J.A.1
  • 48
    • 0032746299 scopus 로고    scopus 로고
    • The frequency of induced premature centromere division in human populations occupationally exposed to genotoxic chemicals
    • Major J, Jakab MG, Tompa A. The frequency of induced premature centromere division in human populations occupationally exposed to genotoxic chemicals. Mutat Res. 1999;445(2):241-249.
    • (1999) Mutat Res , vol.445 , Issue.2 , pp. 241-249
    • Major, J.1    Jakab, M.G.2    Tompa, A.3
  • 50
    • 0031614809 scopus 로고    scopus 로고
    • Effect of polycyclic aromatic hydrocarbons on somatic chromosomes of coal tar workers
    • Yadav JS, Seth N. Effect of polycyclic aromatic hydrocarbons on somatic chromosomes of coal tar workers. Cytobios. 1998;93(347):165-173.
    • (1998) Cytobios , vol.93 , Issue.347 , pp. 165-173
    • Yadav, J.S.1    Seth, N.2
  • 51
    • 0346978047 scopus 로고    scopus 로고
    • Cytogenetic damage in plastic industry workers exposed to polyvinyl chloride
    • Yadav JS, Chhillar AK. Cytogenetic damage in plastic industry workers exposed to polyvinyl chloride. Cytobios. 2001;104(407):173-187.
    • (2001) Cytobios , vol.104 , Issue.407 , pp. 173-187
    • Yadav, J.S.1    Chhillar, A.K.2
  • 52
    • 0030068476 scopus 로고    scopus 로고
    • Effect of sulphur dioxide exposure on human chromosomes
    • Yadav JS, Kaushik VK. Effect of sulphur dioxide exposure on human chromosomes. Mutat Res. 1996;359(1):25-29.
    • (1996) Mutat Res , vol.359 , Issue.1 , pp. 25-29
    • Yadav, J.S.1    Kaushik, V.K.2
  • 53
    • 0034136681 scopus 로고    scopus 로고
    • Cytogenetic damage in bidi smokers
    • Yadav JS, Thakur S. Cytogenetic damage in bidi smokers. Nicotine Tob Res. 2000;2(1):97-103.
    • (2000) Nicotine Tob Res , vol.2 , Issue.1 , pp. 97-103
    • Yadav, J.S.1    Thakur, S.2
  • 54
    • 33846504995 scopus 로고    scopus 로고
    • Genotoxic effects induced by Fotemustine and Vinorelbine in human lymphocytes
    • Celikler S, Bilaloǧlu R, Aydemir N. Genotoxic effects induced by Fotemustine and Vinorelbine in human lymphocytes. Z. Naturforsch. 2006;61c:903-910.
    • (2006) Z. Naturforsch , vol.61 , pp. 903-910
    • Celikler, S.1    Bilaloǧlu, R.2    Aydemir, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.