Molecular-assisted immunohistochemical optimization

Acta Histochemica

Volumn 112, Issue 6, 2010, Pages 519-528

  Mohd Omar, Mohd Feroz ^a,b   Huang, Ning ^c,d   Ou, Keli ^c,d   Yu, Kun ^e   Putti, Thomas C ^f   Jikuya, Hiroyuki ^c,d   Ichikawa, Tetsuo ^c,d   Nishimura, Osamu ^g   Tan, Patrick ^c,e,h,i   Salto Tellez, Manuel ^a,f  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c Agenica Research Pte Ltd   (Singapore)

^d Shimadzu (Asia Pacific) Pte Ltd   (Singapore)

^e DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^f NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^g SHIMADZU CORPORATION   (Japan)

^h GENOME INSTITUTE OF SINGAPORE   (Singapore)

ⁱ DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Antibody optimization; Immunohistochemistry validation; Molecular biology; Molecular diagnostics; Protein immunolocalization

Indexed keywords

26S PROTEASOME NON ADENOSINE TRIPHOSPHATASE REGULATORY SUBUNIT 2; 6 PHOSPHOGLUCONOLACTONASE; F ACTIN CAPPING PROTEIN ALPHA 2 SUBUNIT; PROLIFERATED ASSOCIATED PROTEIN 2G4; PROTEIN ANTIBODY; TRANSKETOLASE; TUMOR MARKER; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ANTIGEN RETRIEVAL; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MOLECULAR BIOLOGY; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEOMICS; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGEN-ANTIBODY REACTIONS; BREAST NEOPLASMS; CAPZ ACTIN CAPPING PROTEIN; CARBOXY-LYASES; CARBOXYLIC ESTER HYDROLASES; HUMANS; IMMUNOHISTOCHEMISTRY; PARAFFIN EMBEDDING; REPRODUCIBILITY OF RESULTS; RNA-BINDING PROTEINS; TISSUE FIXATION; TRANSKETOLASE; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 77957172724     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2009.05.010     Document Type: Article

References (43)

1. Ainsworth R., Bartlett J.M., Going J.J., Mallon E.A., Forsyth A., Richmond J., et al. IHC for Her2 with CBE356 antibody is a more accurate predictor of Her2 gene amplification by FISH than HercepTest in breast carcinoma. J Clin Pathol 2005, 58:1086-1090.
2. Bahia H., Ashman J.N., Cawkwell L., Lind M., Monson J.R., Drew P.J., et al. Karyotypic variation between independently cultured strains of the cell line MCF-7 identified by multicolour fluorescence in situ hybridization. Int J Oncol 2002, 20:489-494.
3. Biesterfeld S., Veuskens U., Schmitz F.J., Amo-Takyi B., Bocking A. Interobserver reproducibility of immunocytochemical estrogen- and progesterone receptor status assessment in breast cancer. Anticancer Res 1996, 16:2497-2500.
4. Boenisch T. Effect of heat-induced antigen retrieval following inconsistent formalin fixation. Appl Immunohistochem Mol Morphol 2005, 13:283-286.
5. Boenisch T. Heat-induced antigen retrieval: what are we retrieving?. J Histochem Cytochem 2006, 54:961-964.
6. Burdall S.E., Hanby A.M., Lansdown M.R., Speirs V. Breast cancer cell lines: friend or foe?. Breast Cancer Res 2003, 5:89-95.
7. Burow M.E., Weldon C.B., Tang Y., Navar G.L., Krajewski S., Reed J.C., et al. Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants. Cancer Res 1998, 58:4940-4946.
8. Dong S., Stenoien D.L., Qiu J., Mancini M.A., Tweardy D.J. Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha. Mol Cell Biol 2004, 24:4465-4475.
9. Douglas-Jones A., Shah V., Morgan J., Dallimore N., Rashid M. Observer variability in the histopathological reporting of core biopsies of papillary breast lesions is reduced by the use of immunohistochemistry for CK5/6, calponin and p63. Histopathology 2005, 47:202-208.
10. Goldstein N.S., Hewitt S.M., Taylor C.R., Yaziji H., Hicks D.G. Recommendations for improved standardization of immunohistochemistry. Appl Immunohistochem Mol Morphol 2007, 15:124-133.
11. Guda C. pTARGET: a web server for predicting protein subcellular localization. Nucleic Acids Res 2006, 34:W210-W213.
12. Hoglund A., Donnes P., Blum T., Adolph H.-W., Kohlbacher O. MultiLoc: prediction of protein subcellular localization using N-terminal targeting sequences, sequence motifs and amino acid composition. Bioinformatics 2006, 22:1158-1165.
13. Horton P., Park K.J., Obayashi T., Fujita N., Harada H., Adams-Collier C.J., et al. WoLF PSORT: protein localization predictor. Nucleic Acids Res 2007, 35:W585-W587.
14. Ito K., Liu Q., Salto-Tellez M., Yano T., Tada K., Ida H., et al. RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. Cancer Res 2005, 65:7743-7750.
15. Lau Q.C., Raja E., Salto-Tellez M., Liu Q., Ito K., Inoue M., et al. RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. Cancer Res 2006, 66:6512-6520.
16. Levenson A.S., Jordan V.C. MCF-7: the first hormone-responsive breast cancer cell line. Cancer Res 1997, 57:3071-3078.
17. Maitra A., Arking D.E., Shivapurkar N., Ikeda M., Stastny V., Kassauei K., et al. Genomic alterations in cultured human embryonic stem cells. Nat Genet 2005, 37:1099-1103.
18. McCabe A., Dolled-Filhart M., Camp R.L., Rimm D.L. Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst 2005, 97:1808-1815.
19. McShane L.M., Aamodt R., Cordon-Cardo C., Cote R., Faraggi D., Fradet Y., et al. Reproducibility of p53 immunohistochemistry in bladder tumors. National Cancer Institute, Bladder Tumor Marker Network. Clin Cancer Res 2000, 6:1854-1864.
20. Mengel M., Wasielewski R., Wiese B., Rudiger T., Muller-Hermelink H.K., Kreipe H. Inter-laboratory and inter-observer reproducibility of immunohistochemical assessment of the Ki-67 labelling index in a large multi-centre trial. J Pathol 2002, 198:292-299.
21. Motti M.L, Califano D., Troncone G., Marco C., Migliaccio I., Palmieri E., et al. Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization. Am J Pathol 2005, 166:737-749.
22. Nair R., Rost B. Mimicking cellular sorting improves prediction of subcellular localization. J Mol Biol 2005, 348:85-100.
23. Nakai K., Horton P. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem Sci 1999, 24:34-36.
24. Nazareth L.V., Stenoien D.L., Bingman W.E, James a.J., Wu C., Zhang Y., et al. C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1). Mol Endocrinol 1999, 13:2065-2075.
25. Nedergaard L., Haerslev T., Jacobsen G.K. Immunohistochemical study of estrogen receptors in primary breast carcinomas and their lymph node metastases including comparison of two monoclonal antibodies. APMIS 1995, 103:20-24.
26. Nugoli M., Chuchana P., Vendrell J., Orsetti B., Ursule L., Nguyen C., et al. Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications. BMC Cancer 2003, 3:13.
27. Osborne C.K., Hobbs K., Trent J.M. Biological differences among MCF-7 human breast cancer cell lines from different laboratories. Breast Cancer Res Treat 1987, 9:111-121.
28. Ou K., Yu K., Kesuma D., Hooi M., Huang N., Chen W., et al. Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping. J Proteome Res 2008, 7:1518-1528.
29. Parker R.L., Huntsman D.G., Lesack D.W., Cupples J.B., Grant D.R., Akbari M., et al. Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray. Am J Clin Pathol 2002, 117:723-728.
30. Perez E.A., Suman V.J., Davidson N.E., Martino S., Kaufman P.A., Lingle W.L., et al. HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial. J Clin Oncol 2006, 24:3032-3038.
31. Press M.F., Hung G., Godolphin W., Slamon D.J. Sensitivity of HER-2/neu antibodies in archival tissue samples: potential source of error in immunohistochemical studies of oncogene expression. Cancer Res 1994, 54:2771-2777.
32. Press M.F., Slamon D.J., Flom K.J., Park J., Zhou J.Y., Bernstein L. Evaluation of HER-2/neu gene amplification and overexpression: comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens. J Clin Oncol 2002, 20:3095-3105.
33. Ramos-Vara J.A. Technical aspects of immunohistochemistry. Vet Pathol 2005, 42:405-426.
34. Rodriguez J.A., Au W.W., Henderson B.R. Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain. Exp Cell Res 2004, 293:14-21.
35. Rojo M.G., Garcia G.B., Mateos C.P., Garcia J.G., Vicente M.C. Critical comparison of 31 commercially available digital slide systems in pathology. Int J Surg Pathol 2006, 14:285-305.
36. Salto-Tellez M.A. Case for integrated morphomolecular diagnostic pathologists. Clin Chem 2007, 53:1188-1190.
37. Schneider G., Fechner U. Advances in the prediction of protein targeting signals. Proteomics 2004, 4:1571-1580.
38. Shatkay H., Hoglund A., Brady S., Blum T., Donnes P., Kohlbacher O. SherLoc: high-accuracy prediction of protein subcellular localization by integrating text and protein sequence data. Bioinformatics 2007, 23:1410-1417.
39. Shi S.-R., Cote R.J., Taylor C.R. Antigen retrieval immunohistochemistry: past, present, and future. J Histochem Cytochem 1997, 45:327-344.
40. Shi S.-R., Cote R.J., Taylor C.R. Antigen retrieval techniques: current perspectives. J Histochem Cytochem 2001, 49:931-938.
41. Soong R., Robbins P.D., Dix B.R., Grieu F., Lim B., Knowles S., et al. Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas. Hum Pathol 1996, 27:1050-1055.
42. Soule H.D., Vazguez J., Long A., Albert S., Brennan M.A. Human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 1973, 51:1409-1416.
43. Wasielewski R., Mengel M., Wiese B., Rudiger T., Muller-Hermelink H.K., Kreipe H. Tissue array technology for testing interlaboratory and interobserver reproducibility of immunohistochemical estrogen receptor analysis in a large multicenter trial. Am J Clin Pathol 2002, 118:675-682.