메뉴 건너뛰기




Volumn 117, Issue 1, 2010, Pages 1-10

Stem cell therapy for myocardial infarction: Are we missing time?

Author keywords

Bone marrow; Clinical trials; Myocardial infarction; Stem cell therapy; Timing

Indexed keywords

ADENOSINE; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; MONOCYTE CHEMOTACTIC PROTEIN 3; PHOSPHATE BUFFERED SALINE; PLACEBO; REACTIVE OXYGEN METABOLITE; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 77957157181     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000318840     Document Type: Review
Times cited : (23)

References (61)
  • 1
    • 42649122962 scopus 로고    scopus 로고
    • Stem cells in the heart: What's the buzz all about? I. Preclinical considerations
    • Smith RR, Barile L, Messina E, Marbán E: Stem cells in the heart: what's the buzz all about? I. Preclinical considerations. Heart Rhythm 2008; 5:749-757.
    • (2008) Heart Rhythm , vol.5 , pp. 749-757
    • Smith, R.R.1    Barile, L.2    Messina, E.3    Marbán, E.4
  • 5
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardio-myocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher AA, Schuster MD, Szabolcs MJ, Ta-kuma S, Burkhoff D, Wang J, Homma S, Edwards NM, Itescu S: Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardio-myocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001; 7: 430-436.
    • (2001) Nat Med , vol.7 , pp. 430-436
    • Kocher, A.A.1    Schuster, M.D.2    Szabolcs, M.J.3    Ta-Kuma, S.4    Burkhoff, D.5    Wang, J.6    Homma, S.7    Edwards, N.M.8    Itescu, S.9
  • 11
    • 69249132964 scopus 로고    scopus 로고
    • Impact of ti ming on efficacy and safety of intracoronary autolo-gous bone mar row stem cel ls t ranspla nt ation in acute myocardial infarction: A pooled subgroup analysis of randomized controlled trials
    • Zhang S, Sun A, Xu D, Yao K, Huang Z, Jin H, Wang K, Z ou Y, Ge J: Impact of ti ming on efficacy and safety of intracoronary autolo-gous bone mar row stem cel ls t ranspla nt ation in acute myocardial infarction: a pooled subgroup analysis of randomized controlled trials. Clin Cardiol 2009; 32: 458-466.
    • (2009) Clin Cardiol , vol.32 , pp. 458-466
    • Zhang, S.1    Sun, A.2    Xu, D.3    Yao, K.4    Huang, Z.5    Jin, H.6    Wang, K.7    Zou, Y.8    Ge, J.9
  • 13
    • 0035665771 scopus 로고    scopus 로고
    • Optimal time for cardiomyocyte transplantation to maximize myocardial function after left ventricular injury
    • Li RK, Mickle DA, Weisel RD, Rao V, Jia ZQ: Optimal time for cardiomyocyte transplantation to maximize myocardial function after left ventricular injury. Ann Thorac Surg 2001; 72: 1957-1963.
    • (2001) Ann Thorac Surg , vol.72 , pp. 1957-1963
    • Li, R.K.1    Mickle, D.A.2    Weisel, R.D.3    Rao, V.4    Jia, Z.Q.5
  • 14
    • 33644616737 scopus 로고    scopus 로고
    • Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarction
    • Bartunek J, Wijns W, Heyndrickx GR, Van-derheyden M: Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarction. Nat Clin Pract Cardiovasc Med 2006; 3(suppl 1):S52-S56.
    • (2006) Nat Clin Pract Cardiovasc Med , vol.3 , Issue.SUPPL. 1
    • Bartunek, J.1    Wijns, W.2    Heyndrickx, G.R.3    Van-Derheyden, M.4
  • 16
    • 33847302010 scopus 로고    scopus 로고
    • Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction
    • DOI 10.1016/j.ejcts.2006.11.057, PII S101079400601089X
    • Hu X, Wang J, Chen J, Luo R, He A, Xie X, Li J: Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction. Eur J Cardiothorac Surg 2007; 31:438-443. (Pubitemid 46329387)
    • (2007) European Journal of Cardio-thoracic Surgery , vol.31 , Issue.3 , pp. 438-443
    • Hu, X.1    Wang, J.2    Chen, J.3    Luo, R.4    He, A.5    Xie, X.6    Li, J.7
  • 17
  • 18
    • 0015042034 scopus 로고
    • The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats
    • Hill JH, Ward PA: The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats. J Exp Med 1971; 133: 885-900.
    • (1971) J Exp Med , vol.133 , pp. 885-900
    • Hill, J.H.1    Ward, P.A.2
  • 19
    • 0026490182 scopus 로고
    • Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury
    • Dreyer WJ, Michael LH, Nguyen T, Smith CW, Anderson DC, Entman ML, Rossen RD: Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury. Circ Res 1992; 71: 1518-1524.
    • (1992) Circ Res , vol.71 , pp. 1518-1524
    • Dreyer, W.J.1    Michael, L.H.2    Nguyen, T.3    Smith, C.W.4    Anderson, D.C.5    Entman, M.L.6    Rossen, R.D.7
  • 20
    • 0029070807 scopus 로고
    • Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit: Evidence for a role for C5a and interleukin-8
    • Ivey CL, Williams FM, Collins PD, Jose PJ, Williams TJ: Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit: evidence for a role for C5a and interleukin-8. J Clin Invest 1995; 95:2720-2728.
    • (1995) J Clin Invest , vol.95 , pp. 2720-2728
    • Ivey, C.L.1    Williams, F.M.2    Collins, P.D.3    Jose, P.J.4    Williams, T.J.5
  • 21
    • 0024203618 scopus 로고
    • Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury
    • Granger DN: Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988; 255: 1269-1275.
    • (1988) Am J Physiol , vol.255 , pp. 1269-1275
    • Granger, D.N.1
  • 22
    • 0026059929 scopus 로고
    • Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils
    • Patel KD, Zimmerman GA, Prescott SM, McEver RP, McIntyre TM: Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol 1991; 112:749-759.
    • (1991) J Cell Biol , vol.112 , pp. 749-759
    • Patel, K.D.1    Zimmerman, G.A.2    Prescott, S.M.3    McEver, R.P.4    McIntyre, T.M.5
  • 23
    • 0028351137 scopus 로고
    • Reactive oxygen species rapidly increase endothelial ICAM-1 ability to bind neutrophils without detectable upregulation
    • Sellak H, Franzini E, Hakim J, Pasquier C: Reactive oxygen species rapidly increase endothelial ICAM-1 ability to bind neutrophils without detectable upregulation. Blood 1994; 83: 2669-2677.
    • (1994) Blood , vol.83 , pp. 2669-2677
    • Sellak, H.1    Franzini, E.2    Hakim, J.3    Pasquier, C.4
  • 26
    • 0345275943 scopus 로고    scopus 로고
    • Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair
    • Virag JI, Murry CE: Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol 2003; 163:2433-2440.
    • (2003) Am J Pathol , vol.163 , pp. 2433-2440
    • Virag, J.I.1    Murry, C.E.2
  • 27
    • 78650014429 scopus 로고    scopus 로고
    • The heart
    • Rubin R, Strayer DS (eds) ed 5. Philadelphia, Lippincott Williams & Wilkins
    • Saffitz JE: The heart; in Rubin R, Strayer DS (eds): Rubin's Pathology: Clinicopathologic Foundations of Medicine, ed 5. Philadelphia, Lippincott Williams & Wilkins, 2007, pp 427-481.
    • (2007) Rubin's Pathology: Clinicopathologic Foundations of Medicine , pp. 427-481
    • Saffitz, J.E.1
  • 28
    • 0034074371 scopus 로고    scopus 로고
    • Infarct scar: A dynamic tissue
    • Sun Y, Weber KT: Infarct scar: a dynamic tissue. Cardiovasc Res 2000; 46:250-256.
    • (2000) Cardiovasc Res , vol.46 , pp. 250-256
    • Sun, Y.1    Weber, K.T.2
  • 30
    • 33744502363 scopus 로고    scopus 로고
    • Changes in circulating mesenchymal stem cells, stem cell homing factor, and vascular growth factors in patients with acute ST elevation myocardial infarction treated with primary percutaneous coronary intervention
    • Wang Y, Johnsen HE, Mortensen S, Bindslev L, Ripa RS, Haack-Sørensen M, Jørgensen E, Fang W, Kastrup J: Changes in circulating mesenchymal stem cells, stem cell homing factor, and vascular growth factors in patients with acute ST elevation myocardial infarction treated with primary percutaneous coronary intervention. Heart 2006; 92:768-774.
    • (2006) Heart , vol.92 , pp. 768-774
    • Wang, Y.1    Johnsen, H.E.2    Mortensen, S.3    Bindslev, L.4    Ripa, R.S.5    Haack-Sørensen, M.6    Jørgensen, E.7    Fang, W.8    Kastrup, J.9
  • 31
    • 58149169162 scopus 로고    scopus 로고
    • Cardiogenic differentiation and trans-differentiation of progenitor cells
    • Reinecke H, Minami E, Zhu WZ, Laflamme MA: Cardiogenic differentiation and trans-differentiation of progenitor cells. Circ Res 2008; 103:1058-1071.
    • (2008) Circ Res , vol.103 , pp. 1058-1071
    • Reinecke, H.1    Minami, E.2    Zhu, W.Z.3    Laflamme, M.A.4
  • 34
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1a plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott JD, Huang Y, Liu D, Hickey R, Krause DS, Giordano FJ: Stromal cell-derived factor-1a plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004; 110:3300-3305.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1    Huang, Y.2    Liu, D.3    Hickey, R.4    Krause, D.S.5    Giordano, F.J.6
  • 37
    • 25144491290 scopus 로고    scopus 로고
    • Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction
    • Ma J, Ge J, Zhang S, Sun A, Shen J, Chen L, Wang K, Zou Y: Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction. Basic Res Cardiol 2005; 100:217-223.
    • (2005) Basic Res Cardiol , vol.100 , pp. 217-223
    • Ma, J.1    Ge, J.2    Zhang, S.3    Sun, A.4    Shen, J.5    Chen, L.6    Wang, K.7    Zou, Y.8
  • 38
    • 42249108334 scopus 로고    scopus 로고
    • Stem cell factor/c-kit signaling mediated cardiac stem cell migration via activation of p38 MAPK
    • Kuang D, Zhao X, Xiao G, Ni J, Feng Y, Wu R, Wang G: Stem cell factor/c-kit signaling mediated cardiac stem cell migration via activation of p38 MAPK. Basic Res Cardiol 2008; 103: 265-273.
    • (2008) Basic Res Cardiol , vol.103 , pp. 265-273
    • Kuang, D.1    Zhao, X.2    Xiao, G.3    Ni, J.4    Feng, Y.5    Wu, R.6    Wang, G.7
  • 39
    • 76749134657 scopus 로고    scopus 로고
    • Engraftment is optimal when myoblasts are transplanted early: The role of hepatocyte growth factor
    • O'Blenes SB, Li AW, Chen R, Arora RC, Horackova M: Engraftment is optimal when myoblasts are transplanted early: the role of hepatocyte growth factor. Ann Thorac Surg 2010; 89:829-835.
    • (2010) Ann Thorac Surg , vol.89 , pp. 829-835
    • O'Blenes, S.B.1    Li, A.W.2    Chen, R.3    Arora, R.C.4    Horackova, M.5
  • 43
    • 33644634616 scopus 로고    scopus 로고
    • Bone-marrow-derived cell transfer after ST-elevation myocardial infarction: Lessons from the BOOST trial
    • Drexler H, Meyer GP, Wollert KC: Bone-marrow-derived cell transfer after ST-elevation myocardial infarction: lessons from the BOOST trial. Nat Clin Pract Cardiovasc Med 2006; 3(suppl 1):S65-S68.
    • (2006) Nat Clin Pract Cardiovasc Med , vol.3 , Issue.SUPPL. 1
    • Drexler, H.1    Meyer, G.P.2    Wollert, K.C.3
  • 44
    • 38849139759 scopus 로고    scopus 로고
    • Local injection of stem cell factor (SCF) improves myocardial homing of systemical-ly delivered c-kit + bone marrow-derived stem cells
    • Lutz M, Rosenberg M, Kiessling F, Eckstein V, Heger T, Krebs J, Ho AD, Katus HA, Frey N: Local injection of stem cell factor (SCF) improves myocardial homing of systemical-ly delivered c-kit + bone marrow-derived stem cells. Cardiovasc Res 2008; 77:143-150.
    • (2008) Cardiovasc Res , vol.77 , pp. 143-150
    • Lutz, M.1    Rosenberg, M.2    Kiessling, F.3    Eckstein, V.4    Heger, T.5    Krebs, J.6    Ho, A.D.7    Katus, H.A.8    Frey, N.9
  • 45
    • 35248875838 scopus 로고    scopus 로고
    • SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction
    • DOI 10.1096/fj.06-6558com
    • Zhang M, Mal N, Kiedrowski M, Chacko M, Askari AT, Popovic ZB, Koc ON, Penn MS: SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myo-cytes after myocardial infarction. FASEB J 2007; 21:3197-3207. (Pubitemid 47565538)
    • (2007) FASEB Journal , vol.21 , Issue.12 , pp. 3197-3207
    • Zhang, M.1    Mal, N.2    Kiedrowski, M.3    Chacko, M.4    Askari, A.T.5    Popovic, Z.B.6    Koc, O.N.7    Penn, M.S.8
  • 46
    • 39849097361 scopus 로고    scopus 로고
    • Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance
    • Cheng Z, Ou L, Zhou X, Li F, Jia X, Zhang Y, Liu X, Li Y, Ward CA, Melo L G, Kong D: Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Mol Ther 2008; 16:571-579.
    • (2008) Mol Ther , vol.16 , pp. 571-579
    • Cheng, Z.1    Ou, L.2    Zhou, X.3    Li, F.4    Jia, X.5    Zhang, Y.6    Liu, X.7    Li, Y.8    Ward, C.A.9    Melo, L.G.10    Kong, D.11
  • 48
    • 0034971110 scopus 로고    scopus 로고
    • Cardiomyocyte grafting for cardiac repair: Graft cell death and anti-death strategies
    • Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE: Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 2001; 33: 907-921.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 907-921
    • Zhang, M.1    Methot, D.2    Poppa, V.3    Fujio, Y.4    Walsh, K.5    Murry, C.E.6
  • 49
    • 1142297598 scopus 로고    scopus 로고
    • New concepts in reactive oxygen species and cardiovascular reperfusion physiology
    • Becker LB: New concepts in reactive oxygen species and cardiovascular reperfusion physiology. Cardiovasc Res 2004; 61:461-470.
    • (2004) Cardiovasc Res , vol.61 , pp. 461-470
    • Becker, L.B.1
  • 51
    • 17644388462 scopus 로고    scopus 로고
    • Role of c5a in inflammatory responses
    • Guo RF, Ward PA: Role of c5a in inflamma-tor y responses. Annu Rev Immunol 2005; 23: 821-852.
    • (2005) Annu Rev Immunol , vol.23 , pp. 821-852
    • Guo, R.F.1    Ward, P.A.2
  • 55
    • 60649098283 scopus 로고    scopus 로고
    • Intracoronary administration of bone marrow-derived progenitor cells improves left ventricular function in p at ients at r isk for adverse remodel i ng after acute ST-segment elevation myocardial infarction: Results of the Reinfusion of Enriched Progenitor cells and Infarct Remodeling in Acute Myocardial Infarction study (REPAIR-AMI) cardiac magnetic resonance imaging substudy
    • Dill T, Schächinger V, Rolf A, Möllmann S, Thiele H, Tillmanns H, Assmus B, Dimmeler S, Zeiher AM, Hamm C: Intracoronary administration of bone marrow-derived progenitor cells improves left ventricular function in p at ients at r isk for adverse remodel i ng after acute ST-segment elevation myocardial infarction: results of the Reinfusion of Enriched Progenitor cells And Infarct Remodeling in Acute Myocardial Infarction study (REPAIR-AMI) cardiac magnetic resonance imaging substudy. Am Heart J 2009; 157: 541-547.
    • (2009) Am Heart J , vol.157 , pp. 541-547
    • Dill, T.1    Schächinger, V.2    Rolf, A.3    Möllmann, S.4    Thiele, H.5    Tillmanns, H.6    Assmus, B.7    Dimmeler, S.8    Zeiher, A.M.9    Hamm, C.10
  • 58
    • 1642318602 scopus 로고    scopus 로고
    • Subgroup analysis in clinical trials
    • Cook DI, Gebski VJ, Keech AC: Subgroup analysis in clinical trials. Med J Aust 2004; 180 : 289-291.
    • (2004) Med J Aust , vol.180 , pp. 289-291
    • Cook, D.I.1    Gebski, V.J.2    Keech, A.C.3
  • 60
    • 67349149118 scopus 로고    scopus 로고
    • Pluripotent stem cells
    • Verfaillie C: Pluripotent stem cells. Transfus Clin Biol 2009; 16: 65-69.
    • (2009) Transfus Clin Biol , vol.16 , pp. 65-69
    • Verfaillie, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.