-
1
-
-
77957128233
-
ErbB3 expression promotes tumorgenesis in pancreatic adenocarcinoma
-
Liles JS, Arnoletti JP, Tzeng CW, Howard JH, Kossenkov AV, Kulesza P, et al. ErbB3 expression promotes tumorgenesis in pancreatic adenocarcinoma. Cancer Biol Ther 2010; 10:555-63.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 555-563
-
-
Liles, J.S.1
Arnoletti, J.P.2
Tzeng, C.W.3
Howard, J.H.4
Kossenkov, A.V.5
Kulesza, P.6
-
2
-
-
0032529048
-
Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein
-
Kim HH, Vijapurkar U, Hellyer NJ, Bravo D, Koland JG. Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein. Biochem J 1998; 334:189-95. (Pubitemid 28420988)
-
(1998)
Biochemical Journal
, vol.334
, Issue.1
, pp. 189-195
-
-
Kim, H.-H.1
Vijapurkar, U.2
Hellyer, N.J.3
Bravo, D.4
Koland, J.G.5
-
3
-
-
33745727112
-
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
-
Wang SE, Narasanna A, Perez-Torres M, Xiang B, Wu FY, Yang S, et al. HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell 2006; 10:25-38.
-
(2006)
Cancer Cell
, vol.10
, pp. 25-38
-
-
Wang, S.E.1
Narasanna, A.2
Perez-Torres, M.3
Xiang, B.4
Wu, F.Y.5
Yang, S.6
-
4
-
-
0028302018
-
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
-
Soltoff SP, Carraway KL, 3rd, Prigent SA, Gullick WG, Cantley LC. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 1994; 14:3550-8.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway III, K.L.2
Prigent, S.A.3
Gullick, W.G.4
Cantley, L.C.5
-
5
-
-
0037335568
-
Stress and radiation-induced activation of multiple intracellular signaling pathways
-
Dent P, Yacoub A, Contessa J, Caron R, Amorino G, Valerie K, et al. Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiat Res 2003; 159:283-300.
-
(2003)
Radiat Res
, vol.159
, pp. 283-300
-
-
Dent, P.1
Yacoub, A.2
Contessa, J.3
Caron, R.4
Amorino, G.5
Valerie, K.6
-
6
-
-
23044480581
-
ErbB3 expression predicts tumor cell radio-sensitization induced by Hsp90 inhibition
-
Dote H, Cerna D, Burgan WE, Camphausen K, Tofilon PJ. ErbB3 expression predicts tumor cell radio-sensitization induced by Hsp90 inhibition. Cancer Res 2005; 65:6967-75.
-
(2005)
Cancer Res
, vol.65
, pp. 6967-6975
-
-
Dote, H.1
Cerna, D.2
Burgan, W.E.3
Camphausen, K.4
Tofilon, P.J.5
-
7
-
-
0028120910
-
Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members
-
Fedi P, Pierce JH, di Fiore PP, Kraus MH. Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. Mol Cell Biol 1994; 14:492-500. (Pubitemid 24013111)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.1
, pp. 492-500
-
-
Fedi, P.1
Pierce, J.H.2
Di Fiore, P.P.3
Kraus, M.H.4
-
8
-
-
33846552656
-
Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3
-
Sergina NV, Rausch M, Wang D, Blair J, Hann B, Shokat KM, et al. Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3. Nature 2007; 445:437-41.
-
(2007)
Nature
, vol.445
, pp. 437-441
-
-
Sergina, N.V.1
Rausch, M.2
Wang, D.3
Blair, J.4
Hann, B.5
Shokat, K.M.6
-
9
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007; 316:1039-43.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
10
-
-
77952338791
-
ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
-
Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proc Natl Acad Sci USA 2010; 107:7692-7.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7692-7697
-
-
Shi, F.1
Telesco, S.E.2
Liu, Y.3
Radhakrishnan, R.4
Lemmon, M.A.5
-
11
-
-
0028168569
-
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity
-
Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KLr. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci USA 1994; 91:8132-6.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8132-8136
-
-
Guy, P.M.1
Platko, J.V.2
Cantley, L.C.3
Cerione, R.A.4
Carraway, K.Lr.5
-
12
-
-
0030973939
-
Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein
-
Sierke SL, Cheng K, Kim HH, Koland JG. Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein. Biochem J 1997; 322:757-63. (Pubitemid 27135621)
-
(1997)
Biochemical Journal
, vol.322
, Issue.3
, pp. 757-763
-
-
Sierke, S.L.1
Cheng, K.2
Kim, H.-H.3
Koland, J.G.4
-
13
-
-
76049128717
-
Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3
-
Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J. Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3. Proc Natl Acad Sci USA 2009; 106:21608-13.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21608-21613
-
-
Jura, N.1
Shan, Y.2
Cao, X.3
Shaw, D.E.4
Kuriyan, J.5
-
14
-
-
33745002702
-
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
-
DOI 10.1016/j.cell.2006.05.013, PII S0092867406005848
-
Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 2006; 125:1137-49. (Pubitemid 43866200)
-
(2006)
Cell
, vol.125
, Issue.6
, pp. 1137-1149
-
-
Zhang, X.1
Gureasko, J.2
Shen, K.3
Cole, P.A.4
Kuriyan, J.5
-
15
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009; 324:1457-61.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
-
16
-
-
46249092188
-
Pancreatic cancer - Is the wall crumbling?
-
Chua YJ, Zalcberg JR. Pancreatic cancer - is the wall crumbling? Ann Oncol 2008; 19:1224-30.
-
(2008)
Ann Oncol
, vol.19
, pp. 1224-1230
-
-
Chua, Y.J.1
Zalcberg, J.R.2
-
17
-
-
34548251394
-
ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib
-
Frolov A, Schuller K, Tzeng CW, Cannon EE, Ku BC, Howard JH, et al. ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib. Cancer Biol Ther 2007; 6:548-54.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 548-554
-
-
Frolov, A.1
Schuller, K.2
Tzeng, C.W.3
Cannon, E.E.4
Ku, B.C.5
Howard, J.H.6
-
18
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK, Arnold L, Boman B, Cunningham A, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997; 57:4838-48.
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
Arnold, L.4
Boman, B.5
Cunningham, A.6
-
19
-
-
0035476866
-
The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer
-
Rusnak DW, Affleck K, Cockerill SG, Stubberfield C, Harris R, Page M, et al. The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Res 2001; 61:7196-203.
-
(2001)
Cancer Res
, vol.61
, pp. 7196-7203
-
-
Rusnak, D.W.1
Affleck, K.2
Cockerill, S.G.3
Stubberfield, C.4
Harris, R.5
Page, M.6
-
20
-
-
19744365702
-
A small molecule-kinase interaction map for clinical kinase inhibitors
-
Fabian MA, Biggs WH, 3rd, Treiber DK, Atteridge CE, Azimioara MD, Benedetti MG, et al. A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 2005; 23:329-36.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 329-336
-
-
Fabian, M.A.1
Biggs III, W.H.2
Treiber, D.K.3
Atteridge, C.E.4
Azimioara, M.D.5
Benedetti, M.G.6
-
21
-
-
33847061736
-
Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression
-
DOI 10.1158/0008-5472.CAN-06-3493
-
Schaefer G, Shao L, Totpal K, Akita RW. Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression. Cancer Res 2007; 67:1228-38. (Pubitemid 46270782)
-
(2007)
Cancer Research
, vol.67
, Issue.3
, pp. 1228-1238
-
-
Schaefer, G.1
Shao, L.2
Totpal, K.3
Akita, R.W.4
-
22
-
-
10944226719
-
Simultaneous determination of OSI-774 and its major metabolite OSI-420 in human plasma by using HPLC with UV detection
-
Zhang W, Siu LL, Moore MJ, Chen EX. Simultaneous determination of OSI-774 and its major metabolite OSI-420 in human plasma by using HPLC with UV detection. J Chromatogr B Analyt Technol Biomed Life Sci 2005; 814:143-7.
-
(2005)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.814
, pp. 143-147
-
-
Zhang, W.1
Siu, L.L.2
Moore, M.J.3
Chen, E.X.4
-
23
-
-
32944469063
-
Evaluation of the absolute oral bioavailability and bioequivalence of erlotinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in a randomized, crossover study in healthy subjects
-
Frohna P, Lu J, Eppler S, Hamilton M, Wolf J, Rakhit A, et al. Evaluation of the absolute oral bioavailability and bioequivalence of erlotinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in a randomized, crossover study in healthy subjects. J Clin Pharmacol 2006; 46:282-90.
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 282-290
-
-
Frohna, P.1
Lu, J.2
Eppler, S.3
Hamilton, M.4
Wolf, J.5
Rakhit, A.6
-
24
-
-
0035476803
-
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
-
Moasser MM, Basso A, Averbuch SD, Rosen N. The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res 2001; 61:7184-8. (Pubitemid 32946513)
-
(2001)
Cancer Research
, vol.61
, Issue.19
, pp. 7184-7188
-
-
Moasser, M.M.1
Basso, A.2
Averbuch, S.D.3
Rosen, N.4
-
25
-
-
0035893560
-
Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
-
Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, Arteaga CL. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res 2001; 61:8887-95.
-
(2001)
Cancer Res
, vol.61
, pp. 8887-8895
-
-
Moulder, S.L.1
Yakes, F.M.2
Muthuswamy, S.K.3
Bianco, R.4
Simpson, J.F.5
Arteaga, C.L.6
-
26
-
-
0035892346
-
ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression
-
DOI 10.1002/ijc.1557
-
Anderson NG, Ahmad T, Chan K, Dobson R, Bundred NJ. ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression. Int J Cancer 2001; 94:774-82. (Pubitemid 33032823)
-
(2001)
International Journal of Cancer
, vol.94
, Issue.6
, pp. 774-782
-
-
Anderson, N.G.1
Ahmad, T.2
Chan, K.3
Dobson, R.4
Bundred, N.J.5
-
27
-
-
24644445676
-
Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
-
Cappuzzo F, Varella-Garcia M, Shigematsu H, Domenichini I, Bartolini S, Ceresoli GL, et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients. J Clin Oncol 2005; 23:5007-18.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5007-5018
-
-
Cappuzzo, F.1
Varella-Garcia, M.2
Shigematsu, H.3
Domenichini, I.4
Bartolini, S.5
Ceresoli, G.L.6
-
28
-
-
24044436190
-
Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis
-
Clayton AH, Walker F, Orchard SG, Henderson C, Fuchs D, Rothacker J, et al. Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis. J Biol Chem 2005; 280:30392-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 30392-30399
-
-
Clayton, A.H.1
Walker, F.2
Orchard, S.G.3
Henderson, C.4
Fuchs, D.5
Rothacker, J.6
|