Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis

Upsala Journal of Medical Sciences

Volumn 114, Issue 3, 2009, Pages 140-148

  Potu, Bhagath K ^a   Rao, Muddanna S ^a   Nampurath, Gopalan K ^b   Chamallamudi, Mallikarjuna R ^b   Prasad, Keerthana ^c   Nayak, Soubhagya R ^d   Dharmavarapu, Praveen K ^a   Kedage, Vivekananda ^a   Bhat, Kumar M R ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

^b MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^c MANIPAL UNIVERSITY   (India)

^d KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Antiosteoporotic agents; Ovariectomy; Phytogenic steroid; Postmenopausal osteoporosis

Indexed keywords

ALKALINE PHOSPHATASE; ALKANE; NAPHTHA; PLANT EXTRACT;

ANIMAL; ARTICLE; BONE; BONE DEVELOPMENT; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CISSUS; DRUG EFFECT; ENZYMOLOGY; EVIDENCE BASED MEDICINE; FEMALE; METABOLISM; OSTEOPOROSIS; OVARIECTOMY; RAT; WISTAR RAT;

ALKALINE PHOSPHATASE; ALKANES; ANIMALS; BONE AND BONES; BONE DEVELOPMENT; CISSUS; EVIDENCE-BASED MEDICINE; FEMALE; OSTEOPOROSIS; OVARIECTOMY; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 77957094391     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.1080/03009730902891784     Document Type: Article

References (50)

1. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. J Am Med Assoc. 2002;288:321-333
2. Wronsky TJ, Dann LM, Qi H, Yen CF. Skeletal effects of withdrawal of estrogen and diphosphonate treatment in ovariectomized rats. Calcif Tiss Internat. 1993;53:210-216
3. Canalis H, McCarthy T, Centrella M. Growth factors and the regulation on bone remodeling. J Clin Invest. 1998;81: 277-281
4. Gorman C, Park A. The truth about hormones. Time. 2002 Jul 22;160(4):32-37
5. Pongboonrod S. Mai Thed Mung Muang Thai. Bangkok: Kaeseam-bunnakit Printing, Thailand, 1995. p. 428-429
6. Ramamurthy B, Seshadri T. Carotene content of Vitis quadrangularis. Proceedings of the Indian Academy of Sciences. 1939;9:121-127
7. Das PK, Sanyal AK. Studies on Cissus quadrangularis linn, acetylcholine like action of the total extract. Indian J Med Res. 1964;52:63-67
8. Chopra SS, Patel MR, Awadhiya RP. Studies of Cissus Quadrangularis in experimental fracture repair: a histopathological study. Indian J Med Res. 1976;64:1365-1368
9. Oliver-Bever B. Medicinal plants in tropical West Africa. II. Plants acting on the nervous system. J Ethnopharmacol. 1983;7:1-93.
10. Oliver-Bever B. Medicinal plants in tropical West Africa. III. Anti-infection therapy with higher plants. J Ethnopharmacol. 1983;9:1-83.
11. Singh SP, Mishra N, Dixit KS, Singh N, Kohli RP. An experimental study of analgesic activity of Cissus quadrangularis. Indian J Pharmacol. 1984;79:162-163
12. Chidambara Murthy KN, Vanitha A, Mahadeva Swamy M, Ravishankar GA. Antioxidant and antimicrobial activity of Cissus quadrangularis L. J Med Food. 2003;6:99-105.
13. Shirwaikar A, Khan S, Malini S. Antiosteoporotic effect of ethanol extract of Cissus quadrangularis Linn. on ovariectomized rat. J Ethnopharmacol. 2003;89:245-250
14. Jainu M, Mohan KV, Shyamala Devi CS. Gastroprotective effect of Cissus quadrangularis extract in rats with experimentally induced ulcer. Indian J Med Res. 2006;23:799-806. (Pubitemid 44269947)
15. Jainu M, Devi CS. Gastroprotective action of Cissus quadrangularis extract against NSAID induced gastric ulcer: role of proinflammatory cytokines and oxidative damage. Chem Biol Interact. 2006;161:262-270
16. Jainu M, Mohan KV, Devi CS. Protective effect of Cissus quadrangularis on neutrophil mediated tissue injury induced by aspirin in rats. J Ethnopharmacol. 2006;104:302-305
17. Singh G, Rawat P, Maurya R. Constituents of Cissus quadrangularis. Nat Prod Res. 2007;21:522-528
18. Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesityinduced oxidative stress. Lipids Health Dis. 2007;6:4.
19. Bah S, Jager AK, Adsersen A, Diallo D, Paulsen BS. Antiplasmodial and GABA (A)-benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa. J Ethnopharmacol. 2007;110:451-457
20. Panthong A, Supraditaporn W, Kanjanapothi D, Taesotikul T, Reutrakul V. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. J Ethnopharmacol. 2007;110:264-270
21. Oben JE, Ngondi JL, Momo CN, Agbor GA, Sobgui CS. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis. 2008;7:12.
22. Jain A, Dixit J, Prakash D. Modulatory effects of Cissus quadrangularis on periodontal regeneration by bovine-derived hydroxyapatite in intrabony defects: exploratory clinical trial. J Int Acad Periodontol. 2008;10:59-65.
23. Potu BK, Rao MS, Swamy NVB, Kutty GN. Cissus quadrangularis plant extract enhances the ossification of fetal bones. Pharmacologyonline. 2007;1:63-70.
24. Rao MS, Potu BK, Swamy NVB, Kutty GN. Cissus Quadrangularis plant extract enhances the development of cortical bone and trabeculae in the fetal femur. Pharmacologyonline. 2007;3:190-202.
25. Potu BK, Rao MS, Kutty GN, Bhat MRK, Chamallamudi MR, Nayak SR. Petroleum ether extract of Cissus quadrangularis (Linn) stimulates the growth of fetal bone during intra uterine developmental period: a morphometric analysis. Clinics. 2008;63:815-820
26. Ghosh MN. Fundamentals of experimental pharmacology. 2nd ed. Calcutta, India: Scientific Book Agency; 1984. p. 153-157
27. Reddy NP, Lakshmana M, Udupa UV. Antiosteoporotic activity of OST-6 (Osteocare), a herbomineral preparation in calcium deficient ovariectomized rats. Phytother Res. 2004;18:25-29
28. McLean I, Nakane P. Periodate-lysine-paraformaldehyde fixative: a new fixative for immunoelectron microscopy. J Histochem Cytochem. 1974;22:1077-1083
29. Mori S, Sawai T, Teshima T, Kyogoku M. A new decalcifying technique for immunohistochemical studies of calcified tissue, especially applicable to cell surface marker demonstration. J Histochem Cytochem. 1988;36:111-114
30. Bourque W, Gross M, Hall B. A histological processing technique that preserves the integrity of calcified tissues (bone, enamel), yolky amphibian embryos, and growth factor antigens in skeletal tissue. J Histochem Cytochem. 1993;41: 1429-1434
31. Yoshiki S, Umeda T, Kurahashi Y. An effective reactivation of alkaline phosphatase in hard tissues completely decalcified for light and electron microscopy. Histochemie. 1972;29: 296-304.
32. Miao D, Scutt A. Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo. BMC Musculoskelet Disord. 2002;3:16.
33. Prasad A, Nayak PK. Color image analysis to grade shades of a color and its application to quantify stained tissues. In: 4th Kuala Lumpur International Conference on Biomedical Engineering 2008. IFMBE Proceedings. Vol.21. Berlin; Heidelberg: Springer. 2008. p. 154-157
34. Harada SI, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature. 2003;423:349-355
35. Nelson HD, Humphrey LL, Nygren P, Teutsch SM, Allan JD. Postmenopausal hormone replacement therapy: scientific review. JAMA. 2002;288:872-881
36. Davison S, Davis SR. Hormone replacement therapy: current controversies. Clin Endocrinol. 2003;58:249-261
37. Kalu DN, Liu CC, Salerno E, Hollis B, Echon R, Ray M. Skeletal response of ovariectomized rats to low and high doses of 17 b estrodiol. Bone Miner. 1991;14:175-187
38. Rudman D, Feller AG, Nagraj HS, Gergans GA, Lalitha PY, Goldberg AF, et al. Effects of human growth hormone in men over 60 years old. N Engl J Med. 1990;323:1-6.
39. Arjmandi BH, Liu CC, Yu S, Kalu DN. The effect of growth hormone on trabecular bone loss, osteoclasts, osteoblasts, and their marrow progenitors (abstract). J Bone Min Res. 1994;9:S382.
40. Turner RT, Evans GL, Wakley GK. Reduced chondroclast differentiation results in increased cancellous bone volume in estrogen-treated growing rats. Endocrinology. 1994;134: 461-466
41. Rahnama M, Swiatkowski W. Effect of ovariectomy on biochemical markers of bone turnover (ALP, ACP) and calcium content in rat mandible and teeth. Bull Vet Inst Pulawy. 2002;46:281-287
42. Sen SP. Studies on the active constituents of Cissus quadrangularis Wall. Curr Sci. 1966;35:317.
43. Bhutani KK, Kapoor R, Atal CK. Two unsymmetric tetracyclic triterpenoids from Cissus quadrangularis. Phytochemistry. 1984;23:407-410
44. Gupta MM, Verma RK. Unsymmetric tetracyclic triterpenoids from Cissus quadrangularis. Phytochemistry. 1990;29: 336-337
45. Mehta M, Kaur N, Bhutani KK. Determination of marker constituents from Cissus quadiangularis Linn. and their quantitation by HPTLC and HPLC. Phytochem Anal. 2001;12:91-95
46. Kausch AP, Horner HT. A comparison of calcium oxalate crystals isolated from callus cultures and their explant sources. Scan Electron Microsc. 1982;1:199-211.
47. Gupta MM, Verma RK. Lipid constituents of Cissus quadrangularis. Phytochemistry. 1991;30:875-878
48. Adesanya SA, Nia R, Maartin MT, Boukamcha N, Montagnac A, Pais M. Stilbene derivatives from Cissus quadrangularis. J Nat Prod. 1999;62:1694-1695
49. Pluemjai T, Saifah E. Constituents of Cissus quadrangularis Linn. Thai Journal of Pharmaceutical Sciences. 1986;11: 205-211
50. Bahram HA, Lee A, Bruce WH, Daxa A, Maria S, Peilin G, et al. Dietary soybean prevents bone loss in a ovariectomized rat model of Osteoporosis. J Nutr. 1996;126:161-167