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Volumn 51, Issue 9, 2010, Pages 1464-1471

Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells

Author keywords

3H FLT; 3H FMAU; Nucleoside metabolism; Nucleoside transport; Proliferation

Indexed keywords

1 (2 DEOXY 2 FLUORO BETA DEXTRO ARABINOFURANOSYL) 5 METHYLURACIL H 3; 3' DEOXY 3' FLUOROTHYMIDINE H 3; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; NUCLEOSIDE TRANSPORTER; RADIOPHARMACEUTICAL AGENT; THYMIDINE H 3; TRACER; UNCLASSIFIED DRUG; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 2'-FLUORO-5-METHYLARABINOSYLURACIL; 3' FLUOROTHYMIDINE; CLEVUDINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; THYMIDINE; TRITIUM; URACIL ARABINOSIDE;

EID: 77957084543     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.110.076794     Document Type: Article
Times cited : (41)

References (30)
  • 1
    • 0042631398 scopus 로고    scopus 로고
    • Positron emission tomography in non-small-cell lung cancer: Prediction of response to chemotherapy by quantitative assessment of glucose use
    • DOI 10.1200/JCO.2003.12.004
    • Weber WA, Petersen V, Schmidt B, et al. Positron emission tomography in non-small- cell lung cancer: prediction of response to chemotherapy by quantitative assessment of glucose use. J Clin Oncol. 2003;21:2651-2657. (Pubitemid 46606307)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.14 , pp. 2651-2657
    • Weber, W.A.1    Petersen, V.2    Schmidt, B.3    Tyndale-Hines, L.4    Link, T.5    Peschel, C.6    Schwaiger, M.7
  • 2
    • 0036987011 scopus 로고    scopus 로고
    • Molecular imaging of regional brain tumor biology
    • Spence AM, Muzi M, Krohn KA. Molecular imaging of regional brain tumor biology. J Cell Biochem Suppl. 2002;39:25-35.
    • (2002) J Cell Biochem Suppl , vol.39 , pp. 25-35
    • Spence, A.M.1    Muzi, M.2    Krohn, K.A.3
  • 3
    • 0034743498 scopus 로고    scopus 로고
    • Imaging cellular proliferation as a measure of response to therapy
    • Krohn KA, Mankoff DA, Eary JF. Imaging cellular proliferation as a measure of response to therapy. J Clin Pharmacol. 2001;41(suppl):96S-103S.
    • (2001) J Clin Pharmacol , vol.41 , Issue.SUPPL.
    • Krohn, K.A.1    Mankoff, D.A.2    Eary, J.F.3
  • 6
    • 0142212381 scopus 로고    scopus 로고
    • 18F-FLT and thymidine analogs: Promise and pitfalls
    • 18F-FLT and thymidine analogs: promise and pitfalls. J Nucl Med. 2003;44:1432-1434.
    • (2003) J Nucl Med , vol.44 , pp. 1432-1434
    • Shields, A.F.1
  • 8
    • 0036732034 scopus 로고    scopus 로고
    • Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells
    • Rasey JS, Grierson JR, Wiens LW, Kolb PD, Schwartz JL. Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells. J Nucl Med. 2002;43:1210-1217.
    • (2002) J Nucl Med , vol.43 , pp. 1210-1217
    • Rasey, J.S.1    Grierson, J.R.2    Wiens, L.W.3    Kolb, P.D.4    Schwartz, J.L.5
  • 9
    • 33748992895 scopus 로고    scopus 로고
    • Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography
    • Perumal M, Pillai RG, Barthel H, et al. Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography. Cancer Res. 2006;66: 8558-8564.
    • (2006) Cancer Res , vol.66 , pp. 8558-8564
    • Perumal, M.1    Pillai, R.G.2    Barthel, H.3
  • 10
    • 54349124554 scopus 로고    scopus 로고
    • The role of human nucleoside transporters in uptake of 3′-deoxy-3′-fluorothymidine
    • Paproski RJ, Ng AM, Yao SY, Graham K, Young JD, Cass CE. The role of human nucleoside transporters in uptake of 3′-deoxy-3′- fluorothymidine. Mol Pharmacol. 2008;74:1372-1380.
    • (2008) Mol Pharmacol , vol.74 , pp. 1372-1380
    • Paproski, R.J.1    Ng, A.M.2    Yao, S.Y.3    Graham, K.4    Young, J.D.5    Cass, C.E.6
  • 11
    • 0035661677 scopus 로고    scopus 로고
    • Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine
    • Szkotak AJ, Ng AM, Sawicka J, et al. Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine. Am J Physiol Cell Physiol. 2001;281:C1991-C2002.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Szkotak, A.J.1    Ng, A.M.2    Sawicka, J.3
  • 12
    • 0034708596 scopus 로고    scopus 로고
    • Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells: Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine
    • Ward JL, Sherali A, Mo ZP, Tse CM. Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells: Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine. J Biol Chem. 2000;275:8375-8381.
    • (2000) J Biol Chem , vol.275 , pp. 8375-8381
    • Ward, J.L.1    Sherali, A.2    Mo, Z.P.3    Tse, C.M.4
  • 14
    • 0028362987 scopus 로고
    • Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein
    • Huang QQ, Yao SY, Ritzel MW, Paterson AR, Cass CE, Young JD. Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J Biol Chem. 1994;269:17757-17760.
    • (1994) J Biol Chem , vol.269 , pp. 17757-17760
    • Huang, Q.Q.1    Yao, S.Y.2    Ritzel, M.W.3    Paterson, A.R.4    Cass, C.E.5    Young, J.D.6
  • 15
    • 0032467665 scopus 로고    scopus 로고
    • Recent advances in the molecular biology of nucleoside transporters of mammalian cells
    • Cass CE, Young JD, Baldwin SA. Recent advances in the molecular biology of nucleoside transporters of mammalian cells. Biochem Cell Biol. 1998;76:761-770.
    • (1998) Biochem Cell Biol , vol.76 , pp. 761-770
    • Cass, C.E.1    Young, J.D.2    Baldwin, S.A.3
  • 16
    • 0345688175 scopus 로고    scopus 로고
    • Nucleoside anticancer drugs: The role of nucleoside transporters in resistance to cancer chemotherapy
    • Damaraju VL, Damaraju S, Young JD, et al. Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy. Oncogene. 2003;22:7524-7536.
    • (2003) Oncogene , vol.22 , pp. 7524-7536
    • Damaraju, V.L.1    Damaraju, S.2    Young, J.D.3
  • 18
    • 0026509422 scopus 로고
    • Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3′-fluoro- 3′-deoxythymidine and 3′-azido-3′-deoxythymidine
    • Kong XB, Zhu QY, Vidal PM, et al. Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3′-fluoro-3′-deoxythymidine and 3′-azido-3′-deoxythymidine. Antimicrob Agents Chemother. 1992;36:808-818.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 808-818
    • Kong, X.B.1    Zhu, Q.Y.2    Vidal, P.M.3
  • 19
    • 0033748178 scopus 로고    scopus 로고
    • Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters
    • Patil SD, Ngo LY, Unadkat JD. Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters. Cancer Chemother Pharmacol. 2000;46:394-402.
    • (2000) Cancer Chemother Pharmacol , vol.46 , pp. 394-402
    • Patil, S.D.1    Ngo, L.Y.2    Unadkat, J.D.3
  • 20
    • 1542681635 scopus 로고    scopus 로고
    • Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs
    • Schwartz JL, Tamura Y, Jordan R, Grierson JR, Krohn KA. Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs. J Nucl Med. 2003;44:2027-2032.
    • (2003) J Nucl Med , vol.44 , pp. 2027-2032
    • Schwartz, J.L.1    Tamura, Y.2    Jordan, R.3    Grierson, J.R.4    Krohn, K.A.5
  • 21
    • 1242331023 scopus 로고    scopus 로고
    • Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep
    • SenGupta DJ, Unadkat JD. Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep. Biochem Pharmacol. 2004;67:453-458.
    • (2004) Biochem Pharmacol , vol.67 , pp. 453-458
    • SenGupta, D.J.1    Unadkat, J.D.2
  • 22
    • 0026326548 scopus 로고
    • Comparative pharmacology of the nitrobenzylthioguanosine-sensitive and -resistant nucleoside transport mechanisms of Ehrlich ascites tumor cells
    • Hammond JR. Comparative pharmacology of the nitrobenzylthioguanosine- sensitive and -resistant nucleoside transport mechanisms of Ehrlich ascites tumor cells. J Pharmacol Exp Ther. 1991;259:799-807.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 799-807
    • Hammond, J.R.1
  • 23
    • 0021953877 scopus 로고
    • Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma
    • Wiley JS, Taupin J, Jamieson GP, Snook M, Sawyer WH, Finch LR. Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma. J Clin Invest. 1985;75:632-642.
    • (1985) J Clin Invest , vol.75 , pp. 632-642
    • Wiley, J.S.1    Taupin, J.2    Jamieson, G.P.3    Snook, M.4    Sawyer, W.H.5    Finch, L.R.6
  • 24
    • 18744438445 scopus 로고    scopus 로고
    • Nucleoside transporters of mammalian cells
    • Cass CE, Young JD, Baldwin SA, et al. Nucleoside transporters of mammalian cells. Pharm Biotechnol. 1999;12:313-352.
    • (1999) Pharm Biotechnol , vol.12 , pp. 313-352
    • Cass, C.E.1    Young, J.D.2    Baldwin, S.A.3
  • 25
    • 0034995844 scopus 로고    scopus 로고
    • The ENT family of eukaryote nucleoside and nucleobase transporters: Recent advances in the investigation of structure/function relationships and the identification of novel isoforms
    • Hyde RJ, Cass CE, Young JD, Baldwin SA. The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol Membr Biol. 2001;18:53-63.
    • (2001) Mol Membr Biol , vol.18 , pp. 53-63
    • Hyde, R.J.1    Cass, C.E.2    Young, J.D.3    Baldwin, S.A.4
  • 26
    • 1442302331 scopus 로고    scopus 로고
    • Mammalian nucleoside transporters
    • Kong W, Engel K, Wang J. Mammalian nucleoside transporters. Curr Drug Metab. 2004;5:63-84.
    • (2004) Curr Drug Metab , vol.5 , pp. 63-84
    • Kong, W.1    Engel, K.2    Wang, J.3
  • 27
    • 0008817735 scopus 로고    scopus 로고
    • Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells
    • del Santo B, Valdes R, Mata J, Felipe A, Casado FJ, Pastor-Anglada M. Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells. Hepatology. 1998;28:1504-1511.
    • (1998) Hepatology , vol.28 , pp. 1504-1511
    • Del Santo, B.1    Valdes, R.2    Mata, J.3    Felipe, A.4    Casado, F.J.5    Pastor-Anglada, M.6
  • 28
    • 0034854829 scopus 로고    scopus 로고
    • Macrophages require different nucleoside transport systems for proliferation and activation
    • Soler C, Garcia-Manteiga J, Valdes R, et al. Macrophages require different nucleoside transport systems for proliferation and activation. FASEB J. 2001;15:1979-1988.
    • (2001) FASEB J , vol.15 , pp. 1979-1988
    • Soler, C.1    Garcia-Manteiga, J.2    Valdes, R.3
  • 30
    • 0029888564 scopus 로고    scopus 로고
    • Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2′-deoxy-2′-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity
    • Wang J, Eriksson S. Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2′-deoxy-2′-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity. Antimicrob Agents Chemother. 1996;40:1555-1557.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1555-1557
    • Wang, J.1    Eriksson, S.2


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