A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo

Neuro-Oncology

Volumn 12, Issue 6, 2010, Pages 580-594

  Yu, Litian ^a,b,c   Baxter, Patricia A ^b   Voicu, Horatiu ^b   Gurusiddappa, Sivashankarappa ^b   Zhao, Yijue ^b   Adesina, Adekunle ^b   Man, Tsz Kwong ^b   Shu, Qin ^a,b   Zhang, Yu Jing ^a,b   Zhao, Xiu Mei ^a,b   Su, Jack M ^b   Perlaky, Lazlo ^b   Dauser, Robert ^b   Chintagumpala, Murali ^b   Lau, Ching C ^b   Blaney, Susan M ^b   Rao, Pulivarthi H ^b   Leung, Hon Chiu Eastwood ^b   Li, Xiao Nan ^a,b  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c FUWAI HOSPITAL   (China)

Author keywords

Cancer stem cell; Ependymoma; Gene expression profiling; Orthotopic xenograft model

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TUMOR; CANCER MODEL; CANCER STEM CELL; CASE REPORT; CELL LINE; CHILD; CHROMOSOME ABERRATION; EPENDYMOMA; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENOMICS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PRIMARY TUMOR; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SCID MOUSE; SPECTRAL KARYOTYPING; TUMOR CELL LINE; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; BRAIN NEOPLASMS; CHILD; EPENDYMOMA; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77957033364     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nop056     Document Type: Article

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