메뉴 건너뛰기




Volumn 60, Issue 1, 2010, Pages 29-39

The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors

Author keywords

Keratinocytes; Protein kinase C (PKC); Protein kinase D (PKD); Resveratrol; Skin; Transglutaminase

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; CALCITRIOL; CID 755673; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE D INHIBITOR; PROTEIN KINASE INHIBITOR; RESVERATROL; UNCLASSIFIED DRUG;

EID: 77957021002     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.07.015     Document Type: Article
Times cited : (13)

References (40)
  • 1
    • 0018862743 scopus 로고
    • Specific binding of phorbol ester tumor promoters to mouse skin
    • Delclos K.B., Nagle D.S., Blumberg P.M. Specific binding of phorbol ester tumor promoters to mouse skin. Cell 1980, 19:1025-1032.
    • (1980) Cell , vol.19 , pp. 1025-1032
    • Delclos, K.B.1    Nagle, D.S.2    Blumberg, P.M.3
  • 2
    • 0017191606 scopus 로고
    • Cutaneous chemical carcinogenesis: past, present, and future
    • Yuspa S.H., Hennings H., Saffiotti U. Cutaneous chemical carcinogenesis: past, present, and future. J Invest Dermatol 1976, 67(1):199-208.
    • (1976) J Invest Dermatol , vol.67 , Issue.1 , pp. 199-208
    • Yuspa, S.H.1    Hennings, H.2    Saffiotti, U.3
  • 3
    • 0018744412 scopus 로고
    • Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter
    • Goerttler K., Loehrke H., Schweizer J., Hesse B. Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter. Cancer Res 1979, 39(4):1293-1297.
    • (1979) Cancer Res , vol.39 , Issue.4 , pp. 1293-1297
    • Goerttler, K.1    Loehrke, H.2    Schweizer, J.3    Hesse, B.4
  • 4
    • 0037152680 scopus 로고    scopus 로고
    • Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis
    • Rubin H. Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis. Oncogene 2002, 21(48):7392-7411.
    • (2002) Oncogene , vol.21 , Issue.48 , pp. 7392-7411
    • Rubin, H.1
  • 5
    • 0032849088 scopus 로고    scopus 로고
    • New insights into the regulation of protein kinase C and novel phorbol ester receptors
    • Ron D., Kazanietz M.G. New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J 1999, 13(13):1658-1676.
    • (1999) FASEB J , vol.13 , Issue.13 , pp. 1658-1676
    • Ron, D.1    Kazanietz, M.G.2
  • 6
    • 0028881513 scopus 로고
    • Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase
    • Van Lint J., Sinnett-Smith J., Rozengurt E. Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J Biol Chem 1995, 270:1455-1461.
    • (1995) J Biol Chem , vol.270 , pp. 1455-1461
    • Van Lint, J.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 7
  • 8
    • 0037413711 scopus 로고    scopus 로고
    • Protein kinase D mediates a stress-induced NF-kB activation and survival pathway
    • Storz P., Toker A. Protein kinase D mediates a stress-induced NF-kB activation and survival pathway. EMBO J 2003, 22:109-120.
    • (2003) EMBO J , vol.22 , pp. 109-120
    • Storz, P.1    Toker, A.2
  • 9
    • 1642379541 scopus 로고    scopus 로고
    • Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling
    • Storz P., Döppler H., Toker A. Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling. Mol Cell Biol 2004, 24:2614-2626.
    • (2004) Mol Cell Biol , vol.24 , pp. 2614-2626
    • Storz, P.1    Döppler, H.2    Toker, A.3
  • 11
    • 4544315655 scopus 로고    scopus 로고
    • Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
    • Vega R.B., Harrison B.C., Meadows E., Roberts C.R., Papst P.J., Olson E.N., et al. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 2004, 24:8374-8385.
    • (2004) Mol Cell Biol , vol.24 , pp. 8374-8385
    • Vega, R.B.1    Harrison, B.C.2    Meadows, E.3    Roberts, C.R.4    Papst, P.J.5    Olson, E.N.6
  • 12
    • 0033524222 scopus 로고    scopus 로고
    • Protein kinase-Cμ expression correlates with enhanced keratinocyte proliferation in normal and neoplastic mouse epidermis and in cell culture
    • Rennecke J., Rehberger P.A., Fürstenberger G., Johannes F.-J., Stöhr M., Marks F., et al. Protein kinase-Cμ expression correlates with enhanced keratinocyte proliferation in normal and neoplastic mouse epidermis and in cell culture. Int J Cancer 1999, 80:98-103.
    • (1999) Int J Cancer , vol.80 , pp. 98-103
    • Rennecke, J.1    Rehberger, P.A.2    Fürstenberger, G.3    Johannes, F.-J.4    Stöhr, M.5    Marks, F.6
  • 13
    • 24344451280 scopus 로고    scopus 로고
    • Regulation of protein kinase D during differentiation and proliferation of primary mouse keratinocytes
    • Dodd M.E., Ristich V.L., Ray S., Lober R.M., Bollag W.B. Regulation of protein kinase D during differentiation and proliferation of primary mouse keratinocytes. J Invest Dermatol 2005, 125:294-306.
    • (2005) J Invest Dermatol , vol.125 , pp. 294-306
    • Dodd, M.E.1    Ristich, V.L.2    Ray, S.3    Lober, R.M.4    Bollag, W.B.5
  • 14
    • 33644871248 scopus 로고    scopus 로고
    • Protein kinase D distribution in normal human epidermis, basal cell carcinoma and psoriasis
    • Ristich V.L., Bowman P.H., Dodd M.E., Bollag W.B. Protein kinase D distribution in normal human epidermis, basal cell carcinoma and psoriasis. Br J Dermatol 2006, 154:586-593.
    • (2006) Br J Dermatol , vol.154 , pp. 586-593
    • Ristich, V.L.1    Bowman, P.H.2    Dodd, M.E.3    Bollag, W.B.4
  • 15
    • 0036082364 scopus 로고    scopus 로고
    • Putative conventional protein kinase C inhibitor Gödecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes
    • Shapiro B.A., Ray S., Jung E.M., Allred W.T., Bollag W.B. Putative conventional protein kinase C inhibitor Gödecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes. J Pharmacol Exp Ther 2002, 302:352-358.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 352-358
    • Shapiro, B.A.1    Ray, S.2    Jung, E.M.3    Allred, W.T.4    Bollag, W.B.5
  • 16
    • 40049111524 scopus 로고    scopus 로고
    • Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation
    • Ivanova P., Atanasova G., Poumay Y., Mitev V. Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation. Arch Dermatol Res 2008, 300:139-145.
    • (2008) Arch Dermatol Res , vol.300 , pp. 139-145
    • Ivanova, P.1    Atanasova, G.2    Poumay, Y.3    Mitev, V.4
  • 18
    • 0033015540 scopus 로고    scopus 로고
    • Phosphorylation-dependent protein kinase D activation
    • Waldron R.T., Iglesias T., Rozengurt E. Phosphorylation-dependent protein kinase D activation. Electrophoresis 1999, 20:382-390.
    • (1999) Electrophoresis , vol.20 , pp. 382-390
    • Waldron, R.T.1    Iglesias, T.2    Rozengurt, E.3
  • 19
    • 0027483340 scopus 로고
    • Effects of the selective protein kinase C inhibitor, Ro 31-7549, on the proliferation of cultured mouse epidermal keratinocytes
    • Bollag W.B., Ducote J., Harmon C.S. Effects of the selective protein kinase C inhibitor, Ro 31-7549, on the proliferation of cultured mouse epidermal keratinocytes. J Invest Dermatol 1993, 100:240-246.
    • (1993) J Invest Dermatol , vol.100 , pp. 240-246
    • Bollag, W.B.1    Ducote, J.2    Harmon, C.S.3
  • 20
    • 57749100261 scopus 로고    scopus 로고
    • Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone
    • Sharlow E.R., Giridhar K.V., La Valle C.R., Chen J., Leimgruber S., Barrett R., et al. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone. J Biol Chem 2008, 283:33516-33526.
    • (2008) J Biol Chem , vol.283 , pp. 33516-33526
    • Sharlow, E.R.1    Giridhar, K.V.2    La Valle, C.R.3    Chen, J.4    Leimgruber, S.5    Barrett, R.6
  • 21
    • 0033543570 scopus 로고    scopus 로고
    • Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/protein kinase Cμ
    • Matthews S.A., Rozengurt E., Cantrell D. Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/protein kinase Cμ. J Biol Chem 1999, 274:26543-26549.
    • (1999) J Biol Chem , vol.274 , pp. 26543-26549
    • Matthews, S.A.1    Rozengurt, E.2    Cantrell, D.3
  • 22
    • 73149089479 scopus 로고    scopus 로고
    • CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway
    • Torres-Marquez E., Sinnett-Smith J., Guha S., Kui R., Waldron R.T., Rey O., et al. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochem Biophys Res Commun 2010, 391:63-68.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 63-68
    • Torres-Marquez, E.1    Sinnett-Smith, J.2    Guha, S.3    Kui, R.4    Waldron, R.T.5    Rey, O.6
  • 23
    • 0025248571 scopus 로고
    • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells
    • Chijiwa T., Mishima A., Hagiwara M., Sano M., Hayashi K., Inoue T., et al. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 1990, 265(9):5267-5272.
    • (1990) J Biol Chem , vol.265 , Issue.9 , pp. 5267-5272
    • Chijiwa, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6
  • 24
    • 4143057185 scopus 로고    scopus 로고
    • Basic calcium phosphate crystals activate p44/42 MAPK signal transduction pathway via protein kinase Cmicro in human fibroblasts
    • Reuben P.M., Sun Y., Cheung H.S. Basic calcium phosphate crystals activate p44/42 MAPK signal transduction pathway via protein kinase Cmicro in human fibroblasts. J Biol Chem 2004, 279:35719-35725.
    • (2004) J Biol Chem , vol.279 , pp. 35719-35725
    • Reuben, P.M.1    Sun, Y.2    Cheung, H.S.3
  • 25
    • 0034333325 scopus 로고    scopus 로고
    • Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme phosphorylation
    • Stewart J.R., Christman K.L., O'Brian C.A. Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme phosphorylation. Biochem Pharmacol 2000, 60:1355-1359.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1355-1359
    • Stewart, J.R.1    Christman, K.L.2    O'Brian, C.A.3
  • 27
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors: Differentiation from protein kinase C isoenzymes
    • Gschwendt M., Dieterich S., Rennecke J., Kittstein W., Mueller H.J., Johannes F.-J. Inhibition of protein kinase C mu by various inhibitors: Differentiation from protein kinase C isoenzymes. FEBS Lett 1996, 392:77-80.
    • (1996) FEBS Lett , vol.392 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.J.5    Johannes, F.-J.6
  • 28
    • 0017105686 scopus 로고
    • Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate
    • Yuspa S.H., Ben T., Patterson E., Michael D., Elgjo K., Hennings H. Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate. Cancer Res 1976, 36:4062-4068.
    • (1976) Cancer Res , vol.36 , pp. 4062-4068
    • Yuspa, S.H.1    Ben, T.2    Patterson, E.3    Michael, D.4    Elgjo, K.5    Hennings, H.6
  • 29
    • 0027157640 scopus 로고
    • Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976
    • Martiny-Baron G., Kazanietz M.G., Mischak H., Blumberg P.M., Kochs G., Hug H., et al. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J Biol Chem 1993, 268(13):9194-9197.
    • (1993) J Biol Chem , vol.268 , Issue.13 , pp. 9194-9197
    • Martiny-Baron, G.1    Kazanietz, M.G.2    Mischak, H.3    Blumberg, P.M.4    Kochs, G.5    Hug, H.6
  • 30
    • 0030894024 scopus 로고    scopus 로고
    • Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form
    • Stempka L., Girod A., Muller H.J., Rincke G., Marks F., Gschwendt M., et al. Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form. J Biol Chem 1997, 272(10):6805-6811.
    • (1997) J Biol Chem , vol.272 , Issue.10 , pp. 6805-6811
    • Stempka, L.1    Girod, A.2    Muller, H.J.3    Rincke, G.4    Marks, F.5    Gschwendt, M.6
  • 31
    • 0032538539 scopus 로고    scopus 로고
    • Identification of in vivo phosphorylation sites required for protein kinase D activation
    • Iglesias T., Waldron R.T., Rozengurt E. Identification of in vivo phosphorylation sites required for protein kinase D activation. J Biol Chem 1998, 273:27662-27667.
    • (1998) J Biol Chem , vol.273 , pp. 27662-27667
    • Iglesias, T.1    Waldron, R.T.2    Rozengurt, E.3
  • 32
    • 0020006894 scopus 로고
    • The study of tumor promotion in a cell culture model for mouse skin-a tissue that exhibits multistage carcinogenesis in vivo
    • Yuspa S.H., Hennings H., Kulesz-Martin M., Lichti U. The study of tumor promotion in a cell culture model for mouse skin-a tissue that exhibits multistage carcinogenesis in vivo. Carcinog Compr Surv 1982, 7:217-230.
    • (1982) Carcinog Compr Surv , vol.7 , pp. 217-230
    • Yuspa, S.H.1    Hennings, H.2    Kulesz-Martin, M.3    Lichti, U.4
  • 33
    • 0015363933 scopus 로고
    • Early effects of 12-O-tetradecanoyl-phorbol-13-acetate on the incorporation of tritiated precursor into DNA and the thickness of the interfollicular epidermis, and their relation to tumor promotion in mouse skin
    • Raick A.N., Thumm K., Chivers R.B. Early effects of 12-O-tetradecanoyl-phorbol-13-acetate on the incorporation of tritiated precursor into DNA and the thickness of the interfollicular epidermis, and their relation to tumor promotion in mouse skin. Cancer Res 1972, 32:1562-1568.
    • (1972) Cancer Res , vol.32 , pp. 1562-1568
    • Raick, A.N.1    Thumm, K.2    Chivers, R.B.3
  • 34
    • 0020080466 scopus 로고
    • Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
    • Yuspa S.H., Ben T., Hennings H., Lichti U. Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res 1982, 42:2344-2349.
    • (1982) Cancer Res , vol.42 , pp. 2344-2349
    • Yuspa, S.H.1    Ben, T.2    Hennings, H.3    Lichti, U.4
  • 35
    • 0022382312 scopus 로고
    • Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding
    • Parkinson E.K. Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding. Br J Cancer 1985, 52(4):479-493.
    • (1985) Br J Cancer , vol.52 , Issue.4 , pp. 479-493
    • Parkinson, E.K.1
  • 36
    • 0031712658 scopus 로고    scopus 로고
    • Induction of reactive oxygen species without 8-hydroxydeoxyguanosine formation in DNA of initiated mouse keratinocytes treated with 12-O-tetradecanoylphorbol-13-acetate
    • Przybyszewski J., Box H.C., Kulesz-Martin M. Induction of reactive oxygen species without 8-hydroxydeoxyguanosine formation in DNA of initiated mouse keratinocytes treated with 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis 1998, 19:1467-1474.
    • (1998) Carcinogenesis , vol.19 , pp. 1467-1474
    • Przybyszewski, J.1    Box, H.C.2    Kulesz-Martin, M.3
  • 37
    • 17644388509 scopus 로고    scopus 로고
    • PKCeta is required for beta1gamma2/beta3gamma2- and PKD-mediated transport to the cell surface and the organization of the Golgi apparatus
    • Diaz Anel A.M., Malhotra V. PKCeta is required for beta1gamma2/beta3gamma2- and PKD-mediated transport to the cell surface and the organization of the Golgi apparatus. J Cell Biol 2005, 169(1):83-91.
    • (2005) J Cell Biol , vol.169 , Issue.1 , pp. 83-91
    • Diaz Anel, A.M.1    Malhotra, V.2
  • 38
    • 0031813150 scopus 로고    scopus 로고
    • Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the η and δ isoforms of protein kinase C
    • Ohba M., Ishino K., Kashiwagi M., Kawabe S., Chida K., Huh N., et al. Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the η and δ isoforms of protein kinase C. Mol Cell Biol 1998, 18:5199-5207.
    • (1998) Mol Cell Biol , vol.18 , pp. 5199-5207
    • Ohba, M.1    Ishino, K.2    Kashiwagi, M.3    Kawabe, S.4    Chida, K.5    Huh, N.6
  • 39
    • 33745306977 scopus 로고    scopus 로고
    • Tumor reversion: protein kinase A isozyme switching
    • Cho-Chung Y.S., Nesterova M.V. Tumor reversion: protein kinase A isozyme switching. Ann N Y Acad Sci 2005, 1058:76-86.
    • (2005) Ann N Y Acad Sci , vol.1058 , pp. 76-86
    • Cho-Chung, Y.S.1    Nesterova, M.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.