Intake of marine n-3 fatty acids during pregnancy and risk for epilepsy in the offspring: A population-based cohort study

Epilepsy Research

Volumn 91, Issue 2-3, 2010, Pages 267-272

  Sun, Yuelian ^a   Vestergaard, Mogens ^a   Christensen, Jakob ^b   Olsen, Jørn ^a,c   Olsen, Sjurdur Frodi ^d  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d STATENS SERUM INSTITUT   (Denmark)

Author keywords

Cohort studies; Epilepsy; Fatty acids; Omega 3; Pregnancy

Indexed keywords

LONG CHAIN FATTY ACID; OMEGA 3 FATTY ACID;

ADOLESCENT; ADULT; ARTICLE; COHORT ANALYSIS; CONTAMINATED FISH; CONTROLLED STUDY; EPILEPSY; FAT INTAKE; FEMALE; FETUS RISK; FOLLOW UP; FOOD FREQUENCY QUESTIONNAIRE; FOOD INTAKE; GESTATION PERIOD; HUMAN; MALE; MATERNAL NUTRITION; ONSET AGE; PATIENT INFORMATION; PRIORITY JOURNAL; PROGENY; RISK ASSESSMENT; RISK FACTOR;

ADOLESCENT; ADULT; ANIMALS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; EPILEPSY; FATTY ACIDS, OMEGA-3; FEMALE; FISHES; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT, NEWBORN; MALE; POPULATION SURVEILLANCE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REGISTRIES; RISK FACTORS; YOUNG ADULT;

EID: 77957019643     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2010.08.001     Document Type: Article

References (37)

1. Andersen T.F., Madsen M., Jørgensen J., Mellemkjær L., Olsen J.H. The Danish National Hospital Register. A valuable source of data for modern health sciences. Dan. Med. Bull. 1999, 46:263-268.
2. Bakker E.C., Ghys A.J., Kester A.D., Vles J.S., Dubas J.S., Blanco C.E., Hornstra G. Long-chain polyunsaturated fatty acids at birth and cognitive function at 7 y of age. Eur. J. Clin. Nutr. 2003, 57:89-95.
3. Bech B.H., Nohr E.A., Vaeth M., Henriksen T.B., Olsen J. Coffee and fetal death: a cohort study with prospective data. Am. J. Epidemiol. 2005, 162:983-990.
4. Bromfield E., Dworetzky B., Hurwitz S., Eluri Z., Lane L., Replansky S., Mostofsky D. A randomized trial of polyunsaturated fatty acids for refractory epilepsy. Epilepsy Behav. 2008, 12:187-190.
5. Christensen J., Vestergaard M., Olsen J., Sidenius P. Validation of epilepsy diagnoses in the Danish National Hospital Register. Epilepsy Res. 2007, 75:162-170.
6. Christensen J., Vestergaard M., Pedersen M.G., Pedersen C.B., Olsen J., Sidenius P. Incidence and prevalence of epilepsy in Denmark. Epilepsy Res. 2007, 76:60-65.
7. Debes F., Budtz-Jorgensen E., Weihe P., White R.F., Grandjean P. Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years. Neurotoxicol. Teratol. 2006, 28:536-547.
8. DeGiorgio C.M., Miller P., Meymandi S., Gornbein J.A. n-3 Fatty acids (fish oil) for epilepsy, cardiac risk factors, and risk of SUDEP: clues from a pilot, double-blind, exploratory study. Epilepsy Behav. 2008, 13:681-684.
9. Fisher R.S., van Emde Boas W., Blume W., Elger C., Genton P., Engel J. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005, 46:470-472.
10. Grandjean P., Weihe P., Jorgensen P.J., Clarkson T., Cernichiari E., Videro T. Impact of maternal seafood diet on fetal exposure to mercury, selenium, and lead. Arch. Environ. Health 1992, 47:185-195.
11. Grandjean P., Weihe P., White R.F., Debes F. Cognitive performance of children prenatally exposed to " safe" levels of methylmercury. Environ Res. 1998, 77:165-172.
12. Grandjean P., Weihe P., White R.F., Debes F., Araki S., Yokoyama K., Murata K., Sorensen N., Dahl R., Jorgensen P.J. Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol. Teratol. 1997, 19:417-428.
13. Hibbeln J.R., Davis J.M., Steer C., Emmett P., Rogers I., Williams C., Golding J. Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. Lancet 2007, 369:578-585.
14. Innis S.M. Essential fatty acids in growth and development. Prog. Lipid Res. 1991, 30:39-103.
15. Innis S.M. Dietary (n-3) fatty acids and brain development. J. Nutr. 2007, 137:855-859.
16. Innis S.M., Elias S.L. Intakes of essential n-6 and n-3 polyunsaturated fatty acids among pregnant Canadian women. Am. J. Clin. Nutr. 2003, 77:473-478.
17. Knudsen L.B., Olsen J. The Danish Medical Birth Registry. Dan. Med. Bull. 1998, 45:320-323.
18. Koletzko B., Lien E., Agostoni C., Bohles H., Campoy C., Cetin I., Decsi T., Dudenhausen J.W., Dupont C., Forsyth S., Hoesli I., Holzgreve W., Lapillonne A., Putet G., Secher N.J., Symonds M., Szajewska H., Willatts P., Uauy R. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J. Perinat. Med. 2008, 36:5-14.
19. Lilienfeld A.M., Pasamanick B. Association of maternal and fetal factors with the development of epilepsy. I. Abnormalities in the prenatal and paranatal periods. J. Am. Med. Assoc. 1954, 155:719-724.
20. Mikkelsen T.B., Osler M., Olsen S.F. Validity of protein, retinol, folic acid and n-3 fatty acid intakes estimated from the food-frequency questionnaire used in the Danish National Birth Cohort. Public Health Nutr. 2006, 9:771-778.
21. Myers G.J., Davidson P.W. Does methylmercury have a role in causing developmental disabilities in children?. Environ. Health Perspect. 2000, 108(Suppl. 3):413-420.
22. Olsen J., Melbye M., Olsen S.F., Sørensen T.I.A., Aaby P., Andersen A.M.N., Taxbøl D., Hansen K.D., Juhl M., Schow T.B., Sørensen H.T., Andresen J., Mortensen E.L., Olesen A.W., Søndergaard C. The Danish National Birth Cohort-its background, structure and aim. Scand. J. Public Health 2001, 29:300-307.
23. Olsen S.F., Mikkelsen T.B., Knudsen V.K., Orozova-Bekkevold I., Halldorsson T.I., Strom M., Osterdal M.L. Data collected on maternal dietary exposures in the Danish National Birth Cohort. Paediatr. Perinat. Epidemiol. 2007, 21:76-86.
24. Rice D., Barone S. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ. Health Perspect. 2000, 108(Suppl. 3):511-533.
25. Schlanger S., Shinitzky M., Yam D. Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients. Epilepsia 2002, 43:103-104.
26. Skerfving S. Methylmercury exposure, mercury levels in blood and hair, and health status in Swedes consuming contaminated fish. Toxicology 1974, 2:3-23.
27. Sun Y., Vestergaard M., Christensen J., Nahmias A.J., Olsen J. Prenatal exposure to maternal infections and epilepsy in childhood: a population-based cohort study. Pediatrics 2008, 121:E1100-E1107.
28. Sun Y., Vestergaard M., Pedersen C.B., Christensen J., Basso O., Olsen J. Gestational age, birth weight, intrauterine growth, and the risk of epilepsy. Am. J. Epidemiol. 2008, 167:262-270.
29. Taha A.Y., Baghiu B.M., Lui R., Nylen K., Ma D.W., Burnham W.M. Lack of benefit of linoleic and alpha-linolenic polyunsaturated fatty acids on seizure latency, duration, severity or incidence in rats. Epilepsy Res. 2006, 71:40-46.
30. Taha A.Y., Filo E., Ma D.W., McIntyre B.W. Dose-dependent anticonvulsant effects of linoleic and alpha-linolenic polyunsaturated fatty acids on pentylenetetrazol induced seizures in rats. Epilepsia 2009, 50:72-82.
31. Taha A.Y., Huot P.S., Reza-Lopez S., Prayitno N.R., Kang J.X., Burnham W.M., Ma D.W. Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids. J. Neurochem. 2008, 105:380-388.
32. Taha A.Y., Jeffrey M.A., Taha N.M., Bala S., Burnham W.M. Acute administration of docosahexaenoic acid increases resistance to pentylenetetrazol-induced seizures in rats. Epilepsy Behav. 2010, 17:336-343.
33. Whitehead E., Dodds L., Joseph K.S., Gordon K.E., Wood E., Allen A.C., Camfield P., Dooley J.M. Relation of pregnancy and neonatal factors to subsequent development of childhood epilepsy: a population-based cohort study. Pediatrics 2006, 117:1298-1306.
34. Willett W.C., Howe G.R., Kushi L.H. Adjustment for total energy intake in epidemiologic studies. Am. J. Clin. Nutr. 1997, 65:1220S-1228S.
35. Willis S., Samala R., Rosenberger T.A., Borges K. Eicosapentaenoic and docosahexaenoic acids are not anticonvulsant or neuroprotective in acute mouse seizure models. Epilepsia 2009, 50:138-142.
36. Yehuda S., Carasso R.L., Mostofsky D.I. Essential fatty acid preparation (SR-3) raises the seizure threshold in rats. Eur. J. Pharmacol. 1994, 254:193-198.
37. Yuen A.W., Sander J.W., Fluegel D., Patsalos P.N., Bell G.S., Johnson T., Koepp M.J. Omega-3 fatty acid supplementation in patients with chronic epilepsy: a randomized trial. Epilepsy Behav. 2005, 7:253-258.