Liquid chromatography-tandem mass spectrometry for the simultaneous quantitation of artemether and lumefantrine in human plasma: Application for a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis

Volumn 54, Issue 1, 2011, Pages 114-120

  César, Isabela Costa ^a   de Aquino Ribeiro, José Antônio ^a   de Souza Teixeira, Leonardo ^b   Bellorio, Karini Bruno ^b   de Abreu, Fernanda Crunivel ^b   Moreira, Josianny Mesquita ^b   Chellini, Paula Rocha ^a   Pianetti, Gerson Antônio ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b Instituto de Ciencias Farmaceuticas   (Brazil)

Author keywords

Artemether; HPLC ESI MS MS; Lumefantrine; Pharmacokinetics; Plasma

Indexed keywords

ACETIC ACID; AMMONIUM ACETATE; ARTEMETHER; ARTEMETHER PLUS BENFLUMETOL; ARTESUNATE; BENFLUMETOL; FORMIC ACID; METHANOL;

ANALYTICAL EQUIPMENT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION STUDY;

ACETATES; ACETIC ACID; ANTIMALARIALS; ARTEMISININS; CALIBRATION; CHROMATOGRAPHY, LIQUID; ETHANOLAMINES; FLUORENES; FORMIC ACIDS; HUMANS; METHANOL; MODELS, CHEMICAL; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 77957016229     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.07.027     Document Type: Article

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