Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 34, 2010, Pages 15016-15021

  Dunse, K M ^a,b   Kaas, Q ^c   Guarino, R F ^a   Barton, P A ^d   Craik, D J ^c   Anderson, M A ^a,b  

^a LA TROBE UNIVERSITY   (Australia)

^b Hexima Limited   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Chymotrypsin mutants; Inhibitor resistant proteinase; Lepidoptera

Indexed keywords

AMINO ACID; ARGININE; CHYMOTRYPSIN; COMPLEMENTARY DNA; NICOTIANA ALATA PROTEINASE INHIBITOR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; INSECT PROTEIN; PIN2 PROTEIN, SOLANUM AMERICANUM; RECOMBINANT PROTEIN; VEGETABLE PROTEIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; CROP PROTECTION; ENZYME ACTIVATION; ENZYME PURIFICATION; HELICOVERPA; INSECT; INSECT RESISTANCE; LARVA; MOLECULAR MODEL; MUTANT; NICOTIANA ALATA; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOTH; PATHOGENICITY; POTATO; SEQUENCE HOMOLOGY;

HELICOVERPA; HEXAPODA; LEPIDOPTERA; NICOTIANA ALATA; SOLANUM TUBEROSUM;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; CHYMOTRYPSIN; INSECT PROTEINS; LARVA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTHS; PLANT PROTEINS; PROTEASE INHIBITORS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SOLANUM TUBEROSUM;

EID: 77957006259     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009327107     Document Type: Article

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