Grb10 interacts with Bim L and inhibits apoptosis

Molecular Biology Reports

Volumn 37, Issue 7, 2010, Pages 3547-3552

  Hu, Zhi Qian ^a,b   Zhang, Jia Yi ^a   Ji, Chao Neng ^a   Xie, Yi ^a   Chen, Jin Zhong ^a   Mao, Yu Min ^a  

^a FUDAN UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bim; Grb10; Interaction; Phosphorylation sites

Indexed keywords

BIM PROTEIN; DYNEIN ADENOSINE TRIPHOSPHATASE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10;

APOPTOSIS; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; GRB10 ADAPTOR PROTEIN; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SPACE; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SUBCELLULAR FRACTIONS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 77956972424     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0002-9     Document Type: Article

References (18)

1. MD Jacobsen M Weil MC Raff 1997 Programmed cell death in animal development Cell 88 347 354 10.1016/S0092-8674(00)81873-5
2. JM Adams S Cory 1998 The Bcl-2 protein family: arbiters of cell survival Science 281 1322 1326 1:CAS:528:DyaK1cXlvVegsb8%3D 10.1126/science.281.5381.1322 9735050
3. S Cory DC Huang JM Adams 2003 The Bcl-2 family: roles in cell survival and oncogenesis Oncogene 22 8590 8607 1:CAS:528:DC%2BD3sXptFOmtb0%3D 10.1038/sj.onc.1207102 14634621
4. L O'Connor A Strasser LA O'Reilly GM Hausmann J Adams S Cory DC Huang 1998 Bim: a novel member of the Bcl-2 family that promotes apoptosis EMBO J 17 384 395 10.1093/emboj/17.2.384 9430630
5. U Mami T Miyashita Y Shikama K Tadokoro M Yamada 2001 Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family FEBS Lett 509 135 141 10.1016/S0014-5793(01)03145-3
6. JZ Chen CN Ji SH Gu JX Li EP Zhao Y Huang L Huang K Ying Y Xie YM Mao 2004 Over-expression of Bim α3, a novel isoform of human Bim, result in cell apoptosis Int J Biochem Cell Biol 36 1554 1561 1:CAS:528: DC%2BD2cXktVelsLc%3D 15147734
7. H Puthalakath DC Huang LA O' Reilly SM King A Strasser 1999 The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex Mol Cell 3 287 296 1:CAS:528:DyaK1MXit1Oms7k%3D 10.1016/S1097-2765(00)80456-6 10198631
8. CA Harris EM Johnson Jr 2001 BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons J Biol Chem 276 37754 37760 1:CAS:528:DC%2BD3MXotFOrsbc%3D 11495903
9. K Lei RJ Davis 2003 JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis PNAS 100 2432 2437 1:CAS:528:DC%2BD3sXitVaisr8%3D 10.1073/pnas.0438011100 12591950
10. GV Putcha S Le S Frank CG Besirli K Clark B Chu S Alix RJ Youle A LaMarche AC Maroney EM Johnson Jr 2003 JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis Neuron 38 899 914 1:CAS:528: DC%2BD3sXltFanu7k%3D 10.1016/S0896-6273(03)00355-6 12818176
11. M Adachi X Zhao K Imai 2005 Nomenclutrue of dynein light chain-linked BH3-only protein Bim isoforms Cell Death Differ 12 192 193 1:CAS:528: DC%2BD2MXivFKgsA%3D%3D 10.1038/sj.cdd.4401529 15592437
12. JD Pinon V Labi A Egle A Villunger 2009 Bim and Bmf tissue homeostasis and malignant disease Oncogene 27 s41 s52 10.1038/onc.2009.42
13. J Wan SL Kang C Tang JH Yan YL Ren J Liu XL Gao A Banerjee LBM Ellis TB Li 2008 Meta- prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection Nucleic Acids Res 36 1 11 10.1093/nar/gkn381
14. Y Xue F Zhou M Zhu K Ahmed G Chen X Yao 2005 GPS: a comprehensive www server for phosphorylation sites prediction Nucleic Acids Res 33 W184 W187 1:CAS:528:DC%2BD2MXlslyrurg%3D 10.1093/nar/gki393 15980451
15. H Riedel 2004 Grb10 exceeding the boundaries of a common signaling adapter Front Biosci 9 603 618 1:CAS:528:DC%2BD2cXhtFCktLY%3D 10.2741/1227 14766395
16. A Morrione 2003 Grb10 adapter protein as regulator of insulin-like growth factor receptor signaling J Cell Physiol 197 307 311 1:CAS:528: DC%2BD3sXoslegtLw%3D 10.1002/jcp.10363 14566960
17. A Morrione P Plant B Valentinis O Staub S Kumar D Rotin R Baserga 1999 mGrb10 interacts with Nedd4 J Biol Chem 274 24094 24099 1:CAS:528: DyaK1MXlsVOntLY%3D 10.1074/jbc.274.34.24094 10446181
18. R Ley KE Ewings K Hadfield SJ Cook 2005 Regulatory phosphorylation of Bim: sorting out the ERK from the JNK Cell Death Differ 12 1008 1414 1:CAS:528:DC%2BD2MXmtVylsr4%3D 10.1038/sj.cdd.4401688 15947788