메뉴 건너뛰기




Volumn 37, Issue 7, 2010, Pages 3407-3412

Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways

Author keywords

Apoptosis; Bcl 2; Caspase; Delisheng; DR5; HepG2

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; DEATH RECEPTOR; DELISHENG; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; UNCLASSIFIED DRUG;

EID: 77956951234     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9930-7     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 0034090264 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • 1:STN:280:DC%2BD3c7ptFWmsw%3D%3D 10.1016/S0168-8278(00)80428-6 10728807
    • K Okuda 2000 Hepatocellular carcinoma J Hepatol 32 225 237 1:STN:280:DC%2BD3c7ptFWmsw%3D%3D 10.1016/S0168-8278(00)80428-6 10728807
    • (2000) J Hepatol , vol.32 , pp. 225-237
    • Okuda, K.1
  • 2
    • 34247110389 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma (HCC): An Update
    • DOI 10.1053/j.seminoncol.2007.01.007, PII S0093775407000243
    • P Rougier E Mitry JC Barbare J Taieb 2007 Hepatocellular carcinoma (HCC): an update Semin Oncol 34 S12 S20 1:CAS:528:DC%2BD2sXmtV2ku7c%3D 10.1053/j.seminoncol.2007.01.007 17449346 (Pubitemid 46590363)
    • (2007) Seminars in Oncology , vol.34 , Issue.SUPPL. 1
    • Rougier, P.1    Mitry, E.2    Barbare, J.-C.3    Taieb, J.4
  • 3
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • JM Llovet A Burroughs J Bruix 2003 Hepatocellular carcinoma Lancet 362 1907 1917 10.1016/S0140-6736(03)14964-1 14667750 (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 4
    • 1242307263 scopus 로고    scopus 로고
    • The Barcelona approach: Diagnosis, staging, and treatment of hepatocellular carcinoma
    • 10.1002/lt.20034
    • JM Llovet J Fuster J Bruix 2004 The Barcelona approach: diagnosis, staging, and treatment of hepatocellular carcinoma Liver Transplant 10 S115 S120 10.1002/lt.20034
    • (2004) Liver Transplant , vol.10
    • Llovet, J.M.1    Fuster, J.2    Bruix, J.3
  • 5
    • 0036256860 scopus 로고    scopus 로고
    • Induction of differentiation in human hepatocarcinoma cells by isoverbascoside
    • DOI 10.1055/s-2002-26759
    • C Rui-Chuan S Jin-Hua O Gao-Liang C Ke-Xia L Jin-Quan X Xiao-Guang 2002 Induction of differentiation in human hepatocarcinoma cells by isoverbascoside Planta Med 68 370 372 10.1055/s-2002-26759 11988868 (Pubitemid 34494055)
    • (2002) Planta Medica , vol.68 , Issue.4 , pp. 370-372
    • Rui-Chuan, C.1    Jin-Hua, S.2    Gao-Liang, O.3    Ke-Xia, C.4    Jin-Quan, L.5    Xiao-Guang, X.6
  • 6
    • 0036304314 scopus 로고    scopus 로고
    • Activity of drugs from traditional chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells
    • DOI 10.1006/bcmd.2002.0492
    • T Efferth M Davey A Olbrich G Rucker E Gebhart R Davey 2002 Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug resistant human CCRF-CEM leukemia cells Blood Cells Mol Dis 28 160 168 10.1006/bcmd.2002.0492 12064912 (Pubitemid 34743750)
    • (2002) Blood Cells, Molecules, and Diseases , vol.28 , Issue.2 , pp. 160-168
    • Efferth, T.1    Davey, M.2    Olbrich, A.3    Rucker, G.4    Gebhart, E.5    Davey, R.6
  • 7
    • 0842286830 scopus 로고    scopus 로고
    • Phase II study of viscum fraxini-2 in patients with advanced hepatocellular carcinoma
    • DOI 10.1038/sj.bjc.6601463
    • M Mabed L El-Helw S Shamaa 2004 Phase II study of viscum fraxini-2 in patients with advanced hepatocellular carcinoma Br J Cancer 90 65 69 1:CAS:528:DC%2BD2cXhtFKnsg%3D%3D 10.1038/sj.bjc.6601463 14710208 (Pubitemid 38174940)
    • (2004) British Journal of Cancer , vol.90 , Issue.1 , pp. 65-69
    • Mabed, M.1    El-Helw, L.2    Shamaa, S.3
  • 8
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • 1:CAS:528:DyaK2sXks1Sjtw%3D%3D 10.1126/science.275.5297.218 8985016
    • M Jang L Cai GO Udeani, et al. 1997 Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 218 220 1:CAS:528:DyaK2sXks1Sjtw%3D%3D 10.1126/science.275.5297.218 8985016
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1    Cai, L.2    Udeani, G.O.3
  • 9
    • 0033673746 scopus 로고    scopus 로고
    • Drug therapy in Chinese traditional medicine
    • 1:STN:280:DC%2BD3c3ms1Gmug%3D%3D 10.1177/00912700022009198 10806595
    • JT Cheng 2000 Drug therapy in Chinese traditional medicine J Clin Pharmacol 40 445 450 1:STN:280:DC%2BD3c3ms1Gmug%3D%3D 10.1177/00912700022009198 10806595
    • (2000) J Clin Pharmacol , vol.40 , pp. 445-450
    • Cheng, J.T.1
  • 11
    • 0030606128 scopus 로고    scopus 로고
    • Bufalin inhibits endothelial cell proliferation and angiogenesis in vitro
    • DOI 10.1016/S0024-3205(96)00602-9, PII S0024320596006029
    • DY Lee M Yasuda T Yammoto, et al. 1997 Bufalin inhibits endothelial cell proliferation and angiogenesis in vitro Life Sci 60 127 134 1:CAS:528: DyaK28XnsFSgsLg%3D 10.1016/S0024-3205(96)00602-9 9000118 (Pubitemid 27022720)
    • (1997) Life Sciences , vol.60 , Issue.2 , pp. 127-134
    • Lee, D.Y.1    Yasuda, M.2    Yamamoto, T.3    Yoshida, T.4    Kuroiwa, Y.5
  • 12
    • 0037304261 scopus 로고    scopus 로고
    • Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells
    • DOI 10.1002/pros.10172
    • JY Yeh WJ Huang SF Kan, et al. 2003 Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells Prostate 54 112 124 1:CAS:528:DC%2BD3sXhtlShtL4%3D 10.1002/pros.10172 12497584 (Pubitemid 36120327)
    • (2003) Prostate , vol.54 , Issue.2 , pp. 112-124
    • Yeh, J.-Y.1    Huang, W.J.2    Kan, S.-F.3    Wang, P.S.4
  • 13
    • 34447321283 scopus 로고    scopus 로고
    • Anti-tumour activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumour model of human hepatocellular carcinoma in nude mice
    • 1:CAS:528:DC%2BD2sXovFWmtLg%3D 17659679
    • Ke-Qi Han G Huang W Gu Y-H Su X-Q Huang C-Q Ling 2007 Anti-tumour activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumour model of human hepatocellular carcinoma in nude mice World J Gastroenterol 13 3374 3379 1:CAS:528:DC%2BD2sXovFWmtLg%3D 17659679
    • (2007) World J Gastroenterol , vol.13 , pp. 3374-3379
    • Ke-Qi, H.1    Huang, G.2    Gu, W.3    Su, Y.-H.4    Huang, X.-Q.5    Ling, C.-Q.6
  • 14
    • 67650435103 scopus 로고    scopus 로고
    • Primary research on Chinese medicine treatment of androgen-independent prostate cancer
    • 10.1007/s11655-009-0168-y
    • Z Shu-wu Z Shi-yi S Ji-chun Q Xiao-wei 2009 Primary research on Chinese medicine treatment of androgen-independent prostate cancer Chin J Integr Med 15 168 169 10.1007/s11655-009-0168-y
    • (2009) Chin J Integr Med , vol.15 , pp. 168-169
    • Shu-Wu, Z.1    Shi-Yi, Z.2    Ji-Chun, S.3    Xiao-Wei, Q.4
  • 15
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • 1:CAS:528:DyaK2sXnsFGls70%3D 10.1016/S0092-8674(00)80434-1 9390557
    • P Li D Nijhawan I Budihardjo SM Srinivasula M Ahmad ES Alnemri X Wang 1997 Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 479 489 1:CAS:528: DyaK2sXnsFGls70%3D 10.1016/S0092-8674(00)80434-1 9390557
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 16
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • DOI 10.1016/S0092-8674(00)81874-7
    • S Nagata 1997 Apoptosis by death factor Cell 88 355 365 1:CAS:528:DyaK2sXhtFahtbg%3D 10.1016/S0092-8674(00)81874-7 9039262 (Pubitemid 27131377)
    • (1997) Cell , vol.88 , Issue.3 , pp. 355-365
    • Nagata, S.1
  • 17
    • 1842611495 scopus 로고    scopus 로고
    • Bcl-2 protein in normal, hyperplastic and neoplastic breast tissues. A metabolite of the putative stem-cell subpopulation of the mammary gland
    • 1:CAS:528:DC%2BD2cXjsVGntrY%3D 15024706
    • S Luna-More B Weil D Bautista E Garrido P Florez C Martinez 2004 Bcl-2 protein in normal, hyperplastic and neoplastic breast tissues. A metabolite of the putative stem-cell subpopulation of the mammary gland Histol Histopathol 19 457 463 1:CAS:528:DC%2BD2cXjsVGntrY%3D 15024706
    • (2004) Histol Histopathol , vol.19 , pp. 457-463
    • Luna-More, S.1    Weil, B.2    Bautista, D.3    Garrido, E.4    Florez, P.5    Martinez, C.6
  • 19
    • 0036716281 scopus 로고    scopus 로고
    • The BCL2 family: Regulators of the cellular life-or-death switch
    • DOI 10.1038/nrc883
    • S Cory JM Adams 2002 The Bcl2 family: regulators of the cellular life-or-death switch Nat Rev Cancer 2 647 656 1:CAS:528:DC%2BD38Xmslamsrw%3D 10.1038/nrc883 12209154 (Pubitemid 37328916)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.9 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 20
    • 3142552523 scopus 로고    scopus 로고
    • Chk1 is haploinsufficient for multiple functions critical to tumor suppression
    • DOI 10.1016/j.ccr.2004.06.015, PII S1535610804001758
    • MH Lam Q Liu SJ Elledge JM Rosen 2004 Chk1 is haploinsufficient for multiple functions critical to tumor suppression Cancer Cell 6 45 59 1:CAS:528:DC%2BD2cXmtlKnt7g%3D 10.1016/j.ccr.2004.06.015 15261141 (Pubitemid 38903161)
    • (2004) Cancer Cell , vol.6 , Issue.1 , pp. 45-59
    • Lam, M.H.1    Liu, Q.2    Elledge, S.J.3    Rosen, J.M.4
  • 21
    • 2442460088 scopus 로고    scopus 로고
    • Role of mitochondrial membrane permeabilization in apoptosis and cancer
    • DOI 10.1038/sj.onc.1207534
    • J Henry-Mowatt C Dive JC Martinou D James 2004 Role of mitochondrial membrane permeabilization in apoptosis and cancer Oncogene 23 2850 2860 1:CAS:528:DC%2BD2cXivFKmsb4%3D 10.1038/sj.onc.1207534 15077148 (Pubitemid 38638847)
    • (2004) Oncogene , vol.23 , pp. 2850-2860
    • Henry-Mowatt, J.1    Dive, C.2    Martinou, J.-C.3    James, D.4
  • 22
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • DOI 10.1016/0092-8674(93)90509-O
    • ZN Oltvai CL Milliman SJ Korsmeyer 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 609 619 1:CAS:528:DyaK3sXms1eqtbs%3D 10.1016/0092-8674(93)90509-O 8358790 (Pubitemid 23259742)
    • (1993) Cell , vol.74 , Issue.4 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 24
    • 33745755472 scopus 로고    scopus 로고
    • Bcl-2 changes conformation to inhibit Bax oligomerization
    • DOI 10.1038/sj.emboj.7601126, PII 7601126
    • PJ Dlugosz LP Billen MG Annis, et al. 2006 Bcl-2 changes conformation to inhibit Bax oligomer izat ion EMBO J 25 2287 2296 1:CAS:528:DC%2BD28XltlGlurk%3D 10.1038/sj.emboj.7601126 16642033 (Pubitemid 44012212)
    • (2006) EMBO Journal , vol.25 , Issue.11 , pp. 2287-2296
    • Dlugosz, P.J.1    Billen, L.P.2    Annis, M.G.3    Zhu, W.4    Zhang, Z.5    Lin, J.6    Leber, B.7    Andrews, D.W.8
  • 25
    • 18544370041 scopus 로고    scopus 로고
    • Cisplatin is a DNA-damaging antitumour compound triggering multifactorial biochemical responses in cancer cells: Importance of apoptotic pathways
    • DOI 10.2174/1568011053765967
    • Y Sedletska MJ Giraud-Panis JM Malinge 2005 Cisplatin is a DNA damaging antitumour compound triggering multifactorial biochemical responses in cancer cells: importance of apoptotic pathways Curr Med Chem Anticancer Agents 5 251 265 1:CAS:528:DC%2BD2MXktlSmsrw%3D 10.2174/1568011053765967 15992353 (Pubitemid 40655276)
    • (2005) Current Medicinal Chemistry - Anti-Cancer Agents , vol.5 , Issue.3 , pp. 251-265
    • Sedletska, Y.1    Giraud-Panis, M.-J.2    Malinge, J.-M.3
  • 26
    • 33750003401 scopus 로고    scopus 로고
    • Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90
    • DOI 10.1016/j.leukres.2006.02.014, PII S0145212606000592
    • A Ryningen E Ersvaer AM Oyan, et al. 2006 Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90 Leuk Res 30 1531 1540 1:CAS:528:DC%2BD28XhtFWitLbI 10.1016/j.leukres.2006.02.014 16600371 (Pubitemid 44573475)
    • (2006) Leukemia Research , vol.30 , Issue.12 , pp. 1531-1540
    • Ryningen, A.1    Ersvaer, E.2    Oyan, A.M.3    Kalland, K.-H.4    Vintermyr, O.K.5    Gjertsen, B.T.6    Bruserud, O.7
  • 27
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • DOI 10.1038/nrm1496
    • SJ Riedl Y Shi 2004 Molecular mechanisms of caspase regulation during apoptosis Nat Rev Mol Cell Biol 5 897 907 1:CAS:528:DC%2BD2cXptFemsL0%3D 10.1038/nrm1496 15520809 (Pubitemid 39486541)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.11 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 28
    • 0344389027 scopus 로고    scopus 로고
    • Caspases: The proteases of the apoptotic pathway
    • 10.1038/sj.onc.1202581
    • G Nuneza MA Benedict Y Hu N Inohara 1998 Caspases: the proteases of the apoptotic pathway Oncogene 17 3237 3245 10.1038/sj.onc.1202581
    • (1998) Oncogene , vol.17 , pp. 3237-3245
    • Nuñeza, G.1    Benedict, M.A.2    Hu, Y.3    Inohara, N.4
  • 29
    • 33644812102 scopus 로고    scopus 로고
    • Caspase family proteases and apoptosis
    • DOI 10.1111/j.1745-7270.2005.00108.x
    • T Fan L Han R Cong J Liang 2005 Caspase family proteases and apoptosis Acta Biochim Biophys Sin 37 719 727 1:CAS:528:DC%2BD2MXhtlWnsbbO 10.1111/j.1745-7270.2005.00108.x 16270150 (Pubitemid 44890981)
    • (2005) Acta Biochimica et Biophysica Sinica , vol.37 , Issue.11 , pp. 719-727
    • Fan, T.-J.1    Han, L.-H.2    Cong, R.-S.3    Liang, J.4
  • 30
    • 0011444717 scopus 로고    scopus 로고
    • Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types
    • 1:CAS:528:DC%2BD3cXntF2qtrY%3D 10.1016/S0014-5793(00)02042-1 11024459
    • XD Zhang T Nguyen WD Thomas JE Sanders P Hersey 2000 Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types FEBS Lett 482 193 199 1:CAS:528:DC%2BD3cXntF2qtrY%3D 10.1016/S0014-5793(00)02042-1 11024459
    • (2000) FEBS Lett , vol.482 , pp. 193-199
    • Zhang, X.D.1    Nguyen, T.2    Thomas, W.D.3    Sanders, J.E.4    Hersey, P.5
  • 31
    • 0033710429 scopus 로고    scopus 로고
    • Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
    • 1:CAS:528:DC%2BD3cXovFWgsb0%3D 10.1038/sj.cdd.4400746 11139287
    • M Dejosez U Ramp C Mahotka, et al. 2000 Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan Cell Death Differ 7 1127 1136 1:CAS:528: DC%2BD3cXovFWgsb0%3D 10.1038/sj.cdd.4400746 11139287
    • (2000) Cell Death Differ , vol.7 , pp. 1127-1136
    • Dejosez, M.1    Ramp, U.2    Mahotka, C.3
  • 32
    • 0035216008 scopus 로고    scopus 로고
    • TRAIL/Apo-2L: Mechanisms and clinical applications in cancer
    • DOI 10.1038/sj.neo.7900203
    • RK Srivastava 2001 TRAIL/Apo-2L: mechanisms and clinical applications in cancer Neoplasia 3 535 546 1:CAS:528:DC%2BD38XksFKjtQ%3D%3D 10.1038/sj.neo. 7900203 11774036 (Pubitemid 33151020)
    • (2001) Neoplasia , vol.3 , Issue.6 , pp. 535-546
    • Srivastava, R.K.1
  • 33
    • 0030996297 scopus 로고    scopus 로고
    • The receptor for the cytotoxic ligand TRAIL
    • DOI 10.1126/science.276.5309.111
    • G Pan K O'Rourke AM Chinnaiyan, et al. 1997 The receptor for the cytotoxic ligand TRAIL Science 276 111 113 1:CAS:528:DyaK2sXitl2jsL4%3D 10.1126/science.276.5309.111 9082980 (Pubitemid 27161256)
    • (1997) Science , vol.276 , Issue.5309 , pp. 111-113
    • Pan, G.1    O'Rourke, K.2    Chinnaiyan, A.M.3    Gentz, R.4    Ebner, R.5    Ni, J.6    Dixit, V.M.7
  • 34
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • DOI 10.1126/science.277.5327.815
    • G Pan J Ni YF Wei G Yu R Gentz VM Dixit 1997 An antagonist decoy receptor and a death domain-containing receptor for TRAIL Science 277 815 818 1:CAS:528:DyaK2sXlt1eksro%3D 10.1126/science.277.5327.815 9242610 (Pubitemid 27366732)
    • (1997) Science , vol.277 , Issue.5327 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.-F.3    Yu, G.-I.4    Gentz, R.5    Dixit, V.M.6
  • 35
    • 0032910169 scopus 로고    scopus 로고
    • Apoptosis control by death and decoy receptors
    • DOI 10.1016/S0955-0674(99)80034-9
    • A Ashkenazi VM Dixit 1999 Apoptosis control by death and decoy receptors Curr Opin Cell Biol 11 255 260 1:CAS:528:DyaK1MXisFWlsbk%3D 10.1016/S0955- 0674(99)80034-9 10209153 (Pubitemid 29164042)
    • (1999) Current Opinion in Cell Biology , vol.11 , Issue.2 , pp. 255-260
    • Ashkenazi, A.1    Dixit, V.M.2
  • 36
    • 14044278251 scopus 로고    scopus 로고
    • Death receptor signaling
    • DOI 10.1242/jcs.01610
    • I Lavrik A Golks PH Krammer 2005 Death receptor signaling J Cell Sci 118 265 267 1:CAS:528:DC%2BD2MXhslymtbg%3D 10.1242/jcs.01610 15654015 (Pubitemid 40277339)
    • (2005) Journal of Cell Science , vol.118 , Issue.2 , pp. 265-267
    • Lavrik, I.1    Golks, A.2    Krammer, P.H.3
  • 37
    • 0345015844 scopus 로고    scopus 로고
    • Death receptors
    • 1:CAS:528:DC%2BD2cXivFCiu7o%3D 14585074
    • H Wajant 2003 Death receptors Essays Biochem 39 53 71 1:CAS:528:DC%2BD2cXivFCiu7o%3D 14585074
    • (2003) Essays Biochem , vol.39 , pp. 53-71
    • Wajant, H.1
  • 38
    • 0034682695 scopus 로고    scopus 로고
    • Mitochondria - The death signal integrators
    • DOI 10.1126/science.289.5482.1150
    • C Brenner G Kroemer 2000 Apoptosis: mitochondria-the death signal integrators Science 289 1150 1151 1:CAS:528:DC%2BD3cXmt1Wjurg%3D 10.1126/science.289.5482.1150 10970229 (Pubitemid 30650720)
    • (2000) Science , vol.289 , Issue.5482 , pp. 1150-1151
    • Brenner, C.1    Kroemer, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.