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77956934778
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For a strategy to install a difluoromethyl group on the nitrogen atom of a 2-pyridinone see
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The heat of reaction =+436.9 kJ/mol; T adiabatic = +242.6 K
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The heat of reaction =-436.9 kJ/mol; T adiabatic = +242.6 K.
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For an example of zinc acetate improving the conversion of a palladium-catalyzed cyanation see
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77956931889
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For an example of additive effects on cyanide solubility see
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For an example of additive effects on cyanide solubility see
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47
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7044233533
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48
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77956912402
-
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The stability of P-3 relative to that of N-2 and N-4 is unclear because it is a transient polymorph only obtained during the N-1 to N-3 conversion
-
The stability of P-3 relative to that of N-2 and N-4 is unclear because it is a transient polymorph only obtained during the N-1 to N-3 conversion.
-
-
-
-
49
-
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77956901714
-
-
The level of residual zinc was <10 ppm, and the level of residual NMP was <0.02 wt %.
-
The level of residual zinc was <10 ppm, and the level of residual NMP was <0.02 wt %.
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