The conserved CXXC motif of hepatic stimulator substance is essential for its role in mitochondrial protection in H2O2-induced cell apoptosis

FEBS Letters

Volumn 584, Issue 18, 2010, Pages 3929-3935

  Li, Wen ^a   Zhang, Jing ^a   An, Wei ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; CXXC motif; Hepatic stimulator substance; Mitochondria; Sulfhydryl oxidase

Indexed keywords

DISULFIDE; HEPATIC STIMULATOR SUBSTANCE; HYDROGEN PEROXIDE; LIVER PROTECTIVE AGENT; RECOMBINANT PROTEIN; THIOL OXIDASE; UNCLASSIFIED DRUG; PEPTIDE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; DIMERIZATION; DISULFIDE BOND; ENZYME ACTIVITY; ENZYME ASSAY; GENETIC TRANSFECTION; HEPATOMA CELL; MITOCHONDRION; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; WESTERN BLOTTING; CATALYSIS; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; LIVER; LIVER MITOCHONDRION; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; TOXICITY; TUMOR CELL LINE;

AMINO ACID MOTIFS; APOPTOSIS; CATALYSIS; CELL LINE, TUMOR; CONSERVED SEQUENCE; HUMANS; HYDROGEN PEROXIDE; LIVER; MITOCHONDRIA, LIVER; MUTATION; PEPTIDES;

EID: 77956905616     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.08.043     Document Type: Article

References (19)

1. LaBrecque D.R., Pesch L.A. Preparation and partial characterization of hepatic regenerative stimulator substance (SS) from rat liver. J. Physiol. 1975, 248:273-284.
2. Gandhi C.R., Kuddus R., Subbotin V.M., Prelich J., Murase N., Rao A.S., Nalesnik M.A., Watkins S.C., DeLeo A., Trucco M., Starzl T.E. A fresh look at augmenter of liver regeneration in rats. Hepatology 1999, 29:1435-1445.
3. LaBrecque D.R. In vitro stimulation of cell growth by hepatic stimulator substance. Am. J. Physiol. 1982, 242:G289-G295.
4. Yang X.M., Xie L., Xing G.C., Wu Z.Z., He F.C. Partial isolation and identification of hepatic stimulator substance mRNA extracted from human fetal liver. World J. Gastroenterol. 1998, 4:100-102.
5. Lisowsky T., Lee J.E., Polimeno L., Francavilla A., Hofhaus G. Mammalian augmenter of liver regeneration protein is a sulfhydryl oxidase. Dig. Liver Dis. 2001, 33:173-180.
6. Hoober K.L., Joneja B., White H.B., Thorpe C.A. Sulfhydryl oxidase from chicken egg white. J. Biol. Chem. 1996, 271:30510-30516.
7. Wu C.K., Dailey T.A., Dailey H.A., Wang B.C., Rose J.P. The crystal structure of augmenter of liver regeneration: A mammalian FAD-dependent sulfhydryl oxidase. Protein Sci. 2003, 12:1109-1118.
8. Chen X.X., Li Y., Wei K.H., Li L., Liu W.L., Zhu Y.P., Qiu Z.Y., He F.C. The potentiation role of hepatopoietin on activator protein-1 is dependent on its sulfhydryl oxidase activity. J. Biol. Chem. 2003, 278:49022-49030.
9. Polimeno L., Capuano F., Marangi L.C., Margiotta M., Lisowsky T., Lerardi E., Francavilla R., Francavilla A. The augmenter of liver regeneration induces mitochondrial gene expression in rat liver and enhances oxidative phosphorylation capacity of liver mitochondria. Dig. Liver Dis. 2000, 32:510-517.
10. Mesecke N., Terziyska N., Kozany C., Baumann F., Neupert W., Hell K., Herrmann J.M. A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 2005, 121:1059-1069.
11. Rissler M., Wiedemann N., Pfannschmidt S., Gabriel K., Guiard B., Pfanner N., Chacinska A. The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins. J. Mol. Biol. 2005, 353:485-492.
12. Thirunavukkarasu C., Wang L.F., Harvey S.A.K., Watkins S.C., Chaillet J.R., Prelich J., Starzl T.E., Gandhi C.R. Augmenter of liver regeneration: an important intracellular survival factor for hepatocytes. J. Hepatology 2008, 48:578-588.
13. 2-induced cell apoptosis via preservation of mitochondria. Arch. Biochem. Biophys. 2007, 464:48-56.
14. Wu Y., Zhang J., Dong L.Y., Li W., Jia J.D., An W. Hepatic stimulator substance mitigates hepatic cell Injury through suppression of the mitochondrial permeability transition. FEBS J. 2010, 277:1297-1309.
15. Hoober K.L., Sheasley S.L., Gilbert H.F., Thorpe C. Sulfhydryl oxidase from egg white. A facile catalyst for disulfide bond formation in proteins and peptides. J. Biol. Chem. 1999, 274:22147-22150.
16. Lee J.-E., Hofhaus G., Lisowsky T. Erv1p from Saccharomyces cerevisiae is a FAD-linked sulfhydryl oxidase. FEBS Lett. 2000, 477:62-66.
17. Cossarizza A., Franceschi C., Monti D., Salvioli S., Bellesia E., Rivabene R., Biondo L., Rainaldi G., Tinari A., Malorni W. Protective effect of N-acetylcysteine in tumor necrosis factor-α induced apoptosis in U937 cells: the role of mitochondria. Exp. Cell Res. 1995, 220:232-240.
18. Vahsen N., Cande C., Briere J.J., Benit P., Joza N., Larochette N., Mastroberardino P.G., Pequignot M.O., Casares N., Lazar V., Feraud O., Debili N., Wissing S., Engelhardt S., Madeo F., Piacentini M., Penninger J.M., Schagger H., Rustin P., Kroemer G. AIF deficiency compromises oxidative phosphorylation. EMBO J. 2004, 23:4679-4689.
19. Cao Y., Fu Y.L., Yu M., Yue P.B., Ge C.H., Xu W.X., Zhan Y.Q., Li C.Y., Li W., Wang X.H., Wang Z.D., Li Y.H., Yang X.M. Human augmenter of liver regeneration is important for hepatoma cell viability and resistance to radiation-induced oxidative stress. Free Radic. Biol. Med. 2009, 47:1057-1066.