Treating profound hyponatremia: A strategy for controlled correction

American Journal of Kidney Diseases

Volumn 56, Issue 4, 2010, Pages 774-779

  Sterns, Richard H ^a   Hix, John Kevin ^a   Silver, Stephen ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

antidiuretic hormone; desmopressin; hypertonic saline; Hyponatremia

Indexed keywords

DESMOPRESSIN; POTASSIUM; POTASSIUM CHLORIDE; SEDATIVE AGENT; SEROTONIN UPTAKE INHIBITOR; SODIUM; SODIUM CHLORIDE; THIAZIDE DIURETIC AGENT; ARGIPRESSIN[1 DEAMINO];

ADULT; ALCOHOL WITHDRAWAL; ALCOHOLISM; ARTICLE; BLOOD SAMPLING; BRAIN; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; DELIRIUM; DELIRIUM TREMENS; DEMYELINATION; DEPRESSION; DISEASE CONTROL; DIURESIS; HUMAN; HYPERTENSION; HYPONATREMIA; HYPOVOLEMIA; INTENSIVE CARE UNIT; LABORATORY TEST; MALE; NEUROIMAGING; PROFOUND HYPONATREMIA; SEIZURE; SODIUM BLOOD LEVEL; TREATMENT OUTCOME; URINE VOLUME; ALCOHOL-RELATED DISORDERS; BLOOD ANALYSIS; BRAIN DISEASES; CHEMICALLY INDUCED; COMPLICATION; DEMYELINATING DISEASES; FOLLOW UP; METABOLISM; MIDDLE AGED; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX;

ALCOHOL-RELATED DISORDERS; BLOOD CHEMICAL ANALYSIS; BRAIN DISEASES; DEAMINO ARGININE VASOPRESSIN; DEMYELINATING DISEASES; FOLLOW-UP STUDIES; HUMANS; HYPONATREMIA; MALE; MIDDLE AGED; RISK ASSESSMENT; SALINE SOLUTION, HYPERTONIC; SEVERITY OF ILLNESS INDEX; SODIUM; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 77956902830     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2010.04.020     Document Type: Article

References (17)

1. T. Berl, and A. Rastega A patient with severe hyponatremia and hypokalemia: osmotic demyelination following potassium repletion Am J Kidney Dis 55 4 2010 742 748
2. B.E. Tomlinson, A.M. Pierides, and W.G. Bradley Central pontine myelinolysis Two cases with associated electrolyte disturbance Q J Med 45 179 1976 373 386
3. R.H. Sterns, J.E. Riggs, and S.S. Schochet Jr Osmotic demyelination syndrome following correction of hyponatremia N Engl J Med 314 24 1986 1535 1542
4. J.E. Brunner, J.M. Redmond, A.M. Haggar, D.F. Kruger, and S.B. Elias Central pontine myelinolysis and pontine lesions after rapid correction of hyponatremia: a prospective magnetic resonance imaging study Ann Neurol 27 1 1990 61 66
5. B.I. Karp, and R. Laureno Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia Medicine (Baltimore) 72 6 1993 359 373
6. R.H. Sterns, J.D. Cappuccio, S.M. Silver, and E.P. Cohen Neurologic sequelae after treatment of severe hyponatremia: a multicenter perspective J Am Soc Nephrol 4 8 1994 1522 1530
7. B.L. Hart, and R.P. Eaton Images in clinical medicine Osmotic myelinolysis N Engl J Med 333 19 1995 1259
8. S.H. Lin, T. Chau, C.C. Wu, and S.S. Yang Osmotic demyelination syndrome after correction of chronic hyponatremia with normal saline Am J Med Sci 323 5 2002 259 262
9. R.H. Sterns, S.U. Nigwekar, and J.K. Hix The treatment of hyponatremia Semin Nephrol 29 3 2009 282 299
10. H.K. Mohmand, D. Issa, Z. Ahmad, J.D. Cappuccio, R.W. Kouides, and R.H. Sterns Hypertonic saline for hyponatremia: risk of inadvertent overcorrection Clin J Am Soc Nephrol 2 6 2007 1110 1117
11. A. Perianayagam, R.H. Sterns, and S.M. Silver DDAVP is effective in preventing and reversing inadvertent overcorrection of hyponatremia Clin J Am Soc Nephrol 3 2 2008 331 336
12. R.H. Sterns, and S.M. Silver Brain volume regulation in response to hypo-osmolality and its correction Am J Med 119 7 suppl 1 2006 S12 S16
13. R.H. Sterns, and J.K. Hix Overcorrection of hyponatremia is a medical emergency Kidney Int 76 6 2009 587 589
14. A. Soupart, M. Ngassa, and G. Decaux Therapeutic relowering of the serum sodium in a patient after excessive correction of hyponatremia Clin Nephrol 51 6 1999 383 386
15. S. Oya, K. Tsutsumi, K. Ueki, and T. Kirino Reinduction of hyponatremia to treat central pontine myelinolysis Neurology 57 10 2001 1931 1932
16. M. Croxson, J. Lucas, and W. Bagg Diluting delirium N Z Med J 118 1222 2005 U1661
17. H.J. Adrogu, and N.E. Madias Hyponatremia N Engl J Med 342 21 2000 1581 1589