A ceramic-based anticancer drug delivery system to treat breast cancer

Journal of Materials Science: Materials in Medicine

Volumn 21, Issue 9, 2010, Pages 2701-2710

  El Ghannam, Ahmed ^a   Ricci, Krista ^b   Malkawi, Ahmed ^c   Jahed, Kiarash ^d   Vedantham, Kumar ^a   Wyan, Heather ^b   Allen, Lauren D ^b   Dréau, Didier ^b  

^a University of North Carolina at Charlotte   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-FLUOROURACIL (5-FU); ANTI-CANCER DRUG DELIVERY; BLOOD ANALYSIS; BREAST CANCER; BURST RELEASE; CYTOTOXIC; DELIVERY SYSTEMS; DRUG DELIVERY SYSTEM; IN-VITRO; MAMMARY TUMORS; MURINE MODEL; POROUS SILICA; RELEASE KINETICS; SIDE EFFECT; SOLID TUMORS; SUSTAINED RELEASE; THERAPEUTIC DOSE; THERAPEUTIC EFFICACY; TOXIC EFFECT; TUMOR GROWTH;

ANIMALS; CALCIUM; CALCIUM PHOSPHATE; DISKS (STRUCTURAL COMPONENTS); DRUG DELIVERY; NANOCOMPOSITES; SILICA; TUMORS;

DRUG DOSAGE;

CALCIUM PHOSPHATE; FLUOROURACIL;

ARTICLE; BREAST CANCER; CERAMICS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MECHANISM; DRUG RELEASE; FOURIER TRANSFORM MASS SPECTROMETRY; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; TUMOR CELL;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CERAMICS; FEMALE; HUMANS;

ANIMALIA; MURINAE;

EID: 77956902265     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-010-4121-6     Document Type: Article

References (52)

1. EP Goldberg AR Hadba BA Almond JS Marotta 2002 Intratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic preoperative drug delivery J Pharm Pharmacol 54 159 180 1:CAS:528:DC%2BD38XitVSqu7w%3D 10.1211/0022357021778268 11848280 (Pubitemid 34150053)
2. MR Dreher W Liu CR Michelich MW Dewhirst F Yuan A Chilkoti 2006 Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers J Natl Cancer Inst 98 335 344 1:CAS:528:DC%2BD28XitVyjsrg%3D 10.1093/jnci/djj070 16507830 (Pubitemid 43338213)
3. G Ragupathi M Meyers S Adluri L Howard C Musselli PO Livingston 2000 Induction of antibodies against GD3 ganglioside in melanoma patients by vaccination with GD3-lactone-KLH conjugate plus immunological adjuvant QS-21 Int J Cancer 85 659 666 1:CAS:528:DC%2BD3cXht1aqsL4%3D 10.1002/(SICI)1097- 0215(20000301)85:5<659::AID-IJC11>3.0.CO;2-5 10699946 (Pubitemid 30080479)
4. YC He JW Chen J Cao DY Pan JG Qiao 2003 Toxicities and therapeutic effect of 5-fluorouracil controlled release implant on tumor-bearing rats World J Gastroenterol 9 1795 1798 1:CAS:528:DC%2BD3sXnsVyqs70%3D 12918123
5. F Curnis A Sacchi A Corti 2002 Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration J Clin Invest 110 475 482 1:CAS:528:DC%2BD38XmsVSiurk%3D 12189241
6. HP Schlemmer M Becker P Bachert A Dietz V Rudat B Vanselow P Wollensack I Zuna MV Knopp H Weidauer M Wannenmacher G van Kaick 1999 Alterations of intratumoral pharmacokinetics of 5-fluorouracil in head and neck carcinoma during simultaneous radiochemotherapy Cancer Res 59 2363 2369 1:CAS:528:DyaK1MXjsVygtLc%3D 10344745
7. P Wu DW Grainger 2006 Drug/device combinations for local drug therapies and infection prophylaxis Biomaterials 27 2450 2467 1:CAS:528: DC%2BD2MXhtlertb%2FL 10.1016/j.biomaterials.2005.11.031 16337266 (Pubitemid 41821824)
8. A El-Ghannam 2005 Bone reconstruction: from bioceramics to tissue engineering Expert Rev Med Devices 2 87 101 10.1586/17434440.2.1.87 16293032 (Pubitemid 40124904)
9. J Akbuga N Bergisadi 1996 5-Fluorouracil-loaded chitosan microspheres: preparation and release characteristics J Microencapsul 13 161 168 1:CAS:528:DyaK28XhvFGls7k%3D 10.3109/02652049609052904 8999121 (Pubitemid 26121877)
10. K Ciftci AA Hincal HS Kas TM Ercan A Sungur O Guven S Ruacan 1997 Solid tumor chemotherapy and in vivo distribution of fluorouracil following administration in poly(l-lactic acid) microspheres Pharm Dev Technol 2 151 160 1:CAS:528:DyaK2sXjvVygsbs%3D 10.3109/10837459709022620 9552441
11. AR Tzafriri EI Lerner M Flashner-Barak M Hinchcliffe E Ratner H Parnas 2005 Mathematical modeling and optimization of drug delivery from intratumorally injected microspheres Clin Cancer Res 11 826 834 1:CAS:528:DC%2BD2MXislWgu70%3D 15701873
12. N Nishiyama S Okazaki H Cabral M Miyamoto Y Kato Y Sugiyama K Nishio Y Matsumura K Kataoka 2003 Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice Cancer Res 63 8977 8983 1:CAS:528: DC%2BD3sXhtVSqtbbN 14695216
13. JL Au SH Jang J Zheng CT Chen S Song L Hu MG Wientjes 2001 Determinants of drug delivery and transport to solid tumors J Control Release 74 31 46 1:CAS:528:DC%2BD3MXlslansr8%3D 10.1016/S0168-3659(01)00308-X 11489481 (Pubitemid 32727607)
14. AB Dhanikula R Panchagnula 1999 Localized paclitaxel delivery Int J Pharm 183 85 100 1:CAS:528:DyaK1MXjsFKlsb8%3D 10.1016/S0378-5173(99)00087-3 10361159 (Pubitemid 29257954)
15. J Huwyler J Drewe S Krahenbuhl 2008 Tumor targeting using liposomal antineoplastic drugs Int J Nanomed 3 21 29 1:CAS:528:DC%2BD1cXlsV2qtLw%3D 10.2147/IJN.S1253
16. G Fontana L Maniscalco D Schillaci G Cavallaro G Giammona 2005 Solid lipid nanoparticles containing tamoxifen characterization and in vitro antitumoral activity Drug Deliv 12 385 392 1:CAS:528:DC%2BD2MXhtFyitbfP 10.1080/10717540590968855 16253954 (Pubitemid 41572113)
17. S Hampel D Kunze D Haase K Kramer M Rauschenbach M Ritschel A Leonhardt J Thomas S Oswald V Hoffmann B Buchner 2008 Carbon nanotubes filled with a chemotherapeutic agent: a nanocarrier mediates inhibition of tumor cell growth Nanomedicine 3 175 182 1:CAS:528:DC%2BD1cXktFyjtL8%3D 10.2217/17435889.3.2.175 18373424 (Pubitemid 351611854)
18. C Zhang G Qu Y Sun X Wu Z Yao Q Guo Q Ding S Yuan Z Shen Q Ping H Zhou 2008 Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel Biomaterials 29 1233 1241 1:CAS:528:DC%2BD1cXnvVCiug%3D%3D 10.1016/j.biomaterials.2007.11.029 18093646
19. P Lim Soo J Cho J Grant E Ho M Piquette-Miller C Allen 2008 Drug release mechanism of paclitaxel from a chitosan-lipid implant system: effect of swelling, degradation and morphology Eur J Pharm Biopharm 69 149 157 1:CAS:528:DC%2BD1cXktlGlt7c%3D 10.1016/j.ejpb.2007.11.003 18164931
20. H Benghuzzi B England 2001 Biocompatibility of steroid-HA delivery system using adult castrated rams as a model Biomed Sci Instrum 37 275 280 1:CAS:528:DC%2BD3MXjvVKku74%3D 11347402
21. M Itokazu T Sugiyama T Ohno E Wada Y Katagiri 1998 Development of porous apatite ceramic for local delivery of chemotherapeutic agents J Biomed Mater Res 39 536 538 1:CAS:528:DyaK1cXptV2rsQ%3D%3D 10.1002/(SICI)1097-4636(19980315)39: 4<536::AID-JBM5>3.0.CO;2-K 9492212 (Pubitemid 28079714)
22. DT Yapp DK Lloyd J Zhu SM Lehnert 1997 Tumor treatment by sustained intratumoral release of cisplatin: effects of drug alone and combined with radiation Int J Radiat Oncol Biol Phys 39 497 504 1:CAS:528:DyaK2sXmsVClu7w%3D 9308956
23. DJ Netz P Sepulveda VC Pandolfelli AC Spadaro JB Alencastre MV Bentley JM Marchetti 2001 Potential use of gelcasting hydroxyapatite porous ceramic as an implantable drug delivery system Int J Pharm 213 117 125 1:CAS:528: DC%2BD3MXmvFKqtw%3D%3D 10.1016/S0378-5173(00)00659-1 11165099 (Pubitemid 32119467)
24. W Zafirau D Parker W Billotte PK Bajpai 1996 Development of a ceramic device for the continuous local delivery of steroids Biomed Sci Instrum 32 63 70 1:STN:280:DyaK283isVCmsw%3D%3D 8672691
25. BD Shenoy N Udupa R Kamath PU Devi 1999 Evaluation of anti-tumor efficacy of injectable Centchroman in mice bearing Ehrlich ascites carcinoma Indian J Physiol Pharmacol 43 259 262 1:CAS:528:DyaK1MXjvVKns7w%3D 10365323
26. JM Renoir B Stella T Ameller E Connault P Opolon V Marsaud 2006 Improved anti-tumoral capacity of mixed and pure anti-oestrogens in breast cancer cell xenografts after their administration by entrapment in colloidal nanosystems J Steroid Biochem Mol Biol 102 114 127 1:CAS:528:DC%2BD28Xht1Cmt7bP 10.1016/j.jsbmb.2006.09.001 17056251 (Pubitemid 44781183)
27. G Gupta A El-Ghannam S Kirakodu M Khraisheh H Zbib 2007 Enhancement of osteoblast gene expression by mechanically compatible porous Si-rich nanocomposite J Biomed Mater Res B Appl Biomater 81 387 396 17034000 (Pubitemid 46685105)
28. G Gupta S Kirakodu A El-Ghannam 2007 Dissolution kinetics of a Si-rich nanocomposite and its effect on osteoblast gene expression J Biomed Mater Res A 80 486 496 17019725 (Pubitemid 46122683)
29. A El-Ghannam CQ Ning J Mehta 2004 Cyclosilicate nanocomposite: a novel resorbable bioactive tissue engineering scaffold for BMP and bone-marrow cell delivery J Biomed Mater Res A 71 377 390 1:STN:280:DC%2BD2crltFSisQ%3D%3D 10.1002/jbm.a.30128 15470721 (Pubitemid 39488510)
30. AR El-Ghannam 2004 Advanced bioceramic composite for bone tissue engineering: design principles and structure-bioactivity relationship J Biomed Mater Res A 69 490 501 10.1002/jbm.a.30022 15127396
31. CQ Ning J Mehta A El-Ghannam 2005 Effects of silica on the bioactivity of calcium phosphate composites in vitro J Mater Sci Mater Med 16 355 360 1:CAS:528:DC%2BD2MXivVSjsbw%3D 10.1007/s10856-005-0635-8 15803281 (Pubitemid 40575658)
32. Y Liang MA Eid F El Etreby RW Lewis MV Kumar 2002 Mifepristone-induced secretion of transforming growth factor beta1-induced apoptosis in prostate cancer cells Int J Oncol 21 1259 1267 1:CAS:528:DC%2BD38XpsVygtbY%3D 12429976
33. A El-Ghannam CQ Ning 2006 Effect of bioactive ceramic dissolution on the mechanism of bone mineralization and guided tissue growth in vitro J Biomed Mater Res A 76 386 397 1:STN:280:DC%2BD2MnovV2jsg%3D%3D 16270343
34. A El-Ghannam K Ahmed M Omran 2005 Nanoporous delivery system to treat osteomyelitis and regenerate bone: gentamicin release kinetics and bactericidal effect J Biomed Mater Res B Appl Biomater 73 277 284 15674827
35. D Dréau A Karaa C Culberson H Wyan IH McKillop MG Clemens 2006 Bosentan inhibits tumor vascularization and bone metastasis in an immunocompetent skin-fold chamber model of breast carcinoma cell metastasis Clin Exp Metastasis 23 41 53 10.1007/s10585-006-9016-z 16826430 (Pubitemid 44576778)
36. MM Jensen JT Jorgensen T Binderup A Kjaer 2008 Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper BMC Med Imaging 8 16 10.1186/1471-2342-8-16 18925932
37. SH Jang MG Wientjes D Lu JL Au 2003 Drug delivery and transport to solid tumors Pharm Res 20 1337 1350 1:CAS:528:DC%2BD3sXnt1KitLc%3D 10.1023/A:1025785505977 14567626 (Pubitemid 37164040)
38. RE Durand 2001 Intermittent blood flow in solid tumours-an under-appreciated source of 'drug resistance' Cancer Metastasis Rev 20 57 61 1:CAS:528:DC%2BD38XhsVWlurw%3D 10.1023/A:1013181107707 11831648 (Pubitemid 34074679)
39. AW el-Kareh TW Secomb 1997 Theoretical models for drug delivery to solid tumors Crit Rev Biomed Eng 25 503 571 1:STN:280:DyaK1czos1ehug%3D%3D 9719859
40. MR Owen HM Byrne CE Lewis 2004 Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites J Theor Biol 226 377 391 1:CAS:528:DC%2BD2cXptFSltQ%3D%3D 10.1016/j.jtbi.2003.09.004 2069621 14759644 (Pubitemid 38169378)
41. AI Minchinton IF Tannock 2006 Drug penetration in solid tumours Nat Rev Cancer 6 583 592 1:CAS:528:DC%2BD28XntFGlu7w%3D 10.1038/nrc1893 16862189 (Pubitemid 44140857)
42. Y Yang JS Jiang B Du ZF Gan M Qian P Zhang 2009 Preparation and properties of a novel drug delivery system with both magnetic and biomolecular targeting J Mater Sci Mater Med 20 301 307 1:CAS:528:DC%2BD1MXlvFGktg%3D%3D 10.1007/s10856-008-3577-0 18791664
43. A El-Ghannam L Cunningham Jr D Pienkowski A Hart 2007 Bone engineering of the rabbit ulna J Oral Maxillofac Surg 65 1495 1502 10.1016/j.joms.2006.10.031 17656274 (Pubitemid 47081282)
44. PV Phan M Grzanna J Chu A Polotsky A el-Ghannam D Van Heerden DS Hungerford CG Frondoza 2003 The effect of silica-containing calcium-phosphate particles on human osteoblasts in vitro J Biomed Mater Res A 67 1001 1008 10.1002/jbm.a.10162 14613250
45. El-Ghannam A, Hart A, Cunningham L, White D (2009) Evaluation of SCPC toxicity on liver, spleen, heart, kidney and lungs of rabbits after implantation in a segmental bone defect. J Biomed Mater Res A (in press)
46. El-Ghannam A, Dreau D (2008) SCPC-5-FU a novel nanocomposite drug delivery system for cancer treatment in "8th world biomaterials congress", Amsterdam, The Netherlands
47. E Raymond C Buquet-Fagot S Djelloul J Mester E Cvitkovic P Allain C Louvet C Gespach 1997 Antitumor activity of oxaliplatin in combination with 5-fluorouracil and the thymidylate synthase inhibitor AG337 in human colon, breast and ovarian cancers Anticancer Drugs 8 876 885 1:CAS:528: DyaK2sXnslehsb8%3D 10.1097/00001813-199710000-00009 9402315 (Pubitemid 27487802)
48. T Hiraga K Hata F Ikeda J Kitagaki K Fujimoto-Ouchi Y Tanaka T Yoneda 2005 Preferential inhibition of bone metastases by 5′-deoxy-5- fluorouridine capecitabine in the 4T1/luc mouse breast cancer model Oncol Rep 14 695 699 1:CAS:528:DC%2BD2MXpvFGjs7g%3D 16077977
49. JH Kim YS Kim S Kim JH Park K Kim K Choi H Chung SY Jeong RW Park IS Kim IC Kwon 2006 Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel J Control Release 111 228 234 1:CAS:528:DC%2BD28XhslKjt7g%3D 10.1016/j.jconrel.2005.12.013 16458988 (Pubitemid 43290012)
50. AM Al-Ghananeem AH Malkawi YM Muammer JM Balko EP Black W Mourad E Romond 2009 Intratumoral delivery of Paclitaxel in solid tumor from biodegradable hyaluronan nanoparticle formulations AAPS PharmSciTech 10 410 417 1:CAS:528:DC%2BC3cXovFantr8%3D 10.1208/s12249-009-9222-5 19381833
51. H Lee K Lee TG Park 2008 Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity Bioconj Chem 19 1319 1325 1:CAS:528:DC%2BD1cXlvFakt7c%3D 10.1021/bc8000485 (Pubitemid 351874956)
52. M He Z Zhao L Yin C Tang C Yin 2009 Hyaluronic acid coated poly(butyl cyanoacrylate) nanoparticles as anticancer drug carriers Int J Pharm 373 165 173 1:CAS:528:DC%2BD1MXltlSjtrw%3D 10.1016/j.ijpharm.2009.02.012 19429302