Synthesis of new nonclassical acridines, quinolines, and quinazolines derived from dimedone for biological evaluation

Archiv der Pharmazie

Volumn 343, Issue 9, 2010, Pages 519-527

  El Sabbagh, Osama I ^a   Shabaan, Mohamed A ^b   Kadry, Hanan H ^b   Al Din, Ehab Saad ^c  

^a Zagazig University   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c Al Azhar University   (Egypt)

Author keywords

Acridines; Antimicrobial; Cytotoxic activity; Quinazolines; Quinolines

Indexed keywords

10 (4 CHLOROPHENYL) 9 (2 THIENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; 10 (4 CHLOROPHENYL) 9 (2,4-DICHLOROPHENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; 10 (4 CHLOROPHENYL) 9 (3 NITROPHENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; 10 (4 CHLOROPHENYL) 9 (4 FLUOROPHENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; 10 (4 CHLOROPHENYL) 9 (4 METHYLPHENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; 2 AMINO 1 (4 CHLOROPHENYL) 4 (2,4 DICHLOROPHENYL) 7,7 DIMETHYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 4 (4 METHOXYPHENYL) 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 4 (4 METHYLPHENYL) 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 4 PHENYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 4 (2 CHLOROPHENYL) 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 4 (3 BROMOPHENYL) 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 4 (4 BROMOPHENYL) 1 (4 CHLOROPHENYL) 7,7DIMETHYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 2 AMINO 4 (4 CHLOROPHENYL) 1 (4 CHLOROPHENYL) 7,7 DIMETHYL 1,4,5,6,7,8 HEXAHYDROQUINOLIN 5 ONE; 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; 9 (4 BROMOPHENYL) 10 (4 CHLOROPHENYL) 3,3,6,6 TETRAMETHYL 1,2,3,4,5,6,7,8,9,10 DECAHYDROACRIDIN 1,8 DIONE; ACRIDINE DERIVATIVE; CIPROFLOXACIN; DIKETONE; NYSTATIN; QUINAZOLINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOMA CELL; CELL VIABILITY; CONTROLLED STUDY; DISK DIFFUSION; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; LIVER CARCINOMA; NONHUMAN; PRIORITY JOURNAL;

ACRIDINES; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CYCLOHEXANONES; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MICROBIAL SENSITIVITY TESTS; QUINAZOLINES; QUINOLINES;

EID: 77956852060     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900296     Document Type: Article

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