Synthesis of 4-aryl-7,7-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2- one/thione-5-one derivatives and evaluation as antibacterials

European Journal of Medicinal Chemistry

Volumn 40, Issue 8, 2005, Pages 816-819

  Kidwai, M ^a   Saxena, S ^a   Khalilur Rahman Khan, M ^b   Thukral, S S ^b  

^a UNIVERSITY OF DELHI   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Antibacterial activity; Microwave irradiation; Quinazolines; Solvent free

Indexed keywords

4 (2 CHLORO 3 QUINOLYL) 7,7 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2 DIONE; 4 (2 CHLORO 3 QUINOLYL) 7,7 DIMETHYL 5 OXO 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2 THIONE; 4 (4 CHLOROPHENYL) 7,7 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2,5 DIONE; 4 (4 CHLOROPHENYL) 7,7 DIMETHYL 5 OXO 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2 THIONE; 4 PHENYL 7,7 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2,5 DIONE; 4 PHENYL 7,7 DIMETHYL 5 OXO 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2,5 THIONE; 4 PIPERONYL 7,7 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2 DIONE; 4 PIPERONYL 7,7 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2,5 DIONE; 4 PIPERONYL 7,7 DIMETHYL 5 OXO 1,2,3,4,5,6,7,8 OCTAHYDROQUINAZOLINE 2 THIONE; ANTIINFECTIVE AGENT; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ESCHERICHIA COLI; MICROWAVE IRRADIATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; MICROBIAL SENSITIVITY TESTS; NORFLOXACIN; QUINAZOLINES;

EID: 23944504818     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.02.009     Document Type: Article

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