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Volumn 15, Issue 4, 2010, Pages 537-553

Antiretroviral drugs to prevent breastfeeding HIV transmission

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; COTRIMOXAZOLE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NEVIRAPINE; PLACEBO; STAVUDINE; TENOFOVIR; ZIDOVUDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 77956851018     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: 10.3851/IMP1574     Document Type: Review
Times cited : (50)

References (51)
  • 1
    • 77951065603 scopus 로고    scopus 로고
    • WHO. Geneva: UNAIDS, WHO 2009. Updated 25 November Accessed 4 May 2010. Available from
    • UNAIDS, WHO. AIDS epidemic update: November 2009. Geneva: UNAIDS, WHO 2009. (Updated 25 November 2009. Accessed 4 May 2010.) Available from http://data.unaids.org/pub/Report/2009/2009-epidemic-update-en.pdf
    • (2009) AIDS Epidemic Update: November 2009
  • 2
    • 33947582476 scopus 로고    scopus 로고
    • Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: An intervention cohort study
    • Coovadia HM, Rollins NC, Bland RM, et al. Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study. Lancet 2007; 369:1107-1116.
    • (2007) Lancet , vol.369 , pp. 1107-1116
    • Coovadia, H.M.1    Rollins, N.C.2    Bland, R.M.3
  • 3
    • 44449084384 scopus 로고    scopus 로고
    • High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission
    • Kuhn L, Sinkala M, Kankasa C, et al. High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission. PLoS ONE 2007; 2:e1363.
    • (2007) PLoS ONE , vol.2
    • Kuhn, L.1    Sinkala, M.2    Kankasa, C.3
  • 4
    • 43249104646 scopus 로고    scopus 로고
    • Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006
    • Townsend CL, Cortina-Borja M, Peckham CS, de Ruiter A, Lyall H, Tookey PA. Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. AIDS 2008; 22:973-981.
    • (2008) AIDS , vol.22 , pp. 973-981
    • Townsend, C.L.1    Cortina-Borja, M.2    Peckham, C.S.3    De Ruiter, A.4    Lyall, H.5    Tookey, P.A.6
  • 5
    • 77956792668 scopus 로고    scopus 로고
    • Updated 10 December Accessed 26 November 2009. Available from
    • UNICEF. Children and HIV and AIDS. (Updated 10 December 2009. Accessed 26 November 2009.) Available from http://www.unicef.org/aids/index.php
    • (2009) Children and HIV and AIDS
  • 11
    • 69549110329 scopus 로고    scopus 로고
    • Predictors of early and late mother-to-child transmission of HIV in a breastfeeding population: HIV Network for Prevention Trials 012 experience, Kampala, Uganda
    • Mmiro FA, Aizire J, Mwatha AK, et al. Predictors of early and late mother-to-child transmission of HIV in a breastfeeding population: HIV Network for Prevention Trials 012 experience, Kampala, Uganda. J Acquir Immune Defic Syndr 2009; 52:32-39.
    • (2009) J Acquir Immune Defic Syndr , vol.52 , pp. 32-39
    • Mmiro, F.A.1    Aizire, J.2    Mwatha, A.K.3
  • 12
    • 72049128292 scopus 로고    scopus 로고
    • Universal antiretroviral therapy for pregnant and breast-feeding HIV-1-infected women: Towards the elimination of mother-to-child transmission of HIV-1 in resource-limited settings
    • Becquet R, Ekouevi DK, Arrive E, et al. Universal antiretroviral therapy for pregnant and breast-feeding HIV-1-infected women: towards the elimination of mother-to-child transmission of HIV-1 in resource-limited settings. Clin Infect Dis 2009; 49:1936-1945.
    • (2009) Clin Infect Dis , vol.49 , pp. 1936-1945
    • Becquet, R.1    Ekouevi, D.K.2    Arrive, E.3
  • 14
    • 44949186716 scopus 로고    scopus 로고
    • Risk factors for late postnatal transmission of human immunodeficiency virus type 1 in sub-Saharan Africa
    • Chasela C, Chen YQ, Fiscus S, et al. Risk factors for late postnatal transmission of human immunodeficiency virus type 1 in sub-Saharan Africa. Pediatr Infect Dis J 2008; 27:251-256.
    • (2008) Pediatr Infect Dis J , vol.27 , pp. 251-256
    • Chasela, C.1    Chen, Y.Q.2    Fiscus, S.3
  • 15
    • 2942560763 scopus 로고    scopus 로고
    • Late postnatal transmission of HIV-1 in breast-fed children: An individual patient data metaanalysis
    • The Breastfeeding and HIV International Transmission Study Group
    • The Breastfeeding and HIV International Transmission Study Group. Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data metaanalysis. J Infect Dis 2004; 189:2154-2166.
    • (2004) J Infect Dis , vol.189 , pp. 2154-2166
  • 16
    • 77952923689 scopus 로고    scopus 로고
    • Potential impact of new World Health Organization criteria for antiretroviral treatment for prevention of mother to child HIV transmission
    • Kuhn L, Aldrovandi G, Sinkala M, et al. Potential impact of new World Health Organization criteria for antiretroviral treatment for prevention of mother to child HIV transmission. AIDS 2010; 24:1374-1377.
    • (2010) AIDS , vol.24 , pp. 1374-1377
    • Kuhn, L.1    Aldrovandi, G.2    Sinkala, M.3
  • 17
    • 65649117674 scopus 로고    scopus 로고
    • Comparison of CD4 cell count, viral load and other markers for prediction of mortality among HIV-1-infected Kenyan pregnant women
    • Brown ER, Otieno P, Mbori-Ngacha DA, et al. Comparison of CD4 cell count, viral load and other markers for prediction of mortality among HIV-1-infected Kenyan pregnant women. J Infect Dis 2009; 199:1292-1300.
    • (2009) J Infect Dis , vol.199 , pp. 1292-1300
    • Brown, E.R.1    Otieno, P.2    Mbori-Ngacha, D.A.3
  • 18
    • 77956819445 scopus 로고    scopus 로고
    • Comparing clinical and immunologic criteria for determining HAART eligibility among HIV-infected pregnant and postpartum women in low resource settings
    • Abstract O15
    • Dugan K, Carter R, Toro P, et al. Comparing clinical and immunologic criteria for determining HAART eligibility among HIV-infected pregnant and postpartum women in low resource settings. 1st International Workshop on HIV Pediatrics. 17-18 July 2009, Capetown, South Africa. Abstract O15.
    • 1st International Workshop on HIV Pediatrics. 17-18 July 2009, Capetown, South Africa
    • Dugan, K.1    Carter, R.2    Toro, P.3
  • 19
    • 37549010323 scopus 로고    scopus 로고
    • Variation of CD4 count and percentage during pregnancy and after delivery: Implications for HAART initiation in resource-limited settings
    • Ekouevi DK, Inwoley A, Tonwe-Gold B, et al. Variation of CD4 count and percentage during pregnancy and after delivery: implications for HAART initiation in resource-limited settings. AIDS Res Hum Retroviruses 2007; 23:1469-1474.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 1469-1474
    • Ekouevi, D.K.1    Inwoley, A.2    Tonwe-Gold, B.3
  • 20
    • 33747099592 scopus 로고    scopus 로고
    • Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: A randomized trial: The Mashi Study
    • Thior I, Lockman S, Smeaton LM, et al. Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study. JAMA 2006; 296:794-805.
    • (2006) JAMA , vol.296 , pp. 794-805
    • Thior, I.1    Lockman, S.2    Smeaton, L.M.3
  • 21
    • 47049086842 scopus 로고    scopus 로고
    • Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating infants prophylactically with lamivudine in Dar es Salaam, Tanzania: The Mitra Study
    • Kilewo C, Karlsson K, Massawe A, et al. Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating infants prophylactically with lamivudine in Dar es Salaam, Tanzania: the Mitra Study. J Acquir Immune Defic Syndr 2008; 48:315-323.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 315-323
    • Kilewo, C.1    Karlsson, K.2    Massawe, A.3
  • 23
    • 77649211938 scopus 로고    scopus 로고
    • Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: An analysis of three randomised controlled trials
    • Six Week Extended-Dose Nevirapine (SWEN) Study Team
    • Six Week Extended-Dose Nevirapine (SWEN) Study Team. Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomised controlled trials. Lancet 2008; 372:300-313.
    • (2008) Lancet , vol.372 , pp. 300-313
  • 24
    • 46949108668 scopus 로고    scopus 로고
    • Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission
    • Kumwenda NI, Hoover DR, Mofenson LM, et al. Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission. N Engl J Med 2008; 359:119-129.
    • (2008) N Engl J Med , vol.359 , pp. 119-129
    • Kumwenda, N.I.1    Hoover, D.R.2    Mofenson, L.M.3
  • 25
    • 77953723667 scopus 로고    scopus 로고
    • Maternal or infant antiretroviral drugs to reduce HIV-1 transmission
    • Chasela CS, Hudgens MG, Jaimeson DJ, et al. Maternal or infant antiretroviral drugs to reduce HIV-1 transmission. N Engl J Med 2010; 362:2271-2281.
    • (2010) N Engl J Med , vol.362 , pp. 2271-2281
    • Chasela, C.S.1    Hudgens, M.G.2    Jaimeson, D.J.3
  • 26
    • 34447300390 scopus 로고    scopus 로고
    • Implementing antiretroviral triple therapy to prevent HIV mother-to-child transmission: A public health approach in resource-limited settings
    • Marazzi CM, Germano P, Liotta G, et al. Implementing antiretroviral triple therapy to prevent HIV mother-to-child transmission: a public health approach in resource-limited settings. Eur J Pediatr 2007; 166:1305-1307.
    • (2007) Eur J Pediatr , vol.166 , pp. 1305-1307
    • Marazzi, C.M.1    Germano, P.2    Liotta, G.3
  • 27
    • 34447315041 scopus 로고    scopus 로고
    • Treatment acceleration program and the experience of the DREAM program in prevention of mother-to-child transmission of HIV
    • Palombi L, Marazzi MC, Voetberg A, Magid NA. Treatment acceleration program and the experience of the DREAM program in prevention of mother-to-child transmission of HIV. AIDS 2007; 21 Suppl 4:S65-S71.
    • (2007) AIDS , vol.21 , Issue.SUPPL. 4
    • Palombi, L.1    Marazzi, M.C.2    Voetberg, A.3    Magid, N.A.4
  • 29
    • 70350548085 scopus 로고    scopus 로고
    • Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating mothers with triple antiretroviral therapy in Dar es Salaam, Tanzania: The MITRA PLUS Study
    • Kilewo C, Karlsson K, Ngarina M, et al. Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating mothers with triple antiretroviral therapy in Dar es Salaam, Tanzania: the MITRA PLUS Study. J Acquir Immune Defic Syndr 2009; 52:406-416.
    • (2009) J Acquir Immune Defic Syndr , vol.52 , pp. 406-416
    • Kilewo, C.1    Karlsson, K.2    Ngarina, M.3
  • 30
    • 72049113250 scopus 로고    scopus 로고
    • Breastfeeding with maternal antiretroviral therapy or formula feeding to prevent HIV postnatal mother to child infection in Rwanda
    • Peltier CA, Ndayisaba GF, Lepage P, et al. Breastfeeding with maternal antiretroviral therapy or formula feeding to prevent HIV postnatal mother to child infection in Rwanda. AIDS 2009; 23:2415-2423.
    • (2009) AIDS , vol.23 , pp. 2415-2423
    • Peltier, C.A.1    Ndayisaba, G.F.2    Lepage, P.3
  • 31
    • 85031344688 scopus 로고    scopus 로고
    • Triple-antiretroviral prophylaxis during pregnancy and breastfeeding compared to short-ARV prophylaxis to prevent mother-to-child transmission of HIV-1: The Kesho Bora randomized controlled clinical trial in five sites in Burkina Faso, Kenya and South Africa
    • the Kesho Bora Study Group. Abstract LBPE C01
    • de Vincenzi I, the Kesho Bora Study Group. Triple-antiretroviral prophylaxis during pregnancy and breastfeeding compared to short-ARV prophylaxis to prevent mother-to-child transmission of HIV-1: the Kesho Bora randomized controlled clinical trial in five sites in Burkina Faso, Kenya and South Africa. 5th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. 19-22 July 2009, Cape Town, South Africa. Abstract LBPE C01.
    • 5th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. 19-22 July 2009, Cape Town, South Africa
    • De Vincenzi, I.1
  • 32
    • 77953725982 scopus 로고    scopus 로고
    • Antiretroviral regimens in pregnancy and breastfeeding in Botswana
    • Shapiro RL, Hughes MD, Ogwu A, et al. Antiretroviral regimens in pregnancy and breastfeeding in Botswana. N Engl J Med 2010; 362:2282-2294.
    • (2010) N Engl J Med , vol.362 , pp. 2282-2294
    • Shapiro, R.L.1    Hughes, M.D.2    Ogwu, A.3
  • 33
    • 0034606875 scopus 로고    scopus 로고
    • Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: A pooled analysis
    • WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality
    • WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality. Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. Lancet 2000; 355:451-455.
    • (2000) Lancet , vol.355 , pp. 451-455
  • 34
    • 17144394506 scopus 로고    scopus 로고
    • Potential cost-effectiveness of maternal and infant antiretroviral interventions to prevent mother-to-child transmission during breastfeeding
    • Maclean CC, Stringer JSA. Potential cost-effectiveness of maternal and infant antiretroviral interventions to prevent mother-to-child transmission during breastfeeding. J Acquir Immune Defic Syndr 2005; 38:570-577.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , pp. 570-577
    • Maclean, C.C.1    Stringer, J.S.A.2
  • 35
    • 59849097134 scopus 로고    scopus 로고
    • Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire
    • Ekouevi DK, Coffie PA, Becquet R, et al. Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire. AIDS 2008; 22:1815-1820.
    • (2008) AIDS , vol.22 , pp. 1815-1820
    • Ekouevi, D.K.1    Coffie, P.A.2    Becquet, R.3
  • 37
    • 34247590332 scopus 로고    scopus 로고
    • Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland
    • DOI 10.1097/QAD.0b013e328133884b, PII 0000203020070511000015
    • Townsend CL, Cortina-Borja M, Peckham CS, Tookey PA. Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland. AIDS 2007; 21:1019-1026. (Pubitemid 46684333)
    • (2007) AIDS , vol.21 , Issue.8 , pp. 1019-1026
    • Townsend, C.L.1    Cortina-Borja, M.2    Peckham, C.S.3    Tookey, P.A.4
  • 38
    • 33847238368 scopus 로고    scopus 로고
    • Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: A meta-analysis
    • DOI 10.1097/QAD.0b013e32802ef2f6, PII 0000203020070312000007
    • Kourtis AP, Schmid CH, Jamieson DJ, Lau J. Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: a meta-analysis. AIDS 2007; 21:607-615. (Pubitemid 46303654)
    • (2007) AIDS , vol.21 , Issue.5 , pp. 607-615
    • Kourtis, A.P.1    Schmid, C.H.2    Jamieson, D.J.3    Lau, J.4
  • 39
    • 58149464331 scopus 로고    scopus 로고
    • Nevirapine resistance and breast-milk HIV transmission: Effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants
    • Moorthy A, Gupta A, Bhosale R. Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants. PLoS ONE 2009; 4:e4096.
    • (2009) PLoS ONE , vol.4
    • Moorthy, A.1    Gupta, A.2    Bhosale, R.3
  • 40
    • 75649130394 scopus 로고    scopus 로고
    • Addition of extended zidovudine to extended nevirapine prophylaxis reduces nevirapine resistance in infants who were HIV-infected in utero
    • Lidstrom J, Li Q, Hoover DR, et al. Addition of extended zidovudine to extended nevirapine prophylaxis reduces nevirapine resistance in infants who were HIV-infected in utero. AIDS 2010; 24:381-386.
    • (2010) AIDS , vol.24 , pp. 381-386
    • Lidstrom, J.1    Li, Q.2    Hoover, D.R.3
  • 41
    • 77956799366 scopus 로고    scopus 로고
    • Emergence of HIV-1 drug resistance among breastfeeding infants born to HIV-infected mothers taking antiretrovirals for prevention of mother-to-child transmission of HIV: The Kisumu Breastfeeding Study, Kenya
    • Abstract 84LB
    • Zeh C, Weidle P, Nafisa L, et al. Emergence of HIV-1 drug resistance among breastfeeding infants born to HIV-infected mothers taking antiretrovirals for prevention of mother-to-child transmission of HIV: the Kisumu Breastfeeding Study, Kenya. 15th Conference on Retroviruses and Opportunistic Infections. 3-6 February 2008, Boston, MA, USA. Abstract 84LB.
    • 15th Conference on Retroviruses and Opportunistic Infections. 3-6 February 2008, Boston, MA, USA
    • Zeh, C.1    Weidle, P.2    Nafisa, L.3
  • 42
    • 70849123399 scopus 로고    scopus 로고
    • Antiretroviral treatment of HIV-infected women can induce multi-class drug resistance in their breastfeeding infants
    • Lidstrom J, Kumwenda N, Kafulafula G, et al. Antiretroviral treatment of HIV-infected women can induce multi-class drug resistance in their breastfeeding infants. Antivir Ther 2009; 14 Suppl 1:A158.
    • (2009) Antivir Ther , vol.14 , Issue.SUPPL. 1
    • Lidstrom, J.1    Kumwenda, N.2    Kafulafula, G.3
  • 44
    • 62949168283 scopus 로고    scopus 로고
    • Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy
    • Mirochnick M, Thomas T, Capparelli E, et al. Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy. Antimicrob Agents Chemother 2009; 53:1170-1176.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1170-1176
    • Mirochnick, M.1    Thomas, T.2    Capparelli, E.3
  • 45
    • 27544486218 scopus 로고    scopus 로고
    • The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk
    • Colebunders R, Hodossy B, Burger D, et al. The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk. AIDS 2005; 19:1912-1915.
    • (2005) AIDS , vol.19 , pp. 1912-1915
    • Colebunders, R.1    Hodossy, B.2    Burger, D.3
  • 46
    • 46949105035 scopus 로고    scopus 로고
    • Effects of early, abrupt weaning on HIV-free survival of children in Zambia
    • Kuhn L, Aldrovandi GM, Sinkala M, et al. Effects of early, abrupt weaning on HIV-free survival of children in Zambia. N Engl J Med 2008; 359:130-141.
    • (2008) N Engl J Med , vol.359 , pp. 130-141
    • Kuhn, L.1    Aldrovandi, G.M.2    Sinkala, M.3
  • 47
    • 74049105664 scopus 로고    scopus 로고
    • Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi
    • Kafulafula G, Hoover D, Taha TE, et al. Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi. J Acquir Immune Defic Syndr 2010; 53:6-13.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 6-13
    • Kafulafula, G.1    Hoover, D.2    Taha, T.E.3
  • 48
    • 74049098671 scopus 로고    scopus 로고
    • Breastfeeding, mother-to-child HIV transmission, and mortality among infants born to hiv-infected women on highly active antiretroviral therapy in rural Uganda
    • Homsy J, Moore D, Barasa A, et al. Breastfeeding, mother-to-child HIV transmission, and mortality among infants born to hiv-infected women on highly active antiretroviral therapy in rural Uganda. J Acquir Immune Defic Syndr 2010; 53:28-35.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 28-35
    • Homsy, J.1    Moore, D.2    Barasa, A.3
  • 50
    • 74049148890 scopus 로고    scopus 로고
    • Hospitalization and mortality among primarily nonbreastfed children during a large outbreak of diarrhea and malnutrition in Botswana, 2006
    • Creek TL, Kim A, Lu L, et al. Hospitalization and mortality among primarily nonbreastfed children during a large outbreak of diarrhea and malnutrition in Botswana, 2006. J Acquir Immune Defic Syndr 2010; 53:14-19.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 14-19
    • Creek, T.L.1    Kim, A.2    Lu, L.3
  • 51
    • 77956001742 scopus 로고    scopus 로고
    • Geneva: WHO 2009. Updated 30 November Accessed 4 May 2010. Available from
    • WHO. Rapid advice: infant feeding in the context of HIV - November 2009. Geneva: WHO 2009. (Updated 30 November 2009. Accessed 4 May 2010.) Available from http://www.who.int/hiv/pub/paediatric/advice/en
    • (2009) Rapid Advice: Infant Feeding in the Context of HIV - November 2009


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