The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk

AIDS

Volumn 19, Issue 16, 2005, Pages 1912-1915

  Colebunders, Robert ^a,b   Hodossy, Beata ^a   Burger, David ^c   Daems, Tania ^b   Roelens, Kristien ^d   Coppens, Marc ^e   Van Bulck, Ben ^f   Jacquemyn, Yves ^b   Van Wijngaerden, Eric ^g   Fransen, Katrien ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

^e MIDDELHEIM HOSPITAL   (Belgium)

^f Stuivenberg General Hospital   (Belgium)

^g UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; INDINAVIR; NELFINAVIR; NEVIRAPINE; ZIDOVUDINE;

ADULT; ARTICLE; BREAST MILK; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EXCRETION; DRUG MILK LEVEL; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFORMED CONSENT; LYMPHOCYTE COUNT; PRIORITY JOURNAL; SAMPLE SIZE; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; VIRUS LOAD;

EID: 27544486218     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000188428.33280.41     Document Type: Article

References (6)

1. Musoke P, Guay LA, Bagenda D, Mirochnick M, Nakabiito C, Fleming T, et al. A phase I/II study of the safety and pharmacokinetics of nevirapine in HIV-1-infected pregnant Ugandan women and their neonates. AIDS 1999; 13:479-486.
2. Moodley J, Moodley D, Pillay K, Coovadia H, Saba J, van Leeuwen R, et al. Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring. I Infect Dis 1998; 178:1327-1333.
3. Ruff H, Hamzeh F, Lietman P. Excretion of zidovudine (ZDV) in human breast milk2E In: 34th Interscience Conference on Antimicrobial Agents and Chemotherapy. Orlando, FL, USA, 4-7 October 1994 [Abstract I11].
4. Hollanders RM, van Ewijk-Beneken Kolmer EW, Burger DM, Wuis EW, Koopmans PP, Hekster YA. Determination of nevirapine, an HIV-1 non-nucleoside reverse transcriptase inhibitor, in human plasma by reversed-phase high-performance liquid chromatography. J Chromatogr 2000; 744:65-71.
5. Droste JAH, Verweij-van Wissen CP, Burger DM. Simultaneous determination of the HIV drugs indinavir, amprenavir, saquinavir, ritonavir, lopinavir, nelfinavir, the nelfinavir hydroxymetabolite M8 and nevirapine in human plasma by reversed-phase high-performance liquid chromatography. Ther Drug Monit 2003; 25:393-399.
6. John GC, Nduati RW, Mbori-Ngacha DA, Richardson BA, Panteleeff D, Mwatha A, et al. Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA shedding, and breast infections. J Infect Dis 2001; 183:206-212.