Mitochondrial uncoupling downregulates calsequestrin expression and reduces SR Ca2+ stores in cardiomyocytes

Cardiovascular Research

Volumn 88, Issue 1, 2010, Pages 75-82

  Hänninen, Sandra L ^a   Ronkainen, Jarkko J ^a   Leskinen, Hanna ^b   Tavi, Pasi ^b  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Antioxidant therapy; Calcium release; E C coupling; Mitochondrial cardiomyopathy; ROS

Indexed keywords

ACETYLCYSTEINE; CALCIUM; CALSEQUESTRIN; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CASPASE 3; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

AGING; ANIMAL CELL; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM SIGNALING; CARDIOMYOPATHY; CELL CULTURE; CELL STRESS; CONFOCAL MICROSCOPY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; HEART MUSCLE CELL; MITOCHONDRION; NEWBORN; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOPLASMIC RETICULUM;

ACETYLCYSTEINE; ANIMALS; ANIMALS, NEWBORN; CALCIUM; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CASPASE 3; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FREE RADICAL SCAVENGERS; MICROSCOPY, CONFOCAL; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SARCOPLASMIC RETICULUM; TIME FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UNCOUPLING AGENTS;

EID: 77956850236     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq180     Document Type: Article

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