A critical review: An overview of genetic influence on dental caries

Oral Diseases

Volumn 16, Issue 7, 2010, Pages 613-623

  Werneck, R I ^a   Mira, M T ^a   Trevilatto, P C ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

dental caries; genetic epidemiology; genetics; inheritance; susceptibility

Indexed keywords

DENTAL CARIES; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC RESISTANCE; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; METHODOLOGY; NONHUMAN; OBSERVATIONAL STUDY; POPULATION GENETICS; PRIORITY JOURNAL; REVIEW;

DENTAL CARIES; ENVIRONMENT; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, GENETIC; RISK FACTORS; STREPTOCOCCUS MUTANS;

EID: 77956843574     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2010.01675.x     Document Type: Review

References (107)

1. Abel L, Demenais F (1988). Detection of major genes for susceptibility to leprosy and its subtypes in a Caribbean island: Desirade island. Am J Hum Genet 42 : 256 266.
2. Abel L, Vu DL, Oberti J et al (1995). Complex segregation analysis of leprosy in southern Vietnam. Genetic Epidemiol 12 : 63 82.
3. Acton RT, Dasanayake AP, Harrison RA et al (1999). Associations of MHC genes with levels of caries-inducing organisms and caries severity in African-American women. Hum Immunol 60 : 984 989.
4. Adair PM, Pine CM, Burnside G et al (2004). Familial and cultural perceptions and beliefs of oral hygiene and dietary practices among ethnically and socio-economically diverse groups. Commun Dent Health 21 : 102 111.
5. Alcais A, Alter A, Antoni G et al (2007). Stepwise replication identifies a low-producing lymphotoxin-[alpha] allele as a major risk factor for early-onset leprosy. Nat Genet 39 : 517 522.
6. Antunes JLF, Peres MA (2006). Fundamentos de Odontologia Epidemiologia da Saúde Bucal. Guanabara Koogan :
7. Bachrach F, Young M (1927). A comparison of the degree of resemblance in dental characters shown in pairs of twins of identical and fraternal types. Br Dent J XLVIII : 1293 1304.
8. Baghdadi JE, Orlova M, Alter A et al (2006). An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults. J Exp Med 203 : 1679 1684.
9. Bagherian A, Nematollahi H, Afshari J, Moheghi N (2008). Comparison of allele frequency for HLA-DR and HLA-DQ between patients with ECC and caries-free children. J Indian Soc Pedodont Prev Dent 26 : 18 21.
10. Bastos JL, Gigante DP, Peres KG, Nedel FB (2007). Social determinants of odontalgia in epidemiological studies: theoretical review and proposed conceptual model. Ciência Saúde Coletiva 12 : 1611 1621.
11. Beck J, Drake C (1975). Some epidemiologic evidence on the etiology of caries. Community Dent Oral Epidemiol 3 : 223 227.
12. Bedos C, Brodeur JM, Arpin S, Nicolau B (2005). Dental caries experience: a two-generation study. J Dent Res 84 : 931 936.
13. Bonecker M, Cleaton-Jones P (2003). Trends in dental caries in Latin American and Caribbean 5-6-and 11-13-year-old children: a systematic review. Community Dent Oral Epidemiol 31 : 152 157.
14. Book J, Grahnen H (1953). Clinical and genetic studies of dental caries. II. Parents and sibs of adult highly resistant propositi. Odontol Revy 4 : 1 53.
15. Boraas J, Messer L, Till M (1988). A genetic contribution to dental caries, occlusion, and morphology as demonstrated by twins reared apart. J Dent Res 67 : 1150 1155.
16. Bordoni N, Doño R, Manfredi C, Allegrotti I (1973). Prevalence of dental caries in twins. ASDC J Dent Children 40 : 440 443.
17. Brathall D, Hänsel P (2005). Cariogram-a multifactorial risk assessment model for multifactorial disease. Community Dent Oral Epidemiol 33 : 256 264.
18. Bretz W, Corby P, Hart T et al (2005a). Dental caries and microbial acid production in twins. Caries Res 39 : 168 172.
19. Bretz W, Corby P, Hart T et al (2005b). Longitudinal analysis of Heritability for dental caries traits. J Dent Res 84 : 1047 1051.
20. de Brito Junior R, Scarel-Caminaga R, Trevilatto P, de Souza A, Barros S (2004). Polymorphisms in the vitamin D receptor gene are associated with periodontal disease. J Periodontol 75 : 1090 1095. (Pubitemid 39276492)
21. Burt BA (1998). Prevention policies in the light of the changed distribution of dental caries. Acta Odontol Scand 56 : 179 186.
22. Burton PR, Tobin MD, Hopper JL (2005). Key concepts in genetic epidemiology. Lancet 366 : 941 51.
23. Cheryl S, Peter C, Paul F (2005). Characterization of Streptococcus mutans diversity by determining restriction fragment-length polymorphisms of the gtfB gene of isolates from 5-year-old children and their mothers. Antonie van Leeuwenhock 88 : 75 85.
24. Chesters R, Huntington E, Burchell C, Stephen K (1992). Effect of oral care habits on caries in adolescents. Caries Res 26 : 299 304.
25. Conry JP, Messer LB, Boraas JC, Aeppli DP, Bouchard TJJ (1993). Dental caries and treatment characteristics in human twins reared apart. Arch Oral Biol 38 : 937 943.
26. Cordell H, Clayton D (2005). Genetic association studies. Lancet 366 : 1121 1131.
27. Culp DJ, Quivey RQ, Bowen WH, Fallon MA, Pearson SK, Faustoferri R (2005). A mouse caries model and evaluation of aqp5-knockout mice. Caries Res 39 : 448 454.
28. Cury JA, Rebelo MAB, Del Bel Cury AA, Derbyshire MTVC, Tabchoury CPM (2000). Biochemical composition and cariogenicity of dental plaque formed in the presence of sucrose or glucose and fructose. Caries Res 34 : 491 497.
29. Dawn Teare M, Barrett J (2005). Genetic linkage studies. Lancet 366 : 1036 1044.
30. De Soet JJ, van Gemert-Schriks MC, Laine ML, van Amerongen WE, Morre SA, van Winkelhoff AJ (2008). Host and microbiological factors related to dental caries development. Caries Res 42 : 340 347.
31. Deeley K, Letra A, Rose EK et al (2008). Possible association of amelogenin to high caries experience in a Guatemalan-Mayan population. Caries Res 42 : 8 13.
32. Dye BA, Tan S, Smith V et al (2007). Trends in oral health status: United States, 1988-1994 and 1999-2004. Vital Health Statist 11 : 1 92.
33. Elston R, Stewart J (1971). A general model for the genetic analysis of pedigree data. Hum Hered 21 : 523 542.
34. Evans R, LO E, Darwell B (1993). Determinants of variation in dental caries experience in primary teeth of Hong Kong children aged 6-8 years. Community Dent Oral Epidemiol 21 : 1 3.
35. Fairpo C (1979). Total caries experience in monozygotic and like-sexed dizygotic twins of Caucasoid origin aged 5 to 15 years. Archiv Oral Biol 24 : 491 494.
36. Feathrstone J (2004). The continuum of dental caries-evidence for a dynamic disease process. J Dent Res 83 : c39.
37. Feitosa MF, Borecki I, Krieger H, Beiguelman B, Rao DC (1995). The genetic epidemiology of leprosy in a Brazilian population. J Hum Genet 56 : 1179 1185.
38. Fejerskov O (2004). Changing paradigms in concepts on dental caries: consequences for oral health care. Caries Res 38 : 182 189.
39. Fieschi C, Dupuis S, Catherinot E et al (2003). Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor beta1 deficiency: medical and immunological implications. J Exp Med 197 : 527 535.
40. Finn S, Caldwell R (1963). Dental caries in twins-I. A comparison of the caries experience of monoygotic twins, dizigotic twins and unrelated children. Archiv Oral Biol 8 : 571 585.
41. Gao XJ (1990). Dental caries in 280 pairs of same-sex twins. Zhonghua Kou Qiang Yi Xue Za Zhi 25 : 18 20.
42. Garn S, Rowe N, Cole P (1976a). Sibling similarities in dental caries. J Dent Res 55 : 914.
43. Garn SM, Rowe NH, Clark DC (1976b). Parent-child similarities in dental caries rates. J Dent Res 55 : 1129.
44. Garn SM, Rowe NH, Cole PE (1977). Husband-wife similarities in dental caries experience. J Dent Res 56 : 186.
45. Griffin S, Regnier E, Griffin P, Huntley V (2007). Effectiveness of fluoride in preventing caries in adults. J Dent Res 86 : 410 415.
46. Haile RWC, Iselius L, Fine PEM, Morton NE (1985). Segregation and linkage analysis of 72 leprosy pedigrees. Hum Hered 35 : 43 52.
47. Hassel T (1995). Genetic influences in caries and Periodontal diseases. Crit Rev Oral Biol Med 6 : 319 342.
48. Hopper JL, Bishop DT, Easton DF (2005). Population-based family studies in genetic epidemiology (Genetic Epidemiology 6). Lancet 336 : 1397 1406.
49. Horowitz S, Osborne R, DeGeorge F (1958). Caries experience in twins. Science 128 : 300 301.
50. Hunt HR, Hopper CA, Erwin WG (1944). Inheritance of susceptibility to caries in albino rats (Mus norvegicus). J Dent Res 23 : 385 401.
51. Hunt HR, Hopper CA, Rosen S (1955). Genetic factors in experimental rat caries. In : F SR, eds Advances in experimental caries research. Amer Assoc Adv Soc :
52. Kanamoto T, Nonaka K, Nakata M (1994). Genetic variation in experimental dental caries in four inbred strains of rats. Caries Res 28 : 156 160.
53. Keyes P (1960). The infectious and transmissable nature of experimental dental caries. Findings and implications. Archiv Oral Biol 13 : 304 320.
54. Keyes P (1962). Recent advantages in dental research. Int Dent J 12 : 443 64.
55. Klein H (1946). Dental caries (DMF) experience in relocated children exposed to water containing fluorine. J.A.D.A 33 : 1136 1141.
56. Klein H, Palmer C (1938). Studies on dental caries V. Familial resemblance in the caries experience of siblings. Public Health Rep 53 : 1353 1364.
57. Klein H, Palmer C (1940). Studies on dental caries: X. A procedure for the recording and statistical processing of dental examination findings. J Dent Res 19 : 243 256.
58. Krasse B (1996). The caries decline: is the effect of fluoride toothpaste overrated? Eur J Oral Sci 10 : 426 429.
59. Kurihara Y, Naito T, Obayashi K et al (1991). Caries susceptibility in inbred mouse strains and inheritance patterns in F1 and backcross (N2) progeny from strains with high and low caries susceptibility. Caries Res 25 : 341 346.
60. Lamb JR, Kontiainen S, Lehner T (1980). A comparative investigation of the generation of specific T cell-helper function induced by Streptococcus mutans in monkeys and mice. J Immunol 124 : 2384 2389.
61. Larson RH (1965). Response of Harvard caries-susceptible and caries-resistant rats to a severe cariogenic challenge. JDent Res 44 : 1402.
62. Larson RH, Keyes PH, Goss BJ (1968). Development of caries in the hunt-hoppert. caries-susceptible and caries-resistant rats under different experimental conditions. J Dent Res 47 : 704.
63. Lehner T, Lamb JR, Welsh KL, Batchelor RJ (1981). Association between HLA-DR antigens and helper cell activity in the control of dental caries. Nature 292 : 770 772.
64. Lenander-Lumikari M, Loimaranta V (2000). Saliva and dental caries. Adv Dent Res 14 : 40 47.
65. Liu H, Deng H, Cao CF, Ono H (1998). Genetic analysis of dental traits in 82 pairs of female-female twins. Chin J Dent Res 1 : 12 16.
66. Macrina FL, Dertzbaugh MT, Halula MC, Krah ER 3rd., Jones KR (1990). Genetic approaches to the study of oral microflora: a review. Crit Rev Oral Biol Med 1 : 207 227.
67. Maeda T, Takamori K, Shima M, Kurihara Y (1995). Effects of salivary immune response to Streptococcus mutans on caries occurrence and caries development in mice with autoimmune disease. J Nihon Univ School Dent 37 : 41 46.
68. Matsumoto N, Salam MA, Watanabe H, Amagasa T, Senpuku H (2004). Role of gene E2f1 in susceptibility to bacterial adherence of oral streptococci to tooth surfaces in mice. Oral Microbiol Immunol 19 : 270 276.
69. Mira MT (2006). Genetic host resistance and susceptibility to leprosy. Microbes Infect 8 : 1124 1131.
70. Mira MT, Alcais A, di Pietrantonio T et al (2003). Segregation of HLATNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes. Genes Immun 4 : 67 73.
71. Mira M, Alcaïs A, Nguyen V et al (2004). Susceptibility to leprosy is associated with PARK2 and PACRG. Nature 427 : 636 640.
72. Moraes M, Cardoso C, Vanderborght P, Pacheco A (2006). Genetics of host response in leprosy. Leprosy Rev 77 : 189 202.
73. Muhlemann H (1972). Karies und Parodontopathien beim Menschen in genetischer Sicht. Schweiz Monatsschr Zahnheilk 82 : 942 959.
74. Napimoga M, Höfling J, Klein M, Kamiya R, Gonalves R (2005). Transmission, diversity and virulence factors of Streptococcus mutans genotypes. J Oral Sci 47 : 59 64.
75. Nariyama M, Shimizu K, Uematsu T, Maeda T (2004). Identification of Chromossomes Associated with dental caries susceptibility using quantitative trait lócus analysis in mice. Caries Res 38 : 79 84.
76. NCBI (2009). RELEASE: NCBI dbSNP Build 129. NCBI : http://www.ncbi.nlm. nih.gov/projects/SNP/snp-summary.cgi.
77. Nobre dos Santos M, Melo dos Santos L, Francisco SB, Cury JA (2002). Relationship among dental plaque composition, daily sugar exposure and caries in the primary dentition. Caries Res 36 : 347 352.
78. Patir A, Seymen F, Yildirim M et al (2008). Enamel formation genes are associated with high caries experience in Turkish children. Caries Res 42 : 394 400.
79. Pehlivan S, Koturoglu G, Ozkinay F, Alpoz AR, Sipahi M, Pehlivan M (2005). Might there be a link between mannose-binding lectin polymorphism and dental caries? Mol Immunol 42 : 1125 1127.
80. Peres RCR, Camargo G, Mofatto LS et al (2009). Association of polymorphisms in the carbonic anhydrase 6 gene with salivary buffer capacity, dental plaque pH, and caries index in children aged 7-9 years. Pharmacogenom J. in press.
81. Petersen PE (2003). The World Oral Health Report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol 31 (Suppl 1 3 23.
82. Peterson P (2005). Sociobehavioural risk factors in dental caries-international perspectives. Community Dent Oral Epidemiol 33 : 274 279.
83. Pine C (2005). Caries risk: individual and population perspective. Community Dent Oral Epidemiol 33 : 239.
84. Quivey RG, Bowen WH, Fallon MA, Pearson SK, Faustoferri R (2005). A mouse caries model and evaluation of Aqp5-knockout mice. Caries Res 39 : 448 454.
85. Ranque B, Alcais A, Thuc N et al (2005). A recessive major gene controls the mitsuda reaction in a region endemic for leprosy. J Infect Dis 192 : 1475 1482.
86. Ranque B, Alter A, Mira M et al (2007). Genomewide linkage analysis of the granulomatous mitsuda reaction implicates chromosomal regions 2q35 and 17q21. J Infect Dis 196 : 1248 1252.
87. Remus N, El Baghdadi J, Fieschi C et al (2004). Association of IL12RB1 polymorphisms with pulmonary tuberculosis in adults in Morocco. J Infect Dis 190 : 580 587.
88. Risch N (2000). Searching for genetic determinants in the new millennium. Nature 405 : 847 856.
89. Department of Health and Human Services (2005). Preventing chronic diseases: investing Wisely in health. in : USA Department of Health and Human Services, ed. Centers for Disease Prevention and Health Promotion : http://www.cdc.gov/nccdphp/publications/factsheets/prevention/pdf/oh.pdf
90. Shuler C (2001). Inherite risks for susceptibility to dental caries. J Dent Educ 65 : 1038 1045.
91. Slayton R, Cooper M, Marazita M (2005). Tuftelin, mutans streptococci and dental caries susceptibility. J Dent Res 84 : 711 714.
92. Sofaer J (1993). Host genes and dental caries. Br Dent J 404 : 408.
93. Sørensen T, Nielsen G, Andersen P, Teasdale T (1988). Genetic and environmental influences on premature death in adult adoptees. N Engl J Med 318 : 727 732.
94. Souza AT, Trevilatto PC, Scarel-Caminaga RM, de Brito RB Jr., Barros SP, Lin SR (2005). Analysis of the MMP-9 (C-1562 T) and TIMP-2 (G-418C) gene promoter polymorphisms in patients with chronic periodontitis. J Clin Periodontol 32 : 207 211.
95. Steggerda M, Hill TJ (1936). Incidence of dental caries among Maya and Navajo Indians. J Dent Res 15 : 233.
96. Strachan T, Read AP (1999). Human Molecular Genetics 2. John Wiley & Sons, Inc :
97. Suzuki NK, Kurihara Y, Kurihara Y (1998). Dental caries susceptibility in mice is closely linked to the H-2 region on chromosome 17. Caries Res 32 : 262 265.
98. Thomas DC (2004). Statistical methods in genetic epidemiology. Oxford University Press :
99. Townsend G, Richards L, Hughes T, Pinkerton S, Schwerdt W (2003). The value of twins in dental research. Austral Dent J 48 : 82 88.
100. Townsend G, Hughes T, Luciano M, Bockmann M, Brook A (2008). Genetic and environmental influences on human dental variation: a critical evaluation of studies involving twins. Archiv Oral Biol 54 (Suppl 1): S45 S51.
101. Vieira AR, Marazita ML, Goldstein-McHenry T (2008). Genome-wide scan finds suggestive caries loci. J Dent Res 87 : 435 439.
102. Wagener DK, Schauf V, Nelson KE, Scollard D, Brown A, Smith T (1988). Segregation analysis of leprosy in families of Northen Thailand. Genetic Epidemiol 5 : 95 105.
103. Wen Z, Burne R (2002). Functional genomics approach to identify genes required for biofilm development by streptococcus mutans. Appl Environ Microbiol 68 : 1196 1203.
104. Willett N, Resnick J, Shaw J (1958). A comparison of the salivary protease activity in the Harvard and Hunt-Hoppert caries-resistant and caries-susceptible rats. J Dent Res 37 : 930 937.
105. World Health Organization (2004). WHO releases new report on global problem of oral diseases. WHO :
106. Yu PL, Bixler D, Goodman PA, Azen EA, Karn RC (1986). Human parotid proline-rich proteins: correlation of genetic polymorphisms to dental caries. Genetic Epidemiol 3 : 147 152.
107. Zakhary GM, Clark RM, Bidichandani SI, Owen WL, Slayton RL, Levine M (2007). Acidic proline-rich protein Db and caries in young children. J Dent Res 86 : 1176 1180.