Cancer-upregulated gene 2 (CUG2) overexpression induces apoptosis in SKOV-3 cells

Cell Biochemistry and Function

Volumn 28, Issue 6, 2010, Pages 461-468

  Lee, Soojin ^a   Lee, Sunhee ^a   Koh, Wansoo ^a   Kim, Hyun Taek ^a   Kim, Cheol Hee ^a  

^a Chungnam National University   (South Korea)

Author keywords

Apoptosis; Cancer upregulated gene 2; Oncogene; SKOV 3; Zebrafish

Indexed keywords

CASPASE 3; CASPASE 8; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER UPREGULATED GENE 2; CELL DEATH; CELL VIABILITY; CHROMOSOME ANALYSIS; CONTROLLED STUDY; CYTOPLASM; FLOW CYTOMETRY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MITOCHONDRION; OVARY CANCER; PRIORITY JOURNAL; TUMOR GENE; UPREGULATION; ZEBRA FISH;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; ZEBRAFISH;

DANIO RERIO;

EID: 77956841249     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1678     Document Type: Article

References (25)

1. Wiedemann LM, Morgan GJ. How are cancer associated genes activated or inactivated? Eur J Cancer 1992; 28: 248-251.
2. Vogelstein B, KinzlerKW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-799.
3. Varmus HE. Oncogenes and transcriptional control. Science 1987; 238: 1337-1339.
4. Green DR, McGahon A, Martin SJ. Regulation of apoptosis by oncogenes. J Cell Biochem 1996; 60: 33-38.
5. Labazi M, Phillips AC. Oncogenes as regulators of apoptosis. Essays Biochem 2003; 39: 89-104.
6. Harrington EA, Fanidi A, Evan GI. Oncogenes and cell death. Curr Opin Genet 1994; 4: 120-129.
7. Cox AD, Der CJ. The dark side of Ras: Regulation of apoptosis. Oncogene 2003; 22: 8999-9006.
8. Klampfer L, Swaby LA, Huang J, Sasazuki T, Shirasawa S, Augenlicht L. Oncogenic Ras increases sensitivity of colon cancer cells to 5-FUinduced apoptosis. Oncogene 2005; 24: 3932-3941.
9. Spandidos DA, Sourvinos G, Tsatsanis C, Zafiropoulos A. Normal ras genes: Their onco-suppressor and pro-apoptotic functions. Int J Oncol 2002; 21: 237-241.
10. Evan GI, Wyllie AH, Gilbert CS, et al., Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119-128.
11. Fuhrmann G, Rosenberger G, Grusch M, Klein N, Hofmann J, Krupitza G. The MYC dualism in growth and death. Mutat Res 1999; 437: 205-217.
12. Pelengaris S, Rudolph B, Littlewood T. Action of Myc in vivo - proliferation and apoptosis. Curr Opin Genet Dev 2000; 10: 100-105.
13. Lee S, Gang J, Jeon SB, et al., Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2). Biochem Biophys Res Commun 2007; 360: 633-639.
14. Kim H, Lee M, Lee S, et al., Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function. Mol Cells 2009; 27: 697-701.
15. Hori T, Amano M, Suzuki A, et al., CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore. Cell 2008; 135: 1039-1052.
16. Kim HT, Kim EH, Yoo KW, et al., Isolation and expression analysis of Alzheimer's disease-related gene xb51 in zebrafish. Dev Dyn 2008; 237: 3921-3926.
17. Aguilar-Quesada R, Munoz-Gamez JA, Martin-Oliva D, et al., Modulation of transcription by PARP-1: Consequences in carcinogenesis and inflammation. Curr Med Chem 2007; 14: 1179-1187.
18. Garrido C, Galluzzi L, Brunet M, Puig PE, Didelot C, Kroemer G. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 2006; 13: 1423-1433.
19. Eimon PM, Ashkenazi A. The zebrafish as a model organism for the study of apoptosis. Apoptosis 2010; 15: 331-349.
20. Negron JF, Lockshin RA. Activation of apoptosis and caspase-3 in zebrafish early gastrulae. Dev Dyn 2004; 231: 161-170.
21. Anand S, Penrhyn-Lowe S, Venkitaraman AR. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 2003; 3: 51-62.
22. Taborelli M, Tibiletti MG, Martin V, Pozzi B, Bertoni F, Capella C. Chromosome band 6q deletion pattern in malignant lymphomas. Cancer Genet Cytogenet 2006; 165: 106-113.
23. Tibiletti MG, Bernasconi B, Furlan D, et al., Chromosome 6 abnormalities in ovarian surface epithelial tumors of borderline malignancy suggest a genetic continuum in the progression model of ovarian neoplasms. Clin Cancer Res 2001; 7: 3404-3409.
24. Roberts CG, Tattersall MH. Cytogenetic study of solid ovarian tumors. Cancer Genet Cytogenet 1990; 48: 243-253.
25. Yonescu R, Currie JL, Hedrick L, Campbell J, Griffin CA. Chromosome abnormalities in primary endometrioid ovarian carcinoma. Cancer Genet Cytogenet 1996; 87: 167-171.