The transcription factor stua regulates central carbon metabolism, mycotoxin production, and effector gene expression in the wheat pathogen Stagonospora nodorum

Eukaryotic Cell

Volumn 9, Issue 7, 2010, Pages 1100-1108

  IpCho, Simon V S ^a   Tan, Kar Chun ^a   Koh, Geraldine ^a   Gummer, Joel ^a   Oliver, Richard P ^a   Trengove, Robert D ^a   Solomon, Peter S ^b  

^a MURDOCH UNIVERSITY   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; FUNGAL PROTEIN; MYCOTOXIN; TRANSCRIPTION FACTOR;

ARTICLE; ASCOMYCETES; BIOSYNTHESIS; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHENOTYPE; PLANT LEAF; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; WHEAT;

ASCOMYCOTA; CARBON; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; MYCOTOXINS; PHENOTYPE; PLANT LEAVES; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRITICUM;

PHAEOSPHAERIA NODORUM; TRITICUM AESTIVUM;

EID: 77956839098     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00064-10     Document Type: Article

References (35)

1. Aramayo, R., Y. Peleg, R. Addison, and R. Metzenberg. 1996. Asm-1+, aNeurospora crassa gene related to transcriptional regulators of fungal development. Genetics 144:991-1003.
2. Berg, J. M., J. L. Tymoczko, and L. Stryer. 2007. Biochemistry. W. H. Freeman and Company, New York, NY.
3. Busby, T. M., K. Y. Miller, and B. L. Miller. 1996. Suppression and enhancement of the Aspergillus nidulans medusa mutation by altered dosage of the bristle and stunted genes. Genetics 143:155-163.
4. Desbrosses, G. G., J. Kopka, and M. K. Udvardi. 2005. Lotus japonicus metabolic profiling. Development of gas chromatography-mass spectrometry resources for the study of plant-microbe interactions. Plant Physiol. 137:1302-1318.
5. Doedt, T., S. Krishnamurthy, D. P. Bockmuhl, B. Tebarth, C. Stempel, C. L. Russell, A. J. Brown, and J. F. Ernst. 2004. APSES proteins regulate morphogenesis and metabolism in Candida albicans. Mol. Biol. Cell 15:3167-3180.
6. Douaiher, M. N., P. Halama, and M. C. Janex-Favre. 2004. The ontogeny of Stagonospora nodorum pycnidia in culture. Sydowia 56:39-50.
7. Dutton, J. R., S. Johns, and B. L. Miller. 1997. StuAp is a sequence-specific transcription factor that regulates developmental complexity in Aspergillus nidulans. EMBO J. 16:5710-5721.
8. Friesen, T. L., E. H. Stukenbrock, Z. Liu, S. Meinhardt, H. Ling, J. D. Faris, J. B. Rasmussen, P. S. Solomon, B. A. McDonald, and R. P. Oliver. 2006. Emergence of a new disease as a result of interspecific virulence gene transfer. Nat. Genet. 38:953-956.
9. Friesen, T. L., Z. Zhang, P. S. Solomon, R. P. Oliver, and J. D. Faris. 2008. Characterization of the interaction of a novel Stagonospora nodorum hostselective toxin with a wheat susceptibility gene. Plant Physiol. 146:682-693.
10. Gravelat, F. N., T. Doedt, L. Y. Chiang, H. Liu, S. G. Filler, T. F. Patterson, and D. C. Sheppard. 2008. In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR. Infect. Immun. 76:3632-3639.
11. Joliffe, I. T. 2005. Principal component analysis. Springer-Verlag, New York, NY.
12. Liu, Z., J. D. Faris, R. P. Oliver, K. C. Tan, P. S. Solomon, M. C. McDonald, B. A. McDonald, A. Nunez, S. Lu, J. B. Rasmussen, and T. L. Friesen. 2009. SnTox3 acts in effector triggered susceptibility to induce disease on wheat carrying the Snn3 gene. PLoS Pathog. 5:e1000581.
13. Lowe, R. G., M. Lord, K. Rybak, R. D. Trengove, R. P. Oliver, and P. S. Solomon. 2008. A metabolomic approach to dissecting osmotic stress in the wheat pathogen Stagonospora nodorum. Fungal Genet. Biol. 45:1479-1486.
14. Lowe, R. G. T., M. Lord, K. Rybak, R. D. Trengove, R. P. Oliver, and P. S. Solomon. 2009. Trehalose biosynthesis is involved in sporulation of Stagonospora nodorum. Fungal Genet. Biol. 46:381-389.
15. Miller, K. Y., J. Wu, and B. L. Miller. 1992. StuA is required for cell pattern formation in Aspergillus. Genes Dev. 6:1770-1782.
16. Murray, G. M., and J. P. Brennan. 2009. Estimating disease losses to the Australian wheat industry. Australas. Plant Pathol. 38:558-570.
17. Nishimura, M., J. Fukada, A. Moriwaki, T. Fujikawa, M. Ohashi, T. Hibi, and N. Hayashi. 2009. Mstu1, an APSES transcription factor, is required for appressorium-mediated infection in Magnaporthe grisea. Biosci. Biotechnol. Biochem. 73:1779-1786.
18. Ohara, T., and T. Tsuge. 2004. FoSTUA, encoding a basic helix-loop-helix protein, differentially regulates development of three kinds of asexual spores, macroconidia, microconidia, and chlamydospores, in the fungal plant pathogen Fusarium oxysporum. Eukaryot. Cell 3:1412-1422.
19. Ruijter, G. J. G., M. Bax, H. Patel, S. J. Flitter, P. J. I. van de Vondervoort, R. P. de Vries, P. A. vanKuyk, and J. Visser. 2003. Mannitol is required for stress tolerance in Aspergillus niger conidiospores. Eukaryot. Cell 2:690-698.
20. Scherer, M., H. Wei, R. Liese, and R. Fischer. 2002. Aspergillus nidulans catalase-peroxidase gene (cpeA) is transcriptionally induced during sexual development through the transcription factor StuA. Eukaryot. Cell 1:725-735.
21. Sheppard, D. C., T. Doedt, L. Y. Chiang, H. S. Kim, D. Chen, W. C. Nierman, and S. G. Filler. 2005. The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence. Mol. Biol. Cell 16:5866-5879.
22. Solomon, P. S., S. V. S. Ipcho, J. K. Hane, K.-C. Tan, and R. P. Oliver. 2008. A quantitative PCR approach to determine gene copy number. Fungal Genet. Rep. 55:5-8.
23. Solomon, P. S., R. G. T. Lowe, K. C. Tan, O. D. C. Waters, and R. P. Oliver. 2006. Stagonospora nodorum: cause of stagonospora nodorum blotch of wheat. Mol. Plant Pathol. 7:147-156.
24. Solomon, P. S., K. Rybak, R. D. Trengove, and R. P. Oliver. 2006. Investigating the role of calcium/calmodulin-dependent protein kinases in Stagonospora nodorum. Mol. Microbiol. 62:367-381.
25. Solomon, P. S., K. C. Tan, and R. P. Oliver. 2005. Mannitol 1-phosphate metabolism is required for sporulation in planta of the wheat pathogen Stagonospora nodorum. Mol. Plant Microbe Interact. 18:110-115.
26. Solomon, P. S., K. C. Tan, P. Sanchez, R. M. Cooper, and R. P. Oliver. 2004. The disruption of a G subunit sheds new light on the pathogenicity of Stagonospora nodorum on wheat. Mol. Plant Microbe Interact. 17:456-466.
27. Solomon, P. S., S. W. Thomas, P. Spanu, and R. P. Oliver. 2003. The utilisation of di/tripeptides by Stagonospora nodorum is dispensable for wheat infection. Physiol. Mol. Plant Pathol. 63:191-199.
28. Solomon, P. S., O. D. C. Waters, C. I. Jörgens, R. G. T. Lowe, J. Rechberger, R. D. Trengove, and R. P. Oliver. 2006. Mannitol is required for asexual sporulation in the wheat pathogen Stagonospora nodorum (glume blotch). Biochem. J. 399:231-239.
29. Solomon, P. S., O. D. C. Waters, and R. P. Oliver. 2007. Decoding the mannitol enigma in filamentous fungi. Trends Microbiol. 15:257-262.
30. Solomon, P. S., O. D. C. Waters, J. Simmonds, R. M. Cooper, and R. P. Oliver. 2005. The Mak2 MAP kinase signal transduction pathway is required for pathogenicity in Stagonospora nodorum. Curr. Genet. 48:60-68.
31. Tan, K. C., J. L. Heazlewood, A. H. Millar, G. Thomson, R. P. Oliver, and P. S. Solomon. 2008. A signaling-regulated, short-chain dehydrogenase of Stagonospora nodorum regulates asexual development. Eukaryot. Cell 7:1916-1929.
32. Tan, K. C., R. D. Trengove, G. L. Maker, R. P. Oliver, and P. S. Solomon. 2009. Metabolite profiling identifies the mycotoxin alternariol in the pathogen Stagonospora nodorum. Metabolomics 5:330-335.
33. Tong, X., X. Zhang, K. M. Plummer, K. M. Stowell, P. A. Sullivan, and P. C. Farley. 2007. GcSTUA, an APSES transcription factor, is required for generation of appressorial turgor pressure and full pathogenicity of Glomerella cingulata. Mol. Plant Microbe Interact. 20:1102-1111.
34. Twumasi-Boateng, K., Y. Yu, D. Chen, F. N. Gravelat, W. C. Nierman, and D. C. Sheppard. 2009. Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatus. Eukaryot. Cell 8:104-115.
35. Wu, J., and B. L. Miller. 1997. Aspergillus asexual reproduction and sexual reproduction are differentially affected by transcriptional and translational mechanisms regulating stunted gene expression. Mol. Cell. Biol. 17:6191- 6201.