Fiber optic microneedles for transdermal light delivery: Ex vivo porcine skin penetration experiments

Journal of Biomechanical Engineering

Volumn 132, Issue 9, 2010, Pages

  Kosoglu, Mehmet A ^a   Hood, Robert L ^b   Chen, Ye ^a   Xu, Yong ^a   Rylander, Marissa Nichole ^c   Rylander, Christopher G ^c  

^a State University   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c Medical Center Boulevard   (United States)

Author keywords

Fiber optic; Laser hyperthermia; Microneedle; Silica; Skin penetration

Indexed keywords

AVERAGE DIAMETER; DISPLACEMENT PLOTS; EX-VIVO; HEAT SOURCES; HUMAN TISSUES; IN-VIVO; LIGHT DELIVERY; LIGHT PENETRATION; MELT DRAWING; MICRONEEDLE; MICRONEEDLES; MINIMALLY INVASIVE; PEAK FORCE; PIG SKIN; PORCINE SKIN; SHARP TIP; SKIN PENETRATION; TECHNICAL BARRIERS; TRANSDERMAL;

FIBER OPTICS; FIBERS; OPTICAL FIBERS; PHOTONICS; SILICA;

NEEDLES;

SILICON DIOXIDE; DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBER OPTICS; HEAT; IN VIVO STUDY; LASER; LIGHT ABSORPTION; MATHEMATICAL MODEL; MELANOMA; MELTING POINT; NONHUMAN; SKIN; SKIN PENETRATION; SWINE; ANIMAL; FEASIBILITY STUDY; HUMAN; INTRADERMAL DRUG ADMINISTRATION; LIGHT; METABOLISM; NEEDLE;

SUIDAE; SUS;

ADMINISTRATION, CUTANEOUS; ANIMALS; FEASIBILITY STUDIES; FIBER OPTIC TECHNOLOGY; HUMANS; LIGHT; NEEDLES; PHARMACEUTICAL PREPARATIONS; SKIN; SWINE;

EID: 77956806710     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4002192     Document Type: Article

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