Vascular differentiation of bone marrow stem cells is directed by a tunable three-dimensional matrix

Acta Biomaterialia

Volumn 6, Issue 9, 2010, Pages 3395-3403

  Zhang, Ge ^a   Drinnan, Charles T ^a   Geuss, Laura R ^a   Suggs, Laura J ^a  

^a The University of Texas at Austin   (United States)

Author keywords

Differentiation; Endothelial cell; Fibrin; Mesenchymal stem cell; Polyethylene glycol

Indexed keywords

BIOMECHANICS; ENDOTHELIAL CELLS; ENZYME ACTIVITY; GENE EXPRESSION; OLIGONUCLEOTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENES; STEM CELLS;

CELL PHENOTYPE; CELL-BE; CELL/B.E; CELL/BE; DIFFERENTIATION; ENDOTHELIAL-CELLS; FIBRIN; MATRIX; MESENCHYMAL STEM CELL; TUNABLES;

CELL CULTURE;

FIBRIN; FIBRINOGEN; MACROGOL; MACROGOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA MICROARRAY; ENDOTHELIUM CELL; FIBER; HEMATOPOIETIC STEM CELL; HYPOTHESIS; IMMUNOFLUORESCENCE TEST; IN VIVO CULTURE; MESENCHYMAL STEM CELL; MICROENVIRONMENT; NONHUMAN; PHENOTYPE; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; RAT; REGENERATIVE MEDICINE; ANGIOGENESIS; ANIMAL; BLOOD VESSEL; BONE MARROW CELL; CELL MEMBRANE; CELL SHAPE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; ELASTICITY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; SWINE; ULTRASTRUCTURE;

ANIMALS; BLOOD VESSELS; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL SHAPE; CELL TRANSDIFFERENTIATION; CELL-MATRIX JUNCTIONS; ELASTICITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR MATRIX; FIBRIN; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; POLYETHYLENE GLYCOLS; RATS; SUS SCROFA;

EID: 77956757133     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.03.019     Document Type: Article

References (35)

1. Kannan RY et al. The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review. Biomaterials 2005;26(14):1857-75.
2. Levenberg S et al. Engineering vascularized skeletal muscle tissue. Nat Biotechnol 2005;23(7):879-84.
3. Niklason LE et al. Functional arteries grown in vitro. Science 1999;284(5413):489-93.
4. Engler AJ et al. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J Cell Biol 2004;166(6):877-87.
5. Pittenger MF et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284(5411):143-7.
6. Barry FP, Murphy JM. Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 2004;36(4):568-84.
7. Makino S et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999;103(5):697-705.
8. Toma C et al. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002;105(1):93-8.
9. Al-Khaldi A et al. Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo. Gene Ther 2003;10(8):621-9.
10. Annabi B et al. Hypoxia promotes murine bone-marrow-derived stromal cell migration and tube formation. Stem Cells 2003;21(3):337-47.
11. Okuyama H et al. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxiainducible factor 1. J Biol Chem 2006;281(22):15554-63.
12. Ruger BM et al. Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation 2008;76(7):772-83.
13. Mosesson MW. Fibrinogen and fibrin structure and functions. J Thromb Haemost 2005;3(8):1894-904.
14. van Hinsbergh VW, Collen A, Koolwijk P. Role of fibrin matrix in angiogenesis. Ann NY Acad Sci 2001;936:426-37.
15. Davani S et al. Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model. Circulation 2003;108(Suppl. 1): II253-8.
16. Schachinger V et al. Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: Final 1-year results of the REPAIR-AMI trial. Eur Heart J 2006;27(23):2775-83.
17. O'Neill TJT et al. Mobilization of bone marrow-derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cells. Circ Res 2005;97(10):1027-35.
18. Murayama T et al. Determination of bone marrow-derived endothelial progenitor cell significance in angiogenic growth factor-induced neovascularization in vivo. Exp Hematol 2002;30(8):967-72.
19. Murry CE et al. Cellular therapies for myocardial infarct repair. Cold Spring Harbor Symp Quant Biol 2002;67:519-26.
20. Brey EM et al. Therapeutic neovascularization: contributions from bioengineering. Tissue Eng 2005;11(3/4): 567-84.
21. Zhang G et al. Enhancing efficacy of stem cell transplantation to the heart with a PEGylated fibrin biomatrix. Tissue Eng A 2008;14(6):1025-36.
22. + cell homing to the infarcted heart. Tissue Eng 2007;13(8):2063-71.
23. Zhang G, Suggs LJ. Matrices and scaffolds for drug delivery in vascular tissue engineering. Adv Drug Deliv Rev 2007;59(4/5): 360-73.
24. Zhang G et al. A PEGylated fibrin patch for mesenchymal stem cell delivery. Tissue Eng 2006;12(1):9-19.
25. Li F et al. Low-molecular-weight peptides derived from extracellular matrix as chemoattractants for primary endothelial cells. Endothelium 2004;11(3/4): 199-206.
26. Wieghaus KA et al. Small molecule inducers of angiogenesis for tissue engineering. Tissue Eng 2006;12(7):1903-13.
27. Collen A et al. Influence of fibrin structure on the formation and maintenance of capillary-like tubules by human microvascular endothelial cells. Angiogenesis 1998;2(2):153-65.
28. Bensaid W et al. A biodegradable fibrin scaffold for mesenchymal stem cell transplantation. Biomaterials 2003;24(14):2497-502.
29. Grassl ED, Oegema TR, Tranquillo RT. Fibrin as an alternative biopolymer to type-I collagen for the fabrication of a media equivalent. J Biomed Mater Res 2002;60(4):607-12.
30. Vailhe B et al. The formation of tubular structures by endothelial cells is under the control of fibrinolysis and mechanical factors. Angiogenesis 1998;2(4):331-44.
31. Vailhe B et al. In vitro angiogenesis is modulated by the mechanical properties of fibrin gels and is related to alpha (v) beta3 integrin localization. In Vitro Cell Dev Biol Anim 1997;33(10):763-73.
32. Liu H, Collins SF, Suggs LJ. Three-dimensional culture for expansion and differentiation of mouse embryonic stem cells. Biomaterials 2006;27(36):6004-14. (Pubitemid 44414972)
33. Nehls V, Herrmann R. The configuration of fibrin clots determines capillary morphogenesis and endothelial cell migration. Microvasc Res 1996;51(3):347-64.
34. Ghajar CM et al. Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation. Tissue Eng 2006;12(10):2875-88.
35. Roberts MJ, Bentley MD, Harris JM. Chemistry for peptide and protein PEGylation. Adv Drug Deliv Rev 2002;54(4):459-76.