Enrichment of ligands with molecular dockings and subsequent characterization for human alcohol dehydrogenase 3

Cellular and Molecular Life Sciences

Volumn 67, Issue 17, 2010, Pages 3005-3015

  Hellgren, Mikko ^a   Carlsson, Jonas ^b   Östberg, Linus J ^a   Staab, Claudia A ^a,c   Persson, Bengt ^a,b   Höög, Jan Olov ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Alcohol dehydrogenase; Enzyme kinetics; Inhibitors; Molecular docking; S Nitrosoglutathione; Virtual screening

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 3; CHOLIC ACID; FATTY ACID DERIVATIVE; GLUTATHIONE DERIVATIVE; UNCLASSIFIED DRUG; ADH1C PROTEIN, HUMAN; LIGAND; PROTEIN BINDING;

ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; LIGAND BINDING; MOLECULAR DOCKING; NONHUMAN; PROTEIN FUNCTION; SCORING SYSTEM; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; ISOLATION AND PURIFICATION; KINETICS; METABOLISM;

ALCOHOL DEHYDROGENASE; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING;

EID: 77956750158     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0370-2     Document Type: Article

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