-
1
-
-
41349099104
-
Cancer statistics
-
10.3322/CA.2007.0010. 18287387
-
Cancer statistics. A Jemal R Siegel E Ward Y Hao J Xu T Murray MJ Thun, CA Cancer J Clin 2008 58 2 71 96 10.3322/CA.2007.0010 18287387
-
(2008)
CA Cancer J Clin
, vol.58
, Issue.2
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
2
-
-
12144272554
-
Screening and detection of ovarian cancer
-
10.1016/j.jmwh.2004.10.002. 15637515
-
Screening and detection of ovarian cancer. G Breedlove C Busenhart, J Midwifery Womens Health 2005 50 1 51 54 10.1016/j.jmwh.2004.10.002 15637515
-
(2005)
J Midwifery Womens Health
, vol.50
, Issue.1
, pp. 51-54
-
-
Breedlove, G.1
Busenhart, C.2
-
3
-
-
26844457534
-
The distinctive nature of HER2-positive breast cancers
-
10.1056/NEJMp058197. 16236735
-
The distinctive nature of HER2-positive breast cancers. HJ Burstein, N Engl J Med 2005 353 16 1652 1654 10.1056/NEJMp058197 16236735
-
(2005)
N Engl J Med
, vol.353
, Issue.16
, pp. 1652-1654
-
-
Burstein, H.J.1
-
4
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
10.1126/science.2470152. 2470152
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. DJ Slamon W Godolphin LA Jones JA Holt SG Wong DE Keith WJ Levin SG Stuart J Udove A Ullrich, Science 1989 244 4905 707 712 10.1126/science.2470152 2470152
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
5
-
-
23844485690
-
HER2/neu oncoprotein overexpression in epithelial ovarian cancer: Evaluation of its prevalence and prognostic significance
-
10.1159/000086958. 16020953
-
HER2/neu oncoprotein overexpression in epithelial ovarian cancer: evaluation of its prevalence and prognostic significance. E Verri P Guglielmini M Puntoni L Perdelli A Papadia P Lorenzi A Rubagotti N Ragni F Boccardo, Oncology 2005 68 2-3 154 161 10.1159/000086958 16020953
-
(2005)
Oncology
, vol.68
, Issue.2-3
, pp. 154-161
-
-
Verri, E.1
Guglielmini, P.2
Puntoni, M.3
Perdelli, L.4
Papadia, A.5
Lorenzi, P.6
Rubagotti, A.7
Ragni, N.8
Boccardo, F.9
-
6
-
-
20244378677
-
Phase i clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
-
10.1200/JCO.2005.03.184. 15699478
-
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer. DB Agus MS Gordon C Taylor RB Natale B Karlan DS Mendelson MF Press DE Allison MX Sliwkowski G Lieberman, J Clin Oncol 2005 23 11 2534 2543 10.1200/JCO.2005.03.184 15699478
-
(2005)
J Clin Oncol
, vol.23
, Issue.11
, pp. 2534-2543
-
-
Agus, D.B.1
Gordon, M.S.2
Taylor, C.3
Natale, R.B.4
Karlan, B.5
Mendelson, D.S.6
Press, M.F.7
Allison, D.E.8
Sliwkowski, M.X.9
Lieberman, G.10
-
7
-
-
77953464877
-
Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics
-
10.1186/1757-2215-3-7. 20346177
-
Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics. JA Wilken KT Webster NJ Maihle, J Ovarian Res 2010 3 7 10.1186/1757-2215-3-7 20346177
-
(2010)
J Ovarian Res
, vol.3
, pp. 7
-
-
Wilken, J.A.1
Webster, K.T.2
Maihle, N.J.3
-
8
-
-
0642280765
-
Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2)
-
10.1038/sj.cr.7290149. 12643348
-
Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2). LS Cheng AP Liu JH Yang YQ Dong LW Li J Wang CC Wang J Liu, Cell Res 2003 13 1 35 48 10.1038/sj.cr.7290149 12643348
-
(2003)
Cell Res
, vol.13
, Issue.1
, pp. 35-48
-
-
Cheng, L.S.1
Liu, A.P.2
Yang, J.H.3
Dong, Y.Q.4
Li, L.W.5
Wang, J.6
Wang, C.C.7
Liu, J.8
-
9
-
-
33646089874
-
Codon optimization, expression, and characterization of an internalizing anti-ErbB2 single-chain antibody in Pichia pastoris
-
10.1016/j.pep.2005.11.014. 16403645
-
Codon optimization, expression, and characterization of an internalizing anti-ErbB2 single-chain antibody in Pichia pastoris. S Hu L Li J Qiao Y Guo L Cheng J Liu, Protein Expr Purif 2006 47 1 249 257 10.1016/j.pep.2005.11.014 16403645
-
(2006)
Protein Expr Purif
, vol.47
, Issue.1
, pp. 249-257
-
-
Hu, S.1
Li, L.2
Qiao, J.3
Guo, Y.4
Cheng, L.5
Liu, J.6
-
10
-
-
38549085296
-
Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism
-
10.1002/prot.21551. 17847085
-
Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism. S Hu Z Zhu L Li L Chang W Li L Cheng M Teng J Liu, Proteins 2008 70 3 938 949 10.1002/prot.21551 17847085
-
(2008)
Proteins
, vol.70
, Issue.3
, pp. 938-949
-
-
Hu, S.1
Zhu, Z.2
Li, L.3
Chang, L.4
Li, W.5
Cheng, L.6
Teng, M.7
Liu, J.8
-
11
-
-
68149119188
-
Crystallization and preliminary crystallographic studies of the single-chain variable fragment of antibody chA21 in complex with an N-terminal fragment of ErbB2
-
10.1107/S1744309109020107. 19574641
-
Crystallization and preliminary crystallographic studies of the single-chain variable fragment of antibody chA21 in complex with an N-terminal fragment of ErbB2. Y Liu H Zhou J Zhu Y Gao L Niu J Liu M Teng, Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 65 Pt 7 692 694 10.1107/S1744309109020107 19574641
-
(2009)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.65
, Issue.PART 7
, pp. 692-694
-
-
Liu, Y.1
Zhou, H.2
Zhu, J.3
Gao, Y.4
Niu, L.5
Liu, J.6
Teng, M.7
-
12
-
-
0037281458
-
Angiogenesis relates to estrogen receptor negativity, c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast
-
10.1177/106689690301100107. 12598915
-
Angiogenesis relates to estrogen receptor negativity, c-erbB-2 overexpression and early relapse in node-negative ductal carcinoma of the breast. MI Koukourakis C Manolas G Minopoulos A Giatromanolaki E Sivridis, Int J Surg Pathol 2003 11 1 29 34 10.1177/106689690301100107 12598915
-
(2003)
Int J Surg Pathol
, vol.11
, Issue.1
, pp. 29-34
-
-
Koukourakis, M.I.1
Manolas, C.2
Minopoulos, G.3
Giatromanolaki, A.4
Sivridis, E.5
-
13
-
-
0033393696
-
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis
-
10600838
-
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. KS Russell DF Stern PJ Polverini JR Bender, Am J Physiol 1999 277 6 Pt 2 2205 2211 10600838
-
(1999)
Am J Physiol
, vol.277
, Issue.6 PART 2
, pp. 82205-2211
-
-
Russell, K.S.1
Stern, D.F.2
Polverini, P.J.3
Bender, J.R.4
-
14
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
9403702
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. AM Petit J Rak MC Hung P Rockwell N Goldstein B Fendly RS Kerbel, Am J Pathol 1997 151 6 1523 1530 9403702
-
(1997)
Am J Pathol
, vol.151
, Issue.6
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
Rockwell, P.4
Goldstein, N.5
Fendly, B.6
Kerbel, R.S.7
-
15
-
-
53149148455
-
Icariin stimulates angiogenesis by activating the MEK/ERK-and PI3K/AKT/eNOS-dependent signal pathway in human endothelial cells
-
10.1016/j.bbrc.2008.09.001. 18789310
-
Icariin stimulates angiogenesis by activating the MEK/ERK-and PI3K/AKT/eNOS-dependent signal pathway in human endothelial cells. BH Chung CK Kim, Biochem Biophys Res Commun 2008 376 404 408 10.1016/j.bbrc.2008.09.001 18789310
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 404-408
-
-
Chung, B.H.1
Kim, C.K.2
-
16
-
-
77949434190
-
Anti-HER-2 engineering antibody ChA21 inhibits growth and induces apoptosis of SKOV-3 cells
-
Anti-HER-2 engineering antibody ChA21 inhibits growth and induces apoptosis of SKOV-3 cells. AL Zhang H Xue XG Ling Y Gao F Yang LS Cheng J Liu Q Wu, Journal of Experimental & Clinical Cancer Research 2010 29 23
-
(2010)
Journal of Experimental & Clinical Cancer Research
, vol.29
, pp. 23
-
-
Zhang, A.L.1
Xue, H.2
Ling, X.G.3
Gao, Y.4
Yang, F.5
Cheng, L.S.6
Liu, J.7
Wu, Q.8
-
17
-
-
33746093280
-
Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC
-
10.1016/j.intimp.2006.02.002. 16846832
-
Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC. S Liu X Luo D Li J Zhang D Qiu W Liu L She Z Yang, Int Immunopharmacol 2006 6 9 1387 1393 10.1016/j.intimp.2006.02.002 16846832
-
(2006)
Int Immunopharmacol
, vol.6
, Issue.9
, pp. 1387-1393
-
-
Liu, S.1
Luo, X.2
Li, D.3
Zhang, J.4
Qiu, D.5
Liu, W.6
She, L.7
Yang, Z.8
-
18
-
-
0030512898
-
Quantification of angiogenesis in solid human tumours: An international consensus on the methodology and criteria of evaluation
-
DOI 10.1016/S0959-8049(96)00379-6, PII S0959804996003796
-
Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. PB Vermeulen G Gasparini SB Fox M Toi L Martin P McCulloch F Pezzella G Viale N Weidner AL Harris, Eur J Cancer 1996 32 A 14 2474 2484 10.1016/S0959-8049(96)00379-6 (Pubitemid 27080786)
-
(1996)
European Journal of Cancer Part A
, vol.32
, Issue.14
, pp. 2474-2484
-
-
Vermeulen, P.E.1
Gasparini, G.2
Fox, S.B.3
Toi, M.4
Martin, L.5
McCulloch, P.6
Pezzella, F.7
Viale, G.8
Weidner, N.9
Harris, A.L.10
Dirix, L.Y.11
-
19
-
-
0033965483
-
Akt takes center stage in angiogenesis signaling
-
10625297
-
Akt takes center stage in angiogenesis signaling. S Dimmeler AM Zeiher, Circulation Research 2000 86 1 4 5 10625297
-
(2000)
Circulation Research
, vol.86
, Issue.1
, pp. 4-5
-
-
Dimmeler, S.1
Zeiher, A.M.2
-
20
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
10.1056/NEJM200103153441101. 11248153
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. DJ Slamon B Leyland-Jones S Shak H Fuchs V Paton A Bajamonde T Fleming W Eiermann J Wolter M Pegram, New England Journal of Medicine 2001 344 11 783 792 10.1056/NEJM200103153441101 11248153
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
-
21
-
-
74649083025
-
Targeting gastric cancer with trastuzumab: New clinical practice and innovative developments to overcome resistance
-
10.1245/s10434-009-0766-0. 19841980
-
Targeting gastric cancer with trastuzumab: new clinical practice and innovative developments to overcome resistance. DH Roukos, Ann Surg Oncol 2010 17 1 14 17 10.1245/s10434-009-0766-0 19841980
-
(2010)
Ann Surg Oncol
, vol.17
, Issue.1
, pp. 14-17
-
-
Roukos, D.H.1
-
22
-
-
74049094790
-
HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
-
10.1186/1471-2407-9-433. 20003286
-
HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy. JN McAlpine KC Wiegand R Vang BM Ronnett A Adamiak M Kobel SE Kalloger KD Swenerton DG Huntsman CB Gilks, Bmc Cancer 2009 9 433 10.1186/1471-2407-9-433 20003286
-
(2009)
Bmc Cancer
, vol.9
, pp. 433
-
-
McAlpine, J.N.1
Wiegand, K.C.2
Vang, R.3
Ronnett, B.M.4
Adamiak, A.5
Kobel, M.6
Kalloger, S.E.7
Swenerton, K.D.8
Huntsman, D.G.9
Gilks, C.B.10
-
23
-
-
58149231295
-
Ten years of HER2-directed therapy: Still questions after all these years
-
10.1007/s10549-008-0041-2. 18463974
-
Ten years of HER2-directed therapy: still questions after all these years. IE Krop EP Winer, Breast Cancer Res Treat 2009 113 2 207 209 10.1007/s10549-008-0041-2 18463974
-
(2009)
Breast Cancer Res Treat
, vol.113
, Issue.2
, pp. 207-209
-
-
Krop, I.E.1
Winer, E.P.2
-
24
-
-
3042672914
-
HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors
-
10.1158/1078-0432.CCR-03-0695. 15217943
-
HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors. KL Blackwell MW Dewhirst V Liotcheva S Snyder G Broadwater R Bentley A Lal G Riggins S Anderson J Vredenburgh, Clin Cancer Res 2004 10 12 Pt 1 4083 4088 10.1158/1078-0432.CCR-03- 0695 15217943
-
(2004)
Clin Cancer Res
, vol.10
, Issue.12 PART 1
, pp. 4083-4088
-
-
Blackwell, K.L.1
Dewhirst, M.W.2
Liotcheva, V.3
Snyder, S.4
Broadwater, G.5
Bentley, R.6
Lal, A.7
Riggins, G.8
Anderson, S.9
Vredenburgh, J.10
-
25
-
-
77953342817
-
HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer
-
10.1093/annonc/mdp532. 19940005
-
HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer. SF Schoppmann D Tamandl L Roberts G Jomrich A Schoppmann R Zwrtek P Dubsky M Gnant R Jakesz P Birner, Ann Oncol 2009 21 5 955 960 10.1093/annonc/mdp532 19940005
-
(2009)
Ann Oncol
, vol.21
, Issue.5
, pp. 955-960
-
-
Schoppmann, S.F.1
Tamandl, D.2
Roberts, L.3
Jomrich, G.4
Schoppmann, A.5
Zwrtek, R.6
Dubsky, P.7
Gnant, M.8
Jakesz, R.9
Birner, P.10
-
26
-
-
33846688115
-
Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth
-
DOI 10.1158/0008-5472.CAN-06-3567
-
Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. P Laakkonen M Waltari T Holopainen T Takahashi B Pytowski P Steiner D Hicklin K Persaud JR Tonra L Witte, Cancer Res 2007 67 2 593 599 10.1158/0008-5472.CAN-06-3567 17234768 (Pubitemid 46192197)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 593-599
-
-
Laakkonen, P.1
Waltari, M.2
Holopainen, T.3
Takahashi, T.4
Pytowski, B.5
Steiner, P.6
Hicklin, D.7
Persaud, K.8
Tonra, J.R.9
Witte, L.10
Alitalo, K.11
-
27
-
-
27644450912
-
Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin
-
10.1158/1078-0432.CCR-04-2270. 16000592
-
Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin. K Lamszus MA Brockmann C Eckerich P Bohlen C May U Mangold R Fillbrandt M Westphal, Clin Cancer Res 2005 11 13 4934 4940 10.1158/1078-0432.CCR-04-2270 16000592
-
(2005)
Clin Cancer Res
, vol.11
, Issue.13
, pp. 4934-4940
-
-
Lamszus, K.1
Brockmann, M.A.2
Eckerich, C.3
Bohlen, P.4
May, C.5
Mangold, U.6
Fillbrandt, R.7
Westphal, M.8
-
28
-
-
62549147841
-
Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: Relevance of receptor endocytosis
-
10.1073/pnas.0812059106. 19218427
-
Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: relevance of receptor endocytosis. T Ben-Kasus B Schechter S Lavi Y Yarden M Sela, Proc Natl Acad Sci USA 2009 106 9 3294 3299 10.1073/pnas.0812059106 19218427
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.9
, pp. 3294-3299
-
-
Ben-Kasus, T.1
Schechter, B.2
Lavi, S.3
Yarden, Y.4
Sela, M.5
-
29
-
-
13844306484
-
Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: Implications for cancer immunotherapy
-
10.1073/pnas.0409610102. 15684082
-
Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy. LM Friedman A Rinon B Schechter L Lyass S Lavi SS Bacus M Sela Y Yarden, Proc Natl Acad Sci USA 2005 102 6 1915 1920 10.1073/pnas.0409610102 15684082
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.6
, pp. 1915-1920
-
-
Friedman, L.M.1
Rinon, A.2
Schechter, B.3
Lyass, L.4
Lavi, S.5
Bacus, S.S.6
Sela, M.7
Yarden, Y.8
|