메뉴 건너뛰기




Volumn 14, Issue 3, 2010, Pages 248-255

Sirolimus-based calcineurin inhibitor withdrawal immunosuppressive regimen in kidney transplantation: A single center experience

Author keywords

Conversion; Immunosuppression; Sirolimus

Indexed keywords

ANTIBIOTIC AGENT; AZATHIOPRINE; BASILIXIMAB; CREATININE; CYCLOSPORIN A; GLUCOSE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; PREDNISONE; RAPAMYCIN; TACROLIMUS; VALACICLOVIR; VALGANCICLOVIR; CALCINEURIN; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

EID: 77956645435     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-010-0269-0     Document Type: Article
Times cited : (3)

References (40)
  • 1
    • 33645694582 scopus 로고    scopus 로고
    • Immunosuppression: Evolution in practice and trends
    • 1994-2004
    • Meier-Kriesche HU, Li S, Gruessner RW, et al. Immunosuppression: evolution in practice and trends, 1994-2004. Am J Transplant. 2006;6(5):1111-1131
    • (2006) Am J Transplant. , vol.6 , Issue.5 , pp. 1111-1131
    • Meier-Kriesche, H.U.1    Li, S.2    Gruessner, R.W.3
  • 2
    • 0029857451 scopus 로고    scopus 로고
    • Cyclosporine nephropathy: Pathophysiology and clinical impact
    • Shihab FS. Cyclosporine nephropathy: pathophysiology and clinical impact. Semin Nephrol. 1996;16:536-547
    • (1996) Semin Nephrol. , vol.16 , pp. 536-547
    • Shihab, F.S.1
  • 3
    • 10844292763 scopus 로고    scopus 로고
    • Immunosuppressive drugs for kidney transplantation
    • Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med. 2004;351:2715-2729
    • (2004) N Engl J Med. , vol.351 , pp. 2715-2729
    • Halloran, P.F.1
  • 4
    • 0030845767 scopus 로고    scopus 로고
    • Cyclosporine nephrotoxicity following cardiac transplantation
    • Woolfson RG, Neild GH. Cyclosporine nephrotoxicity following cardiac transplantation. Nephrol Dial Transplant. 1997;12:2054-2056
    • (1997) Nephrol Dial Transplant. , vol.12 , pp. 2054-2056
    • Woolfson, R.G.1    Neild, G.H.2
  • 5
    • 0035011155 scopus 로고    scopus 로고
    • Influence of cyclosporine, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation
    • Morales JM, Andres A, Rengel M, Rodicio JL. Influence of cyclosporine, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. Nephrol Dial Transplant. 2001;16:121-129
    • (2001) Nephrol Dial Transplant. , vol.16 , pp. 121-129
    • Morales, J.M.1    Andres, A.2    Rengel, M.3    Rodicio, J.L.4
  • 6
    • 33748301936 scopus 로고    scopus 로고
    • Immunosuppressive treatment and progression of histologic lesions in kidney allografts
    • Morales JM. Immunosuppressive treatment and progression of histologic lesions in kidney allografts. Kidney Int. 2005;99:S124-30.
    • (2005) Kidney Int. , vol.99
    • Morales, J.M.1
  • 8
    • 0033774719 scopus 로고    scopus 로고
    • A meta-analysis of immunosuppression withdrawal trials in renal transplantation
    • Kasiske BL, Chakkera HA, Louis TA, Ma JZ. A meta-analysis of immunosuppression withdrawal trials in renal transplantation. J Am Soc Nephrol. 2000;11:1910-1917
    • (2000) J Am Soc Nephrol. , vol.11 , pp. 1910-1917
    • Kasiske, B.L.1    Chakkera, H.A.2    Louis, T.A.3    Ma, J.Z.4
  • 9
    • 0032533409 scopus 로고    scopus 로고
    • Long-term outcome of a prospective randomized trial of conversion from cyclosporine to azathioprine treatment one year after renal transplantation
    • MacPhee IA, Bradley JA, Briggs JD, et al. Long-term outcome of a prospective randomized trial of conversion from cyclosporine to azathioprine treatment one year after renal transplantation. Transplantation. 1998;66:1186-1192
    • (1998) Transplantation. , vol.66 , pp. 1186-1192
    • MacPhee, I.A.1    Bradley, J.A.2    Briggs, J.D.3
  • 10
    • 0032526102 scopus 로고    scopus 로고
    • Mycophenolate mofetil in renal transplant recipients with cyclosporine-associated nephrotoxicity: A preliminary report
    • Ducloux D, Fournier V, Bresson-Vautrin C, et al. Mycophenolate mofetil in renal transplant recipients with cyclosporine-associated nephrotoxicity: a preliminary report. Transplantation. 1998;65:1504-1506
    • (1998) Transplantation. , vol.65 , pp. 1504-1506
    • Ducloux, D.1    Fournier, V.2    Bresson-Vautrin, C.3
  • 11
    • 4644277373 scopus 로고    scopus 로고
    • Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function
    • Weir MR, Blahut S, Drachenburg C, et al. Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. Am J Nephrol. 2004;24:379-386
    • (2004) Am J Nephrol. , vol.24 , pp. 379-386
    • Weir, M.R.1    Blahut, S.2    Drachenburg, C.3
  • 12
    • 14544288351 scopus 로고    scopus 로고
    • Low-dose mycophenolate mofetil is an effective and safe treatment to permit phased reduction in calcineurin inhibitors in chronic allograft nephropathy
    • Afzali B, Shah S, Chowdhury P, O'Sullivan H, Taylor J, Goldsmith D. Low-dose mycophenolate mofetil is an effective and safe treatment to permit phased reduction in calcineurin inhibitors in chronic allograft nephropathy. Transplantation. 2005;79:304-309
    • (2005) Transplantation , vol.79 , pp. 304-309
    • Afzali, B.1    Shah, S.2    Chowdhury O'sullivan, P.H.3    Taylor, J.4    Goldsmith, D.5
  • 13
    • 18244427344 scopus 로고    scopus 로고
    • Sirolimus in association with mycophenolate mofetil induction for the prevention of acute graft rejection in renal allograft recipients
    • Kreis H, Cisterne JM, Land W. Sirolimus in association with mycophenolate mofetil induction for the prevention of acute graft rejection in renal allograft recipients. Transplantation. 2000;69:1252-1260
    • (2000) Transplantation , vol.69 , pp. 1252-1260
    • Kreis, H.1    Cisterne, J.M.2    Land, W.3
  • 14
    • 33644678828 scopus 로고    scopus 로고
    • Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation
    • Hamdy AF, El-Agroudy AE, Bakr MA, et al. Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation. Am J Transplant. 2005;5:2531-2538
    • (2005) Am J Transplant. , vol.5 , pp. 2531-2538
    • Hamdy, A.F.1    El-Agroudy, A.E.2    Ma, B.3
  • 15
    • 0035872742 scopus 로고    scopus 로고
    • Multicenter trial exploring calcineurin inhibitor avoidance in renal transplantation
    • Vincenti F, Ramos E, Brattstrom C. Multicenter trial exploring calcineurin inhibitor avoidance in renal transplantation Transplantation. 2001 71 1282-1289.
    • (2001) Transplantation. , vol.71 , pp. 1282-1289
    • Vincenti, F.1    Ramos, E.2    Brattstrom, C.3
  • 16
    • 0035884710 scopus 로고    scopus 로고
    • Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
    • Johnson RWG, Kreis H, Oberbauer R, Brattstrom C, Claesson K, Eris J. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation. 2001;72:777-786
    • (2001) Transplantation , vol.72 , pp. 777-786
    • Rwg, J.1    Kreis, H.2    Oberbauer, R.3    Brattstrom, C.4    Claesson, K.5    Eris, J.6
  • 17
    • 33847717932 scopus 로고    scopus 로고
    • Mycophenolate mofetil/ sirolimus compared to other common immunosuppressive regimens in kidney transplantation
    • Srinivas TR, Schold JD, Guerra G, et al. Mycophenolate mofetil/ sirolimus compared to other common immunosuppressive regimens in kidney transplantation. Am J Transplant. 2007;7:586-594
    • (2007) Am J Transplant. , vol.7 , pp. 586-594
    • Srinivas, T.R.1    Schold, J.D.2    Guerra, G.3
  • 18
    • 33750991068 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: A systematic review of the evidence
    • Mulay AV, Cockfield S, Stryker R, Fergusson D, Knoll GA. Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: a systematic review of the evidence. Transplantation. 2006;82:1153-1162
    • (2006) Transplantation. , vol.82 , pp. 1153-1162
    • Mulay, A.V.1    Cockfield, S.2    Stryker, R.3    Fergusson, D.4    Knoll, G.A.5
  • 19
    • 7044262185 scopus 로고    scopus 로고
    • Is sirolimus a safe alternative to reduce or eliminate calcineurin inhibitors in chronic allograft nephropathy in kidney transplantation?
    • Lai WJ, Chiang YJ, Chen Y, Chu SH. Is sirolimus a safe alternative to reduce or eliminate calcineurin inhibitors in chronic allograft nephropathy in kidney transplantation? Transplant Proc. 2004;36:2056-2057
    • (2004) Transplant Proc. , vol.36 , pp. 2056-2057
    • Lai, W.J.1    Chiang, Y.J.2    Chen, Y.3    Chu, S.H.4
  • 20
    • 13644265974 scopus 로고    scopus 로고
    • An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency
    • Ram Peddi V, Jensik S, Pescovitz M, et al. An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency. Clin Transplant. 2005;19:130-136
    • (2005) Clin Transplant. , vol.19 , pp. 130-136
    • Ram Peddi, V.1    Jensik, S.2    Pescovitz, M.3
  • 21
    • 54149120306 scopus 로고    scopus 로고
    • Conversion to sirolimus for chronic renal allograft dysfunction: Risk factors for graft loss and severe side effects
    • Abramowicz D, Hadaya K, Hazzan M, et al. Conversion to sirolimus for chronic renal allograft dysfunction: risk factors for graft loss and severe side effects. Nephrol Dial Transplant. 2008;23:3727-3729
    • (2008) Nephrol Dial Transplant. , vol.23 , pp. 3727-3729
    • Abramowicz, D.1    Hadaya, K.2    Hazzan, M.3
  • 23
    • 33645945017 scopus 로고    scopus 로고
    • Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients
    • Stallone G, Infante B, Schena A, et al. Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients. J Am Soc Nephrol. 2005;16:3755-3763
    • (2005) J Am Soc Nephrol. , vol.16 , pp. 3755-3763
    • Stallone, G.1    Infante, B.2    Schena, A.3
  • 24
    • 33644694497 scopus 로고    scopus 로고
    • A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation
    • Watson CJ, Firth J, Williams PF, et al. A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation. Am J Transplant. 2005;5:2496-2502
    • (2005) Am J Transplant. , vol.5 , pp. 2496-2502
    • Watson, C.J.1    Firth, J.2    Williams, P.F.3
  • 25
    • 10844266734 scopus 로고    scopus 로고
    • Transplantation 50 years later: Progress, challenges, and promises
    • Sayegh MH, Carpenter CB. Transplantation 50 years later: progress, challenges, and promises N Engl J Med. 2004 351 2761-2766
    • (2004) N Engl J Med. , vol.351 , pp. 2761-2766
    • Sayegh, M.H.1    Carpenter, C.B.2
  • 26
    • 1442338509 scopus 로고    scopus 로고
    • Lack of improvement in renal allograft survival despite marked decrease in acute rejection rates over the most recent era
    • Meier-Kriesche HU, Schold DJ, Srinvas TR, Kaplan B. Lack of improvement in renal allograft survival despite marked decrease in acute rejection rates over the most recent era. Am J Transplant. 2004;4:378-383
    • (2004) Am J Transplant. , vol.4 , pp. 378-383
    • Meier-Kriesche, H.U.1    Schold, D.J.2    Srinvas, T.R.3    Kaplan, B.4
  • 29
    • 0025476721 scopus 로고
    • Cellular and molecular mechanisms of cyclosporine nephrotoxicity
    • Kopp JB, Klotman PE. Cellular and molecular mechanisms of cyclosporine nephrotoxicity. J Am Soc Nephrol. 1990;1:162-179
    • (1990) J Am Soc Nephrol. , vol.1 , pp. 162-179
    • Kopp, J.B.1    Klotman, P.E.2
  • 30
    • 22844450094 scopus 로고    scopus 로고
    • Renal dysfunction is a strong and independent risk factor of mortality and cardiovascular complications in renal transplantation
    • The ALERT study Group, et al.
    • Fellstorm B, Jardine AG, Soveri I, the ALERT study Group, et al. Renal dysfunction is a strong and independent risk factor of mortality and cardiovascular complications in renal transplantation. Am J Transplant. 2005;5:1986-1991
    • (2005) Am J Transplant. , vol.5 , pp. 1986-1991
    • Fellstorm, B.1    Jardine, A.G.2    Soveri, I.3
  • 31
    • 33747480956 scopus 로고    scopus 로고
    • Calcineurin inhibitor avoidance with declizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients
    • Asberg A, Midtvedit K, Line PD, et al. Calcineurin inhibitor avoidance with declizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients. Transplantation. 2006;82:62-68
    • (2006) Transplantation. , vol.82 , pp. 62-68
    • Asberg, A.1    Midtvedit, K.2    Line, P.D.3
  • 32
    • 0037184818 scopus 로고    scopus 로고
    • Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: A randomized, controlled study
    • Abramowicz D, Manas D, Lao M, Cyclosporine Withdrawal Study Group, et al. Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: a randomized, controlled study. Transplantation. 2002;74:1725-1734
    • (2002) Transplantation. , vol.74 , pp. 1725-1734
    • Abramowicz, D.1    Manas, D.2    Lao, M.3
  • 33
    • 27744527131 scopus 로고    scopus 로고
    • Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: Results of a five-year, prospective, randomized study
    • Cyclosporine Withdrawal Study Group, et al.
    • Abramowicz D, Del Carmen Rial M, Vitko S, Cyclosporine Withdrawal Study Group, et al. Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: results of a five-year, prospective, randomized study. J Am Soc Nephrol. 2005;16:2234-2240
    • (2005) J Am Soc Nephrol. , vol.16 , pp. 2234-2240
    • Abramowicz, D.1    Del Carmen Rial, M.2    Vitko, S.3
  • 34
    • 21644457432 scopus 로고    scopus 로고
    • Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation
    • Rapamune Maintenance Regimen Study Group, et al.
    • Oberbauer R, Segoloni G, Campistol JM, Rapamune Maintenance Regimen Study Group, et al. Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation. Transpl Int. 2005;18:22-28
    • (2005) Transpl Int. , vol.18 , pp. 22-28
    • Oberbauer, R.1    Segoloni, G.2    Campistol, J.M.3
  • 35
    • 2942534405 scopus 로고    scopus 로고
    • Sirolimus-based therapy after early cyclosporine withdrawal results in significantly better renal histology and function at 3 years fallowing kidney transplantation
    • Mota A, Taskinen EI, Paavonen T, Rapamune Maintenance Trial, et al. Sirolimus-based therapy after early cyclosporine withdrawal results in significantly better renal histology and function at 3 years fallowing kidney transplantation. Am J Transplant. 2004;4(6):953-961
    • (2004) Am J Transplant. , vol.4 , Issue.6 , pp. 953-961
    • Mota, A.1    Taskinen, E.I.2    Paavonen, T.3    Maintenance Trial, R.4
  • 36
    • 34548575285 scopus 로고    scopus 로고
    • Spare-the- Nephron (STN) one-year interim efficacy and safety of mycophenolate mofetil/sirolimus maintenance therapy after calcineurin inhibitor withdrawal in renal transplants
    • Pearson T, Wali R, Shidban H, Patel A, Chan L. Spare-the- Nephron (STN): one-year interim efficacy and safety of mycophenolate mofetil/sirolimus maintenance therapy after calcineurin inhibitor withdrawal in renal transplants. Am J Transplant. 2006;6(Suppl 2):432-439
    • (2006) Am J Transplant. , vol.6 , Issue.SUPPL 2 , pp. 432-439
    • Pearson, T.1    Wali, R.2    Shidban, H.3    Patel, A.4    Chan, L.5
  • 37
    • 65249134974 scopus 로고    scopus 로고
    • Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: Concept Study
    • Lebranchu Y, Thierry A, Toupannce O, et al. Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: Concept Study. Am J Transplant. 2009;9(5):1115-1123
    • (2009) Am J Transplant. , vol.9 , Issue.5 , pp. 1115-1123
    • Lebranchu, Y.1    Thierry, A.2    Toupannce, O.3
  • 38
    • 10744221884 scopus 로고    scopus 로고
    • Long-term benefits with sirolimusbased therapy after early cyclosporine withdrawal
    • For the Rapamune Maintenance Regimen Trial, et al.
    • Kreis H, Obernauer R, Campistol JM, For the Rapamune Maintenance Regimen Trial, et al. Long-term benefits with sirolimusbased therapy after early cyclosporine withdrawal. J Am Soc Nephrol. 2004;15:809-817
    • (2004) J Am Soc Nephrol. , vol.15 , pp. 809-817
    • Kreis, H.1    Obernauer, R.2    Campistol, J.M.3
  • 39
    • 34548302081 scopus 로고    scopus 로고
    • Early experience with conversion to sirolimus in a pediatric renal transplant population
    • Powell HR, Kara T, Jones CL. Early experience with conversion to sirolimus in a pediatric renal transplant population Pediatr Nephrol. 2007 22 1773-1777
    • (2007) Pediatr Nephrol. , vol.22 , pp. 1773-1777
    • Powell, H.R.1    Kara, T.2    Jones, C.L.3
  • 40
    • 37049017772 scopus 로고    scopus 로고
    • Posttransplantation conversion to sirolimus-based immunosuppression: A single center experience
    • Saber LT, Ikeda MY, Almeida JM. Posttransplantation conversion to sirolimus-based immunosuppression: a single center experience. Transplant Proc. 2007;39:3098-3100
    • (2007) Transplant Proc. , vol.39 , pp. 3098-3100
    • Saber, L.T.1    Ikeda, M.Y.2    Almeida, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.