The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA

International Journal of Cardiology

Volumn 143, Issue 3, 2010, Pages 264-270

  Goette, Andreas ^a   Wolfram, Oliver ^a   Jentsch Ullrich, Kathleen ^a   Martens Lobenhoffer, Jens ^a   Scalera, Fortunato ^a   Lendeckel, Uwe ^b   Bode Böger, Stefanie M ^a  

^a UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

ADMA; G CSF; Myeloperoxidase; Oxidative stress; Vascular biology

Indexed keywords

6 N,N' DIMETHYLARGININE; 8 ISOPROSTAGLANDIN F2 ALPHA; CD34 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GRANULOCYTE COLONY STIMULATING FACTOR; MYELOPEROXIDASE; N(G),N(G) DIMETHYLARGININE; NITRATE; NITRITE; STEM CELL FACTOR RECEPTOR; TROLOX C;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; LEUKOCYTE COUNT; LEUKOCYTOSIS; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSTAGLANDIN URINE LEVEL; PROTEIN EXPRESSION; STEM CELL MOBILIZATION;

AGED; AGED, 80 AND OVER; ANGINA PECTORIS; ANTIOXIDANTS; ARGININE; CELLS, CULTURED; CHROMANS; CORONARY DISEASE; ENDOTHELIAL CELLS; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKOCYTOSIS; MALE; MIDDLE AGED; OXIDATIVE STRESS; PEROXIDASE; UMBILICAL VEINS;

EID: 77956618049     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2009.02.020     Document Type: Article

References (36)

1. B. Assmus, V. Schächinger, and C. Teupe Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI) Circulation 106 2002 3009 3017
2. S. Janssens, C. Dubois, and J. Bogaert Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial Lancet. 367 2006 113 121
3. H. Ince, M. Petzsch, and H.D. Kleine Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI) Circulation 112 2005 3097 3106
4. H.J. Kang, H.S. Kim, and S.Y. Zhang Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial Lancet 363 2004 751 756
5. P. Menasché, A.A. Hagège, and J.T. Vilquin Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction J Am Coll Cardiol 41 2003 1078 1083
6. M.G. Chang, L. Tung, and R.B. Sekar Proarrhythmic potential of mesenchymal stem cell transplantation revealed in in vitro coculture model Circulation 113 2006 1832 1841
7. A.A. Kocher, M.D. Schuster, and M.J. Szabolcs Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function Nature Medicine 7 2001 430 436
8. J.C. Kovacic, D.W.M. Muller, and R.M. Graham Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease J Mol Cell Cardiol 42 2007 19 33
9. C. Sesti, S.L. Hale, C. Lutzko, and R.A. Kloner Granulocyte colony stimulating factor and stem cell factor improve contractile reserve of the infracted left ventricle independent of restoring muscle mass J Am Coll Cardiol 46 2005 1662 1669
10. K. Ueda, H. Takano, and H. Hasegawa Granulocyte colony stimulating factor directly inhibits myocardial ischemia-reperfusion injury through Akt-endothelial NO synthase pathway Arterioscler Thromb Vasc Biol 26 2006 e108 e113
11. J. Kastrup, R.S. Ripa, Y. Wang, and E. Jorgensen Myocardial regeneration induced by granulocyte-colony-stimulating factor mobilization of stem cells in patients with acute or chronic ischemic heart disease: a non-invasive alternative for clinical stem cell therapy? Eur Heart J 27 2006 2748 2754
12. D. Zohlnhofer, I. Ott, and J. Mehilli Stem cell mobilization by granulocyte-colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial JAMA 295 2006 1003 1010
13. M.G. Engelmann, H.D. Theiss, and C. Hennig-Theiss Autologous bone marrow stem cell mobilization induced by granulocyte-colony-stimulating factor after subacute ST-segment elevation myocardial infarction undergoing late revascularisation: final results from the G-CSF-STEMI trial J Am Coll Cardiol 48 2006 1712 1721
14. R.S. Ripa, Y. Wang, E. Jorgensen, H.E. Johnsen, B. Hesse, and J. Kastrup Intramyocardial injection of vascular derived endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischemic heart disease Eur Heart 27 2006 1785 1792
15. R.H. Böger, S.M. Bode-Böger, and A. Szuba Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia Circulation 98 18 Nov 3 1998 1842 1847
16. F. Scalera, J. Borlak, and B. Beckmann Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence Arterioscler Thromb Vasc Biol. 24 10 2004 Oct 1816 1822
17. J.T. Kielstein, B. Impraim, and S. Simmel Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans Circulation. 109 2 2004 Jan 20 172 177 (Pubitemid 38114135)
18. T. Thum, D. Tsikas, and S. Stein Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine J Am Coll Cardiol. 46 9 2005 1693 1701
19. A. Goette, K. Jentsch-Ullrich, and U. Lendeckel Effect of atrial fibrillation on hematopoietic progenitor cells: a novel pathophysiologic role of the atrial natriuretic peptide? Circulation 108 2003 2446 2449
20. J. Martens-Lobenhoffer, and S.M. Bode-Böger Fast and efficient determination of arginine, symmetric dimethylarginine, and asymmetric dimethylarginine in biological fluids by hydrophilic interaction liquid chromatography-electrospray tandem mass spectrometry Clin Chem 52 2006 488 493
21. D. Tsikas, R.H. Böger, S.M. Bode-Böger, F.M. Gutzki, and J.C. Frölich Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography-mass spectrometry using their 15N-labelled analogs J Chromatogr. B 661 1994 185 191
22. K.C. Bohnstedt, B. Karlberg, L.O. Wahlund, M.E. Johnhagen, H. Basun, and S. Schmidt Determination of isoprostanes in urine samples from Alzheimer patients using porous graphitic carbon liquid chromatography-tandem mass spectrometry J Chromatogr. B 796 2003 11 19
23. F. Scalera, J.T. Kielstein, J. Martens-Lobenhoffer, S.C. Postel, M. Täger, and S.M. Bode-Böger Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase J Am Soc Nephrol 16 2005 892 898
24. J.P. Eiserich, S. Baldus, and M.L. Brennan Myeloperoxidase, a leukocyte-derived vascular NO oxidase Science 296 2003 2391 2394
25. S. Lehrke, R. Mazhari, D.J. Durand, M. Zheng, D. Bedja, and J.M. Zimmet Aging impairs the beneficial effect of granulocyte colony stimulating factor and stem cell factor on post-myocardial infarction remodeling Circ Res 99 2006 553 560
26. S.J. Nicholls, and S.L. Hazen Myeloperoxidase and cardivascular disease Arterioscler Thromb Vasc Biol 25 2005 1102 1111
27. C. Zhang, R. Patel, and J.P. Eiserich Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid Am J Physiol Heart Circ Physiol 81 2001 H1469 H1475
28. F. Auchere, and C. Capeillere-Blandin NADPH as a co-substrate for studies of the chlorinating activity of myeloperoxidase Biochem J. 343 Pt 3 1999 603 613
29. S. Sugiyama, K. Kugiyama, M. Aikawa, S. Nakamura, H. Ogawa, and P. Libby Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis Arterioscler Thromb Vasc Biol. 24 2004 1309 1314
30. S. Sugiyama, Y. Okada, G.K. Sukhova, R. Virmani, J.W. Heinecke, and P. Libby Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes Am J Pathol. 158 2001 879 891
31. M.G. Engelmann, H.D. Theiss, and C. Hennig-Theiss Autologous bone marrow stem cell mobilization induced by granulocyte colony-stimulating factor after subacute ST-segment elevation myocardial infarction undergoing late revascularization: final results from the G-CSF-STEMI trial JACC. 48 2006 1712 1721
32. O. Wolfram, K. Jentsch-Ullrich, and A. Wagner G-CSF-induced mobilization of CD34 progenitor cells and proarrhythmic effects in patients with severe coronary artery disease Pacing Clin Electrophysiol. 30 Suppl 1 2007 S166 S169
33. D. Zohlnhöfer, A. Dibra, and T. Koppara Stem cell mobilization by granulocyte colony-stimulating factor for myocardial recovery after acute myocardial infarction: a meta-analysis J Am Coll Cardiol. 51 2008 1429 1437
34. K.W. Park, Y.W. Kwon, and H.J. Cho G-CSF exerts dual effects on endothelial cells-opposing actions of direct eNOS induction versus indirect CRP elevation J Mol Cell Cardiol. 45 2008 670 678
35. J. Yang, Y. Cheng, R. Ji, and C. Zhang Novel model of inflammatory neointima formation reveals a potential role of myeloperoxidase in neointimal hyperplasia Am J Physiol Heart Circ Physiol. 291 2006 H3087 H3093
36. A.J. Coats Ethical authorship and publishing Int J Cardiol 131 2009 149 150