Influence of glutathione-S-transferase theta (GSTT1) and mu (GSTM1) gene polymorphisms on the susceptibility of hepatocellular carcinoma in Taiwan

Journal of Surgical Oncology

Volumn 102, Issue 4, 2010, Pages 301-307

  Kao, Chia Chun ^a   Chen, M U Kuan ^a,b,c   Kuo, W U Hsien ^d,e   Chen, Tzy Yen ^a,f   Su, Shih Chi ^g   Hsieh, Y I Hsien ^a   Liu, Chuen Lan ^a   Chou, Ming Chih ^a   Tsai, Hsiu Ting ^a   Yang, Shun F A ^a,f  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c MINGDAO UNIVERSITY   (Taiwan)

^d TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^e CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^f CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Glutathione S transferases; Hepatocellular carcinoma; Single nucleotide polymorphism

Indexed keywords

GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1;

ADULT; AGE DISTRIBUTION; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; NULL ALLELE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TAIWAN;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, GENETIC; TAIWAN;

EID: 77956596975     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21643     Document Type: Article

References (54)

1. Jakoby WB: The glutathione S-transferases: A group of multifunctional detoxification proteins. Adv Enzymol Relat Areas Mol Biol 1978;46:383-414.
2. Chasseaud LF: The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res 1979;29:175-274.
3. Rebbeck TR: Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol Biomarkers Prev 1997;6:733-743.
4. Hoensch H, Morgenstern I, Petereit G, et al.: Influence of clinical factors, diet, and drugs on the human upper gastrointestinal glutathione system. Gut 2002;50:235-240.
5. de Bruin WC, Wagenmans MJ, Peters WH: Expression of glutathione S-transferase alpha, P 1-1 and T 1-1 in the human gastrointestinal tract. Jpn J Cancer Res 2000;91:310-316.
6. Knight TR, Choudhuri S, Klaassen CD: Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice. Toxicol Sci 2007;100:513-524.
7. Mulder TP, Manni JJ, Roelofs HM, et al.: Glutathione S-transferases and glutathione in human head and neck cancer. Carcinogenesis 1995;16:619-624.
8. Bosch FX, Ribes J, Cleries R, et al.: Epidemiology of hepatocellular carcinoma. Clin Liver Dis 2005;9:191-211.
9. Parkin DM, Bray F, Ferlay J, et al.: Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
10. Hsiao PC, Chen MK, Su SC, et al.: Hypoxia inducible factor-1α gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinoma. J Surg Oncol 2010; DOI 10.1002/jso.21539.
11. Yamazaki Y, Kakizaki S, Sohara N, et al.: Hepatocellular carcinoma in young adults: The clinical characteristics, prognosis, and findings of a patient survival analysis. Dig Dis Sci 2007;52:1103-1107. (Pubitemid 46481273)
12. Shariff MI, Cox IJ, Gomaa AI, et al.: Hepatocellular carcinoma: Current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics. Expert Rev Gastroenterol Hepatol 2009;3:353-367.
13. Leao-Filho GC, Lopes EP, Ferraz AA, et al.: Hepatitis G virus infection in patients with hepatocellular carcinoma in Recife, Brazil. Jpn J Clin Oncol 2007;37:632-636.
14. Chang CC, Chen SC, Hsieh YH, et al.: Stromal cell-derived factor-1 but not its receptor, CXCR4, gene variants increase susceptibility and pathological development of hepatocellular carcinoma. Clin Chem Lab Med 2009;47:412-448.
15. Chen SY, Wang LY, Lunn RM, et al.: Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls. Int J Cancer 2002;99:14-21.
16. Chen CJ, Yu MW, Liaw YF: Epidemiological characteristics and risk factors of hepatocellular carcinoma. J Gastroenterol Hepatol 1997;12:S294-S308.
17. Ladero JM, Martinez C, Garcia-Martin E, et al.: Glutathione S-transferase M1 and T1 genetic polymorphisms are not related to the risk of hepatocellular carcinoma: A study in the Spanish population. Eur J Cancer 2006;42:73-77.
18. Davies MH, Elias E, Acharya S, et al.: GSTM1 null polymorphism at the glutathione S-transferase M1 locus: Phenotype and genotype studies in patients with primary biliary cirrhosis. Gut 1993;34:549-553.
19. Chang TW, Wang SM, Guo YL, et al.: Glutathione S-transferase polymorphisms associated with risk of breast cancer in southern Taiwan. Breast 2006;15:754-761.
20. Ebert MN, Klinder A, Peters WH, et al.: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. Carcinogenesis 2003;24:1637-1644.
21. Lampe JW: Diet, genetic polymorphisms, detoxification, and health risks. Altern Ther Health Med 2007;13:S108-S111.
22. Elexpuru-Camiruaga J, Buxton N, Kandula V, et al.: Susceptibility to astrocytoma and meningioma: Influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci. Cancer Res 1995;55:4237-4239.
23. Wu FY, Wu HD, Yang HL, et al.: Associations among genetic susceptibility, DNA damage, and pregnancy outcomes of expectant mothers exposed to environmental tobacco smoke. Sci Total Environ 2007;386:124-133.
24. Mohammadzadeh Ghobadloo S, Yaghmaei B, Allameh A, et al.: Polymorphisms of glutathione S-transferase M1, T1, and P1 in patients with HBV-related liver cirrhosis, chronic hepatitis, and normal carriers. Clin Biochem 2006;39:46-49.
25. Khan AJ, Choudhuri G, Husain Q, et al.: Polymorphism in glutathione-S-transferases: A risk factor in alcoholic liver cirrhosis. Drug Alcohol Depend 2009;101:183-190.
26. Huang YS, Su WJ, Huang YH, et al.: Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H: Quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury. J Hepatol 2007;47:128-134.
27. Ueda K, Ishitsu T, Seo T, et al.: Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity. Pharmacogenomics 2007;8:435-442.
28. Fukushima Y, Seo T, Hashimoto N, et al.: Glutathione-S-transferase (GST) M1 null genotype and combined GSTM1 and GSTT1 null genotypes are risk factors for increased serum gamma-glutamyltransferase in valproic acid-treated patients. Clin Chim Acta 2008;389:98-102.
29. Lucena MI, Andrade RJ, Martinez C, et al.: Glutathione Stransferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology 2008;48: 588-596.
30. Perera FP: Environment and cancer: Who are susceptible? Science 1997;278:1068-1073.
31. Yu MW, Gladek-Yarborough A, Chiamprasert S, et al.: Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma. Gastroenterology 1995;109:1266-1273.
32. Yeh CB, Tsai HT, Chen YC, et al.: Genetic polymorphism of CCR2-64I increased the susceptibility of hepatocellular carcinoma. J Surg Oncol 2010; DOI 10.1002/jso.21623.
33. Poulsen HELS, Wassermann K: Cancer risk related to genetic polymorphisms in carcinogen metabolism and DNA repair. Pharmacol Toxicol 1993;72:93-103.
34. Dong LM, Potter JD, White E, et al.: Genetic susceptibility to cancer: The role of polymorphisms in candidate genes. JAMA 2008;299:2423-2436.
35. Ye Z, Song H: Glutathione S-transferase polymorphisms (GSTM1, GSTP1 and GSTT1) and the risk of acute leukaemia: A systematic review and meta-analysis. Eur J Cancer 2005;41:980-989.
36. de Jong MM, Nolte IM, te Meerman GJ, et al.: Low penetrance genes and their involvement in colorectal cancer susceptibility. Cancer Epidemiol Biomarkers Prev 2002;11:1332-1352.
37. Chen MK, Tsai HT, Chung TT, et al.: Glutathione S-transferase P1 and alpha gene variants; role in susceptibility and tumor size development of oral cancer. Head Neck 2010; DOI 10.1002/hed.21297.
38. White DL, Li D, Nurgalieva Z, et al.: Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: A HuGE systematic review and meta-analysis. Am J Epidemiol 2008;167:377-389.
39. Kiran M, Chawla YK, Kaur J: Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India. DNA Cell Biol 2008;27:687-694.
40. Tremblay S, Pintor Dos Reis P, Bradley G, et al.: Young patients with oral squamous cell carcinoma: Study of the involvement of GSTP1 and deregulation of the Fanconi anemia genes. Arch Otolaryngol Head Neck Surg 2006;132:958-966.
41. Kwabi-Addo B, Chung W, Shen L, et al.: Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res 2007;13:3796-3802.
42. Nishida N, Nagasaka T, Nishimura T, et al.: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology 2008;47:908-918.
43. Miki D, Aikata H, Uka K, et al.: Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma. J Gastroenterol 2008;43:550-557.
44. Fuke H, Sugimoto K, Shiraki K, et al.: Predictive factors for distant recurrence of HCV-related hepatocellular carcinoma after radiofrequency ablation combined with chemoembolization. Aliment Pharmacol Ther 2008;27:1253-1260.
45. Changchien CS, Chen CL, Yen YH, et al.: Analysis of 6381 hepatocellular carcinoma patients in southern Taiwan: Prognostic features, treatment outcome, and survival. J Gastroenterol 2008;43:159-170.
46. Kumar M, Kumar R, Hissar SS, et al.: Risk factors analysis for hepatocellular carcinoma in patients with and without cirrhosis: A case-control study of 213 hepatocellular carcinoma patients from India. J Gastroenterol Hepatol 2007;22:1104-1111.
47. Yano Y, Yamashita F, Kuwaki K, et al.: Clinical features of hepatitis C virus-related hepatocellular carcinoma and their association with alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II. Liver Int 2006;26:789-795.
48. Zhou L, Rui JA, Wang SB, et al.: Clinicopathological features, post-surgical survival and prognostic indicators of elderly patients with hepatocellular carcinoma. Eur J Surg Oncol 2006;32:767-772.
49. Firpi RJ, Nelson DR: Viral hepatitis: Manifestations and management strategy. Hematology Am Soc Hematol Educ Program 2006;75:380.
50. Chen CJ, Yu MW, Liaw YF, et al.: Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma. Am J Hum Genet 1996;59:128-134.
51. Sun CA, Wang LY, Chen CJ, et al.: Genetic polymorphisms of glutathione S-transferases M1 and T1 associated with susceptibility to aflatoxin-related hepatocarcinogenesis among chronic hepatitis B carriers: A nested case-control study in Taiwan. Carcinogenesis 2001;22:1289-1294.
52. Watanabe I, Tomita A, Shimizu M, et al.: A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. Clin Pharmacol Ther 2003;73:435-455.
53. Kandemir O, Tamer L, Tasdelen B: Effects of GSTT1, GSTM1 and GSTP1 gene polymorphism on the course of hepatitis B virus infection. Hepatogastroenterology 2008;55:1729-1733.
54. Synopsis for Table of Contents.