RNAi-mediated downregulation of uPAR synergizes with targeting of HER2 through the ERK pathway in breast cancer cells

International Journal of Cancer

Volumn 127, Issue 7, 2010, Pages 1507-1516

  Li, Changfei ^a   Cao, Sheng ^a   Liu, Zhen ^a   Ye, Xin ^a   Chen, Lizhao ^a   Meng, Songdong ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Breast cancer; ERK; HER2; RNAi; UPAR

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; SYNAPTOPHYSIN; TRASTUZUMAB; UROKINASE RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; HER2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; BREAST TUMOR; CELL CYCLE; CELL DIVISION; DRUG EFFECT; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PLASMID; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DOWN-REGULATION; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HUMANS; PLASMIDS; RECEPTOR, ERBB-2; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; RNA INTERFERENCE; SINCALIDE; TRANSFECTION;

EID: 77956594900     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25159     Document Type: Article

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