The role of corticosteroids and stress in chronic pain conditions

Metabolism: Clinical and Experimental

Volumn 59, Issue SUPPL. 1, 2010, Pages

  McEwen, Bruce S ^a   Kalia, Madhu ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CORTICOTROPIN RELEASING FACTOR RECEPTOR; HYDROCORTISONE; LOCAL ANESTHETIC AGENT; GLUCOCORTICOID RECEPTOR;

ANALGESIA; BURNOUT; CHRONIC FATIGUE SYNDROME; CHRONIC PAIN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; FIBROMYALGIA; HUMAN; HYPERALGESIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IRRITABLE COLON; PAIN THRESHOLD; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; STRESS; ADAPTATION; CHRONIC DISEASE; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MENTAL STRESS; PAIN; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SPINAL CORD;

ADAPTATION, PHYSIOLOGICAL; ADRENAL CORTEX HORMONES; ANALGESIA; CHRONIC DISEASE; HUMANS; HYPERALGESIA; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; PAIN; PAIN THRESHOLD; PITUITARY-ADRENAL SYSTEM; RECEPTORS, GLUCOCORTICOID; SPINAL CORD; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL;

EID: 77956582773     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2010.07.012     Document Type: Review

References (67)

1. Maloney E.M., Gurbaxani B.M., and Jones J.F. Chronic fatigue syndrome and high allostatic load Pharmacogenomoics 7 2006 467 473
2. Maloney E.M., Boneva R., and Nater U.M. Chronic fatigue syndrome and high allostatic load: results from a population-based case control study in Georgia Psychosom Med 71 2009 549 556
3. Benedettii F., Mayberg H.S., and Wager T.D. Neurobiological mechanism of the placebo effect J Neurosci 25 2005 10390 10402
4. Eippert F., Bingel U., and Schoell E.D. Activation of the opioidergic descending pain control system underlies placebo analgesia Neuron 63 2009 533 543
5. Eippert F., Finsterbusch J., and Bingel U. Science 326 2009 404
6. Harris R.E., Sundgren P.C., and Pang Y. Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia Arthritis Rheum 58 2008 903 907
7. Harris R.E., Sundgren P.C., and Craig A.D. Elevated insular glutamate in fibromyalgia is associated wit experimental pain Arthritis and Rheumatism 60 2009 3146 3152
8. Katzung B.G., Masters S.B., and Trevor A.L. Adrenocorticosteroids. Chapter 39 Basic and clinical pharmacology 11th ed 2009 McGraw-Hill Companies
9. Millan M.J. The induction of pain: an integrative review Prog Neurobiol 57 1999 1 164
10. Gamaro G.D., XCavier M.H., and Denardin J.D. The effects of acute and repeated restraint stress on the nociceptive response in rats Physiol Behav 63 1998 693 697
11. Pinto-Ribeiro F, Moreira V, Pego JM, Leao P, Almeida A, Sousa N. Anti-nociception induced by chronic glucocorticoid treatment is correlated to local modulation of spinal neurotransmitter content. Molecular Pain 2009;5:41,1-11
12. Salerno A., and Hermann R. Efficacy and safety of steroid use for postoperative pain relief. Update and review of the medical literature J Bone Joint Surg 88 2006 1362 1371
13. Chrousos G., and Gold P. The concepts of stress and stress system disorders JAMA 267 1992 1224 1252
14. Crofford L.J. The hypothalamic-pituitary-adrenal axis in the pathogenesis of rheumatic diseases Endocrinol Metab Clin N Am 31 2002 1 13
15. Beck M. Stress so bad it hurts-really The Wall Street Journal 2009
16. Clark W.C., Yang J.C., and Janal M.N. Altered pain and visual sensitivity in human: the effects of acute and chronic stress Ann NY Acad Sci 467 1986 116 129
17. Imbe H., Iwai-Liao Y., and Senba E. Stress-induced hyperalgesia: animal models and putative mechanisms Front Biosci 11 2006 2179 2192
18. Dufton L.M., Konik B., and Colletti R. Effects of stress on pain threshold and tolerance in children with recurrent abdominal pain Pain 136 2008 38 43
19. Akil H., Mayer D.J., and Liebeskind J.C. Antagonism of stimulation-produced analgesia by naloxone a narcotic antagonist Science 192 1976 961 962
20. Rubinstein M. Absence of opioid stress-induced analgesia in mice taking endorphin by site-directed mutagenesis Proc Natl Acad Sci U S A 93 1996 3995 4000
21. Terman G.W., Shavit Y., and Lewis J.W. Intrinsic mechanisms of pain inhibition: activation by stress Science 226 1984 1270 1277
22. Crofford L.J., and Demitrack M.A. Evidence that abnormalities of central neurohormonal systems are key to understanding fibromyalgia and chronic fatigue syndrome Rheum Dis Clin North Am 22 1996 267 284
23. Crofford L.J., Young E.A., and Cary Engleberg N. Basal circadian and pulsatile ACTH and cortisol secretion in patients with fibromyalgia and/or chronic fatigue syndrome Brain Behav Immun 18 2004 314 325
24. Lariviere W.R., and Melzack R. The role of corticotrophin-releasing factor in pain and analgesia Pain 84 2000 1 12
25. Fu Y., and Neugebauer V. Differential mechanisms of CRF1 and CRF 2 receptor functions in the amygdala in pain-related synaptic facilitation and behavior J Neurosci 28 2008 3861 3876
26. Ji G., and Neugebauer V. Differential effects of CRF1 and CRF2 receptor antagonists on pain-related sensitization of neurons in the central nucleus of the amygdala J Neurophysiol 97 2007 3893 3904
27. McEwen B.S., and Stellar E. Stress and the individual. Mechanisms leading to disease Arch Intern Med 153 1993 2093 2101
28. McEwen B.S. Protective and damaging effects of stress mediators: central role of the brain Dialogues Clin Neurosci 8 2006 367 381
29. McEwen B.S. Physiology and neurobiology of stress and adaptation: central role of the brain Physiol Rev 87 2007 873 904
30. MacLennan A.J., Drugan R.C., and Hyson R.L. Corticosterone: a critical factor in an opioid form of stress-induced analgesia Science 215 1982 530 1532
31. Wang S. Central glucocorticoid receptors regulate the upregulation of spinal cannabinoid-1 receptors after peripheral nerve injury in rats Pain 31 2007 96 105
32. Hohmann A.G. An endocannabinoid mechanism for stress-induced analgesia Nature 435 2005 1108 1112
33. 1 receptor density in the hippocampus Hippocampus 18 2008 221 226
34. Tasker J.G., Di S., and Malcher-Lopes R. Minireview: rapid glucocorticoid signaling via membrane-associated receptors Endocrinology 147 2008 5549 5556
35. Rivat C. Non-nociceptive environmental stress induces hyperalgesia, not analgesia, in pain and opioid-experienced rats Neuropsychopharm 32 2008 2217 2228
36. Lawal A., Kern M., and Sidhu H. Novel evidence for hypersensitivity of visceral sensory neural circuitry in irritable bowel syndrome patients Gastroenterology 130 2006 26 33
37. Wang S., Lim G., Zeng Q., Sung B., Yang L., and Mao J. Central glucocorticoid receptors modulate the expression and function of spinal NMDA receptors after peripheral nerve injury J Neurosci 25 2005 488 495 (Pubitemid 40105620)
38. Takasaki I., Kurihara T., Saegusa H., Zong S., and Tanabe T. Effects of glucocorticoid receptor antagonists on allodynia and hyperalgesia in mouse model of neuropathic pain Eur J Pharmacol 524 2005 80 83
39. Wang S., Lim G., Yang L., Syng B., and Mao J. Downregulation of spinal glutamate transporter EAAC1 following nerve injury is regulated by central glucocorticoid receptors in rats Pain 120 2006 78 85
40. Kingery W.S. Glucocorticoid inhibition of neuropathic hyperalgesia and spinal Fos expression Anesth Analg 92 2001 476 482
41. Ikeda R., Takahashi Y., Inoue K., and Kato F. NMDA receptor-independent synaptic plasticity in central amygdala in rat model of neuropathic pain Pain 127 2007 161 172
42. Demitrack M.A. Neuroendocrine research strategies in chronic fatigue syndrome P.J. Goodnick, N.G. Klimas, Chronic fatigue and related immune deficiency syndromes 1996 American Psychiatric Press, Inc
43. Fries E., Hesse J., Hellhammer J., and Hellhammer D.H. A new view on hypocortisolism Psychoneuroendocrinology 30 2005 1010 1016
44. Mayer E.A. Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis Pain 115 2005 398 409
45. Garrosa E., Moreno-Jimenez B., Liang Y., and Gonzalez J.L. The relationship between socio-demographic variables, job stressors, burnout, and hardly personality in nurses: a exploratory study Int J Nursing Studies 2006
46. Huibers M.J.H. Fatigue, burnout, and chronic fatigue syndrome among employees on sick leave: do attributions make the difference? Occup Environ Med 60 2003 i26 i31
47. Pruessner J.C., Hellhammer D.H., and Kirschbaum C. Burnout, perceived stress, and cortisol responses to awakening Psychosom Med 61 1999 197 204
48. Crofford L.J. The hypothalamic-pituitary-adrenal axis in the pathogenesis of rheumatic diseases Endocrinol Metab Clin North Am 31 2002 1 13
49. Fukuda K. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group Ann Intern Med 121 1994 953 959
50. Sternberg E.M. Hyperimmune fatigue syndromes: diseases of the stress response? J Rheumatol 20 1993 418 421
51. Clauw D.J., and Chrousos G.P. Chronic pain and fatigue syndromes: overlapping clinical and neuroendocrine features and potential pathogenic mechanisms Neuroimmunomodulation 4 1997 134 153
52. Wolfe F. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee Arthritis Rheum 33 1990 160 172
53. Goertze B.N. Allostatic load is associated with symptoms in chronic fatigue syndrome patients Pharmacogenomics 7 2006 485 494
54. Cleare A.J. The neuroendocrinology of chronic fatigue syndrome Endocrine Rev 24 2003 236 252
55. Mommersteeg P.M.C., Heijnen C.J., Kavelaars A., and van Doornen L.J.P. Immune and endocrine function in burnout syndrome Psychosom Med 68 2006 879 886
56. Mommersteeg P.M.C., Heijnen C.J., Verbraak M.J.P.M., and van Doornen L.J.P. Clinical burnout is not reflected in the cortisol awakening response, the day-curve or the response to a low-dose dexamethasone suppression test Psychoneuroendocrinology 31 2006 216 225
57. Sonnentag S. Burnout and functioning of the hypothalamus-pituitary- adrenal axis-there are no simple answers Scand J Work Environ Health 32 2006 333 337
58. Melamed S., Shirom A., Toker S., and Shapira I. Burnout and risk of type 2 diabetes: a prospective study of apparently healthy employed persons Psychosom Med 68 2006 863 869
59. Diatchenko L., Nackley A.G., Slade G.D., Fillingim R.B., and Maixner W. Idiopathic pain disorders-pathways of vulnerability Pain 123 2006 226 230
60. Houdenhove B.V., and Luyten P. Beyond dualism: the role of life stress in chronic pain Pain 113 2005 238 247
61. Ribeiro S.C., Kennedy S.E., Smith Y.R., Stohler C.S., and Zubieta J.K. Interface of physical and emotional stress regulation through the endogenous opioid system and μ-opioid receptors Prog Neuropsychopharmacol Biol Psychiatry 29 2005 1264 1280
62. Naliboff B.D. Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel syndrome patients Gastroenterology 131 2006 352 365
63. Wood P.B. Fibromyalgia syndrome: a central role for the hippocampus-a theoretical construct J Musculoskeletal Pain 12 2004 19 26
64. Wood P.B. Mesolimbic dopaminergic mechanisms and pain control Pain 120 2006 230 234
65. McLean S.A. Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia Neuropsychopharm 31 2006 2776 2782
66. Wager T.D. Placebo-induced changes in fMRI in the anticipation and experience of pain Science 303 2004 1162 1167
67. Fields D.R. New culprits in chronic pain Sci Am 2009 50 57