A comprehensive model of the spectrin divalent tetramer binding region deduced using homology modeling and chemical cross-linking of a mini-spectrin

Journal of Biological Chemistry

Volumn 285, Issue 38, 2010, Pages 29535-29545

  Li, Donghai ^a,b   Harper, Sandra L ^a   Tang, Hsin Yao ^a   Maksimova, Yelena ^c   Gallagher, Patrick G ^c   Speicher, David W ^a  

^a WISTAR INSTITUTE   (United States)

^b NANJING UNIVERSITY   (China)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; COMPLEXATION; CROSSLINKING; CYTOLOGY; DYES;

C-TERMINAL TAIL; CHEMICAL CROSS-LINKING; COMPREHENSIVE MODEL; CONFORMATIONAL CHANGE; CRITICAL DISTANCE; HETEROGENEOUS STRUCTURES; HOMOLOGY MODELING; INTRAMOLECULAR CROSS-LINKS; MOLECULAR DISTANCES; N-TERMINALS; RESOLUTION STRUCTURE; ROPE-LIKE STRUCTURES; SPECTRIN; TETRAMER INTERCONVERSION; TETRAMERS; WILD TYPES;

CONFORMATIONS;

SPECTRIN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ANEMIA; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ESCHERICHIA COLI; GENE MUTATION; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; WILD TYPE; AMINO ACID SEQUENCE; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN MULTIMERIZATION; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; BINDING SITES; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTRIN; TANDEM MASS SPECTROMETRY;

EID: 77956540295     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.145573     Document Type: Article

References (36)

1. Marchesi, V. T., and Steers, E., Jr. (1968) Science 159, 203-204
2. Agre, P., Casella, J. F., Zinkham, W. H., McMillan, C., and Bennett, V. (1985) Nature 314, 380-383
3. Speicher, D. W., and Marchesi, V. T. (1984) Nature 311, 177-180
4. Ursitti, J. A., Kotula, L., DeSilva, T. M., Curtis, P. J., and Speicher, D. W. (1996) J. Biol. Chem. 271, 6636-6644
5. Speicher, D. W., Weglarz, L., and DeSilva, T. M. (1992) J. Biol. Chem. 267, 14775-14782
6. Li, D., Tang, H. Y., and Speicher, D. W. (2008) J. Biol. Chem. 283, 1553-1562
7. Li, D., Harper, S., and Speicher, D. W. (2007) Biochemistry 46, 10585-10594
8. Liu, S. C., Derick, L. H., and Palek, J. (1987) J. Cell Biol. 104, 527-536
9. Liu, S. C., Windisch, P., Kim, S., and Palek, J. (1984) Cell 37, 587-594
10. Morrow, J. S., and Marchesi, V. T. (1981) J. Cell Biol. 88, 463-468
11. Brenner, S. L., and Korn, E. D. (1980) J. Biol. Chem. 255, 1670-1676
12. Cohen, C. M., Tyler, J. M., and Branton, D. (1980) Cell 21, 875-883
13. Ungewickell, E., Bennett, P. M., Calvert, R., Ohanian, V., and Gratzer, W. B. (1979) Nature 280, 811-814
14. Fowler, V., and Taylor, D. L. (1980) J. Cell Biol. 85, 361-376
15. An, X., Lecomte, M. C., Chasis, J. A., Mohandas, N., and Gratzer, W. (2002) J. Biol. Chem. 277, 31796-31800
16. Zarkowsky, H. S., Mohandas, N., Speaker, C. B., and Shohet, S. B. (1975) Br. J. Haematol. 29, 537-543
17. Gallagher, P. G. (2004) Semin. Hematol. 41, 142-164
18. Gaetani, M., Mootien, S., Harper, S., Gallagher, P. G., and Speicher, D. W. (2008) Blood 111, 5712-5720
19. Ipsaro, J. J., Harper, S. L., Messick, T. E., Marmorstein, R., Mondragón, A., Speicher, D. W. (2010) Blood 115, 4843-4852
20. Harper, S. L., Li, D., Maksimova, Y., Gallagher, P. G., Speicher, D. W. (2010) J. Biol. Chem. 285, 11003-11012
21. Speicher, K. D., Kolbas, O., Harper, S., and Speicher, D. W. (2000) J. Biomol. Tech. 11, 74-86
22. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
23. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
24. DeLano, W. L. (2002) The PyMOL Molecular Graphics System, DeLano Scientific LLC, San Carlos, CA
25. Comeau, S. R., Gatchell, D. W., Vajda, S., and Camacho, C. J. (2004) Bioinformatics 20, 45-50
26. Jones, S., and Thornton, J. M. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 13-20
27. Laskowski, R. A., Moss, D. S., and Thornton, J. M. (1993) J. Mol. Biol. 231, 1049-1067
28. Mandell, J. G., Roberts, V. A., Pique, M. E., Kotlovyi, V., Mitchell, J. C., Nelson, E., Tsigelny, I., and Ten Eyck, L. F. (2001) Protein Eng. 14, 105-113
29. Chen, R., Li, L., and Weng, Z. (2003) Proteins 52, 80-87
30. Chen, R., Tong, W., Mintseris, J., Li, L., and Weng, Z. (2003) Proteins 52, 68-73
31. El-Shafey, A., Tolic, N., Young, M. M., Sale, K., Smith, R. D., and Kery, V. (2006) Protein Sci. 15, 429-440
32. Park, S., Caffrey, M. S., Johnson, M. E., and Fung, L. W. (2003) J. Biol. Chem. 278, 21837-21844
33. Park, S., Johnson, M. E., and Fung, L. W. (2000) FEBS Lett. 485, 81-86
34. Tang, H. Y., and Speicher, D. W. (2004) Biochemistry 43, 4251-4262
35. Manno, S., Takakuwa, Y., Nagao, K., and Mohandas, N. (1995) J. Biol. Chem. 270, 5659-5665
36. Ylänne, J., Scheffzek, K., Young, P., and Saraste, M. (2001) Structure 9, 597-604