Developmental and morphological regulation of clathrin-mediated endocytosis in Trypanosoma brucei

Journal of Cell Science

Volumn 114, Issue 14, 2001, Pages 2605-2615

  Morgan, G W ^a   Allen, C L ^a   Jeffries, T R ^a   Hollinshead, M ^a   Field, M C ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Adaptin; Clathrin; Endocytosis; Endosome; Trypanosome; VSG

Indexed keywords

ADAPTOR PROTEIN; BETA ADAPTIN; CLATHRIN; CLATHRIN HEAVY CHAIN; COAT PROTEIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ARTICLE; BIOCHEMISTRY; BLOOD FLOW; CELL VACUOLE; CHEMICAL COMPOSITION; COATED PIT; CONTROLLED STUDY; DEVELOPMENT; DISEASE CARRIER; ELECTRON MICROSCOPY; ENDOCYTOSIS; FLAGELLUM; FRACTIONATION; GOLGI COMPLEX; HOST; IMMUNE SYSTEM; MACROMOLECULE; MODULATION; MOLECULAR BIOLOGY; MOLECULAR CLONING; MORPHOLOGY; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; STAGING; TRYPANOSOMA BRUCEI; TRYPOMASTIGOTE; ULTRASTRUCTURE; VERTEBRATE;

ADAPTOR PROTEIN COMPLEX BETA SUBUNITS; ANIMALS; CLATHRIN; CLATHRIN HEAVY CHAINS; CLATHRIN-COATED VESICLES; CONSERVED SEQUENCE; ENDOCYTOSIS; ENDOSOMES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; TRANSPORT VESICLES; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0034909962     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Molecular cloning and cellular localisation of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals
2. Surface coats and secretory trafficking in African trypanosomes
3. Low temperature reversibly inhibits transport from tubular endosomes to a perinuclear, acidic compartment
4. Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: Purification and involvement in the growth of the parasite
5. Assembly and packing of clathrin into coats
6. AP-3: An adaptor-like protein complex with ubiquitous expression
7. Association of the AP-3 adaptor complex with clathrin
8. AP-4, a novel protein complex related to clathrin adaptors
9. Tandem duplication of Rab genes followed by sequence divergence and acquisition of distinct functions in Trypanosoma brucei
10. Complexity of trypanosomatid endocytosis pathways revealed by Rab4 and Rab5 isoforms in Trypanosoma brucei
11. Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei
12. In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules
13. Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain
14. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
15. Deep-etch visualisation of proteins involved in clathrin assembly
16. Characterization of a fourth adaptor-related protein complex
17. Clathrin and adaptors
18. A developmentally regulated Rab11 homologue in Trypanosoma brucei is involved in recycling processes
19. Adaptors for clathrin-mediated traffic
20. Clathrin
21. Protein organization in clathrin trimmers
22. Protein uptake and digestion in bloodstream and culture forms of Trypanosoma brucei
23. Receptor mediated endocytosis in the procyclic form of Trypanosoma brucei
24. Both IgM and IgG anti-VSG antibodies initiate a cycle of aggregation-disaggregation of bloodstream forms of Trypanosoma brucei without damage to the parasite
25. Endocytosis and secretion in trypanosomatid parasites-tumultuous traffic in a pocket
26. The structure and function of the beta2-adaptin appendage domain
27. A novel structural model of clathrin function
28. Clathrin coats - Threads laid bare
29. Phylogenetic analysis of components of the eukaryotic vesicle transport system reveals a common origin of adaptor complexes 1, 3, and 3 and the F sub-complex of coatomer COPI
30. Coated vesicles from the protozoan parasite Trypanosoma brucei: Purification and characterisation
31. A clathrin-binding site in the hinge of the beta2 chain of mammalian AP-2 complexes
32. Characterization of the adaptor-related protein complex, AP-3
33. Clathrin, adaptors and eps15 in endosomes containing activated epidermal growth factor receptors
34. ESAG 6 and 7 products of Trypanosoma brucei form a transferrin binding protein complex
35. PAUP* phylogenetic analysis using parsimony
36. Atomic structure of clathrin: A beta propeller terminal domain joins an alpha zigzag linker
37. Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin
38. Assembly units of clathrin coats
39. Trypanosoma brucei: A membrane-associated protein in coated endocytic vesicles
40. The flagellar pocket of trypanosomatids
41. A novel method mean cell volume estimation
42. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis
43. Timing of nuclear and and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei